KEGG   ORTHOLOGY: K06551
Entry
K06551                      KO                                     
Symbol
SIRPA_B1_G, CD172
Name
signal-regulatory protein alpha/beta1/gamma
Pathway
map04380  Osteoclast differentiation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K06551  SIRPA_B1_G, CD172; signal-regulatory protein alpha/beta1/gamma
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules
    K06551  SIRPA_B1_G, CD172; signal-regulatory protein alpha/beta1/gamma
   04090 CD molecules
    K06551  SIRPA_B1_G, CD172; signal-regulatory protein alpha/beta1/gamma
Cell adhesion molecules [BR:ko04515]
 Immunoglobulin superfamily
  SIRP family
   K06551  SIRPA_B1_G, CD172; signal-regulatory protein alpha/beta1/gamma
CD molecules [BR:ko04090]
 Proteins
  K06551  CD172a, PTPNS1; protein tyrosine phosphatase, non-receptor type substrate 1
  K06551  CD172b, SIRPB1; signal-regulatory protein beta 1
  K06551  CD172g, SIRPB2; signal-regulatory protein beta 2
Genes
HSA: 10326(SIRPB1) 140885(SIRPA) 55423(SIRPG)
PTR: 458036 458039(SIRPA) 458430 746286(SIRPG)
PPS: 100976751 100990170(SIRPB1) 100991082 100992324(SIRPA)
GGO: 101129558(SIRPG) 101130144(SIRPB1) 101135429(SIRPA)
PON: 100456232(SIRPA) 100458151(SIRPB1) 100458517(SIRPG)
NLE: 100590224(SIRPA) 100594057 100595088 115838025
HMH: 116460976 116461117 116461118(SIRPB1) 116461119(SIRPG) 116461231
MCC: 715912 715954 716034 717432 717811(SIRPA)
MCF: 101926317(SIRPA) 102138723 102141933
MTHB: 126929095 126929097 126929099 126929107 126929108
CATY: 105582175(SIRPA) 105582181(SIRPG) 105582182(SIRPB1) 105582183 105582410
TGE: 112632984(SIRPG) 112632997(SIRPA)
MLEU: 105535290 105535307 105535321(SIRPG) 105536161(SIRPA)
RRO: 104660212(SIRPG) 104674639 104676556(SIRPB1) 104676557
CJC: 100400017(SIRPB1) 100400378
SBQ: 101045331(SIRPB1) 101046281(SIRPA)
CSYR: 103253603(SIRPA) 103262282
LCAT: 123622180(SIRPB1) 123622514
MMU: 100038947(Sirpb1c) 19261(Sirpa) 320832(Sirpb1a) 668101(Sirpb1b) 751864(Sirpd)
RNO: 25528(Sirpa)
PROB: 127221271(Sirpa) 127233070
AAMP: 119809976 119814174(Sirpa)
HGL: 101706086(Sirpa) 101720849(Sirpb1)
CPOC: 100719352 100719630(Sirpa)
GVR: 103593248(SIRPA) 103603268 103603269(SIRPD) 103603270(SIRPB1)
CFA: 485809 609452(SIRPA) 609523
MLX: 118011325(SIRPA) 118011607
PTG: 102955164 102960049(SIRPB1) 102971634(SIRPA)
PPAD: 109274808(SIRPA) 109274814
BTA: 104973826 327666(SIRPA) 529990(SIRPB1) 536097
BBIS: 104986090(SIRPB1) 104986091 104986185(SIRPA)
OAS: 101105677(SIRPA) 101105937
BACU: 103000151 103017280(SIRPA)
LVE: 103083900
OOR: 101284835(SIRPA) 101285095(SIRPB1)
DLE: 111184361 111184363(SIRPA)
PSIU: 116739680(SIRPA) 116739797
NASI: 112398470(SIRPG)
MYD: 102757397(SIRPA) 102759557 102759846 102760711(SIRPB1)
MNA: 107539327(SIRPB1) 107539348(SIRPA) 107544434
PKL: 118708344(SIRPA) 118708347
EFUS: 103285608(SIRPA) 103285827
MMF: 118618252(SIRPA) 118618679
MJV: 108404321
SARA: 101542855(SIRPB1)
SHR: 100914684(SIRPA) 100922951
PCW: 110193727(SIRPA) 110211378
OAA: 114806184
GGA: 419267(SIRPA) 771734(TPPNR1L)
ACYG: 106040831
LSR: 110468975
PMOA: 120506983
OTC: 121331611
FAB: 101819771(SIRPA)
CBRC: 103617661
ZAB: 102063964
MMEA: 130573565
FPG: 101919259(SIRPA) 101919432
FCH: 102053597
EGZ: 104122644
NNI: 104020053
EHS: 104515883
ACUN: 113490612(SIRPA)
TALA: 104366337
PADL: 103919515
AFOR: 103901815
HLE: 104832991(SIRPB1) 104832992(SIRPA)
GCL: 127023322
CCRI: 104162904(SIRPA)
OHA: 104329062
ACAR: 104527285(SIRPA)
CPEA: 104397370
CUCA: 104060885 104060886(SIRPA)
TEO: 104377547
AAM: 106493210
DNE: 112987259
SCAM: 104152607
CPOO: 109318878(SIRPA)
GGN: 109292384(SIRPA)
SUND: 121929286
PTEX: 113434267(SIRPA)
RTEM: 120916000
MUO: 115476560
GSH: 117345742
CMAO: 118799204
LCO: 109143104
NCC: 104945714
CGOB: 115020989
ELY: 117265635
EFO: 125893848
PLEP: 121946280
SLUC: 116060623
ECRA: 117946779
ESP: 116690471
PPUG: 119196968
MSAM: 119897241
SCHU: 122881779
ALAT: 119005469
MZE: 101472668
OAU: 120442724
KMR: 108240327
ALIM: 106523043
XGL: 120783587
SASA: 106582725
STRU: 115177104
OTW: 112246079
OGO: 124004727
OKI: 109903800
SALP: 111959146
ELS: 105027353
AANG: 118236094
CPLA: 122546281 122558631 122558632(si:ch211-137i24.12) 122558648
APLC: 110987854
HAZT: 108670935
HRJ: 124258164
 » show all
Reference
PMID:9070220
  Authors
Yamao T, Matozaki T, Amano K, Matsuda Y, Takahashi N, Ochi F, Fujioka Y, Kasuga M
  Title
Mouse and human SHPS-1: molecular cloning of cDNAs and chromosomal localization of genes.
  Journal
Biochem Biophys Res Commun 231:61-7 (1997)
DOI:10.1006/bbrc.1996.6047
  Sequence
[hsa:140885]
Reference
  Authors
Barclay AN, Brown MH
  Title
The SIRP family of receptors and immune regulation.
  Journal
Nat Rev Immunol 6:457-64 (2006)
DOI:10.1038/nri1859

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