KEGG ORTHOLOGY: K06835

ORTHOLOGY: K06835

Entry

K06835                      KO

Symbol

ADAM12

Name

disintegrin and metalloproteinase domain-containing protein 12 [EC:3.4.24.-]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K06835  ADAM12; disintegrin and metalloproteinase domain-containing protein 12
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.-
     K06835  ADAM12; disintegrin and metalloproteinase domain-containing protein 12
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
  Family M12: astacin/adamalysin family
   K06835  ADAM12; disintegrin and metalloproteinase domain-containing protein 12

Genes

HSA:	8038(ADAM12)

PTR:	450818(ADAM12)

PPS:	100972590(ADAM12)

GGO:	101150881(ADAM12)

PON:	100459187(ADAM12)

NLE:	100599775(ADAM12)

MCC:	696405(ADAM12)

MCF:	102127463(ADAM12)

CSAB:

103216685(ADAM12)

CATY:

105578036(ADAM12)

PANU:

100999481(ADAM12)

TGE:	112631925(ADAM12)

RRO:	104657949(ADAM12)

RBB:	108519536(ADAM12)

TFN:	117064970(ADAM12)

PTEH:

111550825(ADAM12)

CJC:	100408456(ADAM12)

CSYR:

103260342(ADAM12)

MMUR:

105880374(ADAM12)

OGA:	100963435(ADAM12)

MMU:	11489(Adam12)

MCAL:

110298577(Adam12)

MPAH:

110319315(Adam12)

RNO:	679837(Adam12)

MCOC:

116103125(Adam12)

MUN:	110561224(Adam12)

CGE:	100759770(Adam12)

PLEU:

114692854(Adam12)

HGL:	101701778(Adam12)

CPOC:

100735152(Adam12)

CCAN:

109678450(Adam12)

DORD:

105989787(Adam12)

DSP:	122126883(Adam12)

NCAR:

124985916

OCU:	100341644(ADAM12)

OPI:	101517547(ADAM12)

TUP:	102493064(ADAM12)

CFA:	100686018(ADAM12)

VVP:	112928806(ADAM12)

VLG:	121485349(ADAM12)

AML:	100467556(ADAM12)

UMR:	103659499(ADAM12)

UAH:	113252043(ADAM12)

UAR:	123800055(ADAM12)

ELK:

111145085

LLV:

125084971

MPUF:

101686354(ADAM12)

ORO:	101367760(ADAM12)

EJU:	114221802(ADAM12)

ZCA:	113923503(ADAM12)

MLX:	117997678(ADAM12)

FCA:	101081333(ADAM12)

PYU:	121037486(ADAM12)

PBG:	122493366(ADAM12)

PTG:	102972451(ADAM12)

PPAD:

109252246(ADAM12)

AJU:	106987536(ADAM12)

HHV:	120235529(ADAM12)

BTA:	407229(ADAM12)

BOM:	102272774(ADAM12)

BIU:	109553087(ADAM12)

BBUB:

102408315(ADAM12)

CHX:	102182472(ADAM12)

OAS:	101106128(ADAM12)

ODA:	120873633(ADAM12)

CCAD:

122445822(ADAM12)

SSC:	100157228(ADAM12)

CFR:	102523687(ADAM12)

CBAI:

105067573(ADAM12)

CDK:	105100290(ADAM12)

VPC:	102540154(ADAM12)

BACU:

103011030(ADAM12)

LVE:	103069893(ADAM12)

OOR:	101283306(ADAM12)

DLE:	111172199(ADAM12)

PCAD:

102991696(ADAM12)

PSIU:

116741177(ADAM12)

ECB:	100056196(ADAM12)

EPZ:	103554730(ADAM12)

EAI:	106825347(ADAM12)

MMYO:

118670290(ADAM12)

MNA:	107535160(ADAM12)

PKL:	118719047(ADAM12)

HAI:	109389026(ADAM12)

DRO:	112300427(ADAM12)

SHON:

118990604(ADAM12)

AJM:	119059493(ADAM12)

PDIC:

114497026(ADAM12)

PHAS:

123828900(ADAM12)

MMF:	118632674(ADAM12)

RFQ:	117036387(ADAM12)

PALE:

102889658(ADAM12)

PGIG:

120581264

PVP:	105295704(ADAM12)

RAY:	107512569(ADAM12)

MJV:	108407388(ADAM12)

TOD:	119233620(ADAM12)

SARA:

101550105(ADAM12)

LAV:	100662977(ADAM12)

TMU:

101356720

DNM:	101446257(ADAM12)

MDO:	100013486(ADAM12)

GAS:	123234451(ADAM12)

SHR:	100914499(ADAM12)

PCW:	110198988(ADAM12)

OAA:	100680555(ADAM12)

GGA:	425843(ADAM12)

PCOC:

116231529(ADAM12)

MGP:	100544450(ADAM12)

CJO:	107316293(ADAM12)

NMEL:

110399677(ADAM12)

APLA:

101802680(ADAM12)

ACYG:

106038996(ADAM12)

AFUL:

116491226(ADAM12)

TGU:	100225378(ADAM12)

LSR:	110468419(ADAM12)

SCAN:

103814095(ADAM12)

PMOA:

120512768(ADAM12)

OTC:	121341758(ADAM12)

PRUF:

121350089(ADAM12)

GFR:	102045475(ADAM12)

FAB:	101812960(ADAM12)

PHI:	102102207(ADAM12)

PMAJ:

107207108(ADAM12)

CCAE:

111931408(ADAM12)

CCW:	104694940(ADAM12)

ETL:	114067544(ADAM12)

ZAB:	102064373(ADAM12)

FPG:	101923054(ADAM12)

FCH:	102048424(ADAM12)

