KEGG   ORTHOLOGY: K05863
Entry
K05863                      KO                                     

Name
SLC25A4S, ANT
Definition
solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04217  Necroptosis
ko04218  Cellular senescence
ko04613  Neutrophil extracellular trap formation
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05016  Huntington disease
ko05017  Spinocerebellar ataxia
ko05020  Prion disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05164  Influenza A
ko05166  Human T-cell leukemia virus 1 infection
Disease
H00469  Mitochondrial DNA depletion syndrome
H01118  Progressive external ophthalmoplegia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   04022 cGMP-PKG signaling pathway
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   04218 Cellular senescence
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   05012 Parkinson disease
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   05016 Huntington disease
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   05017 Spinocerebellar ataxia
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   05020 Prion disease
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   05022 Pathways of neurodegeneration - multiple diseases
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
   05164 Influenza A
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial transcription and translation factors
   Other mitochondrial DNA transcription and translation factors
    K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC25: Mitochondrial carrier
   K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
Other DBs
GO: 0015207
TC: 2.A.29.1
Genes
HSA: 291(SLC25A4) 292(SLC25A5) 293(SLC25A6) 83447(SLC25A31)
PTR: 101057286 107972834 112206875(SLC25A6) 461632(SLC25A4) 736938(SLC25A5) 742937(SLC25A31)
PPS: 100971042(SLC25A4) 100981051 100984012(SLC25A31) 100991246(SLC25A5)
GGO: 101132025(SLC25A4) 101138376(SLC25A5) 101143704(SLC25A31)
PON: 100173820(SLC25A5) 100432368(SLC25A31) 100437258(SLC25A4) 100445977(SLC25A6) 100445983
NLE: 100582353(SLC25A5) 100599131(SLC25A31) 100601532(SLC25A4)
MCC: 693502(SLC25A5) 695102(SLC25A4) 710042(SLC25A31) 719811
MCF: 102120762(SLC25A4) 102129825(SLC25A6) 102138876(SLC25A5) 102143674(SLC25A31)
CSAB: 103220507 103236238(SLC25A31) 103236621(SLC25A4) 103247334(SLC25A5) 103247519(SLC25A6)
RRO: 104661254 104663348(SLC25A6) 104673801(SLC25A4) 104673881(SLC25A5) 115899258
CJC: 100387000(SLC25A5) 100397220(SLC25A31) 100403424(SLC25A6) 100405844(SLC25A6) 100411371(SLC25A4) 100415405 108588056
MMU: 11739(Slc25a4) 11740(Slc25a5) 73333(Slc25a31)
MCAL: 110286753(Slc25a5) 110291352(Slc25a31) 110300115(Slc25a4)
MPAH: 110313362(Slc25a5) 110320569(Slc25a31) 110336417(Slc25a4)
