KEGG ORTHOLOGY: K08608

ORTHOLOGY: K08608

Entry

K08608                      KO

Symbol

ADAM19

Name

disintegrin and metalloproteinase domain-containing protein 19 [EC:3.4.24.-]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K08608  ADAM19; disintegrin and metalloproteinase domain-containing protein 19
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.-
     K08608  ADAM19; disintegrin and metalloproteinase domain-containing protein 19
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
  Family M12: astacin/adamalysin family
   K08608  ADAM19; disintegrin and metalloproteinase domain-containing protein 19

Genes

HSA:	8728(ADAM19)

PTR:	735763(ADAM19)

PPS:	100983987(ADAM19)

GGO:	101133651(ADAM19)

PON:	100461103(ADAM19)

NLE:	100599590(ADAM19)

HMH:	116471769(ADAM19)

MCC:	715164(ADAM19)

MCF:	102143685(ADAM19)

MTHB:

126956720

MNI:	105482367(ADAM19)

CSAB:

103244869(ADAM19)

CATY:

105581561(ADAM19)

PANU:

101016427(ADAM19)

TGE:	112626880(ADAM19)

MLEU:

105529538(ADAM19)

RRO:	104662399(ADAM19)

RBB:	108518344(ADAM19)

TFN:	117065558(ADAM19)

PTEH:

111547164(ADAM19)

CANG:

105515768(ADAM19)

CJC:	100389375(ADAM19)

SBQ:	101027897(ADAM19)

CIMI:

108295041(ADAM19)

CSYR:

103257762(ADAM19)

MMUR:

105880496(ADAM19)

LCAT:

123638019(ADAM19)

PCOQ:

105815231(ADAM19)

OGA:	100956329(ADAM19)

MMU:	11492(Adam19)

MCAL:

110305333(Adam19)

MPAH:

110331542(Adam19)

RNO:	303068(Adam19)

MCOC:

116079085(Adam19)

ANU:	117711168(Adam19)

MUN:

110557204

CGE:	100762809(Adam19)

MAUA:

101840268(Adam19)

PROB:

127219386(Adam19)

PLEU:

114704326

MORG:

121464044(Adam19)

MFOT:

126499450

AAMP:

119812224(Adam19)

NGI:	103745467(Adam19)

HGL:	101707880(Adam19)

CPOC:

100731212(Adam19)

CCAN:

109696232(Adam19)

DORD:

105996687(Adam19)

DSP:	122125037(Adam19)

PLOP:

125341820(Adam19)

NCAR:

124986897

OCU:

100352746

OPI:	101526974(ADAM19)

TUP:	102488935(ADAM19)

GVR:

103608233

CFA:	489156(ADAM19)

CLUD:

112651984(ADAM19)

VVP:	112928175(ADAM19)

VLG:	121487443(ADAM19)

NPO:	129509665(ADAM19)

AML:	100481400(ADAM19)

UMR:	103664801(ADAM19)

UAH:	113264021(ADAM19)

UAR:	123788541(ADAM19)

ELK:

111141010

LLV:

125099971

MPUF:

101680398(ADAM19)

NVS:	122893501(ADAM19)

ORO:	101381183(ADAM19)

EJU:	114211846(ADAM19)

ZCA:	113928961(ADAM19)

MLX:	118016039(ADAM19)

NSU:	110585355(ADAM19)

LWW:	102737157(ADAM19)

FCA:	101090741(ADAM19)

PYU:	121009895(ADAM19)

PCOO:

112860364(ADAM19)

PBG:	122493139(ADAM19)

LRUF:

124520803

PTG:	102956530(ADAM19)

PPAD:

109276021(ADAM19)

PUC:

125934494

AJU:

106967665

HHV:	120243323(ADAM19)

BTA:	510907(ADAM19)

BOM:	102269699(ADAM19)

BIU:	109562252(ADAM19)

BBUB:

102395395(ADAM19)

BBIS:

104999724(ADAM19)

CHX:	102178445(ADAM19)

OAS:	101113590(ADAM19)

BTAX:

128050769(ADAM19)

ODA:	120864385(ADAM19)

CCAD:

122439631(ADAM19)

MBEZ:

129558126(ADAM19)

SSC:	100521528(ADAM19)

CFR:	102511372(ADAM19)

CBAI:

105080930(ADAM19)

CDK:	105095138(ADAM19)

VPC:	102542568(ADAM19)

BACU:

103011553(ADAM19)

LVE:	103090957(ADAM19)

OOR:	101281853(ADAM19)

DLE:	111183159(ADAM19)

PCAD:

102996211(ADAM19)

PSIU:

116751628(ADAM19)

NASI:

112409810(ADAM19)

ECB:	100059871(ADAM19)

EPZ:	103547682(ADAM19)

EAI:	106832131(ADAM19)

