KEGG   ORTHOLOGY: K07424Help
Entry
K07424                      KO                                     

Name
CYP3A
Definition
cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
Pathway
ko00140  Steroid hormone biosynthesis
ko00591  Linoleic acid metabolism
ko00830  Retinol metabolism
ko01100  Metabolic pathways
ko05204  Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
   00591 Linoleic acid metabolism
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07424  CYP3A; cytochrome P450 family 3 subfamily A
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP3 family
   K07424  CYP3A; cytochrome P450 family 3 subfamily A
BRITE hierarchy
Other DBs
RN: R02356 R03408 R07055 R07056 R08390 R08391 R08392
Genes
CJC: 100404344(CYP3A4)
SBQ: 101037403
MMU: 100041375(Cyp3a41b) 13112(Cyp3a11) 13113(Cyp3a13) 13114(Cyp3a16) 337924(Cyp3a44) 53973(Cyp3a41a) 56388(Cyp3a25)
RNO: 100910877 170509(Cyp3a62) 171352(Cyp3a9) 252931(Cyp3a18) 25642(Cyp3a23/3a1) 266682(Cyp3a2)
CGE: 100766524 100767391 100773059 100773351
NGI: 103726479 103726480
HGL: 101700489
CCAN: 109701918 109702004
OCU: 100328954(CYP3A6)
CFA: 415129(CYP3A12)
FCA: 100642187(CYP3A132) 100652377(CYP3A131)
PTG: 102957386(CYP3A131) 102957670
BTA: 282214(CYP3A5) 507988(CYP3A4) 526682(CYP3A5)
SSC: 100126281(CYP3A46) 100144468(CYP3A22) 403324(CYP3A29)
CFR: 102514805
CDK: 105099350
BACU: 103014952
LVE: 103081108
ECB: 100067041(CYP3A93) 100067064(CYP3A89) 100067084(CYP3A94) 100067109(CYP3A95) 100067131(CYP3A96)
EAI: 106825167
MYB: 102263738
HAI: 109378053
SHR: 100918011
GGA: 414832(CYP3A5) 416477(CYP3A4)
MGP: 678668(CYP3A80) 678669(CYP3A37)
AMJ: 102570482(CYP3A) 102570712
CMY: 102938524
XLA: 100037189(cyp3a4) 398964 495363(cyp3a5.L)
NPR: 108804467
DRE: 553969(cyp3a65)
SANH: 107680745
SGH: 107574731
IPU: 108258748(CYP3A125)
TRU: 101069124
LCO: 104931688
LCF: 108877940
SASA: 106568073
LCM: 102365730
CMK: 103185125
SKO: 100371396
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3785219
  Authors
Gonzalez FJ, Song BJ, Hardwick JP
  Title
Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation.
  Journal
Mol Cell Biol 6:2969-76 (1986)
DOI:10.1128/MCB.6.8.2969
  Sequence
[rno:266682]
Reference
  Authors
McArthur AG, Hegelund T, Cox RL, Stegeman JJ, Liljenberg M, Olsson U, Sundberg P, Celander MC
  Title
Phylogenetic analysis of the cytochrome P450 3 (CYP3) gene family.
  Journal
J Mol Evol 57:200-11 (2003)
DOI:10.1007/s00239-003-2466-x

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