KEGG ORTHOLOGY: K06540

ORTHOLOGY: K06540

Entry

K06540                      KO

Symbol

ADAM8, CD156a

Name

disintegrin and metalloproteinase domain-containing protein 8 [EC:3.4.24.-]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K06540  ADAM8, CD156a; disintegrin and metalloproteinase domain-containing protein 8
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06540  ADAM8, CD156a; disintegrin and metalloproteinase domain-containing protein 8
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.-
     K06540  ADAM8, CD156a; disintegrin and metalloproteinase domain-containing protein 8
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
  Family M12: astacin/adamalysin family
   K06540  ADAM8, CD156a; disintegrin and metalloproteinase domain-containing protein 8
CD molecules [BR:ko04090]
Proteins
  K06540  CD156a, ADAM8; a disintegrin and metalloproteinase domain 8

Genes

HSA:	101(ADAM8)

PTR:	747844(ADAM8)

PPS:	100995747(ADAM8)

PON:	100447105(ADAM8)

NLE:	100594764(ADAM8)

HMH:	116481728(ADAM8)

MCC:	100428452(ADAM8)

MCF:	102128894(ADAM8)

MTHB:

126963288

MNI:	105471183(ADAM8)

CSAB:

103245965(ADAM8)

CATY:

105598988(ADAM8)

PANU:

101020025(ADAM8)

TGE:	112631476(ADAM8)

MLEU:

105540300(ADAM8)

RRO:	104677640(ADAM8)

RBB:

108543361

TFN:	117082031(ADAM8)

PTEH:

111522061(ADAM8)

CANG:

105511800(ADAM8)

CJC:	100393217(ADAM8)

SBQ:	101048912(ADAM8)

CIMI:

108297217(ADAM8)

CSYR:

103254660(ADAM8)

MMUR:

105861480(ADAM8)

LCAT:

123650197(ADAM8)

PCOQ:

105823483(ADAM8)

OGA:	100957450(ADAM8)

MMU:	11501(Adam8)

MCAL:

110298146(Adam8)

MPAH:

110322227(Adam8)

RNO:	499285(Adam8)

MCOC:

116103166(Adam8)

ANU:	117698178(Adam8)

MUN:	110549029(Adam8)

CGE:	100770949(Adam8)

MAUA:

101825702(Adam8)

PROB:

127228497(Adam8)

PLEU:

114693252(Adam8)

MORG:

121457747(Adam8)

MFOT:

126498294

AAMP:

119823344(Adam8)

NGI:	103725835(Adam8)

HGL:	101701563(Adam8)

CPOC:

100726804(Adam8)

CCAN:

109690852(Adam8)

DORD:

106000252(Adam8)

DSP:	122127840(Adam8)

PLOP:

125342462(Adam8)

NCAR:

124974922

OCU:

100342070

OPI:	101534201(ADAM8)

TUP:	102484985(ADAM8)

GVR:	103605919(ADAM8)

CFA:	491699(ADAM8)

CLUD:

112672537(ADAM8)

VVP:	112928848(ADAM8)

VLG:	121484223(ADAM8)

NPO:	129523221(ADAM8)

AML:	100471554(ADAM8)

UMR:	103659607(ADAM8)

UAH:	113252090(ADAM8)

UAR:	123800014(ADAM8)

ELK:

111144950

LLV:

125084445

MPUF:

101673967(ADAM8)

NVS:	122899058(ADAM8)

ORO:	101372637(ADAM8)

EJU:	114221779(ADAM8)

ZCA:	113923829(ADAM8)

MLX:	117998003(ADAM8)

NSU:	110592704(ADAM8)

LWW:	102732208(ADAM8)

FCA:	101088880(ADAM8)

PYU:	121037424(ADAM8)

PCOO:

112854721(ADAM8)

PBG:	122493410(ADAM8)

LRUF:

124507250

PTG:	102952796(ADAM8)

PPAD:

109256686(ADAM8)

PUC:

125933069

AJU:

106987499

HHV:	120245376(ADAM8)

BTA:	519652(ADAM8)

BOM:	102282249(ADAM8)

BIU:	109553013(ADAM8)

BBUB:

102393549(ADAM8)

BBIS:

104979714

CHX:	106503654(ADAM8)

OAS:	105605819(ADAM8)

BTAX:

128067846(ADAM8)

ODA:	120873810(ADAM8)

CCAD:

122445805(ADAM8)

MBEZ:

129555229(ADAM8)

SSC:	100156146(ADAM8)

CFR:	102511785(ADAM8)

CBAI:

105067019(ADAM8)

CDK:	105104584(ADAM8) 116147111

VPC:	102544143(ADAM8)

BACU:

103015265(ADAM8)

LVE:	103070000(ADAM8)

OOR:	101285764(ADAM8)

DLE:	111172165(ADAM8)

PCAD:

102979181(ADAM8)

PSIU:

116741826(ADAM8)

NASI:

112411123(ADAM8)

ECB:	111772543(ADAM8)

EPZ:	103554525(ADAM8)

EAI:	106841077(ADAM8)

MYB:	102258664(ADAM8)

MYD:	102762303(ADAM8)

