KEGG ORTHOLOGY: K08370

ORTHOLOGY: K08370

Entry

K08370                      KO

Symbol

CYBRD1, Dcytb

Name

plasma membrane ascorbate-dependent reductase [EC:7.2.1.3]

Pathway

map04978

Mineral absorption

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    K08370  CYBRD1, Dcytb; plasma membrane ascorbate-dependent reductase
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K08370  CYBRD1, Dcytb; plasma membrane ascorbate-dependent reductase
Enzymes [BR:ko01000]
7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.1  Linked to oxidoreductase reactions
    7.2.1.3  ascorbate ferrireductase (transmembrane)
     K08370  CYBRD1, Dcytb; plasma membrane ascorbate-dependent reductase
Transporters [BR:ko02000]
Other transporters
  Transmembrane electron carriers
   K08370  CYBRD1, Dcytb; plasma membrane ascorbate-dependent reductase

Other DBs

TC:

5.B.2.1

Genes

HSA:	79901(CYBRD1)

PTR:	737081(CYBRD1)

PPS:

100972759

GGO:

101141704

PON:	100172640(CYBRD1)

NLE:

100593374

HMH:

116810669

MCC:	694818(CYBRD1)

MCF:

102120369

MTHB:

126932498

MNI:

105483245

CSAB:

103217305(CYBRD1)

CATY:

PANU:

TGE:

MLEU:

RRO:

RBB:

TFN:

PTEH:

CANG:

CJC:	100408533(CYBRD1)

SBQ:

CIMI:

CSYR:

MMUR:

LCAT:

PCOQ:

OGA:

MMU:	73649(Cybrd1)

MCAL:

110290000

MPAH:

110319194

RNO:	295669(Cybrd1)

MCOC:

ANU:

MUN:

CGE:

MAUA:

PROB:

PLEU:

MORG:

MFOT:

AAMP:

NGI:

HGL:

CPOC:

CCAN:

DORD:

DSP:

PLOP:

NCAR:

OCU:

OPI:

TUP:

GVR:

CFA:	478796(CYBRD1)

CLUD:

VVP:

VLG:

NPO:

AML:

UMR:

UAH:

UAR:

ELK:

LLV:

MPUF:

MNP:

MLK:

NVS:

ORO:

EJU:

ZCA:

MLX:

NSU:

LWW:

FCA:	101089456(CYBRD1)

PYU:

PCOO:

PBG:

PVIV:

LRUF:

PTG:

PPAD:

PUC:	125917098 125917922

AJU:

106988614

HHV:

120236394

BTA:	534257(CYBRD1)

BOM:

BIU:

BBUB:

BBIS:

CHX:

OAS:

BTAX:

ODA:

CCAD:

MBEZ:

SSC:	100144591(CYBRD1)

CFR:

CBAI:

CDK:

VPC:

BACU:

BMUS:

LVE:

OOR:

DLE:

PCAD:

PSIU:

NASI:

ECB:

EPZ:

EAI:

MYB:

MYD:

MMYO:

MLF:

PKL:

EFUS:

MNA:

DRO:

SHON:

AJM:

PDIC:

PHAS:

MMF:

PPAM:

HAI:

RFQ:

PALE:

PGIG:

PVP:

RAY:

MJV:

TOD:

SARA:

LAV:

TMU:

ETF:

DNM:

MDO:

GAS:

SHR:

AFZ:

PCW:

OAA:

GGA:	424152(CYBRD1)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

CATA:

AFUL:

TGU:

LSR:

SCAN:

PMOA:

OTC:

PRUF:

GFR:

FAB:

OMA:

PHI:

PMAJ:

CCAE:

CCW:

CBRC:

ZAB:

ACHL:

SVG:

MMEA:

HRT:

FPG:

FCH:

CLV:

EGZ:

NNI:

PCRI:

PLET:

EHS:

PCAO:

ACUN:

TALA:

PADL:

AFOR:

ACHC:

HALD:

HLE:

AGEN:

GCL:

CCRI:

CSTI:

CMAC:

MUI:

BREG:

FGA:

GSTE:

LDI:

MNB:

OHA:

NNT:

SHAB:

DPUB:

PGUU:

ACAR:

CPEA:

AVIT:

CVF:

RTD:

CUCA:

TEO:

BRHI:

AAM:

AROW:

NPD:

TGT:

DNE:

SCAM:

ASN:

AMJ:	102575142(CYBRD1)

CPOO:

GGN:

PSS:

CMY:

CCAY:

DCC:

CPIC:

TST:

CABI:

MRV:

ACS:

ASAO:

PVT:

SUND:

PBI:

PMUR:

CTIG:

TSR:

PGUT:

APRI:

PTEX:

NSS:

VKO:

PMUA:

PRAF:

ZVI:

HCG:

GJA:

STOW:

EMC:

XLA:	108702990(cybrd1.S) 445864(cybrd1.L)

XTR:	548408(cybrd1)

NPR:

RTEM:

BBUF:

BGAR:

MUO:

DRE:	552960(cybrd1)

SRX:

SANH:

SGH:

CCAR:

CAUA:

CGIB:

PTET:

LROH:

OMC:

PPRM:

RKG:

MAMB:

CIDE:

MASI:

TROS:

TDW:

MANU:

IPU:

IFU:

PHYP:

SMEO:

TFD:

TVC:

AMEX:

CMAO:

EEE:

CHAR:

TRU:

TFS:

TNG:	GSTEN00031422G001

LCO:

NCC:

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:	120833663 120833664

PPUG:

AFB:

CLUM:

PSWI:

MSAM:

SCHU:

CUD:	121520658 121522318

ALAT:

MZE:

ONL:

OAU:

OLA:

OML:

CSAI:

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

CVG:

CTUL:

GMU:

NFU:

KMR:

ALIM:

NWH:

AOCE:

MCEP:

POV:

SSEN:

HHIP:

HSP:

SMAU:

LCF:

SDU:

SLAL:

XGL:

HCQ:

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

MALB:

BSPL:

SJO:

SASA:

106581770(CYBR1) 106586222(CYBR1)

STRU:

115156023 115160755

OTW:	112225232 112236571

OMY:	110501459 110520104

OGO:	124043100 124043858

ONE:	115102115 115109066

OKI:	109866637 109871331

OKE:	118367078 118386038

SALP:

111959972 111975083

SNH:	120058248 120063828

CCLU:

SFM:

PKI:

AANG:

LOC:

PSPA:

ARUT:

PSEX:

LCM:

CMK:

RTP:

CPLA:

HOC:

LERI:

PMRN:

LRJ:

DMO:	Dmoj_GI19919

DAZ:

DNV:

DHE:

LSQ:

NVL:

Reference

PMID:11230685

Authors

McKie AT, Barrow D, Latunde-Dada GO, Rolfs A, Sager G, Mudaly E, Mudaly M, Richardson C, Barlow D, Bomford A, Peters TJ, Raja KB, Shirali S, Hediger MA, Farzaneh F, Simpson RJ

Title

An iron-regulated ferric reductase associated with the absorption of dietary iron.

Journal

Science 291:1755-9 (2001)
DOI:10.1126/science.1057206

Sequence

[mmu:73649]

Reference

PMID:12547225

Authors

Latunde-Dada GO, Van der Westhuizen J, Vulpe CD, Anderson GJ, Simpson RJ, McKie AT

Title

Molecular and functional roles of duodenal cytochrome B (Dcytb) in iron metabolism.

Journal

Blood Cells Mol Dis 29:356-60 (2002)
DOI:10.1006/bcmd.2002.0574

Reference

PMID:16286504

Authors

Mackenzie B, Garrick MD

Title

Iron Imports. II. Iron uptake at the apical membrane in the intestine.

Journal

Am J Physiol Gastrointest Liver Physiol 289:G981-6 (2005)
DOI:10.1152/ajpgi.00363.2005

All links

Ontology (4)   
   KEGG BRITE (3)   
   TC (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (722)   
   KEGG GENES (404)   
   KEGG MGENES (126)   
   RefGene (190)   
   OC (2)   
Literature (3)   
   PubMed (3)   
All databases (732)   

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