KEGG   ORTHOLOGY: K08046
Entry
K08046                      KO                                     
Symbol
ADCY6
Name
adenylate cyclase 6 [EC:4.6.1.1]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map01522  Endocrine resistance
map04015  Rap1 signaling pathway
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04072  Phospholipase D signaling pathway
map04114  Oocyte meiosis
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04371  Apelin signaling pathway
map04540  Gap junction
map04611  Platelet activation
map04713  Circadian entrainment
map04714  Thermogenesis
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04727  GABAergic synapse
map04742  Taste transduction
map04750  Inflammatory mediator regulation of TRP channels
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04913  Ovarian steroidogenesis
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04916  Melanogenesis
map04918  Thyroid hormone synthesis
map04921  Oxytocin signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04924  Renin secretion
map04925  Aldosterone synthesis and secretion
map04926  Relaxin signaling pathway
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04961  Endocrine and other factor-regulated calcium reabsorption
map04962  Vasopressin-regulated water reabsorption
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map04976  Bile secretion
map05032  Morphine addiction
map05163  Human cytomegalovirus infection
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05207  Chemical carcinogenesis - receptor activation
map05414  Dilated cardiomyopathy
Disease
H00865  Lethal congenital contractural syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K08046  ADCY6; adenylate cyclase 6
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04371 Apelin signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04072 Phospholipase D signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04024 cAMP signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04022 cGMP-PKG signaling pathway
    K08046  ADCY6; adenylate cyclase 6
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K08046  ADCY6; adenylate cyclase 6
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K08046  ADCY6; adenylate cyclase 6
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K08046  ADCY6; adenylate cyclase 6
   04062 Chemokine signaling pathway
    K08046  ADCY6; adenylate cyclase 6
  09152 Endocrine system
   04911 Insulin secretion
    K08046  ADCY6; adenylate cyclase 6
   04923 Regulation of lipolysis in adipocytes
    K08046  ADCY6; adenylate cyclase 6
   04912 GnRH signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04913 Ovarian steroidogenesis
    K08046  ADCY6; adenylate cyclase 6
   04915 Estrogen signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04914 Progesterone-mediated oocyte maturation
    K08046  ADCY6; adenylate cyclase 6
   04921 Oxytocin signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04926 Relaxin signaling pathway
    K08046  ADCY6; adenylate cyclase 6
   04935 Growth hormone synthesis, secretion and action
    K08046  ADCY6; adenylate cyclase 6
   04918 Thyroid hormone synthesis
    K08046  ADCY6; adenylate cyclase 6
   04928 Parathyroid hormone synthesis, secretion and action
    K08046  ADCY6; adenylate cyclase 6
   04916 Melanogenesis
    K08046  ADCY6; adenylate cyclase 6
   04924 Renin secretion
    K08046  ADCY6; adenylate cyclase 6
   04925 Aldosterone synthesis and secretion
    K08046  ADCY6; adenylate cyclase 6
   04927 Cortisol synthesis and secretion
    K08046  ADCY6; adenylate cyclase 6
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08046  ADCY6; adenylate cyclase 6
