KEGG ORTHOLOGY: K06619

ORTHOLOGY: K06619

Entry

K06619 KO

Name

ABL1

Definition

abelson tyrosine-protein kinase 1 [EC:2.7.10.2]

Pathway

ko04012

ErbB signaling pathway

ko04014

Ras signaling pathway

ko04110

Cell cycle

ko04360

Axon guidance

ko04722

Neurotrophin signaling pathway

ko05130

Pathogenic Escherichia coli infection

ko05200

Pathways in cancer

ko05206

MicroRNAs in cancer

ko05220

Chronic myeloid leukemia

ko05416

Viral myocarditis

Disease

H00001

B-cell acute lymphoblastic leukemia

H00004

Chronic myeloid leukemia

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K06619  ABL1; abelson tyrosine-protein kinase 1
   04014 Ras signaling pathway
    K06619  ABL1; abelson tyrosine-protein kinase 1
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K06619  ABL1; abelson tyrosine-protein kinase 1
09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K06619  ABL1; abelson tyrosine-protein kinase 1
  09158 Development and regeneration
   04360 Axon guidance
    K06619  ABL1; abelson tyrosine-protein kinase 1
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K06619  ABL1; abelson tyrosine-protein kinase 1
   05206 MicroRNAs in cancer
    K06619  ABL1; abelson tyrosine-protein kinase 1
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    K06619  ABL1; abelson tyrosine-protein kinase 1
  09166 Cardiovascular disease
   05416 Viral myocarditis
    K06619  ABL1; abelson tyrosine-protein kinase 1
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K06619  ABL1; abelson tyrosine-protein kinase 1
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K06619  ABL1; abelson tyrosine-protein kinase 1
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K06619  ABL1; abelson tyrosine-protein kinase 1
Protein kinases [BR:ko01001]
Non-receptor tyrosine kinases
  ABL family
   K06619  ABL1; abelson tyrosine-protein kinase 1

Other DBs

GO:

0004715

Genes

HSA:

25(ABL1)

PTR:	107976801(ABL1)

PPS:	100994981(ABL1)

GGO:	101127165(ABL1)

PON:	100453216(ABL1)

NLE:	100601002(ABL1)

MCC:	722449(ABL1)

MCF:	102115803(ABL1)

CSAB:

103239742(ABL1)

RRO:	104660552(ABL1)

RBB:	108513941(ABL1)

CJC:	100398414(ABL1)

SBQ:	101046557(ABL1)

MMU:	11350(Abl1)

MCAL:

110289525(Abl1)

MPAH:

110318646(Abl1)

RNO:	100909750 311860(Abl1)

MUN:	110558915(Abl1)

CGE:	100768098(Abl1)

NGI:	103727721(Abl1)

HGL:	101724428(Abl1)

CCAN:

109700215(Abl1)

OCU:	100345909(ABL1)

TUP:	102470554(ABL1)

CFA:	491292(ABL1)

VVP:	112927987(ABL1)

AML:	100466468(ABL1)

UMR:	103670413(ABL1)

UAH:	113266525(ABL1)

ORO:	101370651(ABL1)

ELK:

111146116

FCA:	101087622(ABL1)

PTG:	102949569(ABL1)

PPAD:

109250012(ABL1)

AJU:	106985340(ABL1)

BTA:	540876(ABL1)

BOM:	102266301(ABL1)

BIU:	109566554(ABL1)

BBUB:

102401862(ABL1)

CHX:	102184349(ABL1)

OAS:	101122941(ABL1)

SSC:	100524544(ABL1)

CFR:	102519310(ABL1)

CDK:	105092528(ABL1)

BACU:

102998508(ABL1)

LVE:	103076172(ABL1)

OOR:	101281151(ABL1)

DLE:	111177117(ABL1)

PCAD:

102988541(ABL1)

ECB:	100069715(ABL1)

EPZ:	103562771(ABL1)

EAI:	106845390(ABL1)

MYB:	102255271(ABL1)

MYD:	102757649(ABL1)

MNA:	107524646(ABL1)

HAI:	109380669(ABL1)

DRO:	112306226(ABL1)

PALE:

102895947(ABL1)

RAY:	107504550(ABL1)

MJV:	108408195(ABL1)

LAV:	100677152(ABL1)

TMU:

101341732

MDO:	100619549(ABL1)

SHR:	100930047(ABL1)

PCW:	110198907(ABL1)

OAA:	100075676(ABL1)

GGA:	417181(ABL1)

MGP:	100550407(ABL1)

CJO:	107321848(ABL1)

NMEL:

110406778(ABL1)

APLA:

101794358(ABL1)

ACYG:

106044113(ABL1)

TGU:	100223450(ABL1)

LSR:	110477593(ABL1)

SCAN:

103818997(ABL1)

GFR:	102042232(ABL1)

FAB:	101817037(ABL1)

PHI:	102099348(ABL1)

PMAJ:

107212136(ABL1)

