KEGG   ORTHOLOGY: K07424Help
Entry
K07424                      KO                                     

Name
CYP3A
Definition
cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
Pathway
ko00140  Steroid hormone biosynthesis
ko00591  Linoleic acid metabolism
ko00830  Retinol metabolism
ko01100  Metabolic pathways
ko05204  Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
   00591 Linoleic acid metabolism
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07424  CYP3A; cytochrome P450 family 3 subfamily A
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP3 family
   K07424  CYP3A; cytochrome P450 family 3 subfamily A
BRITE hierarchy
Other DBs
RN: R02356 R03408 R07055 R07056 R08390 R08391 R08392
Genes
CJC: 100404344(CYP3A4)
SBQ: 101037403
MMU: 100041375(Cyp3a41b) 13112(Cyp3a11) 13113(Cyp3a13) 13114(Cyp3a16) 337924(Cyp3a44) 53973(Cyp3a41a) 56388(Cyp3a25)
RNO: 100910877 170509(Cyp3a62) 171352(Cyp3a9) 252931(Cyp3a18) 25642(Cyp3a23/3a1) 266682(Cyp3a2)
CGE: 100766524 100767391 100773059 100773351
NGI: 103726479 103726480
HGL: 101700489
CCAN: 109701918 109702004
OCU: 100328954(CYP3A6)
CFA: 415129(CYP3A12)
AML: 100472647 105235077
UMR: 103669994 103669998 103669999
FCA: 100642187(CYP3A132) 100652377(CYP3A131)
PTG: 102957386(CYP3A131) 102957670
AJU: 106981196 106981197
BTA: 282214(CYP3A5) 507988(CYP3A4) 526682(CYP3A5)
BOM: 102284132 102284405 102284686 102284966
PHD: 102338455 102339063 102339423
CHX: 102168966 102181382 102191011 102191297(CYP3A)
OAS: 100170111(CYP3A24) 101110202 101110727
SSC: 100126281(CYP3A46) 100144468(CYP3A22) 403324(CYP3A29)
CFR: 102514805
CDK: 105099350
BACU: 103014952
LVE: 103081108
ECB: 100067041(CYP3A93) 100067064(CYP3A89) 100067084(CYP3A94) 100067109(CYP3A95) 100067131(CYP3A96)
EAI: 106825167
MYB: 102263738
MYD: 102756525 102762686
HAI: 109378053
LAV: 100658793 100677295
MDO: 100010745 100010783 100010820 100013114 100013238
SHR: 100918011
OAA: 100082218 100082250 100091970
GGA: 414832(CYP3A5) 416477(CYP3A4)
MGP: 678668(CYP3A80) 678669(CYP3A37)
CJO: 107320762 107320785
APLA: 101799374 101799795
ACYG: 106032071 106032170
TGU: 100223162 100226034
GFR: 102042286 102042456
FAB: 101815550 101818071
PHI: 102105124 102105300
CCW: 104684806 104684807
FPG: 101911664 101911836
FCH: 102049918 102050092
CLV: 102087823 102088003
EGZ: 104132595 104132596
AAM: 106495217 106495220
ASN: 102368695 102368945 102369208
AMJ: 102570482(CYP3A) 102570712
PSS: 102447293 102447714
CMY: 102938524
CPIC: 101944980 101945439 101945909
ACS: 100555955 100557851
PVT: 110083729 110091550
PBI: 103050164 103050666
GJA: 107117318 107117320 107123864 107125821
XLA: 100037189(cyp3a4) 398964 495363(cyp3a5.L)
XTR: 100487054 100487665 100487846 100494419 548503(cyp3a4)
NPR: 108804467
DRE: 553969(cyp3a65)
SANH: 107680745
SGH: 107574731
IPU: 108258748(CYP3A125)
TRU: 101069124
LCO: 104931688
XMA: 102219031 111608645
LCF: 108877940
SASA: 106568073
LCM: 102365730
CMK: 103185125
BFO: BRAFLDRAFT_201702 BRAFLDRAFT_280636
CIN: 100169892 100182809
SPU: 576854 578821 579059 581116 585008 586711 762372
SKO: 100371396
CRG: 105325143 105335480
NVE: NEMVE_v1g142057
TAD: TRIADDRAFT_13664
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3785219
  Authors
Gonzalez FJ, Song BJ, Hardwick JP
  Title
Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation.
  Journal
Mol Cell Biol 6:2969-76 (1986)
DOI:10.1128/MCB.6.8.2969
  Sequence
[rno:266682]
Reference
  Authors
McArthur AG, Hegelund T, Cox RL, Stegeman JJ, Liljenberg M, Olsson U, Sundberg P, Celander MC
  Title
Phylogenetic analysis of the cytochrome P450 3 (CYP3) gene family.
  Journal
J Mol Evol 57:200-11 (2003)
DOI:10.1007/s00239-003-2466-x

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (13)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
   KEGG RCLASS (5)   
Gene (1842)   
   KEGG GENES (170)   
   KEGG MGENES (32)   
   RefGene (1517)   
   EGENES (119)   
   OC (4)   
Protein sequence (77)   
   UniProt (65)   
   SWISS-PROT (12)   
Literature (2)   
   PubMed (2)   
All databases (1948)   

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