KEGG   ORTHOLOGY: K06827
Entry
K06827                      KO                                     

Name
CTGF, CCN2, IGFBP8
Definition
connective tissue growth factor (insulin-like growth factor-binding protein 8)
Pathway
ko04371  Apelin signaling pathway
ko04390  Hippo signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    K06827  CTGF, CCN2, IGFBP8; connective tissue growth factor (insulin-like growth factor-binding protein 8)
   04371 Apelin signaling pathway
    K06827  CTGF, CCN2, IGFBP8; connective tissue growth factor (insulin-like growth factor-binding protein 8)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K06827  CTGF, CCN2, IGFBP8; connective tissue growth factor (insulin-like growth factor-binding protein 8)
Membrane trafficking [BR:ko04131]
 Endocytosis
  Others
   Insulin-like growth factor-binding proteins
    K06827  CTGF, CCN2, IGFBP8; connective tissue growth factor (insulin-like growth factor-binding protein 8)
Other DBs
GO: 0005520 0005178 0008201
Genes
HSA: 1490(CCN2)
PTR: 463003(CTGF)
PPS: 100989664(CTGF)
GGO: 101152280(CCN2)
PON: 100437145(CTGF)
NLE: 100604830(CCN2)
MCC: 714520(CCN2)
MCF: 101926338(CTGF)
CSAB: 103240368(CTGF)
RRO: 104657742(CCN2)
RBB: 108515696(CTGF)
CJC: 100412819(CTGF)
SBQ: 101030328(CTGF)
MMU: 14219(Ccn2)
MCAL: 110303217(Ctgf)
MPAH: 110338078(Ctgf)
RNO: 64032(Ccn2)
MUN: 110539864(Ctgf)
CGE: 100750810(Ccn2)
NGI: 103724962(Ctgf)
HGL: 101706835(Ctgf)
CCAN: 109684563(Ctgf)
OCU: 100008638(CTGF)
TUP: 102486536(CTGF)
CFA: 476202(CTGF)
VVP: 112912250(CTGF)
AML: 100466591(CCN2)
UMR: 103663504(CTGF)
UAH: 113259451(CTGF)
ORO: 101372576(CTGF)
ELK: 111147581
FCA: 101094598(CTGF)
PTG: 102948975(CTGF)
PPAD: 109249925(CTGF)
AJU: 106976853(CCN2)
BTA: 281103(CTGF)
BOM: 102287187(CTGF)
BIU: 109563950(CTGF)
BBUB: 102389862(CCN2)
CHX: 102191048(CTGF)
OAS: 100303607(CCN2)
SSC: 100152141(CTGF)
CFR: 102508035(CCN2)
CDK: 105096376(CCN2)
BACU: 103008494(CTGF)
LVE: 103081232(CTGF)
OOR: 101286151(CTGF)
DLE: 111165772(CCN2)
PCAD: 102991433(CCN2)
ECB: 100073098(CTGF)
EPZ: 103563097(CTGF)
EAI: 106823305(CTGF)
MYB: 102254451(CTGF)
MYD: 102772374(CTGF)
MNA: 107530932(CTGF)
HAI: 109393834(CTGF)
DRO: 112297254(CTGF)
PALE: 102898900(CTGF)
RAY: 107502316(CTGF)
MJV: 108398564(CTGF)
LAV: 100675144(CTGF)
TMU: 101354381
MDO: 100031049(CTGF)
SHR: 100926574(CCN2)
PCW: 110208879(CTGF)
OAA: 100074427(CCN2)
GGA: 374135(CTGF) 776271(CTGFL)
MGP: 100543969(CCN2) 100550412
CJO: 107311757(CCN2) 107323923
NMEL: 110387500 110396712(CTGF)
APLA: 101790193(CCN2) 101805421
ACYG: 106032415(CTGF) 106045149
TGU: 100219910 100224713(CCN2)
LSR: 110476014(CCN2)
SCAN: 103820608(CCN2)
GFR: 102037450 102041470(CTGF)
FAB: 101806743(CTGF) 101813857
PHI: 102099928(CTGF) 102113954
PMAJ: 107202594(CTGF) 107214110
CCAE: 111927707(CTGF)
CCW: 104693962(CCN2) 104697709
ETL: 114064429(CCN2) 114069773
FPG: 101914229 101922395(CTGF)
FCH: 102054023(CCN2) 102059383
CLV: 102092560(CTGF) 102097234
EGZ: 104131212(CTGF) 104132561
NNI: 104008836(CTGF) 104017922
ACUN: 113478306(CCN2) 113488385
PADL: 103912688(CTGF) 103915444
AAM: 106498044(CTGF) 106499882
ASN: 102371210 102379948(CTGF)
AMJ: 102559952(CTGF) 102577158(CTGFB)
PSS: 102444334 102447593(CTGF)
CMY: 102937739 102940830(CCN2)
CPIC: 101931992(CTGF) 101940791
ACS: 100562863(ctgf) 100563442
PVT: 110071989(CTGF) 110082286
PBI: 103048238(CTGF) 103068111
PMUR: 107302643(CCN2) 107303002
TSR: 106537580 106540699(CTGF)
PMUA: 114594149(CCN2) 114603633
GJA: 107108687 107118874(CTGF)
XLA: 108704892 398003(ctgf.L)
XTR: 548598(ccn2)
NPR: 108796229(CTGF)
DRE: 100124530(ccn2b) 321449(ccn2a)
IPU: 108256926(ctgf)
PHYP: 113529257(ccn2)
AMEX: 103034824(ctgf) 103041886
EEE: 113584020 113589763(ccn2)
TRU: 101065539(ccn2)
LCO: 104927386(ccn2)
NCC: 104966068(ctgf)
MZE: 101466391(ctgf)
ONL: 100693059(ctgf)
OLA: 101163784(ctgf)
XMA: 102235918(ctgf)
XCO: 114158412(ccn2)
PRET: 103457939(ctgf)
CVG: 107088487(ctgf)
NFU: 107377994(ctgf)
KMR: 108231725(ccn2a)
ALIM: 106533841(ctgf)
CSEM: 103380752(ctgf) 103394509
POV: 109631602 109632614(ctgf)
SLAL: 111668783 111672745(ctgf)
HCQ: 109509624(ctgf) 109527173
BPEC: 110155053(ctgf)
MALB: 109962147(ctgf)
ELS: 105012325 105017908(ccn2)
SFM: 108923656 108929293(ccn2)
PKI: 111843028(ctgf) 111851115
LCM: 102363650(CTGF) 102365602
CMK: 103179499 103182284(ctgf) 103190703(wisp2)
BFO: 118421279
SKO: 102800596
DER: 6546284
DSR: 110185267
DMN: 108152403
BTAB: 109039694
ZNE: 110841013
PTEP: 107453706
 » show all
Reference
PMID:1654338
  Authors
Bradham DM, Igarashi A, Potter RL, Grotendorst GR
  Title
Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10.
  Journal
J Cell Biol 114:1285-94 (1991)
DOI:10.1083/jcb.114.6.1285
  Sequence
[hsa:1490]
Reference
  Authors
de Winter P, Leoni P, Abraham D
  Title
Connective tissue growth factor: structure-function relationships of a mosaic, multifunctional protein.
  Journal
Growth Factors 26:80-91 (2008)
DOI:10.1080/08977190802025602

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