KEGG   ORTHOLOGY: K07418Help
Entry
K07418                      KO                                     

Name
CYP2J
Definition
cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
Pathway
ko00590  Arachidonic acid metabolism
ko00591  Linoleic acid metabolism
ko01100  Metabolic pathways
ko04726  Serotonergic synapse
ko04750  Inflammatory mediator regulation of TRP channels
ko04913  Ovarian steroidogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
   00591 Linoleic acid metabolism
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
  09156 Nervous system
   04726 Serotonergic synapse
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07418  CYP2J; cytochrome P450 family 2 subfamily J
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07418  CYP2J; cytochrome P450 family 2 subfamily J
    1.14.14.73  albendazole monooxygenase (sulfoxide-forming)
     K07418  CYP2J; cytochrome P450 family 2 subfamily J
    1.14.14.74  albendazole monooxygenase (hydroxylating)
     K07418  CYP2J; cytochrome P450 family 2 subfamily J
    1.14.14.75  fenbendazole monooxygenase (4'-hydroxylating)
     K07418  CYP2J; cytochrome P450 family 2 subfamily J
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K07418  CYP2J; cytochrome P450 family 2 subfamily J
BRITE hierarchy
Other DBs
RN: R07042 R07043 R07044 R07045 R07046 R07048 R07050 R07051 R07052 R07055 R07056
Genes
HSA: 1573(CYP2J2)
PTR: 456896(CYP2J2)
PPS: 100984148
GGO: 101148349
PON: 100447634
NLE: 100589053
MCC: 693631
MCF: 102119662(CYP2J2)
CSAB: 103224719(CYP2J2)
RRO: 104668045
RBB: 108532916
CJC: 100397287(CYP2J2)
SBQ: 101041470
MMU: 100066(Cyp2j11) 13109(Cyp2j5) 13110(Cyp2j6) 230459(Cyp2j13) 242546(Cyp2j12) 665095(Cyp2j8) 74519(Cyp2j9)
RNO: 100912642 313373(Cyp2j10) 313375(Cyp2j3) 502969(Cyp2j16) 65210(Cyp2j4)
CCAN: 109684284
OCU: 100301544(CYP2J1)
CFA: 610195(CYP2J2)
AML: 100482335
UMR: 103663082
ORO: 101382939
FCA: 101097746
PTG: 102958105
AJU: 106974984
BIU: 109556228
PHD: 102335165
OAS: 101121820 768095(CYP2J)
LVE: 103072875
OOR: 101287985
ECB: 100067247
EPZ: 103564165
EAI: 106833456
MYB: 102259820
MYD: 102765527
HAI: 109389708
PALE: 102885276
TMU: 101350163
MDO: 100031975
SHR: 100921692
OAA: 100087745
GGA: 424676(CYP2J23) 424677(CYP2J22)
CJO: 107317691
APLA: 101792912
ACYG: 106033102
TGU: 100224220
GFR: 102039653
FAB: 101817417
PHI: 102112918
PMAJ: 107208256
CCW: 104695151
FPG: 101919387
FCH: 102056779
EGZ: 104123941
AMJ: 102557714(CYP2P10)
CMY: 102940076(CYP2J19)
ACS: 100567522
DRE: 100034366(cyp2p8) 100034406(cyp2p7)
SANH: 107665313
CCAR: 109112720
IPU: 108257767
PHYP: 113530771
MZE: 112429716
OLA: 100302452(cyp2p3)
CSEM: 103383190
BPEC: 110173990
SASA: 106584062
CMK: 103185273
CIN: 100181884
MPHA: 105830628
HST: 105190954
NVL: 108561496
BMOR: 101743283(CYP303A1)
PMAC: 106717103
PRAP: 111003399
HAW: 110376552
CLEC: 106665205
ZNE: 110837931
FCD: 110852911
BRP: 103864112
CPEP: 111802054
MESC: 110605837
CQI: 110715534
PSOM: 113343088
DOSA: Os02t0185900-01(Os02g0185900)
SITA: 101778178
MUS: 103995680
DFA: DFA_07281(CYP513C1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8631948
  Authors
Wu S, Moomaw CR, Tomer KB, Falck JR, Zeldin DC
  Title
Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart.
  Journal
J Biol Chem 271:3460-8 (1996)
DOI:10.1074/jbc.271.7.3460
  Sequence
[hsa:1573]
Reference
  Authors
Iliff JJ, Jia J, Nelson J, Goyagi T, Klaus J, Alkayed NJ
  Title
Epoxyeicosanoid signaling in CNS function and disease.
  Journal
Prostaglandins Other Lipid Mediat 91:68-84 (2010)
DOI:10.1016/j.prostaglandins.2009.06.004
Reference
  Authors
Scarborough PE, Ma J, Qu W, Zeldin DC
  Title
P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues.
  Journal
Drug Metab Rev 31:205-34 (1999)
DOI:10.1081/DMR-100101915

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