RNO: 100909799 25176(Slc25a5) 689108(Slc25a31) 85333(Slc25a4)
MUN: 110556812(Slc25a4) 110566446(Slc25a5) 110566972(Slc25a31)
CGE: 100751779(Slc25a4) 100761654 100769087(Slc25a5) 100773145(Slc25a31)
NGI: 103726219(Slc25a31) 103742868(Slc25a5) 103750115(Slc25a6) 103750480(Slc25a4)
HGL: 101697130(Slc25a5) 101698774(Slc25a31) 101703823(Slc25a6) 101706144(Slc25a4)
CCAN: 109675843 109681419(Slc25a31) 109684937(Slc25a4) 109688777(Slc25a6)
OCU: 100009414(SLC25A4) 100337764(SLC25A5) 100346477(SLC25A31) 100349768 100356326
TUP: 102469729 102470597(SLC25A5) 102475617(SLC25A6) 102480098 102488121(SLC25A31) 102493892(SLC25A4)
CFA: 475630(SLC25A4) 480830(SLC25A6) 483832(SLC25A31) 492093(SLC25A5)
VVP: 112908953(SLC25A6) 112910590(SLC25A5) 112931611(SLC25A31) 112934741(SLC25A4)
AML: 100464085(SLC25A31) 100469507(SLC25A6) 100473508(SLC25A4) 100476732(SLC25A5)
UMR: 103656991(SLC25A31) 103666331(SLC25A6) 103677737(SLC25A5) 103681007(SLC25A4)
UAH: 113240791(SLC25A6) 113241271(SLC25A5) 113255470(SLC25A31) 113262270(SLC25A4)
ORO: 101366629(SLC25A31) 101367537 101371414 101372733(SLC25A4) 101374224 101384049(SLC25A6)
FCA: 101082635(SLC25A5) 101086294(SLC25A31) 101096309(SLC25A4) 101100868(SLC25A6) 111558717
PTG: 102960718(SLC25A4) 102962163 102966182(SLC25A6) 102971432(SLC25A31) 102972215(SLC25A5)
PPAD: 109249044(SLC25A31) 109250770(SLC25A5) 109251009(SLC25A4) 109256146(SLC25A6)
AJU: 106970899(SLC25A5) 106982044(SLC25A6) 106982226(SLC25A4) 106988175(SLC25A31)
BTA: 282478(SLC25A4) 282479(SLC25A5) 282480(SLC25A6) 541168(SLC25A31) 787122
BOM: 102275932(SLC25A5) 102280125(SLC25A6) 102286445(SLC25A4) 102287077(SLC25A31)
BIU: 109553455(SLC25A4) 109561148 109571027(SLC25A31)
BBUB: 102400898(SLC25A6) 102405012(SLC25A31) 102413768(SLC25A4) 102415498(SLC25A5)
CHX: 100861351(SLC25A4) 102173075(SLC25A5) 102176546(SLC25A31) 102178813(SLC25A6)
OAS: 100147787(SLC25A4) 100147789(SLC25A6) 101122465(SLC25A31)
SSC: 100158185(SLC25A5) 100517196(SLC25A4) 100518564(SLC25A31) 403155(SLC25A6)
CFR: 102503644(SLC25A31) 102512378(SLC25A6) 102513318(SLC25A4) 102516285(SLC25A5) 102520419
CDK: 105084439(SLC25A4) 105087057(SLC25A31) 105093951(SLC25A5) 105103090(SLC25A6)
BACU: 102999263(SLC25A4) 103009487(SLC25A6) 103012312(SLC25A5) 103012461(SLC25A31)
LVE: 103068650(SLC25A31) 103075399(SLC25A4) 103083138(SLC25A6) 103091053(SLC25A5)
OOR: 101275776(SLC25A5) 101278211(SLC25A31) 101279540(SLC25A6) 101288695(SLC25A4)
DLE: 111165889(SLC25A31) 111168263(SLC25A6) 111169059(SLC25A5) 111173410(SLC25A4)
PCAD: 102975203(SLC25A5) 102978018(SLC25A31) 102985148(SLC25A6) 102990817(SLC25A4) 102996437
ECB: 100050762(SLC25A4) 100059103(SLC25A5) 100071908(SLC25A31) 100146128(SLC25A6)
