KEGG   ORTHOLOGY: K05869
Entry
K05869                      KO                                     
Symbol
CAMK4
Name
calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
Pathway
map04020  Calcium signaling pathway
map04024  cAMP signaling pathway
map04211  Longevity regulating pathway
map04371  Apelin signaling pathway
map04380  Osteoclast differentiation
map04720  Long-term potentiation
map04722  Neurotrophin signaling pathway
map04725  Cholinergic synapse
map04921  Oxytocin signaling pathway
map04925  Aldosterone synthesis and secretion
map05031  Amphetamine addiction
map05034  Alcoholism
map05214  Glioma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
   04020 Calcium signaling pathway
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
   04024 cAMP signaling pathway
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
   04925 Aldosterone synthesis and secretion
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
  09156 Nervous system
   04725 Cholinergic synapse
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
   04720 Long-term potentiation
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
   04722 Neurotrophin signaling pathway
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
  09149 Aging
   04211 Longevity regulating pathway
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
 09160 Human Diseases
  09162 Cancer: specific types
   05214 Glioma
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
  09165 Substance dependence
   05031 Amphetamine addiction
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
   05034 Alcoholism
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.17  Ca2+/calmodulin-dependent protein kinase
     K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CAMK group
  CAMK1 family [OT]
   K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV
Other DBs
GO: 0004683
Genes
HSA: 814(CAMK4)
PTR: 461992(CAMK4)
PPS: 100970371(CAMK4)
GGO: 101140371(CAMK4)
PON: 100461605(CAMK4)
NLE: 100583900(CAMK4)
MCC: 712322(CAMK4)
MCF: 101864901(CAMK4)
CSAB: 103244326(CAMK4)
CATY: 105576638(CAMK4)
PANU: 101009081(CAMK4)
TGE: 112626099(CAMK4)
RRO: 104677657(CAMK4)
RBB: 108540302(CAMK4)
TFN: 117064830(CAMK4)
PTEH: 111542684(CAMK4)
CJC: 100388410(CAMK4)
SBQ: 101053463(CAMK4)
CSYR: 103253937 103264715(CAMK4)
MMUR: 105865738(CAMK4)
LCAT: 123648496(CAMK4)
OGA: 100963188(CAMK4)
MMU: 12326(Camk4)
MCAL: 110284636(Camk4)
MPAH: 110333240(Camk4)
RNO: 25050(Camk4)
MCOC: 116086957(Camk4)
MUN: 110564828(Camk4)
CGE: 100774010(Camk4)
MAUA: 101841141(Camk4)
PLEU: 114691636(Camk4)
MORG: 121445161(Camk4) 121453240
AAMP: 119814676(Camk4)
NGI: 103752296(Camk4)
HGL: 101700365(Camk4)
CPOC: 100723881(Camk4)
CCAN: 109696025(Camk4)
DORD: 105988651(Camk4)
DSP: 122118075(Camk4)
NCAR: 124987181
OCU: 103345118(CAMK4)
OPI: 101525109(CAMK4)
TUP: 102479520(CAMK4)
CFA: 100684140(CAMK4)
CLUD: 112653311(CAMK4)
VVP: 112915439(CAMK4)
VLG: 121489316(CAMK4)
AML: 100473015(CAMK4)
UMR: 103675811(CAMK4)
UAH: 113254999(CAMK4)
UAR: 123779312(CAMK4)
ELK: 111148267
LLV: 125099686
