KEGG   ORTHOLOGY: K06101Help
Entry
K06101                      KO                                     

Name
ASH1L
Definition
histone-lysine N-methyltransferase ASH1L [EC:2.1.1.43]
Pathway
ko00310  Lysine degradation
Disease
H00773  Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    K06101  ASH1L; histone-lysine N-methyltransferase ASH1L
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K06101  ASH1L; histone-lysine N-methyltransferase ASH1L
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     K06101  ASH1L; histone-lysine N-methyltransferase ASH1L
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     K06101  ASH1L; histone-lysine N-methyltransferase ASH1L
BRITE hierarchy
Other DBs
RN: R03875 R03938 R04866 R04867
GO: 0018024
Genes
HSA: 55870(ASH1L)
PTR: 107971434(ASH1L)
PPS: 100979709(ASH1L)
GGO: 101134264(ASH1L)
NLE: 100580011(ASH1L)
MCC: 717778(ASH1L)
MCF: 101867084(ASH1L)
CSAB: 103223879(ASH1L)
RRO: 104659604(ASH1L)
RBB: 108526806(ASH1L)
CJC: 100393607(ASH1L)
SBQ: 101046051(ASH1L)
MMU: 192195(Ash1l)
RNO: 310638(Ash1l)
CGE: 100754103(Ash1l)
NGI: 103750808(Ash1l)
HGL: 101723836(Ash1l)
CCAN: 109688014(Ash1l)
OCU: 100354541(ASH1L)
TUP: 102469443(ASH1L)
CFA: 480128(ASH1L)
AML: 100474237(ASH1L)
UMR: 103668369(ASH1L)
ORO: 101362745(ASH1L)
FCA: 101086114(ASH1L)
PTG: 102969379(ASH1L)
AJU: 106981535(ASH1L)
BTA: 540563(ASH1L)
BOM: 102275046(ASH1L)
BIU: 109553548(ASH1L)
PHD: 102327416(ASH1L)
CHX: 102185413(ASH1L)
OAS: 101119775(ASH1L)
SSC: 100155920(ASH1L)
CDK: 105088782(ASH1L)
BACU: 103015822(ASH1L)
LVE: 103087473(ASH1L)
OOR: 101288541(ASH1L)
ECB: 100057386(ASH1L)
EAI: 106828486(ASH1L)
MYB: 102256394(ASH1L)
MYD: 102764796(ASH1L)
HAI: 109393386(ASH1L)
RSS: 109434286(ASH1L)
PALE: 102888124(ASH1L)
LAV: 100668468(ASH1L)
TMU: 101348724
MDO: 100017118(ASH1L)
SHR: 100931585(ASH1L)
GGA: 425064(ASH1L)
MGP: 100539732(ASH1L)
CJO: 107324503(ASH1L)
APLA: 101794256(ASH1L)
ACYG: 106048498(ASH1L)
TGU: 100229714(ASH1L)
GFR: 102042927(ASH1L)
FAB: 101819907(ASH1L)
PHI: 102113028(ASH1L)
PMAJ: 107214568(ASH1L)
CCW: 104683547(ASH1L)
FPG: 101913546(ASH1L)
FCH: 102056587(ASH1L)
CLV: 102090928(ASH1L)
EGZ: 104134854(ASH1L)
AAM: 106494341(ASH1L)
ASN: 102372997(ASH1L)
AMJ: 102571713(ASH1L)
PSS: 102448117(ASH1L)
CMY: 102943662(ASH1L)
CPIC: 101942050(ASH1L)
ACS: 100563888(ash1l)
PVT: 110081037(ASH1L)
PBI: 103060233(ASH1L)
GJA: 107119617(ASH1L)
NPR: 108794233(ASH1L)
DRE: 563799(ash1l)
IPU: 108267029(ash1l) 108272684
LCO: 104929091 104934663(ash1l)
NCC: 104942643 104958848(ash1l)
OLA: 101156847(ash1l) 101161417
XMA: 102219717 102229525(ash1l)
PRET: 103472762 103478185(ash1l)
NFU: 107379592(ash1l) 107394561
CSEM: 103388251(ash1l) 103394569
LCF: 108885923(ash1l) 108888847
HCQ: 109513128 109521050(ash1l)
BPEC: 110163006(ash1l) 110167402
ELS: 105006914 105024439(ash1l)
SFM: 108925420(ash1l)
LCM: 102367246(ASH1L)
CIN: 778906(Ci-ZF(PHD)-13)
SPU: 579712
APLC: 110987401
SKO: 100373611
DME: Dmel_CG8887(ash1)
DSI: Dsimw501_GD12268(Dsim_GD12268)
MDE: 101901319
AAG: 5572241
AME: 727238
BIM: 100746434
BTER: 100647786
SOC: 105193654
AEC: 105149286
ACEP: 105624295
PBAR: 105427128
HST: 105190078
CFO: 105257554
LHU: 105670382
PGC: 109860146
NVI: 100123305(ash1)
TCA: 660094
DPA: 109540203
NVL: 108559411
BMOR: 101737263
PMAC: 106716351
PRAP: 111004449
PXY: 105391614
API: 100165448
DNX: 107173100
ZNE: 110835718
FCD: 110851509
TUT: 107372226
CEL: CELE_T12F5.4(lin-59)
CBR: CBG12017(Cbr-lin-59)
BMY: Bm1_04930
CRG: 105322748
MYI: 110465579
OBI: 106884485
LAK: 106158443
NCR: NCU01932(set-3)
NTE: NEUTE1DRAFT125465(NEUTE1DRAFT_125465)
MGR: MGG_02937
SSCK: SPSK_05820
NHE: NECHADRAFT_123121(SDG2103)
MAW: MAC_07938
MAJ: MAA_09293
CMT: CCM_06493
MBE: MBM_00593
ANI: AN4764.2
ANG: ANI_1_2518094(An11g09860)
ABE: ARB_07287
TVE: TRV_02019
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
An S, Yeo KJ, Jeon YH, Song JJ
  Title
Crystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanism.
  Journal
J Biol Chem 286:8369-74 (2011)
DOI:10.1074/jbc.M110.203380
  Sequence
[hsa:55870]

DBGET integrated database retrieval system