K06835                      KO                                     
disintegrin and metalloproteinase domain-containing protein 12 [EC:3.4.24.-]
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K06835  ADAM12; disintegrin and metalloproteinase domain-containing protein 12
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
     K06835  ADAM12; disintegrin and metalloproteinase domain-containing protein 12
Peptidases and inhibitors [BR:ko01002]
 Metallo peptidases
  Family M12: astacin/adamalysin family
   K06835  ADAM12; disintegrin and metalloproteinase domain-containing protein 12
HSA: 8038(ADAM12)
PTR: 450818(ADAM12)
PPS: 100972590(ADAM12)
GGO: 101150881(ADAM12)
PON: 100459187(ADAM12)
NLE: 100599775(ADAM12)
MCC: 696405(ADAM12)
MCF: 102127463(ADAM12)
CSAB: 103216685(ADAM12)
CATY: 105578036(ADAM12)
PANU: 100999481(ADAM12)
TGE: 112631925(ADAM12)
RRO: 104657949(ADAM12)
RBB: 108519536(ADAM12)
TFN: 117064970(ADAM12)
PTEH: 111550825(ADAM12)
CJC: 100408456(ADAM12)
CSYR: 103260342(ADAM12)
MMUR: 105880374(ADAM12)
OGA: 100963435(ADAM12)
MMU: 11489(Adam12)
MCAL: 110298577(Adam12)
MPAH: 110319315(Adam12)
RNO: 679837(Adam12)
MCOC: 116103125(Adam12)
MUN: 110561224(Adam12)
CGE: 100759770(Adam12)
PLEU: 114692854(Adam12)
HGL: 101701778(Adam12)
CPOC: 100735152(Adam12)
CCAN: 109678450(Adam12)
DORD: 105989787(Adam12)
DSP: 122126883(Adam12)
NCAR: 124985916
OCU: 100341644(ADAM12)
OPI: 101517547(ADAM12)
TUP: 102493064(ADAM12)
CFA: 100686018(ADAM12)
VVP: 112928806(ADAM12)
VLG: 121485349(ADAM12)
AML: 100467556(ADAM12)
UMR: 103659499(ADAM12)
UAH: 113252043(ADAM12)
UAR: 123800055(ADAM12)
ELK: 111145085
LLV: 125084971
MPUF: 101686354(ADAM12)
ORO: 101367760(ADAM12)
EJU: 114221802(ADAM12)
ZCA: 113923503(ADAM12)
MLX: 117997678(ADAM12)
FCA: 101081333(ADAM12)
PYU: 121037486(ADAM12)
PBG: 122493366(ADAM12)
PTG: 102972451(ADAM12)
PPAD: 109252246(ADAM12)
AJU: 106987536(ADAM12)
HHV: 120235529(ADAM12)
BTA: 407229(ADAM12)
BOM: 102272774(ADAM12)
BIU: 109553087(ADAM12)
BBUB: 102408315(ADAM12)
CHX: 102182472(ADAM12)
OAS: 101106128(ADAM12)
ODA: 120873633(ADAM12)
CCAD: 122445822(ADAM12)
SSC: 100157228(ADAM12)
CFR: 102523687(ADAM12)
CBAI: 105067573(ADAM12)
CDK: 105100290(ADAM12)
VPC: 102540154(ADAM12)
BACU: 103011030(ADAM12)
LVE: 103069893(ADAM12)
OOR: 101283306(ADAM12)
DLE: 111172199(ADAM12)
PCAD: 102991696(ADAM12)
PSIU: 116741177(ADAM12)
ECB: 100056196(ADAM12)
EPZ: 103554730(ADAM12)
EAI: 106825347(ADAM12)
MMYO: 118670290(ADAM12)
MNA: 107535160(ADAM12)
PKL: 118719047(ADAM12)
HAI: 109389026(ADAM12)
DRO: 112300427(ADAM12)
SHON: 118990604(ADAM12)
AJM: 119059493(ADAM12)
PDIC: 114497026(ADAM12)
PHAS: 123828900(ADAM12)
MMF: 118632674(ADAM12)
RFQ: 117036387(ADAM12)
PALE: 102889658(ADAM12)
PGIG: 120581264
PVP: 105295704(ADAM12)
RAY: 107512569(ADAM12)
MJV: 108407388(ADAM12)
TOD: 119233620(ADAM12)
SARA: 101550105(ADAM12)
LAV: 100662977(ADAM12)
TMU: 101356720
DNM: 101446257(ADAM12)
MDO: 100013486(ADAM12)
GAS: 123234451(ADAM12)
SHR: 100914499(ADAM12)
PCW: 110198988(ADAM12)
OAA: 100680555(ADAM12)
GGA: 425843(ADAM12)
PCOC: 116231529(ADAM12)
MGP: 100544450(ADAM12)