EPZ: 103540840 103545106 103549138(SLC25A4) 103562821(SLC25A31)
EAI: 106829894(SLC25A31) 106830087(SLC25A4) 106841502(SLC25A5) 106842512(SLC25A6)
MYB: 102239133(SLC25A31) 102246203 102255058(SLC25A4) 102256266 102256951(SLC25A5)
MNA: 107529320(SLC25A5) 107529763(SLC25A31) 107535760(SLC25A4) 107542290 107543961
HAI: 109374086 109375563(SLC25A6) 109390884 109394950(SLC25A31) 109395862(SLC25A4)
DRO: 112301943 112306713(SLC25A4) 112310580(SLC25A5) 112312642(SLC25A31) 112313387(SLC25A6)
PALE: 102878001(SLC25A4) 102885895 102896364(SLC25A6) 102896575(SLC25A5) 102897294(SLC25A31)
RAY: 107498648 107506524(SLC25A5) 107510449(SLC25A4) 107512501(SLC25A31) 107512547(SLC25A6)
MJV: 108386810(SLC25A5) 108389683(SLC25A6) 108396047(SLC25A31) 108410160(SLC25A4)
LAV: 100655324(SLC25A6) 100662489(SLC25A4) 100664844(SLC25A5) 100669563(SLC25A31)
SHR: 100920060(SLC25A4) 100929945(SLC25A31) 116422319(SLC25A6)
PCW: 110209837(SLC25A31) 110212779(SLC25A6) 110220099 110222593(SLC25A4)
OAA: 100080434(SLC25A5) 100087351(SLC25A4) 114812883(SLC25A31)
GGA: 374072(SLC25A6) 422546(SLC25A4) 772225(SLC25A5)
MGP: 100545489(SLC25A5) 100547105(SLC25A4) 100547970(SLC25A6)
CJO: 107305856(SLC25A6) 107312944(SLC25A5) 107313279(SLC25A4)
NMEL: 110398592(SLC25A4) 110403250(SLC25A5) 110405908(SLC25A6)
APLA: 101791414(SLC25A5) 101794225(SLC25A4) 101799034(SLC25A6)
ACYG: 106035124(SLC25A4) 106035685(SLC25A6) 106037651(SLC25A5) 106042436(SLC25A31)
TGU: 100190145(SLC25A5) 100190146(SLC25A6) 100227980(SLC25A4)
LSR: 110476947(SLC25A4) 110479392(SLC25A6) 110480478(SLC25A5)
SCAN: 103812627(SLC25A6) 103816532(SLC25A5) 103825605(SLC25A4)
GFR: 102031695(SLC25A4) 102038498(SLC25A6) 102039001(SLC25A5)
FAB: 101810172(SLC25A4) 101815466(SLC25A5) 101818491(SLC25A6)
PHI: 102105225(SLC25A4) 102110337(SLC25A5) 102112843(SLC25A6)
PMAJ: 107201509(SLC25A6) 107203619(SLC25A4) 107203940(SLC25A5)
CCAE: 111928433(SLC25A4) 111944386 111944525(SLC25A6)
CCW: 104686297(SLC25A6) 104690855(SLC25A4) 104694471(SLC25A5)
ETL: 114055574(SLC25A4) 114065037(SLC25A5) 114066994(SLC25A6)
FPG: 101911995(SLC25A5) 101917366(SLC25A6) 101917374(SLC25A4) 101923649(SLC25A31)
FCH: 102052754(SLC25A5) 102056660(SLC25A4) 102057129(SLC25A6) 102058611(SLC25A31)
CLV: 102090099(SLC25A5) 102094223(SLC25A6) 102096475(SLC25A4)
EGZ: 104124066(SLC25A5) 104125138(SLC25A6) 104129313(SLC25A31) 104129432(SLC25A4)
NNI: 104009846(SLC25A6) 104015971(SLC25A31) 104019084(SLC25A5) 104021290(SLC25A4)
ACUN: 113478665(SLC25A6) 113479234(SLC25A4) 113480143(SLC25A5)
PADL: 103922565(SLC25A4) 103923034(SLC25A5) 103923051(SLC25A6) 103926144(SLC25A31)
AAM: 106483997 106487533(SLC25A5) 106490690(SLC25A6) 106491850(SLC25A31)
ASN: 102371094(SLC25A4) 102376128(SLC25A5) 102384953 102387986(SLC25A31)
