KEGG ORTHOLOGY: K08080

ORTHOLOGY: K08080

Entry

K08080                      KO

Symbol

CMAH

Name

CMP-N-acetylneuraminate monooxygenase [EC:1.14.18.2]

Pathway

map00541

Biosynthesis of various nucleotide sugars

map01100

Metabolic pathways

map01250

Biosynthesis of nucleotide sugars

Module

M00955

CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc

Reaction

R01115

CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating)

R01803

N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    K08080  CMAH; CMP-N-acetylneuraminate monooxygenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.18  With another compound as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.18.2  CMP-N-acetylneuraminate monooxygenase
     K08080  CMAH; CMP-N-acetylneuraminate monooxygenase

Other DBs

GO:

0030338

Genes

PTR:	450121(CMAH)

PPS:	100978297(CMAH)

GGO:	101153123(CMAH)

PON:	100450703(CMAH)

PPYG:

NLE:

HMH:

SSYN:

MCC:	574186(CMAH)

MCF:

MTHB:

MNI:

CSAB:

CATY:

PANU:

TGE:

MLEU:

RRO:

RBB:

TFN:

PTEH:

CANG:

CSYR:

MMUR:

LCAT:

PCOQ:

OGA:

MMU:	12763(Cmah)

MCAL:

110307606

MPAH:

110333859

RNO:	361245(Cmahp)

MCOC:

116081601

ANU:	117712754 117713908

ASYL:

127664500

MUN:

110551070

CGE:	100689391(Cmah)

MAUA:

PROB:

PLEU:

MORG:

MFOT:

AAMP:

NGI:

HGL:

CPOC:

CCAN:

DORD:

DSP:

DMER:

PLOP:

NCAR:

MMMA:

ITI:

OCU:

OPI:

TUP:

GVR:

CFA:

CLUD:

VVP:

VLG:

NPO:

AML:

UMR:

UAH:

UAR:

FCA:	100750220(CMAH)

PYU:

PCOO:

PBG:

PVIV:

LRUF:

LGF:

AJU:

PTG:

PPAD:

PUC:

PLEZ:

HHV:

BTA:	537017(CMAH)

BOM:

BIU:

BBUB:

BBIS:

CHX:	102189920 108635102

OAS:

BTAX:

CSUM:

ODA:

CCAD:

MREE:

OVR:

MBEZ:

SSC:	396918(CMAH)

CFR:

102517286

CBAI:

105084186

CDK:

105089138

VPC:	102537513 102543121

BACU:

BMUS:

LVE:

OOR:

LALB:

GMF:

DDP:

DLE:

PCAD:

PSIU:

PPHC:

NASI:

ECB:

EPZ:

EAI:

DRO:

SHON:

AJM:

PDIC:

PHAS:

PPAM:

PALE:

PGIG:

PVP:

RAY:

MJV:

TOD:

SARA:

SFUM:

SETR:

LAV:

TMU:

ETF:

DNM:

MDO:

GAS:

SHR:

AFZ:

PCW:

TVP:

PBRV:

MLAO:

ACS:

ASAO:

PVT:

SUND:

VKO:

PMUA:

PRAF:

HCG:

STOW:

EMC:

XLA:	379989(cmahp.L)

XTR:	100216283(cmahp)

NPR:

108786896

RTEM:

120940782 120940783

ACAT:

141144988 141144989 141145914

BBUF:

121002189 121002190

BGAR:

122931557 122938794 122939448

DTC:

PWL:

MUO:

GSH:

DRE:	431739(cmah)

SRX:	107707959 107729160

SANH:

107656456 107658750

SGH:	107555874 107590555

CCAR:

109063653(cmah) 109102374

CAUA:

113048495 113059734

CGIB:

127956500 127979083

PTET:

122342737(cmah)

LROH:

127163864 127163865

GRF:	141333248 141333257

OMC:	131538560(cmah)

PPRM:

120471052(cmah)

RKG:	130080104 130080105

MAMB:

125244634(cmah)

CIDE:

127511545 127511546

CERY:

137024198(cmah)

MASI:

127435451 127436525

TROS:

130547845(cmah) 130550021

TDW:	130421229(cmah)

MANU:

129432719 129432720(cmah) 141349227

PDAB:

135758750 135758752

IPU:	108279485(cmah)

PHYP:

113535028

CGAR:

128534230(cmah)

TRN:	134325310(cmah)

CMAO:

118812184(cmah)

SPIL:

134061667 134061668 134061801 134061802 134062096

TRU:	115246491 115246687 777967

TFS:	130520803(cmah)

TNG:	GSTEN00005973G001

LCO:

109138214

TBEN:

117483221(cmah)

CGOB:

115028374

PGEO:

117439043(cmah)

GACU:

117551232 117551235

EMAC:

134879354(cmah)

EFO:	125883209(cmah)

PLEP:

121961711(cmah)

SLUC:

116054709(cmah)

ECRA:

117940022(cmah)

ESP:

116686165

PFLV:

114549852

GAT:	120817747 120817945

PPUG:

119211029 134111793 134111825(cmah)

AFB:	129112854(cmah)

CLUM:

117726052(cmah)

PSWI:

130191125(cmah)

CANA:

137791845(cmah)

MSAM:

119918133 119918134 119918437

SCHU:

122871635(cmah)

CUD:	121505194(cmah)

SPUL:

138599575(cmah)

LMIX:

132956293(cmah) 132956309

ALAT:

119032359(cmah)

ASTR:

137589447(cmah)

MZE:	101466628 101476433

ONL:

100691852

OAU:	116312123 116331606

OML:	112140010(cmah)

XMA:	102224063 102230600

XCO:	114161041 114161257

XHE:

PRET:

PLAI:

PMEI:

PPRL:

129376234(cmah)

CVG:

107099834

CTUL:

119798180(cmah)

GMU:	124883105 124883407

NFU:

107374035

ALIM:

106522556

NWH:	119428047(cmah)

EJA:	138202467(cmah)

BFRE:

138629474(cmah)

BPEC:

110172371

ENY:	140367658(cmah)

BSPL:

114862045(cmah)

SJO:	128385364(cmah)

SSCO:

134004175(cmah)

SASA:

106604887 106609768 106609788

STRU:

115180355 115199149

OTW:	112214917(cmah) 121845873

OMY:	110499771 110499779 110499782 110500969 110500972 110518324

OGO:	123994502(cmah)

ONE:

115125015

OKI:	109876981 109876982 116363549

OKE:

118370425

OMM:	135515643(cmah)

OCLA:

139392962 139399908 139404540 139404556 139404557

SALP:

112077024

SNH:	120049174(cmah)

CCLU:

121543913

SFM:

108936309

PKI:

111856660

AANG:

118220432 118221204 118221926 118221927

AROT:

135249124(cmah)

CCOG:

133111804(cmah)

LOC:

102695321

PSPA:

121320871(cmah)

ARUT:

117973014

LCM:

102366592

BFO:	118410108 118418888 118420159 118424237 118430247

BBEL:

109465764 109470655 109473073 109477656 109487371

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

140144084 140150208 140150916 140151293 140163179 140163182

AJC:

117102736

SKO:

100367349

PFLL:

139115580 139116902 139134685 139134859 139138234

OTA:	OT_ostta19g00610

MIS:	MICPUN_53233

PMOB:

HG718_03810

PPHR:

APZ00_22700

HFE:	HFELIS_01840 HFELIS_09990

HBI:	HBZC1_05440

HCM:

HCD_04105

HHM:	BN341_7020

HBL:	XJ32_10870

HAIL:

ASB7_01970

LYS:	LBYS11_03285

MPRO:

BJP34_15965

NKR:	NKOR_00480

» show all

Reference

PMID:7608218

Authors

Kawano T, Koyama S, Takematsu H, Kozutsumi Y, Kawasaki H, Kawashima S, Kawasaki T, Suzuki A

Title

Molecular cloning of cytidine monophospho-N-acetylneuraminic acid hydroxylase. Regulation of species- and tissue-specific expression of N-glycolylneuraminic acid.

Journal

J Biol Chem 270:16458-63 (1995)
DOI:10.1074/jbc.270.27.16458

Sequence

[mmu:12763]

All links

Ontology (1)   
   GO (1)   
Gene (1462)   
   MGENES (1002)   
   RefGene (455)   
   OC (5)   
All databases (1463)   

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