   04270 Vascular smooth muscle contraction
    K08046  ADCY6; adenylate cyclase 6
  09154 Digestive system
   04970 Salivary secretion
    K08046  ADCY6; adenylate cyclase 6
   04971 Gastric acid secretion
    K08046  ADCY6; adenylate cyclase 6
   04972 Pancreatic secretion
    K08046  ADCY6; adenylate cyclase 6
   04976 Bile secretion
    K08046  ADCY6; adenylate cyclase 6
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    K08046  ADCY6; adenylate cyclase 6
   04961 Endocrine and other factor-regulated calcium reabsorption
    K08046  ADCY6; adenylate cyclase 6
  09156 Nervous system
   04724 Glutamatergic synapse
    K08046  ADCY6; adenylate cyclase 6
   04727 GABAergic synapse
    K08046  ADCY6; adenylate cyclase 6
   04725 Cholinergic synapse
    K08046  ADCY6; adenylate cyclase 6
   04723 Retrograde endocannabinoid signaling
    K08046  ADCY6; adenylate cyclase 6
  09157 Sensory system
   04742 Taste transduction
    K08046  ADCY6; adenylate cyclase 6
   04750 Inflammatory mediator regulation of TRP channels
    K08046  ADCY6; adenylate cyclase 6
  09149 Aging
   04211 Longevity regulating pathway
    K08046  ADCY6; adenylate cyclase 6
   04213 Longevity regulating pathway - multiple species
    K08046  ADCY6; adenylate cyclase 6
  09159 Environmental adaptation
   04713 Circadian entrainment
    K08046  ADCY6; adenylate cyclase 6
   04714 Thermogenesis
    K08046  ADCY6; adenylate cyclase 6
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08046  ADCY6; adenylate cyclase 6
   05207 Chemical carcinogenesis - receptor activation
    K08046  ADCY6; adenylate cyclase 6
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K08046  ADCY6; adenylate cyclase 6
   05163 Human cytomegalovirus infection
    K08046  ADCY6; adenylate cyclase 6
  09165 Substance dependence
   05032 Morphine addiction
    K08046  ADCY6; adenylate cyclase 6
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    K08046  ADCY6; adenylate cyclase 6
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K08046  ADCY6; adenylate cyclase 6
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K08046  ADCY6; adenylate cyclase 6
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08046  ADCY6; adenylate cyclase 6
Other DBs
RN: R00089 R00434
GO: 0004016
Genes
HSA: 112(ADCY6)
PTR: 451866(ADCY6)
PPS: 100991116(ADCY6)
GGO: 101139873(ADCY6)
PON: 100438178(ADCY6)
NLE: 100589304(ADCY6)
MCC: 707978(ADCY6)
MCF: 102116122(ADCY6)
CSAB: 103238242(ADCY6)
CATY: 105580404(ADCY6)
PANU: 101008785(ADCY6)
TGE: 112635149(ADCY6)
RRO: 104654871(ADCY6)
RBB: 108543933(ADCY6)
TFN: 117090196(ADCY6)
PTEH: 111542054(ADCY6)
CJC: 100406617(ADCY6)
SBQ: 101037803(ADCY6)
CSYR: 103273462(ADCY6)
MMUR: 105867497(ADCY6)
OGA: 100963748(ADCY6)
MMU: 11512(Adcy6)
MCAL: 110310126(Adcy6)
MPAH: 110334500(Adcy6)
RNO: 25289(Adcy6)
MCOC: 116079067(Adcy6)
CGE: 100768368(Adcy6)
PLEU: 114708522(Adcy6)
NGI: 103750558(Adcy6)
HGL: 101698189(Adcy6)
CPOC: 100731224(Adcy6)
CCAN: 109686365(Adcy6)
DORD: 105987548(Adcy6)
DSP: 122106258(Adcy6)
NCAR: 124983776
OCU: 100354934(ADCY6)
OPI: 101528764(ADCY6)
TUP: 102468478(ADCY6)
CFA: 477625(ADCY6)
VVP: 112921089(ADCY6)
VLG: 121479760(ADCY6)
AML: 100476922(ADCY6)
UMR: 103675618(ADCY6)
UAH: 113257671(ADCY6)
UAR: 123794794(ADCY6)
ELK: 111157825
LLV: 125106490
MPUF: 101676713(ADCY6)
ORO: 101373816(ADCY6)
EJU: 114225777(ADCY6)
ZCA: 113922228(ADCY6)
MLX: 118008901(ADCY6)
FCA: 101091211(ADCY6)
PYU: 121038647(ADCY6)
PBG: 122472335(ADCY6)
PTG: 102949044(ADCY6)
PPAD: 109249043(ADCY6)
AJU: 106969297(ADCY6)
HHV: 120223032(ADCY6)
BTA: 509936(ADCY6)
BOM: 102265325(ADCY6)
BIU: 109559159(ADCY6)
BBUB: 102407637(ADCY6)
CHX: 102169557(ADCY6)
OAS: 101105735(ADCY6)