AMJ: 102562521(SLC25A6) 102565969(SLC25A31) 102576169(SLC25A4) 106736959(SLC25A5)
PSS: 102444939(SLC25A31) 102446093(SLC25A5) 102458327(SLC25A6) 102461807(SLC25A4)
CMY: 102930600(SLC25A4) 102940968(SLC25A6) 102941037(SLC25A5) 102943274(SLC25A31)
CPIC: 101935127(SLC25A31) 101937873(SLC25A6) 101947225(SLC25A5) 101952179(SLC25A4)
ACS: 100554158(slc25a6) 100557696(slc25a31) 100558779(slc25a5) 100563345(slc25a4)
PVT: 110072866(SLC25A31) 110083822(SLC25A4) 110089751 110090254(SLC25A5)
PMUR: 107289684 107290576(SLC25A31) 107301632 107302668(SLC25A4)
TSR: 106540012(SLC25A4) 106546231(SLC25A31) 106547817 106552730
PMUA: 114589016(SLC25A5) 114596329(SLC25A6) 114604061(SLC25A31) 114604671(SLC25A4)
GJA: 107108997(SLC25A31) 107116719(SLC25A4) 107120378(SLC25A6) 107123722(SLC25A5)
XLA: 100126647(slc25a31.L) 108700136 108705979 380187(slc25a5.L) 432212(slc25a4.L)
XTR: 394504(slc25a4) 394508(slc25a5)
NPR: 108790928(SLC25A4) 108798305(SLC25A5)
DRE: 100038774(si:dkey-251i10.1) 192321(slc25a5) 327067(slc25a4) 566370(slc25a6)
IPU: 100528279(adt3) 100528860(slc25a5) 108260169 108260845(slc25a4) 108266970(SLC25A5) 108273102(SLC25A4)
TRU: 743354(ants6) 751094(slc25a5) 751095(slc25a4)
PRET: 103466173(slc25a4) 103471639 103471640(slc25a5) 103475848
KMR: 108231435(slc25a5) 108244015(slc25a4) 108248808(si:dkey-251i10.1)
AOCE: 111575325(slc25a4) 111578216 111587178
BPEC: 110158394 110158852 110165268(slc25a4)
SASA: 100194655 106563614(ADT2) 106602726(slc25a4) 106603043 106604721(ADT2) 106611749(ADT2)
ELS: 105010883 105021093(slc25a4) 105029427(adt2) 105031340
LCM: 102347011(SLC25A5) 102349731 102350158(SLC25A31) 102356552(SLC25A4)
CMK: 103178208(slc25a4) 103178409(slc25a5) 103190058(slc25a31)
RTP: 109914009 109924065 109928789(slc25a31)
DME: Dmel_CG1683(Ant2) Dmel_CG16944(sesB)
DSI: Dsimw501_GD16013(Dsim_GD16013) Dsimw501_GD16014(Dsim_GD16014)
DYA: Dyak_GE15371(Dyak_sesB) Dyak_GE15372
DPO: Dpse_GA14170 Dpse_GA14229(Dpse_sesB)
MDE: 101889408
AGA: AgaP_AGAP002358(ADT2_ANOGA) AgaP_AGAP006782(ADT1_ANOGA)
AME: 107964398 406075(Ant)
HST: 105185646
LHU: 105675415
NVI: 100117058
MDL: 103577361
BMOR: 101738591 692626(Ant)
BTAB: 109037679
ZNE: 110836319
DPTE: 113792844
CEL: CELE_C47E12.2(C47E12.2) CELE_F25B4.7(F25B4.7) CELE_K01H12.2(ant-1.3) CELE_R07E3.4(R07E3.4) CELE_T01B11.4(ant-1.4) CELE_T27E9.1(ant-1.1) CELE_W02D3.6(ant-1.2)
CBR: CBG03436 CBG03723(Cbr-tag-316) CBG09342 CBG17210 CBG20451 CBG21201(Cbr-tag-61)
TSP: Tsp_01983
MYI: 110465105
OBI: 106870577
SHX: MS3_03206
EGL: EGR_03392
DGT: 114520366
HMG: 105843221
ATH: AT3G08580(AAC1) AT4G28390(AAC3) AT5G13490(AAC2) AT5G17400(ER-ANT1) AT5G56450(PM-ANT)