MYB:	102250125(ADAM19)

MYD:	102755386(ADAM19)

MMYO:

118659146(ADAM19)

MLF:	102439964(ADAM19)

MNA:	107534436(ADAM19)

PKL:	118711724(ADAM19)

EFUS:

103291605(ADAM19)

HAI:	109388912(ADAM19)

DRO:	112319597(ADAM19)

SHON:

118986105(ADAM19)

AJM:	119054354(ADAM19)

PDIC:

114509866(ADAM19)

PHAS:

123808918(ADAM19)

MMF:	118644007(ADAM19)

RFQ:	117016720(ADAM19)

PALE:

102881517(ADAM19)

PGIG:

120613942(ADAM19)

PVP:	105289953(ADAM19)

RAY:	107521899(ADAM19)

MJV:	108407724(ADAM19)

TOD:	119236358(ADAM19)

SARA:

101545230(ADAM19)

LAV:	100675151(ADAM19)

TMU:

101346807

ETF:	101647785(ADAM19)

DNM:	101438382(ADAM19)

MDO:	100025742(ADAM33) 100030114(ADAM19)

GAS:	123233805(ADAM19) 123252491(ADAM33)

SHR:	100922668(ADAM33) 100931448(ADAM19)

AFZ:	127542035 127550136

PCW:	110199709 110221047(ADAM33)

OAA:	100075748(ADAM19)

GGA:	416244(ADAM19) 422948(ADAM33)

PCOC:

116225663(ADAM33) 116232106(ADAM19)

MGP:	100541775(ADAM19) 100543150(ADAM33)

CJO:	107314102(ADAM33) 107320409(ADAM19)

TPAI:

128080039(ADAM33) 128081423(ADAM19)

LMUT:

125692719(ADAM33) 125700082(ADAM19)

NMEL:

110399121(ADAM33) 110405397(ADAM19)

APLA:

101790276(ADAM19) 101795698(ADAM33)

ACYG:

106032686(ADAM19) 106043205(ADAM33)

CATA:

118248337(ADAM33) 118254394(ADAM19)

AFUL:

116488938(ADAM33) 116494786(ADAM19)

TGU:	100225277(ADAM19) 100230755

LSR:	110470823(ADAM19) 110480055

SCAN:

103817497(ADAM19)

PMOA:

120498681(ADAM19) 120509585(ADAM33)

OTC:	121332301(ADAM19) 121348281(ADAM33)

PRUF:

121353461(ADAM33) 121361438(ADAM19)

GFR:	102041146 102042840(ADAM19)

FAB:	101806446(ADAM19) 101821228

OMA:	130252498(ADAM33) 130258749(ADAM19)

PHI:	102099086(ADAM19) 102106770(ADAM33)

PMAJ:

107210795(ADAM19)

CCAE:

111929158(ADAM33) 111935492(ADAM19)

CCW:	104689679(ADAM19) 104697655(ADAM33)

CBRC:

103611538(ADAM19) 103613842(ADAM33)

ETL:	114058342(ADAM19) 114070856

ZAB:	102065888(ADAM19) 102074799(ADAM33)

ACHL:

103799697(ADAM19) 103809587

SVG:	106852957(ADAM19) 106862433

MMEA:

130581353(ADAM19)

HRT:	120759356(ADAM19) 120766105

FPG:	101914790(ADAM19) 101920012

FCH:	102056365(ADAM33) 102058484(ADAM19)

CLV:	102087998(ADAM19) 102089935(ADAM33)

EGZ:	104122571(ADAM19) 104126948(ADAM33)

NNI:	104014262(ADAM19) 104019178(ADAM33)

PCRI:

104027267(ADAM19) 104030479

PLET:

104621761 104624847

EHS:	104510478 104510881(ADAM19)

PCAO:

104046109(ADAM19)

ACUN:

113479147(ADAM33) 113485383(ADAM19)

TALA:

104359100(ADAM33) 104362617(ADAM19)

PADL:

103924930(ADAM19)

AFOR:

103904545(ADAM19) 103908362(ADAM33)

ACHC:

115334152(ADAM19) 115345856(ADAM33)

HALD:

104313829(ADAM19)

HLE:	104839094(ADAM19) 104840112(ADAM33)

AGEN:

126034872 126050938

GCL:	127015557 127022047

CCRI:

104160464 104168162(ADAM19)

CSTI:

104553581(ADAM33)

CMAC:

104486656(ADAM19) 104486726

MUI:	104539297(ADAM19)

BREG:

104629564(ADAM19)

FGA:	104069877(ADAM19) 104074944

GSTE:

104258983(ADAM19)

LDI:	104350699 104353389(ADAM19)

MNB:	103772530(ADAM19)

OHA:	104329730 104336774(ADAM19)

