KEGG   ORTHOLOGY: K07412Help
Entry
K07412                      KO                                     

Name
CYP2B
Definition
cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
Pathway
ko00140  Steroid hormone biosynthesis
ko00590  Arachidonic acid metabolism
ko00830  Retinol metabolism
ko01100  Metabolic pathways
ko05204  Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
   00590 Arachidonic acid metabolism
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07412  CYP2B; cytochrome P450 family 2 subfamily B
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K07412  CYP2B; cytochrome P450 family 2 subfamily B
BRITE hierarchy
Other DBs
RN: R03408 R07001 R07048 R07050 R07051 R07052 R08390 R08391 R08392
Genes
MMU: 13088(Cyp2b10) 13089(Cyp2b13) 13090(Cyp2b19) 13094(Cyp2b9) 243881(Cyp2b23)
MCAL: 110288440 110288965 110297861 110298448 110298729 110298847
MPAH: 110315594 110315789 110336742
RNO: 108348266 24300(Cyp2b1) 286953(Cyp2b3) 292728(Cyp2b21) 29295(Cyp2b12) 361523(Cyp2b2) 685222(Cyp2b15)
MUN: 110541208 110541305 110543018 110561195 110566202
CGE: 100759787 100760248 100762876 100763166 100763652 100765152 100765441 113837198 113838302
NGI: 103734439 103734444 103734445 103734446 103751524
HGL: 101700457 101711936 101712634 101713256 101716410
CCAN: 109680168 109680169 109703253
OCU: 100327257(CYP2B4) 100328947(CYP2B5) 100328948 100353574 100359087
TUP: 102479421 102494535
CFA: 474177(CYP2B6)
VVP: 112928354
AML: 100464347 100471209
UMR: 103677389 103677390
UAH: 113243545 113243547
ORO: 101366852 101385757
ELK: 111161484 111161535
FCA: 105259649 105260134
PTG: 102958471
PPAD: 109258033 109258034 109261476 109261906
BTA: 504769(CYP2B6) 530571
BOM: 102282243 102287777
BIU: 109572039 109573028
BBUB: 102389842 102403709
CHX: 102169213 102177329 108633257 108633327 108634920
OAS: 105608805 105614373 114117992
SSC: 102165015 403104(CYP2B22)
CFR: 102506939 102510644
CDK: 105093362 105093363
ECB: 100068569 100068603
EPZ: 103562352 103562353 103562356 103567950
EAI: 106843260 106843264 106843311 106843312 106843807
MYB: 102245131 106726521
MYD: 102751643
HAI: 109376598 109376600
DRO: 112319965
RAY: 107521826
MJV: 108405660 108405662
LAV: 100667350 100676654 100677786
TMU: 101341442 101358192
MDO: 100018927
SHR: 100931571
PCW: 110198215 110198316
OAA: 100074363
ASN: 102369937
AMJ: 102571887
CMY: 102947273
OBI: 106870542
 » show all
TaxonomyKoalaUniProt
Reference
PMID:6306654
  Authors
Mizukami Y, Sogawa K, Suwa Y, Muramatsu M, Fujii-Kuriyama Y
  Title
Gene structure of a phenobarbital-inducible cytochrome P-450 in rat liver.
  Journal
Proc Natl Acad Sci U S A 80:3958-62 (1983)
DOI:10.1073/pnas.80.13.3958
  Sequence
[rno:361523]
Reference
  Authors
Sun H, Lee CM, Tripathi S, Kim KB, Morgan ET
  Title
Nitric oxide-dependent CYP2B degradation is potentiated by a cytokine-regulated pathway and utilizes the immunoproteasome subunit LMP2.
  Journal
Biochem J 445:377-82 (2012)
DOI:10.1042/BJ20120820

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (16)   
   KEGG ENZYME (1)   
   KEGG REACTION (9)   
   KEGG RCLASS (6)   
Gene (176)   
   KEGG GENES (131)   
   RefGene (40)   
   OC (5)   
Protein sequence (44)   
   UniProt (35)   
   SWISS-PROT (9)   
Literature (2)   
   PubMed (2)   
All databases (251)   

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