KEGG   ORTHOLOGY: K07665Help
Entry
K07665                      KO                                     

Name
cusR, copR, silR
Definition
two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
Pathway
ko02020  Two-component system
Module
M00452  CusS-CusR (copper tolerance) two-component regulatory system
M00745  Imipenem resistance, repression of porin OprD
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   02020 Two-component system
    K07665  cusR, copR, silR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
KEGG modules [BR:ko00002]
 Functional set
  Environmental information processing
   Two-component regulatory system
    M00452  CusS-CusR (copper tolerance) two-component regulatory system
     K07665  cusR, copR, silR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
 Signature module
  Gene set
   Drug resistance
    M00745  Imipenem resistance, repression of porin OprD
     K07665  cusR, copR, silR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
Two-component system [BR:ko02022]
 OmpR family
  CusS-CusR
   K07665  cusR, copR, silR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  beta-Lactam resistance modules
   Imipenem resistance, repression of porin OprD
    K07665  cusR, copR, silR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
BRITE hierarchy
Other DBs
COG: COG0745
GO: 0000156
Genes
ECO: b0571(cusR)
ECJ: JW0560(cusR)
ECD: ECDH10B_0529(cusR) ECDH10B_0637(cusR)
EBW: BWG_0442(cusR)
ECOK: ECMDS42_0437(cusR)
ECE: Z0709(ylcA)
ECS: ECs0609
ECF: ECH74115_0651(cusR)
ETW: ECSP_0623(cusR)
ELX: CDCO157_0593
EOJ: ECO26_0643(cusR)
EOI: ECO111_0598(cusR)
EOH: ECO103_0576(cusR)
ECG: E2348C_0471(cusR)
EOK: G2583_0732(cusR)
ECC: c0657(cusR)
ECP: ECP_0602
ECI: UTI89_C0571(ylcA)
ECV: APECO1_1477(ylcA) APECO1_O1R110(silR) APECO1_O1R122.2(pcoR)
ECX: EcHS_A0618(cusR)
ECW: EcE24377A_0589(cusR)
ECM: EcSMS35_0588(cusR)
ECY: ECSE_0635
ECR: ECIAI1_0551(cusR)
ECQ: ECED1_0563(cusR)
ECT: ECIAI39_0546(cusR)
EOC: CE10_0569(cusR)
EUM: ECUMN_0661(cusR)
ECZ: ECS88_0607(cusR)
ELO: EC042_0605(cusR)
ESE: ECSF_0501
EBR: ECB_00532(cusR)
EBD: ECBD_3091
EKF: KO11_20825(cusR)
EAB: ECABU_c06200(cusR)
EDJ: ECDH1ME8569_0539(cusR)
EIH: ECOK1_0580(cusR)
ENA: ECNA114_0502(cusR)
EUN: UMNK88_599(irlR)
ELW: ECW_m0623(cusR)
ELL: WFL_03095(cusR)
ELC: i14_0631(cusR)
ELD: i02_0631(cusR)
ELP: P12B_c0554(ylcA) P12B_c3594(pcoR) P12B_c3611(silR)
EBL: ECD_00532(cusR)
EBE: B21_00521(cusR)
ELF: LF82_0389(cusR) LF82_251
ECOI: ECOPMV1_00587(cusR)
ECOJ: P423_02745
ECOO: ECRM13514_0589(ylcA)
ECOH: ECRM13516_0532(ylcA)
ECOS: EC958_0678(ylcA)
EFE: EFER_2540(cusR)
EAL: EAKF1_ch0891(cusR)
SFL: SF0472(ylcA)
SFX: S0480(ylcA)
SFV: SFV_0504(ylcA)
SFE: SFxv_0519(cusR)
SFN: SFy_0601
SFS: SFyv_0639
