KEGG   ORTHOLOGY: K07992
Entry
K07992                      KO                                     
Symbol
TYROBP, DAP12
Name
TYRO protein tyrosine kinase binding protein
Pathway
map04380  Osteoclast differentiation
map04650  Natural killer cell mediated cytotoxicity
Disease
H00438  Nasu-Hakola disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K07992  TYROBP, DAP12; TYRO protein tyrosine kinase binding protein
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K07992  TYROBP, DAP12; TYRO protein tyrosine kinase binding protein
Genes
HSA: 7305(TYROBP)
PTR: 455968(TYROBP)
GGO: 101125697(TYROBP)
PPYG: 129019532(TYROBP)
NLE: 100584467(TYROBP)
HMH: 116478929(TYROBP)
SSYN: 129459876(TYROBP)
MCC: 574207(TYROBP)
MCF: 102124022(TYROBP)
MTHB: 126942100
MNI: 105495491(TYROBP)
CSAB: 103234547(TYROBP)
CATY: 105578201(TYROBP)
PANU: 101015351(TYROBP)
TGE: 112613397(TYROBP)
MLEU: 105543073(TYROBP)
RRO: 104666669(TYROBP)
RBB: 108513050(TYROBP)
TFN: 117092384(TYROBP)
PTEH: 111530960(TYROBP)
CANG: 105516300(TYROBP)
CJC: 100393633(TYROBP)
SBQ: 101053468(TYROBP)
CIMI: 108306271
ANAN: 105706932(TYROBP)
CSYR: 103276226(TYROBP)
MMUR: 105876902(TYROBP)
LCAT: 123624448
PCOQ: 105816224(TYROBP)
OGA: 100952960(TYROBP)
MMU: 22177(Tyrobp)
MCAL: 110297724(Tyrobp)
MPAH: 110334844(Tyrobp)
RNO: 361537(Tyrobp)
MCOC: 116100338(Tyrobp)
ANU: 117719835(Tyrobp)
MUN: 110550864(Tyrobp)
CGE: 100772456(Tyrobp)
MAUA: 101840844
PROB: 127238750(Tyrobp)
PLEU: 114681639
MORG: 121450015
MFOT: 126486764
AAMP: 119820937
NGI: 103729945(Tyrobp)
HGL: 101707522(Tyrobp)
CPOC: 100726186(Tyrobp)
CCAN: 109689314(Tyrobp)
DORD: 105993113(Tyrobp)
DSP: 122097519
PLOP: 125368412
NCAR: 124966426
MMMA: 107151825
OCU: 103345430
OPI: 101530146
TUP: 102496599(TYROBP)
GVR: 103592811(TYROBP)
CFA: 476477(TYROBP)
CLUD: 112643619
VVP: 112928547(TYROBP)
VLG: 121484864
NPO: 129500534(TYROBP)
AML: 100477572(TYROBP)
UMR: 103682527
UAH: 113244840(TYROBP)
UAR: 123793881
ELK: 111161505
LLV: 125088453
MPUF: 101674756(TYROBP)
MNP: 132004800(TYROBP)
MLK: 131818057(TYROBP)
NVS: 122911575
ORO: 101378429(TYROBP)
EJU: 114224412(TYROBP)
ZCA: 113935651
MLX: 118022871(TYROBP)
NSU: 110590156
LWW: 102735206(TYROBP)
FCA: 101082964(TYROBP)
PYU: 121011536
PCOO: 112851052(TYROBP)
PBG: 122495055
PVIV: 125153609(TYROBP)
LRUF: 124511206
PTG: 102964980(TYROBP)
PPAD: 109251496(TYROBP)
PUC: 125915104
AJU: 106974710
HHV: 120243469
BTA: 282390(TYROBP)
BOM: 102279887(TYROBP)
BIU: 109572395(TYROBP)
BBUB: 102406319
BBIS: 104995265(TYROBP)
CHX: 102175151(TYROBP)
OAS: 443208(TYROBP)
BTAX: 128063695(TYROBP)
ODA: 120872573
CCAD: 122421467
MBEZ: 129546139(TYROBP)
SSC: 397405(TYROBP)
CFR: 102509258(TYROBP)
CBAI: 105065063(TYROBP)
CDK: 105088067(TYROBP)
VPC: 102525607(TYROBP)
BACU: 102998363(TYROBP)
BMUS: 118884894
LVE: 103077346(TYROBP)
OOR: 101286938(TYROBP)
DLE: 111181214(TYROBP)
PCAD: 102990043(TYROBP)
PSIU: 116744636(TYROBP)
NASI: 112392300(TYROBP)
ECB: 100051740(TYROBP)
EPZ: 103566802(TYROBP)
EAI: 106829262
MYB: 102240204(TYROBP)
MYD: 102763215(TYROBP)
MMYO: 118674665
MLF: 102417853(TYROBP)
PKL: 118720539
EFUS: 103284524(TYROBP)
MNA: 107543457(TYROBP)
DRO: 112320205(TYROBP)
SHON: 118982517
AJM: 119044197
PDIC: 114511370
PHAS: 123823829
MMF: 118638652
PPAM: 129083106(TYROBP)
HAI: 109372063(TYROBP)
RFQ: 117034989(TYROBP)
PALE: 102895208(TYROBP)
PGIG: 120592414
PVP: 105306662(TYROBP)
RAY: 107497638(TYROBP)
MJV: 108401515
TOD: 119250245(TYROBP)
SARA: 101541483(TYROBP)
SETR: 126027678(TYROBP)