MPUF: 101677801(CAMK4)
ORO: 101369425(CAMK4)
EJU: 114208735(CAMK4)
ZCA: 113929737(CAMK4)
MLX: 118017609(CAMK4)
FCA: 101095400(CAMK4)
PYU: 121012085(CAMK4)
PBG: 122491922(CAMK4)
PTG: 102954895(CAMK4)
PPAD: 109267609(CAMK4)
AJU: 106975674(CAMK4)
HHV: 120224722(CAMK4)
BTA: 100337083(CAMK4)
BOM: 102264521(CAMK4)
BBUB: 102389738(CAMK4)
CHX: 102187484(CAMK4)
OAS: 101108308(CAMK4)
ODA: 120863455(CAMK4)
CCAD: 122439461(CAMK4)
SSC: 100515364(CAMK4)
CFR: 102503715(CAMK4)
CBAI: 105082027(CAMK4)
CDK: 105095388(CAMK4)
VPC: 102539084(CAMK4)
BACU: 102998672(CAMK4)
LVE: 103081119(CAMK4)
OOR: 101273696(CAMK4)
DLE: 111183716(CAMK4)
PCAD: 102984487(CAMK4)
PSIU: 116751210(CAMK4)
ECB: 100073192(CAMK4)
EPZ: 103550069(CAMK4)
EAI: 106832342(CAMK4)
MYB: 102254489(CAMK4)
MYD: 102761359(CAMK4)
MMYO: 118656630(CAMK4)
MLF: 102433506(CAMK4)
MNA: 107546482(CAMK4)
PKL: 118702878(CAMK4)
HAI: 109391534(CAMK4)
DRO: 112307173(CAMK4)
SHON: 118977337(CAMK4)
AJM: 119065119(CAMK4)
PDIC: 114511230(CAMK4)
PHAS: 123818083(CAMK4)
MMF: 118641608(CAMK4)
RFQ: 117024996(CAMK4)
PALE: 102879333(CAMK4)
PGIG: 120590812(CAMK4)
PVP: 105295473(CAMK4)
RAY: 107506545(CAMK4)
MJV: 108390709(CAMK4)
TOD: 119260183(CAMK4)
SARA: 101540320(CAMK4)
LAV: 100671333(CAMK4)
TMU: 101343253
DNM: 101428221(CAMK4)
MDO: 100015956(CAMK4)
GAS: 123231353(CAMK4)
SHR: 100920792(CAMK4)
PCW: 110222132(CAMK4)
OAA: 100076517 100082421(CAMK4)
GGA: 427267(CAMK4L) 723973(CAMK4)
PCOC: 116235788 116239726(CAMK4)
MGP: 100551031(CAMK4)
CJO: 107306359(CAMK4) 107325456
NMEL: 110388918 110389600(CAMK4)
APLA: 101802471(CAMK4) 101804940
ACYG: 106042351(CAMK4) 106048195
AFUL: 116498973 116500451(CAMK4)
TGU: 100219262(CAMK4)
LSR: 110467596(CAMK4) 110480196
SCAN: 103822052 103824116(CAMK4)
PMOA: 120513733(CAMK4) 120513887
OTC: 121333115(CAMK4) 121341470
PRUF: 121353393(CAMK4) 121360792
GFR: 102038357 102040809(CAMK4)
FAB: 101810211(CAMK4) 101818551
PHI: 102112643 102114009(CAMK4)
PMAJ: 107215374 107216227(CAMK4)
CCAE: 111940603(CAMK4) 111944618
CCW: 104693208(CAMK4) 104697064
CBRC: 103611663(CAMK4) 103622189
ETL: 114054669(CAMK4) 114066382
ZAB: 102063028(CAMK4)
FPG: 101913113(CAMK4) 101917352
FCH: 102050248(CAMK4) 102054662
CLV: 102093272 102098059(CAMK4)
EGZ: 104128295 104135038(CAMK4)
NNI: 104022203(CAMK4)
PLET: 104622422
ACUN: 113489308 113489531(CAMK4)
TALA: 104364147(CAMK4) 116960315
PADL: 103920872(CAMK4)
ACHC: 115337069(CAMK4) 115348857
HALD: 104324104(CAMK4)
EHS: 104515751(CAMK4)
CMAC: 104483561(CAMK4) 104484995
FGA: 104082746
OHA: 104332557 104337839(CAMK4)
AROW: 112963117(CAMK4)
NPD: 112958903(CAMK4)
DNE: 112995231(CAMK4)
ASN: 102370467(CAMK4) 102377785
AMJ: 102566359(CAMK4) 102571105
CPOO: 109308169(CAMK4) 109312309
GGN: 109294946 109298085(CAMK4)
PSS: 102460870(CAMK4)
CMY: 102942278 102943759(CAMK4)
CPIC: 101930944 101933258(CAMK4)
TST: 117869013 117879161(CAMK4)
MRV: 120391518 120407698(CAMK4)
ACS: 100559276(camk4) 100564355
PVT: 110072022(CAMK4) 110072612
SUND: 121923953(CAMK4) 121937118
TSR: 106553245(CAMK4)
PGUT: 117668620 117674636(CAMK4)
VKO: 123031477(CAMK4) 123036575