SFT: NCTC1_00488(cusR)
SSN: SSON_0522(ylcA)
ENC: ECL_01959(cusR) ECL_04877(pcoR) ECL_04897(cusR) ECL_A015(pcoR) ECL_A035(cusR)
EEC: EcWSU1_02216(cusR)
CTU: Ctu_3p00510(pcoR) Ctu_3p00670(silR)
KPU: KP1_0690 KP1_p136(pcoR) KP1_p153(silR)
KPT: VK055_2704(copR)
KPE: KPK_4903(cusR)
KPR: KPR_0803
KPX: PMK1_02195(cusR) PMK1_a00102(copR) PMK1_a00116(cusR)
KPNK: BN49_4706
KVA: Kvar_4536
KOX: KOX_02230
KOE: A225_4890
EAE: EAE_09990
EAR: CCG31994
CKO: CKO_02615
EBT: EBL_c00340(cusR)
YPE: YPO2001(copR)
YPK: y2307
YPA: YPA_1383
YPN: YPN_1481
YPM: YP_1848(copR)
YPZ: YPZ3_1817(copR)
YPD: YPD4_1765(copR)
YPX: YPD8_1783(copR)
YPH: YPC_2320(copR)
YPW: CH59_4125
YPJ: CH55_734
YPV: BZ15_1538
YPL: CH46_3112
YPS: YPTB1993(copR)
YPO: BZ17_474
YPY: YPK_2192
YPB: YPTS_2050
YPQ: DJ40_318
YPU: BZ21_1271
YPR: BZ20_120
YPC: BZ23_1553
YPF: BZ19_1343
YEN: YE3024(copR)
YEW: CH47_2393
YET: CH48_2788
SPE: Spro_1498
SRL: SOD_c13850(czcR)
SMAF: D781_3623
SERF: L085_21035
RAA: Q7S_06655
SGL: SG1536
SOD: Sant_2316(czcR) Sant_2401(irlR)
DDQ: DDI_0521
EBI: EbC_09000 EbC_25590(copR)
EGE: EM595_p1077(pcoR)
PRG: RB151_006620(cusR)
ETR: ETAE_1663(ylcA)
ETD: ETAF_1503(cusR)
ETE: ETEE_3710(cusR)
SML: Smlt2693
SMT: Smal_2165
SMZ: SMD_2366(cusR)
LEZ: GLE_1780
LEM: LEN_0528 LEN_3195(cusR)
VVU: VV2_0991
VVY: VVA1484
VPA: VP0361
VPB: VPBB_0368
VFI: VF_A0179(cusR)
PPR: PBPRA0986(IRLR) PBPRA1001(RS00367)
PAE: PA1437 PA2523 PA2809(copR) PA4885(irlR)
PAU: PA14_27810(copR) PA14_31960(czrR) PA14_45880 PA14_64570(irlR)
PNC: NCGM2_0641(irlR) NCGM2_2320 NCGM2_3528(czrR) NCGM2_3903(copR)
PMK: MDS_2489
PRE: PCA10_35990(copR)
PPSE: BN5_2076(copR) BN5_4410(cusR)
PCQ: PcP3B5_00910(czcR_1) PcP3B5_22260(copR)
PPU: PP_1438(czcR-III) PP_2158(copR-I) PP_5383(copR-II)
PFS: PFLU_0701(czcR) PFLU_0959(cusR) PFLU_1576(cusR) PFLU_4171
PSA: PST_2712 PST_3390 PST_3421(czrR-2)
PSZ: PSTAB_1240(czrR) PSTAB_2504(copR) PSTAB_2696(copR)
PSR: PSTAA_2833(copR) PSTAA_3529 PSTAA_3538(czrR-2) PSTAA_4039(czrR-1)
PKC: PKB_0233(czcR) PKB_1727 PKB_3442(copR)
PSEC: CCOS191_3569(copR) CCOS191_4163(czcR1) CCOS191_4475(czcR2)
PAR: Psyc_1596
PALI: A3K91_1824
PSYC: DABAL43B_1570(copR)
ACB: A1S_2937
ABY: ABAYE3203(copR)
ABN: AB57_0661
ABB: ABBFA_001250(irlR)
ABAA: IX88_13620
ACC: BDGL_001714(irlR)
ASJ: AsACE_p100072(cusR)
SLO: Shew_3258
PHA: PSHAb0012(cusR)
PTN: PTRA_b0012(cusR)
PART: PARC_a0500(cusR)
PNG: PNIG_b0014(cusR)
AMAL: I607_01380
AMAE: I876_01635
AMAO: I634_01595
AMAD: I636_01365
AMAI: I635_01395
AMAG: I533_01330
AAUS: EP12_10685
SDE: Sde_1948
SAGA: M5M_02885
LPH: LPV_0839(cusR)
LPO: LPO_0796(cusR)
LPM: LP6_0697(ompR)
LPP: lpp0781
LPC: LPC_2578
LPA: lpa_01105(ompR)
LPE: lp12_0724
MAH: MEALZ_1701(mprA)
MEJ: Q7A_1812
TGR: Tgr7_1208
TNI: TVNIR_1101(irlR_[H])
HCH: HCH_03613