MMYO:

118669664(ADAM8)

MLF:	102432875(ADAM8)

MNA:	107532081(ADAM8)

PKL:	118719549(ADAM8)

EFUS:

103288612(ADAM8)

HAI:	109383561(ADAM8)

DRO:	112300233(ADAM8)

SHON:

118990611(ADAM8)

AJM:	119059488(ADAM8)

PDIC:

114497629(ADAM8)

PHAS:

123829078(ADAM8)

MMF:	118632478(ADAM8)

RFQ:	117035720(ADAM8)

PALE:

102884921(ADAM8)

PGIG:

120581220(ADAM8)

PVP:	105300385(ADAM8)

RAY:	107517155(ADAM8)

MJV:	108395409(ADAM8)

TOD:	119234111(ADAM8)

SARA:

101542703(ADAM8)

LAV:

100669791

TMU:

101360839

ETF:	123521846(ADAM8)

DNM:	101420569(ADAM8)

MDO:

100027023

GAS:	123234397(ADAM8) 123245022

SHR:	100929705(ADAM8)

AFZ:	127540332 127552239

PCW:	110198672(ADAM8)

OAA:	103169085(ADAM8)

GGA:	423672(ADAM8)

PCOC:

116234779(ADAM8)

MGP:	100542325(ADAM8)

CJO:	107315624(ADAM8)

TPAI:

128077875(ADAM8)

LMUT:

125693402(ADAM8)

NMEL:

110390495(ADAM8)

ACYG:

106030115(ADAM8)

CATA:

118247491(ADAM8)

AFUL:

116491275(ADAM8)

TGU:	100218432(ADAM8)

LSR:	110474012(ADAM8)

SCAN:

103814232(ADAM8)

PMOA:

120499709(ADAM8)

OTC:	121336197(ADAM8)

PRUF:

121358088(ADAM8)

GFR:	102041936(ADAM8)

FAB:	101807024(ADAM8)

OMA:	130255160(ADAM8)

PHI:	102110539(ADAM8)

PMAJ:

107206553(ADAM8)

CCAE:

111931627(ADAM8)

CCW:	104695095(ADAM8)

CBRC:

103615284(ADAM8)

ETL:	114067564(ADAM8)

ZAB:

102074989

ACHL:

103808789(ADAM8)

SVG:	106856697(ADAM8)

MMEA:

130582427(ADAM8)

HRT:	120755779(ADAM8)

FPG:	101914591(ADAM8)

FCH:	102053664(ADAM8)

CLV:	102084845(ADAM8)

EGZ:	104125141(ADAM8)

NNI:	104013581(ADAM8)

PCRI:

104038691

PLET:

104625260

EHS:

104513123

PCAO:

104052178(ADAM8)

ACUN:

113481836(ADAM8)

TALA:

104359904(ADAM8)

PADL:

103924296(ADAM8)

AFOR:

103895498(ADAM8)

ACHC:

115348568(ADAM8)

HALD:

104321708

HLE:	104833469(ADAM8)

AGEN:

126043096

GCL:

127017870

CCRI:

104160099(ADAM8)

CMAC:

104484185(ADAM8)

MUI:

104546976

BREG:

104630088(ADAM8)

FGA:

104074618

GSTE:

104257350(ADAM8)

LDI:	104348582(ADAM8)

MNB:	103774922(ADAM8)

OHA:	104330388(ADAM8)

NNT:

104408717

SHAB:

115608050(ADAM8)

PGUU:

104470513

ACAR:

104528772

CPEA:

104397774(ADAM8)

AVIT:

104275698

CVF:	104283544(ADAM8)

CUCA:

104060056(ADAM8)

TEO:	104376443(ADAM8)

AAM:	106495299(ADAM8)

AROW:

112977216(ADAM8)

NPD:	112948448(ADAM8)

TGT:	104567812(ADAM8)

DNE:	112981632(ADAM8)

SCAM:

104149538(ADAM8)

ASN:	102388466(ADAM8)

AMJ:	102566975(ADAM8)

PSS:	102456885(ADAM8)

CMY:	102935296(ADAM8)

CCAY:

125640181(ADAM8)

DCC:	119858629(ADAM8)

CPIC:

101936583(ADAM8)

TST:	117880826(ADAM8)

CABI:

116834401(ADAM8)

MRV:	120368920(ADAM8)

NPR:

108799599

RTEM:

120909098(ADAM8)

MUO:	115471163(ADAM8)

GSH:	117360110(ADAM8)

DRE:	100005593(adam8b) 368917(adam8a)

SRX:	107725440 107739052 107743615 107745666

SANH:

107654071 107666510 107676563 107695548

SGH:	107552911(adam8) 107593516 107596597 107601791

CCAR:

109071042 109100820

CAUA:

113056324 113056987 113079478 113112713

CGIB:

127970397 128024973 128026217

PTET:

122355363(adam8b) 122356947(adam8a)

LROH:

127159133 127174384(adam8b) 127175418(adam8a)

OMC:	131550646(adam8b) 131552757(adam8a)

PPRM:

120464003(adam8b) 120480036(adam8a)

MAMB:

125255501(adam8b) 125276894(adam8a)

CIDE:

127523865 127525352

MASI:

127412070 127414012 127422909 127426737

TROS:

130559041(adam8a) 130568956(adam8b)

IPU:	100303713(adam8a) 108273892(adam8b)

PHYP:

113527100 113543413(adam8)

SMEO:

124378073(adam8a) 124389356(adam8b)

TFD:	113661044(adam8a) 113662690(adam8b)

AMEX:

103037732 103038557(adam8)

CMAO:

118809198(adam8b) 118810706(adam8a)

EEE:	113582067(adam8) 113584617

CHAR:

105891183(adam8b) 105912305(adam8a)

TRU:	101067538 101070109

TFS:	130533661(adam8a) 130538123

TNG:	GSTEN00022282G001 GSTEN00030648G001

LCO:	104928986 104930411

NCC:	104944424 104961340(adam8)

CGOB:

115019939(adam8) 115025034

ELY:	117246658(adam8b) 117248050(adam8a)

EFO:	125880385 125903738(adam8a)

PLEP:

121955002(adam8a) 121958844

SLUC:

116053169(adam8a) 116060935(adam8b)

ECRA:

117937094 117960214(adam8a)

ESP:	116670892 116705359

PFLV:

114548662 114572463(adam8)

GAT:	120819591 120820261(adam8a)

PPUG:

119213057 119214309(adam8a)

AFB:	129091499(adam8b) 129092114(adam8a)

CLUM:

117743736(adam8a) 117748344

MSAM:

119915457(adam8b) 119917308(adam8a)

SCHU:

122868205(adam8b) 122884586(adam8a)

CUD:	121510593(adam8a) 121528152(adam8b)

ALAT:

119010194(adam8b) 119033383(adam8a)

MZE:	101485958 101486136

ONL:	100692057(adam8) 100698412

OAU:	116321247 116322796(adam8a)

OLA:	101166011 101166736

OML:	112154641(adam8b) 112162017(adam8a)

XMA:	102232148 102236421

XCO:	114138126 114152419

XHE:	116713352 116727380

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122823465 122842295(adam8a)

CVG:	107086583 107089515

CTUL:

119782503(adam8b) 119790650(adam8a)

GMU:	124858581(adam8a) 124875578(adam8b)

NFU:	107375577(adam8) 107387480

KMR:	108233991(adam8a) 108250654(adam8b)

ALIM:

106521988(adam8) 106533628

NWH:	119423562(adam8b) 119426559(adam8a)

AOCE:

111567465 111581424(adam8)

MCEP:

125019283(adam8a) 125022934(adam8b)

CSEM:

103387397(adam8) 103398849

POV:	109629841 109644016

SSEN:

122759664 122764410 122782090(adam8a)

HHIP:

117753177 117775621 117775967(adam8a)

HSP:	118100851(adam8b) 118118676(adam8a) 118119145

LCF:	108891113(adam8a) 108892005

SDU:	111220359 111235321(adam8)

SLAL:

111655398 111658181

XGL:	120794463(adam8b) 120796051(adam8a)

HCQ:	109516234(adam8)

SSCV:

125978311

BPEC:

110154218 110157170

MALB:

109961088 109962730

BSPL:

114870836(adam8a)

SASA:

106579287

STRU:

115158916 115201020

OTW:	112223620 112224129

OMY:	110491526 110499148

OGO:	124018028 124047586

ONE:	115106498 115143910

OKI:	109865902 109870523

SALP:

111967646 111978613

SNH:	120029478 120046218

CCLU:

121542713 121547256

ELS:	105006916 105010692(adam8)

SFM:	108933535 108942579

PKI:	111836864 111850379(adam8)

AANG:

118217643(adam8a) 118220777

LOC:	102690734(adam8)

PSPA:

121321841 121326268(adam8a)

ARUT:

117415088 117418001(adam8a)

PSEX:

120541737(adam8a)

LCM:	102362605(ADAM8)

CMK:	103182721(adam8a)

RTP:	109934690(adam8)

CPLA:

122541838(adam8a)

LERI:

129712864(adam8a)

HRJ:

PDAM:

SPIS:

HSY:

SMIN:

v1.2.027877.t1(symbB.v1.2.027877.t1)

» show all

Reference

PMID:9126482

Authors

Yoshiyama K, Higuchi Y, Kataoka M, Matsuura K, Yamamoto S

Title

CD156 (human ADAM8): expression, primary amino acid sequence, and gene location.

Journal

Genomics 41:56-62 (1997)
DOI:10.1006/geno.1997.4607

Sequence

[hsa:101]

Reference

PMID:25336660

Authors

Srinivasan S, Romagnoli M, Bohm A, Sonenshein GE

Title

N-glycosylation regulates ADAM8 processing and activation.

Journal

J Biol Chem 289:33676-88 (2014)
DOI:10.1074/jbc.M114.594242

All links

Ontology (4)   
   KEGG BRITE (4)   
Gene (670)   
   KEGG GENES (444)   
   KEGG MGENES (57)   
   RefGene (164)   
   OC (5)   
Literature (2)   
   PubMed (2)   
All databases (676)   

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