CCAD: 122427399(ADCY6)
SSC: 100522613(ADCY6)
CFR: 102519611(ADCY6)
CBAI: 105076187(ADCY6)
CDK: 105103816(ADCY6)
VPC: 102532587(ADCY6)
BACU: 103014094(ADCY6)
LVE: 103075153(ADCY6)
OOR: 101273023(ADCY6)
DLE: 111174035(ADCY6)
PCAD: 102986152(ADCY6)
PSIU: 116760787(ADCY6)
ECB: 100051295(ADCY6)
EPZ: 103563634(ADCY6)
EAI: 106836825(ADCY6)
MYB: 102248773(ADCY6)
MYD: 102766123(ADCY6)
MMYO: 118650262(ADCY6)
MLF: 102433159(ADCY6)
MNA: 107528232(ADCY6)
PKL: 118730217(ADCY6)
HAI: 109393238(ADCY6)
DRO: 112318673(ADCY6)
SHON: 118976509(ADCY6)
AJM: 119042160(ADCY6)
PDIC: 114512738(ADCY6)
PHAS: 123812947(ADCY6)
MMF: 118623920(ADCY6)
RFQ: 117028303(ADCY6)
PALE: 102890588(ADCY6)
PGIG: 120618216(ADCY6)
PVP: 105297518(ADCY6)
RAY: 107514224(ADCY6)
MJV: 108383520(ADCY6)
TOD: 119247875(ADCY6)
SARA: 101549131(ADCY6)
LAV: 100653532(ADCY6)
TMU: 101349243
DNM: 101442950(ADCY6)
GAS: 123250524(ADCY6)
SHR: 100932634(ADCY6)
PCW: 110201474(ADCY6)
OAA: 100081118(ADCY6)
GGA: 107050028
CJO: 107307087(ADCY6)
AFUL: 116499930(ADCY6)
TGU: 100223723(ADCY6)
LSR: 110480398(ADCY6)
SCAN: 103824610(ADCY6)
PMOA: 120499475(ADCY6)
OTC: 121334293(ADCY6)
PRUF: 121356310(ADCY6)
GFR: 102033025(ADCY6)
FAB: 101810909(ADCY6)
PHI: 102101002(ADCY6)
PMAJ: 107198603(ADCY6)
CCAE: 111940536(ADCY6)
ETL: 114071073
ZAB: 102068664(ADCY6)
FPG: 101916278(ADCY6)
FCH: 102050328(ADCY6)
CLV: 102092552(ADCY6)
NNI: 104019883(ADCY6)
TALA: 116960680(ADCY6)
ACHC: 115351035(ADCY6)
AROW: 112975226(ADCY6)
NPD: 112950312(ADCY6)
ASN: 102388125(ADCY6)
AMJ: 102573402(ADCY6)
CPOO: 109324447(ADCY6)
PSS: 102448834(ADCY6)
CMY: 102942183(ADCY6)
CPIC: 101948443(ADCY6)
TST: 117889271(ADCY6)
CABI: 116827794(ADCY6)
MRV: 120391118(ADCY6)
ACS: 100558069(adcy6)
PVT: 110074939(ADCY6)
SUND: 121921728(ADCY6)
PBI: 103050190(ADCY6)
PMUR: 107290979
TSR: 106539925
PGUT: 117662735(ADCY6)
VKO: 123019207(ADCY6)
PMUA: 114592965(ADCY6)
ZVI: 118077506(ADCY6)
GJA: 107120916(ADCY6)
XLA: 108708542(adcy6.L) 414728(adcy6.S)
XTR: 100493933(adcy6)
NPR: 108802250
RTEM: 120929589(ADCY6)
BBUF: 120995950(ADCY6)
BGAR: 122931129(ADCY6)
DRE: 560807(adcy6b) 570652(adcy6a)
PPRM: 120463384(adcy6b) 120488223(adcy6a)
IPU: 108276068(adcy6b)
PHYP: 113530428(adcy6)
TFD: 113658129(adcy6b)
EEE: 113583096(adcy6) 113591158
LCO: 104919645(adcy6) 104933400
CGOB: 115010615 115010702(adcy6)
ELY: 117258192(adcy6b) 117258226
PLEP: 121946801
ECRA: 117947096 117947753(adcy6b)
PFLV: 114558670(adcy6) 114558853
MZE: 101473262 101483853(adcy6)
ONL: 100702460 100704485(adcy6)
OAU: 116310917 116325822(adcy6b)
OLA: 101158108(adcy6) 101169035
XMA: 102232614(adcy6) 102235040
XHE: 116726440(adcy6) 116726867
PRET: 103467316 103467625(adcy6)
NFU: 107390847 107391215(adcy6)
CSEM: 103384589 103385410(adcy6)
LCF: 108876515 108900204(adcy6)
SLAL: 111670684 111671536(adcy6)
BPEC: 110164760(adcy6) 110164822
MALB: 109966043(adcy6) 109968886
SFM: 108918490(adcy6) 108939304
PKI: 111837572(adcy6)
AANG: 118208186
LOC: 102693411(adcy6)
PSPA: 121309011(adcy6a)
LCM: 102366154(ADCY6)
AGIF: 122847527
CLEC: 106671898
NLU: 111044161
PCHN: 125032896
PCLA: 123756565
CRG: 105346394
ATEN: 116306816
XEN: 124439835
 » show all
Reference
  Authors
Wicker R, Catalan AG, Cailleux A, Starenki D, Stengel D, Sarasin A, Suarez HG
  Title
Cloning and expression of human adenylyl cyclase type VI in normal thyroid tissues.
  Journal
Biochim Biophys Acta 1493:279-83 (2000)
DOI:10.1016/S0167-4781(00)00187-1
  Sequence
[hsa:112]
Reference
  Authors
Ding Q, Gros R, Gray ID, Taussig R, Ferguson SS, Feldman RD
  Title
Raf kinase activation of adenylyl cyclases: isoform-selective regulation.
  Journal
Mol Pharmacol 66:921-8 (2004)
DOI:10.1124/mol.66.4.921

DBGET integrated database retrieval system