KEGG   ORTHOLOGY: K08269Help
Entry
K08269                      KO                                     

Name
ULK2, ATG1
Definition
serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
Pathway
ko04136  Autophagy - other
ko04138  Autophagy - yeast
ko04139  Mitophagy - yeast
ko04140  Autophagy - animal
ko04150  mTOR signaling pathway
ko04212  Longevity regulating pathway - worm
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04150 mTOR signaling pathway
    K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2
   04138 Autophagy - yeast
    K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2
   04136 Autophagy - other eukaryotes
    K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2
   04139 Mitophagy - yeast
    K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2
 Organismal Systems
  Aging
   04212 Longevity regulating pathway - worm
    K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  ULK family [OT]
   K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2
Membrane trafficking [BR:ko04131]
 Autophagy
  Autophagosome formation proteins
   Atg1 complex
    K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2
BRITE hierarchy
Other DBs
COG: COG0515
Genes
HSA: 9706(ULK2)
PTR: 454507(ULK2)
PPS: 100971519(ULK2)
GGO: 101133270(ULK2)
PON: 100447224(ULK2)
NLE: 100595140(ULK2)
MCC: 710708(ULK2)
MCF: 101925926(ULK2)
CSAB: 103242520(ULK2)
RRO: 104663276(ULK2) 104680258
RBB: 108521945(ULK2) 108540897
CJC: 100386171(ULK2)
SBQ: 101047479(ULK2)
MMU: 29869(Ulk2)
RNO: 303206(Ulk2)
CGE: 100759097(Ulk2)
NGI: 103727512(Ulk2)
HGL: 101712848(Ulk2) 101714976
CCAN: 109687736 109687740(Ulk2)
OCU: 100353118(ULK2)
TUP: 102502826(ULK2)
CFA: 489525(ULK2)
AML: 100484867(ULK2)
UMR: 103658551(ULK2)
ORO: 101364115(ULK2)
FCA: 101083981(ULK2)
PTG: 102952805(ULK2)
AJU: 106981411(ULK2)
BTA: 618601(ULK2)
BOM: 102268847(ULK2)
BIU: 109573261(ULK2)
PHD: 102330716(ULK2)
CHX: 102179415(ULK2)
OAS: 101108239(ULK2)
SSC: 100525780(ULK2)
CFR: 102516695(ULK2)
CDK: 105085092(ULK2)
BACU: 103000249(ULK2)
LVE: 103079233(ULK2)
OOR: 101285840(ULK2)
ECB: 100073154(ULK2)
EPZ: 103564269(ULK2)
EAI: 106838853(ULK2)
MYB: 102260328(ULK2)
MYD: 102774469(ULK2)
HAI: 109382195(ULK2)
RSS: 109461296(ULK2)
PALE: 102895828(ULK2)
LAV: 100658155(ULK2)
TMU: 101345383
MDO: 100019989(ULK2)
SHR: 100934448(ULK2)
OAA: 100077170(ULK2)
GGA: 417614(ULK2)
MGP: 100538803(ULK2)
CJO: 107322389(ULK2)
APLA: 101793905(ULK2)
ACYG: 106045818(ULK2)
TGU: 100218452(ULK2)
GFR: 102038744(ULK2)
FAB: 101817299(ULK2)
PHI: 102103867(ULK2)
PMAJ: 107212703(ULK2)
CCW: 104691021(ULK2)
FPG: 101910885(ULK2)
FCH: 102059967(ULK2)
CLV: 102084835(ULK2)
EGZ: 104121896(ULK2)
AAM: 106496045(ULK2)
ASN: 102371419(ULK2)
AMJ: 102567608(ULK2)
PSS: 102444812(ULK2)
CMY: 102934546(ULK2)
CPIC: 101940837(ULK2)
ACS: 100562716(ulk2)
PVT: 110087382(ULK2)
PBI: 103061964(ULK2)
GJA: 107111226(ULK2) 107124997
XTR: 100487396(ulk2)
NPR: 108791087(ULK2)
DRE: 100329702(ulk2)
SGH: 107586251(ulk2) 107597580
IPU: 108277484(ulk2)
AMEX: 103026407(ulk2)
