KEGG   ORTHOLOGY: K08525Help
Entry
K08525                      KO                                     

Name
RXRB, NR2B2
Definition
retinoid X receptor beta
Pathway
ko03320  PPAR signaling pathway
ko04659  Th17 cell differentiation
ko04919  Thyroid hormone signaling pathway
ko04920  Adipocytokine signaling pathway
ko04928  Parathyroid hormone synthesis, secretion and action
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05216  Thyroid cancer
ko05222  Small cell lung cancer
ko05223  Non-small cell lung cancer
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04659 Th17 cell differentiation
    K08525  RXRB, NR2B2; retinoid X receptor beta
  Endocrine system
   04920 Adipocytokine signaling pathway
    K08525  RXRB, NR2B2; retinoid X receptor beta
   03320 PPAR signaling pathway
    K08525  RXRB, NR2B2; retinoid X receptor beta
   04919 Thyroid hormone signaling pathway
    K08525  RXRB, NR2B2; retinoid X receptor beta
   04928 Parathyroid hormone synthesis, secretion and action
    K08525  RXRB, NR2B2; retinoid X receptor beta
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05202 Transcriptional misregulation in cancers
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05226 Gastric cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05216 Thyroid cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05222 Small cell lung cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
   05223 Non-small cell lung cancer
    K08525  RXRB, NR2B2; retinoid X receptor beta
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Zinc finger
   Cys4 hepatocyte nuclear factor 4-like
    K08525  RXRB, NR2B2; retinoid X receptor beta
Nuclear receptors [BR:ko03310]
 2. Hepatocyte nuclear factor 4 like
  2B. Retinoid X receptor (RXR)
   K08525  RXRB, NR2B2; retinoid X receptor beta
BRITE hierarchy
Other DBs
GO: 0004886
Genes
HSA: 6257(RXRB)
PTR: 462601(RXRB)
PPS: 100992933(RXRB)
GGO: 101143109(RXRB)
PON: 100460920(RXRB)
NLE: 100580742(RXRB)
MCC: 717368(RXRB)
MCF: 102132522(RXRB)
CSAB: 103221675(RXRB)
RRO: 104657982(RXRB)
RBB: 108540287(RXRB)
CJC: 100414004(RXRB)
SBQ: 101040304(RXRB)
MMU: 20182(Rxrb)
RNO: 361801(Rxrb)
CGE: 100759059(Rxrb)
NGI: 103739713(Rxrb)
HGL: 101723696(Rxrb)
CCAN: 109686703(Rxrb)
OCU: 100354287(RXRB)
TUP: 102495243(RXRB)
CFA: 481735(RXRB)
AML: 100475696(RXRB)
UMR: 103665560(RXRB)
ORO: 101373938(RXRB)
PTG: 102952674(RXRB)
AJU: 106976118(RXRB)
BTA: 504943(RXRB)
BOM: 102286075(RXRB)
BIU: 109576548(RXRB)
PHD: 102341105(RXRB)
CHX: 102189445(RXRB)
OAS: 101110798(RXRB)
SSC: 100156801(RXRB)
CFR: 102517692(RXRB)
CDK: 105101393(RXRB)
BACU: 103006710(RXRB)
LVE: 103087387(RXRB)
OOR: 101287304(RXRB)
ECB: 100061303(RXRB)
EPZ: 103541179(RXRB)
EAI: 106834605(RXRB)
MYB: 102247746(RXRB)
MYD: 102766946(RXRB)
HAI: 109392460(RXRB)
RSS: 109450925(RXRB)
PALE: 102888877(RXRB)
LAV: 100662699(RXRB)
TMU: 101349083
MDO: 100027006(RXRB)
SHR: 100914649(RXRB)
AAM: 106485616
ASN: 102369321(RXRB)
AMJ: 102561414(RXRB)
CMY: 102930075
CPIC: 101936256(RXRB)
ACS: 100554139
PVT: 110091139(RXRB)
PBI: 103055088(RXRB)
GJA: 107109601(RXRB)
XLA: 394278(rxrb.L) 398075(rxrb.S)
XTR: 548691(rxrb)
NPR: 108788389(RXRB)
DRE: 30530(rxrba)
SGH: 107566635
CCAR: 109087048
IPU: 108272672
AMEX: 103021434
TRU: 101065480(rxrb)
LCO: 104933394(rxrb)
NCC: 104957485(rxrb)
MZE: 101473908
OLA: 100125505
XMA: 102217951
PRET: 103472931
NFU: 107378676 107394848(rxrb)
CSEM: 103393870
LCF: 108886934
HCQ: 109514591
BPEC: 110173337
SASA: 106569952 106588394(RXRB)
ELS: 105005656(rxrb) 105018834
SFM: 108935649(rxrb)
LCM: 102350929
AQU: 100616090
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1310259
  Authors
Leid M, Kastner P, Lyons R, Nakshatri H, Saunders M, Zacharewski T, Chen JY, Staub A, Garnier JM, Mader S, et al.
  Title
Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.
  Journal
Cell 68:377-95 (1992)
DOI:10.1016/0092-8674(92)90478-U
  Sequence
[hsa:6257]
Reference
  Authors
Lefebvre P, Benomar Y, Staels B
  Title
Retinoid X receptors: common heterodimerization partners with distinct functions.
  Journal
Trends Endocrinol Metab 21:676-83 (2010)
DOI:10.1016/j.tem.2010.06.009

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