CCAE:

111937004(ABL1)

CCW:	104688306(ABL1)

ETL:	114073812(ABL1)

FPG:	101918950(ABL1)

FCH:	102052443(ABL1)

CLV:	102086741(ABL1)

EGZ:	104129817(ABL1)

NNI:	104023169(ABL1)

ACUN:

113486462(ABL1)

PADL:

103915284(ABL1)

AAM:	106486072(ABL1)

ASN:	102368526(ABL1)

AMJ:	102564337(ABL1)

PSS:	102455334(ABL1)

CMY:	102943857(ABL1)

CPIC:

101935179(ABL1)

ACS:	100557530(abl1)

PVT:	110079629(ABL1)

PBI:

103059276

PMUR:

107291344(ABL1)

TSR:	106554736(ABL1)

PMUA:

114589465(ABL1)

GJA:	107108928(ABL1)

XLA:	108699954(abl1.S) 108704697(abl1.L)

XTR:	100490771(abl1)

NPR:	108788711(ABL1)

DRE:	100000720(abl1)

SRX:	107729293 107745339(abl1)

SANH:

107670387 107674916

SGH:	107566858 107577903 107597931

CCAR:

109048738(abl1) 109057589

IPU:	108259985(abl1)

PHYP:

113531133(abl1)

AMEX:

103046185(abl1)

EEE:

113583945

TRU:	101064177(abl1)

TNG:	GSTEN00017201G001

LCO:	104924853(abl1)

NCC:	104956356(abl1)

MZE:	101475377(abl1)

ONL:	100709901(abl1)

OLA:	101155287(abl1)

XMA:	102230386(abl1)

XCO:	114149479(abl1)

PRET:

103473791(abl1)

CVG:	107088442(abl1)

NFU:	107374064(abl1)

KMR:	108230984(abl1)

ALIM:

106532564(abl1)

AOCE:

111578179(abl1)

CSEM:

103390173(abl1)

POV:

109626307

LCF:	108888951(abl1)

SDU:	111237780(abl1)

SLAL:

111664729(abl1)

HCQ:

109514691

BPEC:

110160463(abl1)

MALB:

109960591

SASA:

106563284 106566947

OTW:	112219306 112230988

SALP:

111961611 111964018

ELS:	105015016(abl1)

SFM:	108922661 108938597

PKI:	111842668 111843474

LCM:	102355014(ABL1)

CMK:	103183028(abl1)

RTP:

BFO:

CIN:

SPU:

APLC:

SKO:	100374571(ABL2)

DME:	Dmel_CG4032(Abl)

DER:

6544214

DSE:

6605990

DYA:	Dyak_GE22200

DAN:

6493382

DSR:

110183566

DPO:	Dpse_GA17894

DPE:

6601926

DMN:

108152128

DWI:

6643100

DGR:	Dgri_GH16452

DMO:	Dmoj_GI16710

DAZ:

DNV:

DHE:

DVI:

MDE:

LCQ:

AGA:	AgaP_AGAP004989

AAG:

5571049

AALB:

109408571 109423868

CQU:	CpipJ_CPIJ003985 CpipJ_CPIJ009602

AME:

BIM:

BTER:

CCAL:

OBB:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

LHU:

PGC:

OBO:

PCF:

NVI:

CSOL:

MDL:

TCA:

DPA:

ATD:

NVL:

BMOR:

BMAN:

DPL:	KGM_200085

PMAC:

PRAP:

HAW:

PXY:

API:

DNX:

AGS:

RMD:

BTAB:

CLEC:

PHU:	Phum_PHUM538010

ZNE:

110828785

FCD:

110845965

PVM:

113812175

ISC:	IscW_ISCW000295

TUT:

DPTE:

CSCU:

PTEP:

CEL:	CELE_M79.1(abl-1)

CBR:	CBG04507(Cbr-abl-1)

BMY:

Bm1_30590

LOA:	LOAG_05868

NAI:	NECAME_06130

TSP:

Tsp_09251

HRO:	HELRODRAFT_166124

PCAN:

CRG:

MYI:

OBI:

LAK:

SMM:	Smp_128790 Smp_169230

SHX:

MS3_02851

OVI:	T265_05581 T265_08093

EGL:

NVE:

EPA:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

HMG:

AQU:

MNG:

TVS:	TRAVEDRAFT_171082

HIR:	HETIRDRAFT_124459

FME:	FOMMEDRAFT_17451

CCI:	CC1G_13961

MBR:	MONBRDRAFT_44322

SRE:	PTSG_06415 PTSG_08747

ACAN:

ACA1_065920 ACA1_307790

VG:	1491873(gag-abl)

» show all

Reference

PMID:20841568

Authors

Colicelli J

Title

ABL tyrosine kinases: evolution of function, regulation, and specificity.

Journal

Sci Signal 3:re6 (2010)
DOI:10.1126/scisignal.3139re6

Sequence

[hsa:25]

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