KEGG   ORTHOLOGY: K08675
Entry
K08675                      KO                                     

Name
PRSS15, PIM1
Definition
ATP-dependent Lon protease [EC:3.4.21.53]
Disease
H01824  CODAS syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K08675  PRSS15, PIM1; ATP-dependent Lon protease
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K08675  PRSS15, PIM1; ATP-dependent Lon protease
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.53  endopeptidase La
     K08675  PRSS15, PIM1; ATP-dependent Lon protease
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S16: lon protease family
   K08675  PRSS15, PIM1; ATP-dependent Lon protease
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    K08675  PRSS15, PIM1; ATP-dependent Lon protease
Genes
HSA: 9361(LONP1)
PTR: 455623(LONP1)
PPS: 100976253(LONP1)
PON: 100461951(LONP1)
NLE: 100590941(LONP1)
MCC: 700284(LONP1)
MCF: 101866482(LONP1)
CSAB: 103233746(LONP1)
RRO: 104665476(LONP1)
RBB: 108512096(LONP1)
CJC: 100408135(LONP1)
SBQ: 101042739(LONP1)
MMU: 74142(Lonp1)
MCAL: 110284091(Lonp1)
MPAH: 110335615(Lonp1)
RNO: 170916(Lonp1)
MUN: 110546250(Lonp1)
CGE: 100771385(Lonp1)
NGI: 103737205(Lonp1)
HGL: 101710908(Lonp1)
CCAN: 109688221(Lonp1)
TUP: 102469312(LONP1)
CFA: 611425(LONP1)
VVP: 112935610(LONP1)
AML: 100468447(LONP1)
UMR: 103681856(LONP1)
UAH: 113242858(LONP1)
ORO: 101367221(LONP1)
ELK: 111161696
FCA: 101093417(LONP1)
PPAD: 109255924(LONP1)
AJU: 106975449(LONP1)
BTA: 510796(LONP1)
BOM: 102273928(LONP1)
BIU: 109561716(LONP1)
BBUB: 102413839(LONP1)
CHX: 102182026(LONP1)
OAS: 101109965(LONP1)
SSC: 100511917(LONP1)
CFR: 102505491(LONP1)
CDK: 105091759(LONP1)
BACU: 103008682(LONP1)
LVE: 103076731(LONP1)
OOR: 101275103(LONP1)
DLE: 111165960(LONP1)
PCAD: 102980645(LONP1)
ECB: 100065045(LONP1)
EAI: 106832338(LONP1)
MYB: 102247241(LONP1)
MYD: 102751426(LONP1)
MNA: 107525668(LONP1)
HAI: 109388581(LONP1)
DRO: 112312463(LONP1)
PALE: 102877695(LONP1)
RAY: 107510942(LONP1)
MJV: 108404619(LONP1)
LAV: 100664035(LONP1)
TMU: 101354513
MDO: 100024990(LONP1)
SHR: 100926021(LONP1)
PCW: 110197391(LONP1)
OAA: 100074993(LONP1)
GGA: 768942(LONP1)
MGP: 100538450(LONP1)
CJO: 107325567(LONP1)
NMEL: 110388910(LONP1)
APLA: 101789952(LONP1)
TGU: 100221382
ETL: 114065555(LONP1)
AMJ: 102570078(LONP1)
CMY: 102939356(LONP1)
CPIC: 101938534(LONP1)
PVT: 110072570(LONP1)
PBI: 103066216(LONP1)
PMUA: 114588237(LONP1)
GJA: 107111284(LONP1)
XLA: 108712696(lonp1.L)
XTR: 100492505(lonp1)
NPR: 108789637(LONP1)
DRE: 563257(lonp1)
SRX: 107744642
SGH: 107548847
IPU: 100304917(lonp1)
PHYP: 113543618(lonp1)
AMEX: 103026089(lonp1)
EEE: 113591724(lonp1)
TRU: 101061296(lonp1)
LCO: 104927279(lonp1)
MZE: 101475120(lonp1)
ONL: 100708000(lonp1)
OLA: 101175387(lonp1)
XMA: 102219683(lonp1)
XCO: 114151434(lonp1)
PRET: 103464218(lonp1)
NFU: 107394993(lonp1)
KMR: 108246953(lonp1)
ALIM: 106517295(lonp1)
AOCE: 111564042(lonp1)
CSEM: 103396817(lonp1)
POV: 109625362(lonp1)
LCF: 108900694(lonp1)
SDU: 111240094(lonp1)
SLAL: 111660174(lonp1)
HCQ: 109516958(lonp1)
BPEC: 110162805(lonp1)
MALB: 109972174
SASA: 106560597(lonp1)
OTW: 112251435(lonp1)
SALP: 111975733
ELS: 105031384(lonp1)
SFM: 108921380(lonp1)
PKI: 111847564(lonp1)
LCM: 102359473(LONP1)
CMK: 103188337(lonp1)
RTP: 109915921(lonp1)
BFO: 118410223
CIN: 100178941
SPU: 100889553
SKO: 100369052
DME: Dmel_CG8798(Lon)
DER: 6545346
