KEGG   ORTHOLOGY: K07901
Entry
K07901                      KO                                     

Symbol
RAB8A, MEL
Name
Ras-related protein Rab-8A
Pathway
map04140  Autophagy - animal
map04144  Endocytosis
map04152  AMPK signaling pathway
map04530  Tight junction
map04972  Pancreatic secretion
map05014  Amyotrophic lateral sclerosis
map05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
   04140 Autophagy - animal
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
 09150 Organismal Systems
  09154 Digestive system
   04972 Pancreatic secretion
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
   05022 Pathways of neurodegeneration - multiple diseases
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
   03036 Chromosome and associated proteins
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
   04031 GTP-binding proteins
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
Membrane trafficking [BR:ko04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab GTPases
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
 Autophagy
  Other autophagy associated proteins
   Rab GTPases
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Other centriole associated proteins
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K07901  RAB8A, MEL; Ras-related protein Rab-8A
  Exosomal proteins of other body fluids (saliva and urine)
   K07901  RAB8A, MEL; Ras-related protein Rab-8A
  Exosomal proteins of colorectal cancer cells
   K07901  RAB8A, MEL; Ras-related protein Rab-8A
GTP-binding proteins [BR:ko04031]
 Small (monomeric) G-proteins
  Rab Family
   Rab8/10/13 [OT]
    K07901  RAB8A, MEL; Ras-related protein Rab-8A
Genes
HSA: 4218(RAB8A)
PTR: 468760(RAB8A)
PPS: 100993687(RAB8A)
GGO: 101128473(RAB8A)
PON: 100174026(RAB8A)
NLE: 100593627(RAB8A)
MCC: 100423251(RAB8A)
MCF: 102139595(RAB8A)
CSAB: 103234098(RAB8A)
CATY: 105571314(RAB8A)
PANU: 101014385(RAB8A)
RRO: 104661005(RAB8A)
RBB: 108543281(RAB8A)
TFN: 117074866(RAB8A)
PTEH: 111554270(RAB8A)
CJC: 100413294(RAB8A)
SBQ: 101052643(RAB8A)
MMU: 17274(Rab8a)
MCAL: 110299787(Rab8a)
MPAH: 110336451(Rab8a)
RNO: 117103(Rab8a)
MCOC: 116069541(Rab8a)
MUN: 110558748(Rab8a)
CGE: 100760856(Rab8a)
PLEU: 114709578(Rab8a)
NGI: 103726929(Rab8a)
HGL: 101709178(Rab8a)
CCAN: 109689056(Rab8a)
OCU: 103345363(RAB8A)
TUP: 102481788(RAB8A)
CFA: 403773(RAB8A)
VVP: 112913135(RAB8A)
VLG: 121495907(RAB8A)
AML: 100471245(RAB8A)
UMR: 103677160(RAB8A)
UAH: 113256641(RAB8A)
ORO: 101382160(RAB8A)
ELK: 111144096
MPUF: 101687916(RAB8A)
EJU: 114196403(RAB8A)
MLX: 118005026(RAB8A)
FCA: 101092668(RAB8A)
PYU: 121010943(RAB8A)
PTG: 102959409(RAB8A)
PPAD: 109247530(RAB8A)
AJU: 106985924(RAB8A)
HHV: 120239195(RAB8A)
BTA: 100125881(RAB8A)
BOM: 102287920(RAB8A)
BIU: 109561469(RAB8A)
BBUB: 102403442(RAB8A)
CHX: 102180027(RAB8A)
OAS: 100302063(RAB8A)
ODA: 120864186(RAB8A)
CCAD: 122440668(RAB8A)
SSC: 100511006(RAB8A)
CFR: 102517974(RAB8A)
CBAI: 105082521(RAB8A)
CDK: 105101820(RAB8A)
BACU: 103008180(RAB8A)
LVE: 103090586(RAB8A)
OOR: 101274200(RAB8A)
DLE: 111166597(RAB8A)
PCAD: 102993114(RAB8A)
ECB: 100147248(RAB8A)
EPZ: 103540446(RAB8A)
EAI: 106846855(RAB8A)
MYB: 102251536(RAB8A)
MYD: 102754443(RAB8A) 102762935
MMYO: 118652600(RAB8A) 118676521