NNT:	104406239 104406626(ADAM19)

SHAB:

115610636(ADAM33) 115615588(ADAM19)

DPUB:

104303975(ADAM19) 104308338

PGUU:

104461646(ADAM19) 104470461

ACAR:

104532230(ADAM19)

CPEA:

104392691(ADAM19) 104398090

AVIT:

104271907(ADAM19) 104276547

CVF:	104284237(ADAM33) 104293882(ADAM19)

CUCA:

104063094(ADAM19) 104063527(ADAM33)

TEO:	104377560 104381607

BRHI:

104492289(ADAM19)

AAM:	106493585(ADAM19) 106497775

AROW:

112964956(ADAM19) 112969417(ADAM33)

NPD:	112954350(ADAM19) 112955531(ADAM33)

TGT:	104575134(ADAM19) 104576584

DNE:	112994349(ADAM19) 112996375(ADAM33)

SCAM:

104148606(ADAM33) 104151110(ADAM19)

ASN:	102374473(ADAM33) 102388630(ADAM19)

AMJ:	102560570(ADAM33) 102573149(ADAM19)

CPOO:

109310211(ADAM19) 109321802(ADAM33)

GGN:	109289755(ADAM19) 109303979(ADAM33)

PSS:	102454440(ADAM19)

CMY:	102935055(ADAM33) 102946400(ADAM19)

CCAY:

125635133(ADAM33) 125641515(ADAM19)

DCC:	119854640(ADAM33) 119860474(ADAM19)

CPIC:

101934049(ADAM33) 101951157(ADAM19)

TST:	117878212(ADAM33) 117881835(ADAM19)

CABI:

116816533 116836684(ADAM19)

MRV:	120370385(ADAM19) 120406886(ADAM33)

ACS:	100554500(adam19) 100555234

PVT:	110077940(ADAM19) 110086601

SUND:

121923300(ADAM19) 121931951(ADAM33)

PBI:	103049402(ADAM19) 103059072

PMUR:

107302949(ADAM19)

CTIG:

120316314 120318151(ADAM19)

TSR:	106543526(ADAM19)

PGUT:

117654736(ADAM19) 117659544

APRI:

131192210(ADAM19) 131203118(ADAM33)

PTEX:

113433845(ADAM19)

NSS:	113421646(ADAM19)

VKO:	123022714(ADAM33) 123034001(ADAM19)

PMUA:

114590863(ADAM19) 114604290(ADAM33)

PRAF:

128408013(ADAM19) 128420628(ADAM33)

ZVI:	118077530 118080463(ADAM19)

HCG:	128328137(ADAM33) 128346130(ADAM19)

GJA:	107121440 107124813(ADAM19)

STOW:

125429738(ADAM19) 125440265(ADAM33)

EMC:	129327610(ADAM19) 129336798(ADAM33)

XLA:	100174810(adam19.S) 373720(adam33.S) 386623(adam33.L)

XTR:	677728(adam33) 677730(adam19)

NPR:	108793189(ADAM19) 108796950

RTEM:

120924637 120932584(ADAM19)

BBUF:

120990538 121007754(ADAM19)

BGAR:

122926522(ADAM19) 122938907

MUO:	115461247 115476622(ADAM19)

GSH:	117351677(ADAM19) 117364557

DRE:	565342(adam19a) 571252(adam19b)

SRX:	107708434 107746536 107751335 107757890

SANH:

107660185 107660716 107661973 107680935

SGH:	107551451 107570237 107587108

CCAR:

109051224 109066859 109093308

CAUA:

113051594 113057665 113078451 113098245 113106601

CGIB:

127962509 127971846 128016627 128027641

PTET:

122349650(adam19a) 122357781(adam19b)

LROH:

127168097(adam19a) 127176267(adam19b)

OMC:	131544025(adam19a) 131553744(adam19b)

PPRM:

120460935(adam19b) 120477909(adam19a)

MAMB:

125259040(adam19b) 125265189(adam19a)

CIDE:

127494085 127515574

MASI:

127412713 127416566 127417593 127441050

TROS:

130560115(adam19a) 130564136(adam19b)

IPU:	108267694(adam19a) 108269365(adam19b)

PHYP:

113529120(adam19) 113540429

SMEO:

124386439(adam19b) 124387340(adam19a)

TFD:	113635175(adam19a) 113636100(adam19b)

AMEX:

103025209 103031173

CMAO:

118806815(adam19b) 118825778(adam19a)

EEE:	113573490 113585299

CHAR:

105893951(adam19a)

TRU:	101073842(adam19)

TFS:	130530981(adam19b)

TNG:	GSTEN00031661G001

LCO:	104924231(adam19) 104927199

NCC:	104946883(adam19)

CGOB:

115014902(adam19) 115023481

ELY:	117246102(adam19a) 117260518(adam19b)

