Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04310 Wnt signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04371 Apelin signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04020 Calcium signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04070 Phosphatidylinositol signaling system
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04072 Phospholipase D signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04071 Sphingolipid signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04022 cGMP-PKG signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04613 Neutrophil extracellular trap formation
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04621 NOD-like receptor signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04062 Chemokine signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09152 Endocrine system
04911 Insulin secretion
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04922 Glucagon signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04929 GnRH secretion
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04912 GnRH signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04915 Estrogen signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04921 Oxytocin signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04926 Relaxin signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04935 Growth hormone synthesis, secretion and action
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04918 Thyroid hormone synthesis
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04919 Thyroid hormone signaling pathway
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04928 Parathyroid hormone synthesis, secretion and action
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04916 Melanogenesis
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04924 Renin secretion
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04925 Aldosterone synthesis and secretion
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04927 Cortisol synthesis and secretion
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04270 Vascular smooth muscle contraction
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09154 Digestive system
04970 Salivary secretion
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04971 Gastric acid secretion
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04972 Pancreatic secretion
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04973 Carbohydrate digestion and absorption
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09155 Excretory system
04961 Endocrine and other factor-regulated calcium reabsorption
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09156 Nervous system
04724 Glutamatergic synapse
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04725 Cholinergic synapse
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04728 Dopaminergic synapse
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04726 Serotonergic synapse
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04720 Long-term potentiation
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04730 Long-term depression
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04723 Retrograde endocannabinoid signaling
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09157 Sensory system
04745 Phototransduction - fly
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04742 Taste transduction
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04750 Inflammatory mediator regulation of TRP channels
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09158 Development and regeneration
04361 Axon regeneration
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09159 Environmental adaptation
04713 Circadian entrainment
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09171 Infectious disease: bacterial
05131 Shigellosis
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09174 Infectious disease: parasitic
05146 Amoebiasis
K05858 PLCB; phosphatidylinositol phospholipase C, beta
05142 Chagas disease
K05858 PLCB; phosphatidylinositol phospholipase C, beta
05143 African trypanosomiasis
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09164 Neurodegenerative disease
05010 Alzheimer disease
K05858 PLCB; phosphatidylinositol phospholipase C, beta
05016 Huntington disease
K05858 PLCB; phosphatidylinositol phospholipase C, beta
05017 Spinocerebellar ataxia
K05858 PLCB; phosphatidylinositol phospholipase C, beta
05022 Pathways of neurodegeneration - multiple diseases
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
K05858 PLCB; phosphatidylinositol phospholipase C, beta
05415 Diabetic cardiomyopathy
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
K05858 PLCB; phosphatidylinositol phospholipase C, beta
04934 Cushing syndrome
K05858 PLCB; phosphatidylinositol phospholipase C, beta
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking
K05858 PLCB; phosphatidylinositol phospholipase C, beta
Enzymes [BR:ko01000 ]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
K05858 PLCB; phosphatidylinositol phospholipase C, beta
Membrane trafficking [BR:ko04131 ]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
K05858 PLCB; phosphatidylinositol phospholipase C, beta
Endocytosis
Macropinocytosis
Phospholipase C
K05858 PLCB; phosphatidylinositol phospholipase C, beta
BRITE hierarchy
Authors
Alvarez RA, Ghalayini AJ, Xu P, Hardcastle A, Bhattacharya S, Rao PN, Pettenati MJ, Anderson RE, Baehr W