LAV: 100658725(TYROBP)
TMU: 101346535
ETF: 101660836
DNM: 101421425(TYROBP)
MDO: 100016660(TYROBP)
GAS: 123243036
SHR: 100922718(TYROBP)
AFZ: 127556099
PCW: 110201931(TYROBP)
PRUF: 121351259
OMA: 130262908(TYROBP)
PHI: 106628945(TYROBP)
ZLE: 135441963(TYROBP)
SHAB: 115603376(TYROBP)
ASN: 102386909(TYROBP)
AMJ: 102569196(TYROBP) 109284081
PSS: 102448120(TYROBP)
CCAY: 125625996
DCC: 119847829
CPIC: 101933788
CABI: 116833668(TYROBP)
MRV: 120390457
ACS: 103279892(tyrobp)
ASAO: 132781830(TYROBP)
PVT: 110069845(TYROBP)
SUND: 121916068
PBI: 103064640(TYROBP)
PMUR: 107288360(TYROBP)
CTIG: 120300150
TSR: 106553566(TYROBP)
PGUT: 117669232(TYROBP)
APRI: 131204753(TYROBP)
PTEX: 113437412(TYROBP)
NSS: 113428813(TYROBP)
VKO: 123025938
PMUA: 114602997(TYROBP)
PRAF: 128418572(TYROBP)
ZVI: 118087936(TYROBP)
HCG: 128333120(TYROBP)
GJA: 107111385(TYROBP)
STOW: 125435442
EMC: 129343469(TYROBP)
XLA: 100158457(tyrobp.S) 108696884(tyrobp.L)
XTR: 100493958(tyrobp)
RTEM: 120916227
BBUF: 120985858
BGAR: 122929109
MUO: 115476361
GSH: 117345586
DRE: 100101461(tyrobp)
PTET: 122360717
LROH: 127178288(tyrobp)
OMC: 131522111(tyrobp)
PPRM: 120484245
RKG: 130101904(tyrobp)
MAMB: 125244155
CIDE: 127496692
TROS: 130558624(tyrobp)
TDW: 130432577(tyrobp)
MANU: 129448734(tyrobp)
IPU: 100305014(tyrobp)
IFU: 128606302(tyrobp)
PHYP: 113526874
SMEO: 124384930
TFD: 113644442
TVC: 132846251(tyrobp)
TRN: 134310372(tyrobp)
AMEX: 111193400
CMAO: 118824010
EEE: 113575663(tyrobp)
CHAR: 105891757
TRU: 105416718(tyrobp)
TFS: 130532674(tyrobp)
LCO: 104925503(tyrobp)
NCC: 104961399(tyrobp)
TBEN: 117480468(tyrobp)
CGOB: 115021561(tyrobp)
PGEO: 117460902(tyrobp)
GACU: 117554016(tyrobp)
EMAC: 134861798(tyrobp)
ELY: 117266117(tyrobp)
EFO: 125893223
SLUC: 116049361
ECRA: 117946826(tyrobp)
ESP: 116691074(tyrobp)
PFLV: 114557714(tyrobp)
GAT: 120810609
PPUG: 119197860
AFB: 129110171(tyrobp)
CLUM: 117745560(tyrobp)
PSWI: 130187909(tyrobp)
MSAM: 119897786
SCHU: 122881415
CUD: 121514138
ALAT: 119006419
MZE: 105941421(tyrobp)
ONL: 100709903(tyrobp)
OAU: 116319809
OLA: 105355915(tyrobp)
OML: 112144086
CSAI: 133440960(tyrobp)
XMA: 102234087(tyrobp)
XCO: 114139444(tyrobp)
XHE: 116715383(tyrobp)
PRET: 103478534(tyrobp)
PFOR: 103143088(tyrobp)
PLAI: 106945859(tyrobp)
PMEI: 106927174(tyrobp)
GAF: 122831100
PPRL: 129371381(tyrobp)
CVG: 107102530(tyrobp)
CTUL: 119772805
GMU: 124865680
NFU: 107378665(tyrobp)
KMR: 108241983
ALIM: 106517720(tyrobp)
NWH: 119410130
AOCE: 111577069(tyrobp)
MCEP: 125015920
CSEM: 103388552(tyrobp)
POV: 109633151(tyrobp)
SSEN: 122775025
HHIP: 117776687(tyrobp)
HSP: 118113950
PPLT: 128449633(tyrobp)
SMAU: 118302829
LCF: 108890871
SDU: 111234062(tyrobp)
SLAL: 111664897(tyrobp)
XGL: 120784599
HCQ: 109517600(tyrobp)
SSCV: 125975606
SBIA: 133501004(tyrobp)
PEE: 133401756(tyrobp)
PTAO: 133479410(tyrobp)
BPEC: 110171855(tyrobp)
MALB: 109971709(tyrobp)
BSPL: 114843426(tyrobp)
SJO: 128366562(tyrobp)
OTW: 112244873
OMY: 100653461(tyrobp)
OGO: 124005500
ONE: 115102075
OKI: 109901600
OKE: 118366560(tyrobp)
ELS: 105019129(tyrobp)
SFM: 108930320(tyrobp)
PKI: 111855359(tyrobp)
AANG: 118207017(tyrobp)
LOC: 107075408
PSPA: 121298856
PSEX: 120541716
PMAX: 117339274
 » show all
Reference
PMID:9490415
  Authors
Lanier LL, Corliss BC, Wu J, Leong C, Phillips JH
  Title
Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells.
  Journal
Nature 391:703-7 (1998)
DOI:10.1038/35642
  Sequence
[hsa:7305]

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