TRU: 101075494(ulk2)
LCO: 104930671(ulk2) 109136632
MZE: 101479468(ulk2)
OLA: 101160680
XMA: 102233777(ulk2)
PRET: 103474342(ulk2)
NFU: 107373219(ulk2) 107380736
CSEM: 103377644(ulk2)
LCF: 108900310(ulk2)
BPEC: 110171357(ulk2)
ELS: 105023805(ulk2)
SFM: 108921163 108932341(ulk2)
LCM: 102355618(ULK2)
CMK: 103186923(ulk2)
CIN: 100175789
SPU: 594031
DME: Dmel_CG10967(Atg1)
DSI: Dsimw501_GD12695(Dsim_GD12695)
MDE: 101894134
AAG: 5579092
AME: 552571(Atg1)
BIM: 100746999
BTER: 100644361
SOC: 105207578
AEC: 105144246
ACEP: 105619240
PBAR: 105432181
HST: 105191916
CFO: 105257917
LHU: 105673062
PGC: 109858413
NVI: 100123698
TCA: 659114
DPA: 109538950
NVL: 108558874
BMOR: 101745443
PMAC: 106717803
PRAP: 110995139
PXY: 105387493
API: 100159542
DNX: 107162961
ZNE: 110840817
FCD: 110850725
CEL: CELE_Y60A3A.1(unc-51)
CBR: CBG24635(Cbr-unc-51)
BMY: Bm1_44665
CRG: 105343707
MYI: 110461903
OBI: 106876056
EPA: 110246352
ADF: 107335367
HMG: 100212126
AQU: 100640446
THJ: 104823411
CIT: 102621459
GRA: 105780097
EGR: 104426428
GMX: 100791596
VRA: 106774258
CAM: 101509182
AIP: 107625614
LJA: Lj0g3v0250139.1(Lj0g3v0250139.1)
FVE: 101307421
PMUM: 103338827
MDM: 103450279
CSV: 101221608
CMO: 103486358
RCU: 8283884
JCU: 105646692
SLY: 101247744
SPEN: 107031744
SOT: 102591726
SIND: 105161588
BVG: 104893820
OSA: 9268534
OBR: 102705988
ATS: 109736584(LOC109736584) 109769705(LOC109769705)
EGU: 105056880
MUS: 103974431
ATR: 18436315
APRO: F751_0977
SCE: YGL180W(ATG1)
ERC: Ecym_8400
KMX: KLMA_30321(ATG1)
NCS: NCAS_0C04100(NCAS0C04100)
NDI: NDAI_0G03450(NDAI0G03450)
TPF: TPHA_0H00410(TPHA0H00410)
TBL: TBLA_0D02230(TBLA0D02230)
TDL: TDEL_0B04700(TDEL0B04700)
KAF: KAFR_0C03010(KAFR0C03010)
PIC: PICST_40055(ATG1)
CAUR: QG37_01881
SLB: AWJ20_1168(ATG1)
NCR: NCU00188(apg-1)
NTE: NEUTE1DRAFT100773(NEUTE1DRAFT_100773)
MGR: MGG_06393
MAJ: MAA_03501
CMT: CCM_07279
BFU: BCIN_07g00720(bpk3)
MBE: MBM_07709
ANI: AN1632.2
ANG: ANI_1_724184(An04g03950)
ABE: ARB_00361
TVE: TRV_04201
PTE: PTT_00529
SPO: SPCC63.08c(atg1)
CNE: CNL06100
CNB: CNBI0730
ABP: AGABI1DRAFT75792(AGABI1DRAFT_75792)
ABV: AGABI2DRAFT209416(AGABI2DRAFT_209416)
MGL: MGL_3059
DDI: DDB_G0292390(atg1)
DFA: DFA_01991 DFA_03609(atg1)
PTI: PHATRDRAFT_5526(hCDK6)
FCY: FRACYDRAFT_188113(hCDK6)
SPAR: SPRG_15046
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9224897
  Authors
Matsuura A, Tsukada M, Wada Y, Ohsumi Y
  Title
Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae.
  Journal
Gene 192:245-50 (1997)
DOI:10.1016/S0378-1119(97)00084-X
  Sequence
[sce:YGL180W]
Reference
  Authors
Tal R, Winter G, Ecker N, Klionsky DJ, Abeliovich H
  Title
Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival.
  Journal
J Biol Chem 282:5617-24 (2007)
DOI:10.1074/jbc.M605940200
  Sequence
[sce:YGL180W]
Reference
  Authors
Lee EJ, Tournier C
  Title
The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy.
  Journal
Autophagy 7:689-95 (2011)
DOI:10.4161/auto.7.7.15450
  Sequence
[mmu:29869]

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