LJA: Lj0g3v0065999.1(Lj0g3v0065999.1) Lj0g3v0073249.1(Lj0g3v0073249.1) Lj0g3v0251339.1(Lj0g3v0251339.1) Lj0g3v0251339.2(Lj0g3v0251339.2) Lj0g3v0251339.3(Lj0g3v0251339.3) Lj0g3v0350069.1(Lj0g3v0350069.1) Lj1g3v1786120.1(Lj1g3v1786120.1) Lj2g3v0661560.1(Lj2g3v0661560.1) Lj3g3v0840550.1(Lj3g3v0840550.1) Lj3g3v2809810.1(Lj3g3v2809810.1) Lj4g3v3114850.1(Lj4g3v3114850.1)
DOSA: Os02t0718900-01(Os02g0718900) Os05t0302700-01(Os05g0302700) Os05t0539600-01(Os05g0539600) Os11t0661300-01(Os11g0661300)
ATS: 109744107(LOC109744107) 109745669(LOC109745669) 109770094(LOC109770094) 109776847(LOC109776847) 109778805(LOC109778805)
ZMA: 100274442 100282898 100284305(gpm280a) 103630666 542386(ANT1) 542389(ANT2)
SCE: YBL030C(PET9) YBR085W(AAC3) YMR056C(AAC1)
ERC: Ecym_7441
KMX: KLMA_70354(AAC)
NCS: NCAS_0A08210(NCAS0A08210) NCAS_0A10880(NCAS0A10880) NCAS_0I01330(NCAS0I01330)
NDI: NDAI_0A05420(NDAI0A05420) NDAI_0A07670(NDAI0A07670) NDAI_0G04660(NDAI0G04660)
TPF: TPHA_0M01360(TPHA0M01360) TPHA_0N01580(TPHA0N01580)
TBL: TBLA_0G03560(TBLA0G03560)
TDL: TDEL_0B07140(TDEL0B07140) TDEL_0F02010(TDEL0F02010)
KAF: KAFR_0B05170(KAFR0B05170) KAFR_0C00210(KAFR0C00210)
PIC: PICST_45104(PET9) PICST_85436(ADT1)
CAL: CAALFM_C500590WA(PET9)
SLB: AWJ20_4572(PET9)
NCR: NCU09477(aac)
NTE: NEUTE1DRAFT130134(NEUTE1DRAFT_130134)
MGR: MGG_16149
SSCK: SPSK_01245
MAW: MAC_03644
MAJ: MAA_02544
CMT: CCM_00240
MBE: MBM_07006
ANI: AN4064.2
ANG: ANI_1_558164(An18g04220)
ABE: ARB_05611
TVE: TRV_07210
PTE: PTT_16860
SPO: SPBC530.10c(anc1)
TASA: A1Q1_01637
ABP: AGABI1DRAFT110533(AGABI1DRAFT_110533)
ABV: AGABI2DRAFT189567(AGABI2DRAFT_189567)
MGL: MGL_3651
MRT: MRET_2596
DDI: DDB_G0267454(ancA)
PCB: PCHAS_052040(PC000019.01.0)
TPV: TP02_0141
BBO: BBOV_III010060(17.m07874)
CPV: cgd8_1210
SMIN: v1.2.036479.t1(symbB.v1.2.036479.t1) v1.2.042182.t1(symbB.v1.2.042182.t1)
TPS: THAPSDRAFT_39143(ANT1)
LMA: LMJF_19_0200(ANC1) LMJF_19_0210(ANC2)
LIF: LINJ_19_0190(ANC1) LINJ_19_0200(ANC2)
LPAN: LPMP_190170(ANC1) LPMP_190180(ANC2)
 » show all
Reference
PMID:2823266
  Authors
Neckelmann N, Li K, Wade RP, Shuster R, Wallace DC
  Title
cDNA sequence of a human skeletal muscle ADP/ATP translocator: lack of a leader peptide, divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes.
  Journal
Proc Natl Acad Sci U S A 84:7580-4 (1987)
DOI:10.1073/pnas.84.21.7580
  Sequence
[hsa:291]
Reference
  Authors
Kim YH, Haidl G, Schaefer M, Egner U, Mandal A, Herr JC
  Title
Compartmentalization of a unique ADP/ATP carrier protein SFEC (Sperm Flagellar Energy Carrier, AAC4) with glycolytic enzymes in the fibrous sheath of the human sperm flagellar principal piece.
  Journal
Dev Biol 302:463-76 (2007)
DOI:10.1016/j.ydbio.2006.10.004
  Sequence
[hsa:83447] [mmu:73333]

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