MNA: 107534318(RAB8A)
HAI: 109382492(RAB8A)
DRO: 112305194(RAB8A)
SHON: 118975065(RAB8A)
AJM: 119046771(RAB8A)
MMF: 118615433(RAB8A)
PALE: 102888123(RAB8A)
PGIG: 120606489(RAB8A)
RAY: 107517240(RAB8A)
MJV: 108384584(RAB8A)
TOD: 119241068(RAB8A)
LAV: 100656411(RAB8A)
TMU: 101353683
MDO: 100014326(RAB8A)
SHR: 100935197(RAB8A)
PCW: 110196121(RAB8A)
OAA: 100092137(RAB8A)
GGA: 428352(RAB8A)
PCOC: 116235682(RAB8A)
MGP: 100550722(RAB8A)
CJO: 107325492(RAB8A)
NMEL: 110389035(RAB8A)
APLA: 101791620(RAB8A)
ACYG: 106044942(RAB8A)
TGU: 100218529(RAB8A)
LSR: 110475738(RAB8A)
SCAN: 103824119(RAB8A)
PMOA: 120495622(RAB8A)
GFR: 102043991(RAB8A)
FAB: 101809085(RAB8A)
PHI: 102113707(RAB8A)
PMAJ: 107215491(RAB8A)
CCAE: 111940188(RAB8A)
CCW: 104697398(RAB8A)
ETL: 114067126(RAB8A)
FPG: 101913169(RAB8A)
FCH: 114015175(RAB8A)
CLV: 102097582(RAB8A)
EGZ: 104124364(RAB8A)
NNI: 104018731(RAB8A)
ACUN: 113489287(RAB8A)
PADL: 103912199(RAB8A)
AAM: 106494271(RAB8A)
NPD: 112943927(RAB8A)
ASN: 102370005(RAB8A)
AMJ: 102562145(RAB8A)
CPOO: 109312384(RAB8A)
GGN: 109295023(RAB8A)
PSS: 102456567
CMY: 102930684(RAB8A)
CPIC: 101932906(RAB8A)
TST: 117868972(RAB8A)
CABI: 116823151(RAB8A)
ACS: 100562397(rab3a)
PVT: 110072550(RAB8A)
PBI: 103050395(RAB8A)
PMUR: 107282209(RAB8A)
TSR: 106554669(RAB8A)
PGUT: 117677392(RAB8A)
PMUA: 114588301(RAB8A)
ZVI: 118085926(RAB8A)
GJA: 107121692(RAB8A)
XLA: 100037230(rab8a.S) 108713072(rab8a.L)
XTR: 100125217(rab8a)
NPR: 108786379(RAB8A)
DRE: 571897(rab8a)
IPU: 108280646(rab8a)
PHYP: 113533506(rab8a)
AMEX: 103043778(rab8a)
EEE: 113582881(rab8a)
TRU: 101062202(rab8a) 101063247
LCO: 104923634(rab8a) 104931433
CGOB: 115007248(rab8a) 115022501
PFLV: 114561920(rab8a) 114565535
MZE: 101474139 101478042(rab8a)
ONL: 100691063(rab8a) 100703352
OML: 112147397(rab8a) 112150656
XMA: 102219409 102224336(rab8a)
XHE: 116721370 116726121(rab8a)
PRET: 103463528(rab8a) 103479775
NFU: 107383584 107393169(rab8a)
KMR: 108230828 108232971(rab8a)
POV: 109625591(rab8a) 109644187
LCF: 108881393(rab8a) 108884188
SDU: 111231003 111232134(rab8a)
BPEC: 110160110(rab8a) 110164087
MALB: 109955457 109967420(rab8a)
ELS: 105011476(rab8a) 105022474
PKI: 111847608 111860317(rab8a)
LOC: 102695032(rab8a)
PSPA: 121301190 121301668(rab8a)
LCM: 102348304(RAB8A)
CMK: 103184518(rab8a)
BBEL: 109468954
SPU: 373318(rab8) 591568
APLC: 110979418
SKO: 100370066
DME: Dmel_CG8287(Rab8)
DER: 6545858
DSE: 6619413
DSI: Dsimw501_GD12244(Dsim_GD12244)
DAN: 6493710
DPE: 6602300
DWI: 6638725
DGR: 6558530
DAZ: 108613026
DNV: 108651485
DHE: 111604473
DVI: 6624496
CCAT: 101450306
MDE: 101887792
LCQ: 111685654
ACOZ: 120952839
AARA: 120896116
AAG: 5572947
CPII: 120412943
AME: 100576085
BIM: 100743836
BBIF: 117217094
BTER: 100647998
CCAL: 108623336
OBB: 114877884
MGEN: 117222410
NMEA: 116430756
CGIG: 122402277
SOC: 105202507
MPHA: 105833438
AEC: 105144888
ACEP: 105620326
PBAR: 105425839
VEM: 105558084
HST: 105192256
DQU: 106744062
CFO: 105257665
FEX: 115243550
LHU: 105673602
PGC: 109862777
OBO: 105275870
PCF: 106787700
NVI: 100115259
CSOL: 105364679
MDL: 103573167
CCIN: 107269017
TCA: 660542
DPA: 109545177
ATD: 109598622
AGB: 108908851
LDC: 111509529
NVL: 108563035
OTU: 111423916
BMOR: 732877
BMAN: 114243950
MSEX: 115448337