CSA: Csal_0102
APAC: S7S_14185
KKO: Kkor_1292
OCE: GU3_04980
SLIM: SCL_0973
SVA: SVA_3239
PSE: NH8B_2345
RSO: RSp0489(czcR) RSp0655(copR)
RSL: RPSI07_mp0425(czcR) RPSI07_mp0532(copR)
RSN: RSPO_m00327(czcR) RSPO_m00428(copR)
RSM: CMR15_mp10467(czcR) CMR15_mp10608(copR)
RSE: F504_3876 F504_4568(cusR)
REH: H16_A2167(czrR) H16_B1647(h16_B1647) H16_B2186(copR)
RME: Rmet_1751(agrR) Rmet_4465(czcR2) Rmet_5672(copR2) Rmet_6111(copR1)
CTI: RALTA_B1458(czcR) RALTA_B1969(copR)
CGD: CR3_0173(copR) CR3_1322(copR) CR3_1356(czcR) CR3_1379(copR) CR3_3545(cusR)
BMA: BMAA1028(irlR)
BMV: BMASAVP1_0010(irlR)
BML: BMA10229_0402(irlR)
BMN: BMA10247_A1180(irlR)
BMAL: DM55_4630
BMAQ: DM76_3583
BMAI: DM57_11540
BMAF: DM51_4707
BMAZ: BM44_4309
BMAB: BM45_3433
BPS: BPSS1040(irlR) BPSS1994(irlR2)
BPSU: BBN_4506 BBN_5462(copR)
BPSD: BBX_4574(copR) BBX_6179
BPZ: BP1026B_II1139(irlR) BP1026B_II2142(irlR2)
BPK: BBK_4737(copR) BBK_6101
BPSA: BBU_4014(copR) BBU_4983
BTQ: BTQ_3669(copR) BTQ_4662
BTJ: BTJ_4702(copR) BTJ_5600
BTHM: BTRA_4299 BTRA_5428(copR)
BUK: MYA_4374
PPNM: LV28_01670
PPUL: RO07_03835
PAPI: SG18_19710
BPAR: BN117_4143
BBR: BB4542
BPT: Bpet4609
BAV: BAV2048(irlR)
BHZ: ACR54_04223(czcR)
AXY: AXYL_01121(irlR2) AXYL_04680(irlR4) AXYL_05742(irlR5) AXYL_06101(irlR6)
AXX: ERS451415_00282(copR_1) ERS451415_00494(copR_2) ERS451415_02574(copR_4)
ODI: ODI_R3830
RFR: Rfer_0422
PNA: Pnap_4558
ACRA: BSY15_98
VEI: Veis_0344
DAC: Daci_0451
LIM: L103DPR2_02309(copR)
HAR: HEAR0538(cusR1) HEAR0604 HEAR1552(cusR2)
MMS: mma_0023 mma_0794(copR1) mma_1722(copR2) mma_2354(czcR2)
HSE: Hsero_0015(czcR) Hsero_2484 Hsero_3052(czcR)
TIN: Tint_1277
THI: THI_1599(czcR) THI_3093(cusR)
TBD: Tbd_1749
MEP: MPQ_0415(ompR)
EBA: ebA2024
AZO: azo2946(copR)
AZA: AZKH_3915(copR_cusR)
AOA: dqs_3086
GSU: GSU2946(czcR)
GSK: KN400_2890(czcR)
GME: Gmet_0528(czcR)
GUR: Gura_1986
GBM: Gbem_3465(cusR) Gbem_3615(czcR)
GEO: Geob_3169(czcR)
ACR: Acry_3106
MAGX: XM1_3530(cusR)
MAGN: WV31_05700
TMO: TMO_c0013(cusR)
ALL: CRK58752
DMG: GY50_1056
OBG: Verru16b_01188(cusR)
MIN: Minf_2199(ompR)
PIR: VN12_21960(copR)
PLM: Plim_2757
PLS: VT03_06605(copR_1) VT03_10635(copR_2)
GES: VT84_08060(cusR) VT84_12805(czcR_2)
SACI: Sinac_6762
PBOR: BSF38_00063(mprA_1) BSF38_05261(mprA_3)
ACA: ACP_2862(copR)
TAI: Taci_0717
GBA: J421_1959
LBY: Lbys_3025
FAE: FAES_2224(ompR)
FJO: Fjoh_3918
CABY: Cabys_2518
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Outten FW, Huffman DL, Hale JA, O'Halloran TV
  Title
The independent cue and cus systems confer copper tolerance during aerobic and anaerobic growth in Escherichia coli.
  Journal
J Biol Chem 276:30670-7 (2001)
DOI:10.1074/jbc.M104122200
  Sequence
[eco:b0571]

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