EFO:	125883599(adam19a) 125894631(adam19b)

PLEP:

121947897(adam19b) 121962186

SLUC:

116043378(adam19a) 116064416(adam19b)

ECRA:

117934754(adam19a) 117951507(adam19b)

ESP:	116696634(adam19) 116707249

PFLV:

114546236 114562746

GAT:	120817509(adam19b) 120821229(adam19a)

PPUG:

119210417(adam19b) 119222785(adam19a)

AFB:	129089744(adam19b) 129093331(adam19a)

CLUM:

117737580(adam19b) 117747657(adam19a)

MSAM:

119882206 119889117 119912097(adam19a)

SCHU:

122870519(adam19a) 122880844(adam19b)

CUD:	121504697(adam19a) 121515944(adam19b)

ALAT:

119007354(adam19b) 119027551(adam19a)

MZE:	101485221(adam19) 101486414

ONL:	100707541(adam19) 100711349

OAU:	116311182(adam19a) 116324559(adam19b)

OLA:	101160109 101169545(adam19)

OML:	112153688(adam19b) 112156128(adam19a)

XMA:	102218719 102220219(adam19)

XCO:	114139133(adam19) 114157500

XHE:	116713934(adam19) 116732759

PRET:

103470878(adam19) 103480195

PFOR:

103144551 103148901 103154067

PLAI:

106953484(adam19)

PMEI:

106921761

GAF:	122820414(adam19a) 122837548(adam19b)

CVG:	107086082(adam19) 107101668

CTUL:

119776636(adam19b) 119792634(adam19a)

GMU:	124860551(adam19b) 124880520(adam19a)

NFU:	107396287(adam19)

KMR:	108242304(adam19a) 108245824(adam19b)

ALIM:

106514198 106521915(adam19)

NWH:	119409096(adam19b) 119414538(adam19a)

AOCE:

111575152 111588042(adam19)

MCEP:

125008014(adam19b) 125013183(adam19a)

CSEM:

103385472 103391405(adam19)

POV:	109628884(adam19) 109637674

SSEN:

122766569(adam19a) 122778976(adam19b)

HHIP:

117769368(adam19b) 117779161(adam19a)

HSP:	118102195(adam19a) 118112334(adam19b)

LCF:	108882806(adam19b) 108895187(adam19a)

SDU:	111223613 111226714(adam19)

SLAL:

111664666(adam19) 111667996

XGL:	120784885(adam19b) 120797374(adam19a)

HCQ:	109508312 109529091(adam19)

SSCV:

125983617 125983682

BPEC:

110162345(adam19) 110170716

MALB:

109955552(adam19) 109957182

BSPL:

114864715(adam19b) 114870623(adam19a)

SASA:

106608525 106612150

STRU:

115168177 115198086 115206748

OTW:	112214905(adam19a) 112257012(adam19b)

OMY:	110500901(adam19a) 110504603(adam19b)

OGO:	123992387 124011617 124013773(adam19a)

ONE:	115124285(adam19) 115124902

OKI:	109879192 109879847(adam19) 109896521

SALP:

111967074

SNH:	120034770 120040352 120049556(adam19a)

CCLU:

121532913 121539430 121554317 121571037

ELS:	105020734 105024421(adam19)

SFM:	108930912 108936833(adam19)

PKI:	111853945 111860713(adam19)

AANG:

118223764(adam19b) 118226931 118231732

LOC:	102685923 102696644(adam19)

PSPA:

121294127 121297192 121323963 121329953

ARUT:

117408575 117412871 117421177 117431164

PSEX:

120527918(adam19a) 120542381(adam19b)

LCM:	102350769 102355740(ADAM19)

CMK:	103177301(adam19b)

CPLA:

122556796(adam19b)

LERI:

129701433(adam19b)

CPII:

EPA:

PDAM:

SPIS:

HSY:

Reference

PMID:20849079

Authors

Klein T, Bischoff R

Title

Active metalloproteases of the A Disintegrin and Metalloprotease (ADAM) family: biological function and structure.

Journal

J Proteome Res 10:17-33 (2011)
DOI:10.1021/pr100556z

Reference

PMID:9461614

Authors

Inoue D, Reid M, Lum L, Kratzschmar J, Weskamp G, Myung YM, Baron R, Blobel CP

Title

Cloning and initial characterization of mouse meltrin beta and analysis of the expression of four metalloprotease-disintegrins in bone cells.

Journal

J Biol Chem 273:4180-7 (1998)
DOI:10.1074/jbc.273.7.4180

Sequence

[mmu:11492]

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Ontology (3)   
   KEGG BRITE (3)   
Gene (999)   
   KEGG GENES (582)   
   KEGG MGENES (111)   
   RefGene (303)   
   OC (3)   
Literature (2)   
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