KEGG   ORTHOLOGY: K07413Help
Entry
K07413                      KO                                     

Name
CYP2C
Definition
cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
Pathway
ko00140  Steroid hormone biosynthesis
ko00590  Arachidonic acid metabolism
ko00591  Linoleic acid metabolism
ko00830  Retinol metabolism
ko01100  Metabolic pathways
ko04726  Serotonergic synapse
ko04750  Inflammatory mediator regulation of TRP channels
ko05204  Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
   00590 Arachidonic acid metabolism
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
   00591 Linoleic acid metabolism
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07413  CYP2C; cytochrome P450 family 2 subfamily C
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K07413  CYP2C; cytochrome P450 family 2 subfamily C
BRITE hierarchy
Other DBs
RN: R03408 R07042 R07043 R07048 R07050 R07051 R07052 R07054 R07055 R07056 R08390 R08392
Genes
PON: 100449185
MCC: 100424240(CYP2C76) 678686(CYP2C75)
MCF: 102114994(CYP2C76)
RRO: 104664669
RBB: 108543807
CJC: 100391987(CYP2C76)
SBQ: 101040831
MMU: 107141(Cyp2c50) 13095(Cyp2c29) 13096(Cyp2c37) 13097(Cyp2c38) 13098(Cyp2c39) 13099(Cyp2c40) 226105(Cyp2c70) 226143(Cyp2c23) 404195(Cyp2c54) 433247(Cyp2c68) 69888(Cyp2c66) 72082(Cyp2c55) 72303(Cyp2c65)
MCAL: 110285299 110285739 110288497
MPAH: 110321409
RNO: 171518(Cyp2c22) 171521(Cyp2c13) 25011(Cyp2c12) 29277(Cyp2c11) 29298(Cyp2c7) 293989(Cyp2c6v1) 499353(Cyp2c24) 83790(Cyp2c23)
CCAN: 109675594
OCU: 100328549(CYP2C5) 100328924(CYP2C2) 100328933(CYP2C) 100328935(CYP2C30) 100328936(CYP2C14) 100328938(CYP2C16) 100345193 100346743(CYP2C1) 100349436(CYP2C4) 103351405
CFA: 100688697 415122(CYP2C18)
VVP: 112917651
UAH: 113251748
ELK: 111144947
PPAD: 109264682
BTA: 511498 616593(CYP2C87) 785540
SSC: 100739741 403107(CYP2C33)
BACU: 103017669
LVE: 103084494
OOR: 101280390
DLE: 111172397
PCAD: 102978514
EPZ: 103555431
DRO: 112300219
GGA: 100858007(RP11-400G3.5) 414833(CYP2C45)
MGP: 100544448
NMEL: 110399446
APLA: 101797318
ACYG: 106046725
GFR: 102043152
FAB: 101815619
CCW: 104695623
ETL: 114065370
AMJ: 102572949
CMY: 102931882
PVT: 110084010
PBI: 103054127
PMUR: 107296151
PMUA: 114590725
XLA: 108699286 379297(cyp2c8.1.S) 444542(cyp2c8.2.L)
XTR: 448236(cyp2c8.2)
AG: AAC08738(CYP2C41) BAA02001(CYP2C26) BAA02002(CYP2C27) BAA02003(CYP2C28) CAA44753(CYP2C25)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9721182
  Authors
Luo G, Zeldin DC, Blaisdell JA, Hodgson E, Goldstein JA
  Title
Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid.
  Journal
Arch Biochem Biophys 357:45-57 (1998)
DOI:10.1006/abbi.1998.0806
  Sequence
Reference
  Authors
Iliff JJ, Jia J, Nelson J, Goyagi T, Klaus J, Alkayed NJ
  Title
Epoxyeicosanoid signaling in CNS function and disease.
  Journal
Prostaglandins Other Lipid Mediat 91:68-84 (2010)
DOI:10.1016/j.prostaglandins.2009.06.004

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