CLV:	102098774(ADAM12)

EGZ:	104122704(ADAM12)

NNI:	104022079(ADAM12)

ACUN:

113481770(ADAM12)

TALA:

104366831(ADAM12)

PADL:

103918524(ADAM12)

ACHC:

115348389(ADAM12)

AAM:	106486368(ADAM12)

AROW:

112966034(ADAM12)

NPD:	112949974(ADAM12)

DNE:	112992690(ADAM12)

ASN:	102375297(ADAM12)

AMJ:	102558888(ADAM12)

CPOO:

109323991(ADAM12)

GGN:	109287705(ADAM12)

PSS:	102452843(ADAM12)

CMY:	102933922(ADAM12)

CPIC:

101934003(ADAM12)

TST:	117880013(ADAM12)

CABI:

116833351(ADAM12)

MRV:	120409193(ADAM12)

ACS:	100561819(adam12)

PVT:	110077927(ADAM12)

SUND:

121926598(ADAM12)

PGUT:

117676723(ADAM12)

VKO:	123031102(ADAM12)

PMUA:

114597386(ADAM12)

ZVI:	118096180(ADAM12)

STOW:

125437774(ADAM12)

XLA:	108696121(adam12.L) 108697349 108697394(adam12.S) 108704093

XTR:	677729(adam12)

NPR:	108788859(ADAM12)

RTEM:

120924592(ADAM33) 120946752(ADAM12)

BBUF:

121005169(ADAM12)

BGAR:

122941397(ADAM12)

DRE:	563275(adam12)

SRX:	107733079 107752796

SANH:

107667813 107674032 107697763

SGH:	107549328 107567806 107592760

CCAR:

109077226 109078907 109097630 109107040

CAUA:

113055846 113060621 113078189 113079907 113081088 113095305 113112136 113112144

PPRM:

120462765 120476966(adam12b)

MAMB:

125269063(adam12b)

IPU:	108270250 108273823

PHYP:

113527774 113538782

SMEO:

124388964 124390010

TFD:	113634087 113659728(adam12b)

AMEX:

103042729(adam12)

EEE:

113576647

TRU:	101063861 101073949

TNG:	GSTEN00024968G001

LCO:	104929726 104934654

NCC:	104959042 104964489

CGOB:

115020290 115025127

ELY:	117246697 117247957(adam12)

PLEP:

121954728(adam12b) 121959295

SLUC:

116055504(adam12) 116061077

ECRA:

117937024 117960145(adam12)

PFLV:

114548698 114572305

GAT:	120819851 120820881(adam12b)

PPUG:

119212506 119214358(adam12)

MSAM:

119916298 119917348(adam12b)

CUD:	121511333(adam12b) 121528821

MZE:	101465489 101478677

ONL:	100698394 100703495

OAU:	116322224(adam12b) 116328806

OLA:	101155152(adam12) 101169556

OML:	112154517 112162267(adam12)

XMA:	102228824(adam12) 102229297

XCO:	114138492 114151950

XHE:	116713323 116726960

PRET:

103476761 103481565

PFOR:

103133563(adam12) 103153024 103153033

PLAI:

106949739(adam12)

PMEI:

106919503 106929851(adam12)

GAF:	122823792 122842681(adam12b)

CVG:

107093568

CTUL:

119781928 119783725(adam12b)

GMU:	124858575(adam12b) 124875228

NFU:	107375991(adam12) 107387781

KMR:	108245604(adam12b) 108246095

ALIM:

106513219 106516607(adam12)

NWH:	119423519 119430189(adam12b)

AOCE:

111569408

CSEM:

103381641(adam12) 103387673

POV:	109627143 109630857

SSEN:

122758868 122782068(adam12b)

HHIP:

117752663 117775580(adam12)

LCF:	108897339 108899048

SDU:	111220075 111235168

SLAL:

111655207 111663757

XGL:	120794095 120796913(adam12b)

HCQ:	109510088 109513378

BPEC:

110156976 110163799

MALB:

109962554 109962933

SASA:

106577034(adam12) 106607406

OTW:	112239180 112253063 112254711

OMY:	110502489(adam12) 110510837 110517068 110529328

OGO:	124038267 124041230

ONE:	115113208 115135075(adam12)

SALP:

111952061(adam12) 111978661

SNH:	120017790 120045895

ELS:	105009603 105010575

SFM:	108932900(adam12)

PKI:

111859260

AANG:

118217673 118220611

LOC:	102693085(adam12) 107076975

PSPA:

121321741 121325867

ARUT:

117414663 117417977

CMK:	103185464(adam12b)

BFO:	118412901 118412902

CIN:

SCLV:

ACOZ:

AARA:

NVE:

XEN:	124443828 124444823

TAD:	TRIADDRAFT_1282

AQU:

100635557

» show all

Reference

PMID:9417060

Authors

Gilpin BJ, Loechel F, Mattei MG, Engvall E, Albrechtsen R, Wewer UM

Title

A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo.

Journal

J Biol Chem 273:157-66 (1998)
DOI:10.1074/jbc.273.1.157

Sequence

[hsa:8038]

Reference

PMID:20849079

Authors

Klein T, Bischoff R

Title

Active metalloproteases of the A Disintegrin and Metalloprotease (ADAM) family: biological function and structure.

Journal

J Proteome Res 10:17-33 (2011)
DOI:10.1021/pr100556z

All links

Ontology (3)   
   KEGG BRITE (3)   
Gene (1105)   
   KEGG GENES (333)   
   KEGG MGENES (149)   
   RefGene (617)   
   OC (6)   
Literature (2)   
   PubMed (2)   
All databases (1110)   

Download RDF

DBGET integrated database retrieval system