PMUA: 114588515 114606108(CAMK4)
ZVI: 118077001(CAMK4) 118086017
STOW: 125436723(CAMK4)
XLA: 108707217(camk4.S) 108712576 373837(camk4.L)
XTR: 100490912(camk4) 100496389
NPR: 108792885(CAMK4) 108793483
RTEM: 120913605 120931671(CAMK4)
BBUF: 120989445 120992568(CAMK4)
BGAR: 122930211 122935459(CAMK4)
DRE: 550270(camk4)
CCAR: 109053483 109108254(camk4)
PPRM: 120472259(camk4)
MAMB: 125267898(camk4)
IPU: 108260461(camk4)
PHYP: 113531350(camk4) 113546396
SMEO: 124378883(camk4)
TFD: 113640876(camk4)
AMEX: 103044753(camk4)
EEE: 113586933(camk4)
TRU: 101066536(camk4)
NCC: 104962492
CGOB: 115007617
ELY: 117253336(si:ch73-60h1.1)
EFO: 125895572(si:ch73-60h1.1)
PLEP: 121939058
SLUC: 116059162(si:ch73-60h1.1)
PFLV: 114561522(camk4)
GAT: 120823668(si:ch73-60h1.1)
PPUG: 119216309(si:ch73-60h1.1)
MSAM: 119888480 119888860(si:ch73-60h1.1)
CUD: 121512456(si:ch73-60h1.1)
ALAT: 119028565(si:ch73-60h1.1)
OAU: 116333055(si:ch73-60h1.1)
OLA: 101155594
OML: 112150356(si:ch73-60h1.1)
XCO: 114150793
XHE: 116725306(camk4)
PRET: 103463153
PFOR: 103153785
PLAI: 106963847
PMEI: 106927092
GAF: 122838543(si:ch73-60h1.1)
CVG: 107103959(camk4)
CTUL: 119784688(si:ch73-60h1.1)
GMU: 124873458(si:ch73-60h1.1)
NFU: 107393094
KMR: 108248674(si:ch73-60h1.1)
ALIM: 106531135(camk4)
NWH: 119430477(si:ch73-60h1.1)
AOCE: 111575981(camk4)
MCEP: 125009788(si:ch73-60h1.1)
CSEM: 103399037(camk4)
POV: 109644251
SSEN: 122780873(si:ch73-60h1.1)
HHIP: 117759836(si:ch73-60h1.1)
HSP: 118121571(si:ch73-60h1.1)
LCF: 108891760(camk4)
SDU: 111231823
XGL: 120790665(si:ch73-60h1.1)
HCQ: 109506827(camk4)
BPEC: 110162797
MALB: 109965258(camk4)
BSPL: 114853345(si:ch73-60h1.1)
SNH: 120026046(camk4) 120044212 120053921(si:ch73-60h1.1)
ELS: 105011406 105027933(camk4)
SFM: 108925114(camk4) 108930508
PKI: 111836089(camk4) 111844630
AANG: 118213173(camk4) 118226327(si:ch73-60h1.1)
LOC: 102690113(camk4)
LCM: 102362167(CAMK4)
BFO: 118408272
CIN: 100176025
SCLV: 120334047
SPU: 592450
APLC: 110988799
SKO: 100373179
AGIF: 122858453
CCIN: 107273926
HHAL: 106682708
NLU: 111053087
FOC: 113208521
TPAL: 117641377
ZNE: 110829799
CSEC: 111863842
FCD: 110859869
PCAN: 112554592
GAE: 121382235
HRF: 124135750
HRJ: 124255779
PMAX: 117333954
MMER: 123523169
OBI: 106870421
LAK: 106159758
EPA: 110250062
ADF: 107345984
AMIL: 114959403
SPIS: 111321760
DGT: 114534474
XEN: 124456188
HMG: 100213537
 » show all
Reference
PMID:8065343
  Authors
Matthews RP, Guthrie CR, Wailes LM, Zhao X, Means AR, McKnight GS
  Title
Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.
  Journal
Mol Cell Biol 14:6107-16 (1994)
DOI:10.1128/MCB.14.9.6107
  Sequence
[rno:25050]
Reference
PMID:8107230
  Authors
Mosialos G, Hanissian SH, Jawahar S, Vara L, Kieff E, Chatila TA
  Title
A Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, expressed after transformation of primary human B lymphocytes by Epstein-Barr virus (EBV) is induced by the EBV oncogene LMP1.
  Journal
J Virol 68:1697-705 (1994)
DOI:10.1128/JVI.68.3.1697-1705.1994
  Sequence
[hsa:814]

DBGET integrated database retrieval system