BANY: 112044361
PMAC: 106712056
PPOT: 106100954
PXU: 106119940
PRAP: 110994285
ZCE: 119828860
HAW: 110376420
TNL: 113505027
PXY: 105391631
API: 100160370
DNX: 107161372
AGS: 114118984
RMD: 113559410
BTAB: 109033756
DCI: 103515406
CLEC: 106661922
HHAL: 106686463
NLU: 111058300
ZNE: 110830488
CSEC: 111871581
FCD: 110842746
DMK: 116924753
PVM: 113819128
HAME: 121854264
HAZT: 108674370
EAF: 111703204
DSV: 119456078
RSAN: 119393617
RMP: 119172086
VDE: 111243524
VJA: 111267332
TUT: 107361677
CSCU: 111626050
PTEP: 107455249
SDM: 118184136
CEL: CELE_D1037.4(rab-8)
CBR: CBG12025(Cbr-rab-8)
BMY: BM_BM3010(Bma-rab-8) BM_BM4761(Bm4761)
TSP: Tsp_08052
BGT: 106051305
GAE: 121373235
MYI: 110454483
OBI: 106867762
EPA: 110253865
ATH: AT3G09900(RABE1e) AT3G46060(RABE1c) AT3G53610(RAB8) AT5G03520(RAB8C) AT5G59840
LJA: Lj0g3v0073999.1(Lj0g3v0073999.1) Lj0g3v0074009.1(Lj0g3v0074009.1) Lj0g3v0160049.1(Lj0g3v0160049.1) Lj0g3v0345339.1(Lj0g3v0345339.1) Lj0g3v0345339.2(Lj0g3v0345339.2) Lj0g3v0356479.1(Lj0g3v0356479.1) Lj0g3v0356489.1(Lj0g3v0356489.1) Lj1g3v1798830.2(Lj1g3v1798830.2) Lj1g3v4554710.1(Lj1g3v4554710.1) Lj1g3v4554720.1(Lj1g3v4554720.1) Lj3g3v3166220.1(Lj3g3v3166220.1) Lj5g3v0614770.1(Lj5g3v0614770.1) Lj5g3v0614780.1(Lj5g3v0614780.1) Lj5g3v2264070.1(Lj5g3v2264070.1) Lj5g3v2264080.1(Lj5g3v2264080.1)
RCU: 8261607
DOSA: Os03t0819900-01(Os03g0819900) Os05t0461300-01(Os05g0461300) Os07t0195100-01(Os07g0195100) Os07t0239400-01(Os07g0239400)
VCN: VOLCADRAFT_83299(rabE)
MNG: MNEG_2989
SCE: YFL005W(SEC4)
ERC: Ecym_7305
KMX: KLMA_30127(SEC4)
NCS: NCAS_0C04020(NCAS0C04020) NCAS_0J00630(NCAS0J00630)
NDI: NDAI_0G03340(NDAI0G03340)
TPF: TPHA_0P00360(TPHA0P00360)
TBL: TBLA_0D02650(TBLA0D02650)
TDL: TDEL_0C00980(TDEL0C00980)
KAF: KAFR_0B01660(KAFR0B01660) KAFR_0C03330(KAFR0C03330)
PIC: PICST_89948(SEC4)
CAL: CAALFM_CR01750CA(SEC4)
SLB: AWJ20_5011(SEC4)
BBRX: BRETT_000170(SEC4)
NCR: NCU06404
NTE: NEUTE1DRAFT78959(NEUTE1DRAFT_78959)
MGR: MGG_06135
SSCK: SPSK_03590
MAW: MAC_01311
MAJ: MAA_06335
CMT: CCM_07176
BFU: BCIN_01g00550(Bcsas1)
MBE: MBM_00620
ANI: AN6974.2
ANG: ANI_1_124(An14g00010)
ABE: ARB_06033
PTE: PTT_09780
SPO: SPAC9E9.07c(ypt2)
CNE: CNC04340
CNB: CNBC2840
TASA: A1Q1_07082
ABP: AGABI1DRAFT110016(AGABI1DRAFT_110016)
ABV: AGABI2DRAFT190094(AGABI2DRAFT_190094)
MGL: MGL_0134
MRT: MRET_1185
DDI: DDB_G0276399(rab8B) DDB_G0280043(rab8A)
DFA: DFA_07245(rab8B) DFA_12122(rabC)
EHI: EHI_003020 EHI_008640(114.t00023) EHI_053150(4.t00017) EHI_127380(123.t00008) EHI_199820(95.t00027)
SMIN: v1.2.009167.t1(symbB.v1.2.009167.t1) v1.2.017627.t1(symbB.v1.2.017627.t1)
PTI: PHATRDRAFT_30139(Sec4)
EHX: EMIHUDRAFT_439586(Rab8)
 » show all
Reference
  Authors
Bryant DM, Datta A, Rodriguez-Fraticelli AE, Peranen J, Martin-Belmonte F, Mostov KE
  Title
A molecular network for de novo generation of the apical surface and lumen.
  Journal
Nat Cell Biol 12:1035-45 (2010)
DOI:10.1038/ncb2106
Reference
PMID:8294494
  Authors
Zahraoui A, Joberty G, Arpin M, Fontaine JJ, Hellio R, Tavitian A, Louvard D
  Title
A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells.
  Journal
J Cell Biol 124:101-15 (1994)
DOI:10.1083/jcb.124.1.101
  Sequence
[hsa:4218]

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