KEGG   ORTHOLOGY: K06525Help
Entry
K06525                      KO                                     

Name
ITGB4, CD104
Definition
integrin beta 4
Pathway
ko04151  PI3K-Akt signaling pathway
ko04510  Focal adhesion
ko04512  ECM-receptor interaction
ko04810  Regulation of actin cytoskeleton
ko05165  Human papillomavirus infection
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
Disease
H00586  Epidermolysis bullosa, junctional
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K06525  ITGB4, CD104; integrin beta 4
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06525  ITGB4, CD104; integrin beta 4
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K06525  ITGB4, CD104; integrin beta 4
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K06525  ITGB4, CD104; integrin beta 4
 09160 Human Diseases
  09166 Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K06525  ITGB4, CD104; integrin beta 4
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K06525  ITGB4, CD104; integrin beta 4
   05414 Dilated cardiomyopathy (DCM)
    K06525  ITGB4, CD104; integrin beta 4
  09172 Infectious diseases: Viral
   05165 Human papillomavirus infection
    K06525  ITGB4, CD104; integrin beta 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K06525  ITGB4, CD104; integrin beta 4
   04515 Cell adhesion molecules
    K06525  ITGB4, CD104; integrin beta 4
   04090 CD molecules
    K06525  ITGB4, CD104; integrin beta 4
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   K06525  ITGB4, CD104; integrin beta 4
  Exosomal proteins of bladder cancer cells
   K06525  ITGB4, CD104; integrin beta 4
Cell adhesion molecules [BR:ko04515]
 Integrins
  Integrin beta subunits
   K06525  ITGB4, CD104; integrin beta 4
CD molecules [BR:ko04090]
 Proteins
  K06525  CD104, ITGB4; integrin, beta 4
BRITE hierarchy
Genes
HSA: 3691(ITGB4)
PTR: 454887(ITGB4)
PPS: 100986193(ITGB4)
GGO: 101141382(ITGB4) 109026951
PON: 100453768(ITGB4)
NLE: 100606975(ITGB4)
MCC: 703770(ITGB4)
MCF: 102132595(ITGB4)
CSAB: 103243035(ITGB4)
RRO: 104681299(ITGB4)
RBB: 108537357(ITGB4)
CJC: 100398837(ITGB4)
SBQ: 101037393(ITGB4)
MMU: 192897(Itgb4)
RNO: 25724(Itgb4)
CGE: 100756849(Itgb4)
NGI: 103732717(Itgb4)
HGL: 101697313(Itgb4)
CCAN: 109695994(Itgb4)
OCU: 100101587(ITGB4)
TUP: 102488207(ITGB4)
CFA: 483318(ITGB4)
AML: 100469928(ITGB4)
UMR: 103665746(ITGB4)
ORO: 101384197(ITGB4)
FCA: 101080415(ITGB4)
PTG: 102948858(ITGB4)
AJU: 106987780(ITGB4)
BTA: 506995(ITGB4)
BOM: 102288240(ITGB4)
BIU: 109574049(ITGB4)
PHD: 102327436(ITGB4)
CHX: 102191175(ITGB4)
OAS: 101119919(ITGB4)
SSC: 100521988(ITGB4)
CFR: 102513390(ITGB4)
CDK: 105104653(ITGB4)
BACU: 103016174(ITGB4)
LVE: 103077180(ITGB4)
OOR: 101273546(ITGB4)
ECB: 100051679(ITGB4)
EPZ: 103546589(ITGB4)
EAI: 106830304(ITGB4)
MYB: 102260390(ITGB4)
MYD: 102761395(ITGB4)
HAI: 109383761(ITGB4)
RSS: 109454713(ITGB4)
PALE: 102898254(ITGB4)
LAV: 100671877(ITGB4)
TMU: 101357545
MDO: 100027264(ITGB4)
SHR: 100919163(ITGB4)
OAA: 100090852(ITGB4)
GGA: 417374(ITGB4)
MGP: 100544044(ITGB4)
CJO: 107322089(ITGB4)
APLA: 101798901(ITGB4)
ACYG: 106034721(ITGB4)
TGU: 100231330(ITGB4)
SCAN: 103820000(ITGB4)
GFR: 102031672(ITGB4)
FAB: 101809686(ITGB4)
PHI: 102104162(ITGB4)
PMAJ: 107212403(ITGB4)
CCAE: 111937302(ITGB4)
CCW: 104694382(ITGB4)
FPG: 101923093(ITGB4)
FCH: 102049446(ITGB4)
CLV: 102087266(ITGB4)
EGZ: 104125393(ITGB4)
NNI: 104022852(ITGB4)
ACUN: 113486765(ITGB4)
AAM: 106485674(ITGB4)
ASN: 102379093(ITGB4)
AMJ: 102562806(ITGB4)
PSS: 102445383(ITGB4)
CMY: 102937311(ITGB4)
CPIC: 101940932(ITGB4)
ACS: 100556105(itgb4)
PVT: 110085179(ITGB4)
PBI: 103048232(ITGB4)
PMUR: 107290217(ITGB4)
GJA: 107113186(ITGB4)
XLA: 108701118(itgb4.L) 108702819(itgb4.S)
XTR: 100485847(itgb4)
NPR: 108791154(ITGB4)
DRE: 335269(itgb4)
SRX: 107725294 107758026
SANH: 107664990(itgb4) 107700296
SGH: 107557197 107599031
CCAR: 109059019 109085651 109099241
IPU: 108265318(itgb4)
PHYP: 113525460 113525767
AMEX: 103047644(itgb4)
EEE: 113587958(itgb4)
TRU: 101073040(itgb4)
TNG: GSTEN00021715G001
LCO: 104924907(itgb4)
NCC: 104947782 104958720
MZE: 101465287(itgb4)
OLA: 101158429(itgb4)
XMA: 102232649(itgb4)
PRET: 103460961 103482104(itgb4)
NFU: 107388303(itgb4)
KMR: 108235885(itgb4)
CSEM: 103382112(itgb4)
LCF: 108872502(itgb4)
SDU: 111220033(itgb4)
HCQ: 109513294(itgb4)
BPEC: 110155181(itgb4)
MALB: 109974900(itgb4)
SASA: 106578871 106589476(itgb4)
OTW: 112224778 112233642 112237626
SALP: 111968238 112079512 112080649
ELS: 105023024(itgb4)
SFM: 108939918(itgb4)
PKI: 111856701(itgb4)
LCM: 102353222(ITGB4)
CMK: 103175434(itgb4)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2311577
  Authors
Suzuki S, Naitoh Y
  Title
Amino acid sequence of a novel integrin beta 4 subunit and primary expression of the mRNA in epithelial cells.
  Journal
EMBO J 9:757-63 (1990)
  Sequence
[hsa:3691]
Reference
  Authors
Koster J, Geerts D, Favre B, Borradori L, Sonnenberg A
  Title
Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.
  Journal
J Cell Sci 116:387-99 (2003)
DOI:10.1242/jcs.00241

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (16)   
   KEGG PATHWAY (16)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (860)   
   KEGG GENES (134)   
   KEGG MGENES (192)   
   RefGene (531)   
   OC (3)   
Protein sequence (25)   
   UniProt (23)   
   SWISS-PROT (2)   
Literature (2)   
   PubMed (2)   
All databases (908)   

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