DSE: 6619377
DSI: Dsimw501_GD12266(Dsim_GD12266)
DAN: 6493589
DSR: 110189879
DWI: 6643034
DNV: 108650987
DHE: 111605069
DVI: 6622872
MDE: 101901482
LCQ: 111677879
AAG: 5568011
AALB: 109399481
AME: 409459
BIM: 100748909
BTER: 100645793
CCAL: 108628100
OBB: 114882760
SOC: 105205478
MPHA: 105833796
AEC: 105147324
ACEP: 105624556
PBAR: 105434097
VEM: 105570504
HST: 105187595
DQU: 106746169
CFO: 105251874
LHU: 105673088
PGC: 109851632
OBO: 105275464
PCF: 106784053
NVI: 100119946
CSOL: 105364819
MDL: 103577847
TCA: 661788
DPA: 109540187
ATD: 109599976
NVL: 108560099
BMOR: 101738203
PRAP: 111003238
TNL: 113493795
API: 100162246
DNX: 107169899
AGS: 114125525
RMD: 113550433
BTAB: 109041197
CLEC: 106665553
ZNE: 110840355
PVM: 113813288
DPTE: 113798312
CEL: CELE_C34B2.6(lonp-1) CELE_Y75B8A.4(lonp-2)
CBR: CBG12802
BMY: Bm1_18860
MYI: 110451944
SHX: MS3_03774
NVE: 5502549
EPA: 110243112
PDAM: 113682626
SPIS: 111342707
DGT: 114533888
ATH: AT3G05780(LON3) AT3G05790(LON4) AT5G26860(LON1)
ALY: 9308311
THJ: 104820100
CPAP: 110815328
CIT: 102620332
TCC: 18600571
EGR: 104428250
VRA: 106772262
VAR: 108325921
VUN: 114191692
CCAJ: 109819213
CAM: 101510578
LJA: Lj0g3v0183909.1(Lj0g3v0183909.1)
ADU: 107465214
AIP: 107618105
FVE: 101313904
RCN: 112192813
PPER: 18774588
PMUM: 103344549
PAVI: 110762891
MDM: 103450854
PXB: 103962312
ZJU: 107407834
CSV: 101204375
MCHA: 111023269
CMAX: 111465425
CMOS: 111444355
CPEP: 111798716
JCU: 105647420
HBR: 110641817
MESC: 110621016
POP: 7478901
PEU: 105125157
JRE: 108981232
VVI: 100254508
SLY: 101264562
SPEN: 107002475
SOT: 102590267
CANN: 107845715
NTA: 107796400
NSY: 104228685
NTO: 104120154
NAU: 109233012
SIND: 105176824
OEU: 111390212
HAN: 110918283
LSV: 111878015
CCAV: 112516489
DCR: 108209611
BVG: 104890770
SOE: 110796705
PSOM: 113297859
BDI: 100844749
ATS: 109738385(LOC109738385)
SBI: 8077511
ZMA: 103647953 732810(LON2)
SITA: 101775616
PDA: 103723402
EGU: 105039934
MUS: 103990534
DCT: 110099479
PEQ: 110036410
AOF: 109842711
ATR: 18430231
PPP: 112290438
APRO: F751_5552
SCE: YBL022C(PIM1)
ERC: Ecym_6190
KMX: KLMA_20035(PIM1)
NCS: NCAS_0B05620(NCAS0B05620)
NDI: NDAI_0B02960(NDAI0B02960)
TPF: TPHA_0H00180(TPHA0H00180)
TBL: TBLA_0A08760(TBLA0A08760)
TDL: TDEL_0B04430(TDEL0B04430)
KAF: KAFR_0C02780(KAFR0C02780)
CAL: CAALFM_CR04340WA(PIM1)
SLB: AWJ20_2088(PIM1)
NCR: NCU05261
NTE: NEUTE1DRAFT61761(NEUTE1DRAFT_61761)
MGR: MGG_11141
SSCK: SPSK_02974
MAW: MAC_01341
MAJ: MAA_06367
CMT: CCM_02548
BFU: BCIN_07g06160(Bcpim1)
MBE: MBM_01738
ANI: AN6193.2
ANG: ANI_1_516024(An02g03760)
ABE: ARB_01104
TVE: TRV_04140
PTE: PTT_07258
SPO: SPAC22F3.06c(lon1)
CNE: CND03865
CNB: CNBD2440
TASA: A1Q1_01255
ABP: AGABI1DRAFT75578(AGABI1DRAFT_75578)
ABV: AGABI2DRAFT202009(AGABI2DRAFT_202009)
MGL: MGL_4002
MRT: MRET_4237
TAN: TA12745
TPV: TP02_0361
BBO: BBOV_III006020(17.m07531)
AHEL: Q31a_24800(lon_1)
 » show all
Reference
  Authors
Bota DA, Davies KJ
  Title
Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism.
  Journal
Nat Cell Biol 4:674-80 (2002)
DOI:10.1038/ncb836
Reference
  Authors
Lu B, Yadav S, Shah PG, Liu T, Tian B, Pukszta S, Villaluna N, Kutejova E, Newlon CS, Santos JH, Suzuki CK
  Title
Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance.
  Journal
J Biol Chem 282:17363-74 (2007)
DOI:10.1074/jbc.M611540200
  Sequence
[hsa:9361]

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