CJO: 107316293(ADAM12)
NMEL: 110399677(ADAM12)
APLA: 101802680(ADAM12)
ACYG: 106038996(ADAM12)
AFUL: 116491226(ADAM12)
TGU: 100225378(ADAM12)
LSR: 110468419(ADAM12)
SCAN: 103814095(ADAM12)
PMOA: 120512768(ADAM12)
OTC: 121341758(ADAM12)
PRUF: 121350089(ADAM12)
GFR: 102045475(ADAM12)
FAB: 101812960(ADAM12)
PHI: 102102207(ADAM12)
PMAJ: 107207108(ADAM12)
CCAE: 111931408(ADAM12)
CCW: 104694940(ADAM12)
ETL: 114067544(ADAM12)
ZAB: 102064373(ADAM12)
FPG: 101923054(ADAM12)
FCH: 102048424(ADAM12)
CLV: 102098774(ADAM12)
EGZ: 104122704(ADAM12)
NNI: 104022079(ADAM12)
ACUN: 113481770(ADAM12)
TALA: 104366831(ADAM12)
PADL: 103918524(ADAM12)
ACHC: 115348389(ADAM12)
AAM: 106486368(ADAM12)
AROW: 112966034(ADAM12)
NPD: 112949974(ADAM12)
DNE: 112992690(ADAM12)
ASN: 102375297(ADAM12)
AMJ: 102558888(ADAM12)
CPOO: 109323991(ADAM12)
GGN: 109287705(ADAM12)
PSS: 102452843(ADAM12)
CMY: 102933922(ADAM12)
CPIC: 101934003(ADAM12)
TST: 117880013(ADAM12)
CABI: 116833351(ADAM12)
MRV: 120409193(ADAM12)
ACS: 100561819(adam12)
PVT: 110077927(ADAM12)
SUND: 121926598(ADAM12)
PGUT: 117676723(ADAM12)
VKO: 123031102(ADAM12)
PMUA: 114597386(ADAM12)
ZVI: 118096180(ADAM12)
STOW: 125437774(ADAM12)
XLA: 108696121(adam12.L) 108697349 108697394(adam12.S) 108704093
XTR: 677729(adam12)
NPR: 108788859(ADAM12)
RTEM: 120924592(ADAM33) 120946752(ADAM12)
BBUF: 121005169(ADAM12)
BGAR: 122941397(ADAM12)
DRE: 563275(adam12)
PPRM: 120462765 120476966(adam12b)
MAMB: 125269063(adam12b)
TFD: 113634087 113659728(adam12b)
AMEX: 103042729(adam12)
EEE: 113576647
ELY: 117246697 117247957(adam12)
PLEP: 121954728(adam12b) 121959295
SLUC: 116055504(adam12) 116061077
ECRA: 117937024 117960145(adam12)
GAT: 120819851 120820881(adam12b)
PPUG: 119212506 119214358(adam12)
MSAM: 119916298 119917348(adam12b)
CUD: 121511333(adam12b) 121528821
OAU: 116322224(adam12b) 116328806
OLA: 101155152(adam12) 101169556
OML: 112154517 112162267(adam12)
XMA: 102228824(adam12) 102229297
PLAI: 106949739(adam12)
PMEI: 106919503 106929851(adam12)
GAF: 122823792 122842681(adam12b)
CVG: 107093568
CTUL: 119781928 119783725(adam12b)
GMU: 124858575(adam12b) 124875228
NFU: 107375991(adam12) 107387781
KMR: 108245604(adam12b) 108246095
ALIM: 106513219 106516607(adam12)
NWH: 119423519 119430189(adam12b)
AOCE: 111569408
CSEM: 103381641(adam12) 103387673
SSEN: 122758868 122782068(adam12b)
HHIP: 117752663 117775580(adam12)
XGL: 120794095 120796913(adam12b)
SASA: 106577034(adam12) 106607406
ONE: 115113208 115135075(adam12)
SALP: 111952061(adam12) 111978661
SFM: 108932900(adam12)
PKI: 111859260
LOC: 102693085(adam12) 107076975
CMK: 103185464(adam12b)
CIN: 100184481
SCLV: 120345322
ACOZ: 120951885
AARA: 120908749
NVE: 116601185
AQU: 100635557
 » show all
Gilpin BJ, Loechel F, Mattei MG, Engvall E, Albrechtsen R, Wewer UM
A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo.
J Biol Chem 273:157-66 (1998)
Klein T, Bischoff R
Active metalloproteases of the A Disintegrin and Metalloprotease (ADAM) family: biological function and structure.
J Proteome Res 10:17-33 (2011)

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