KEGG   ORTHOLOGY: K08784Help
Entry
K08784                      KO                                     

Name
HTRA1, PRSS11
Definition
HtrA serine peptidase 1 [EC:3.4.21.-]
Disease
H00821  Age-related macular degeneration
H01757  Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases
    K08784  HTRA1, PRSS11; HtrA serine peptidase 1
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts
    K08784  HTRA1, PRSS11; HtrA serine peptidase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.-  
     K08784  HTRA1, PRSS11; HtrA serine peptidase 1
Peptidases [BR:ko01002]
 Serine Peptidases
  Family S1: chymotrypsin family
   K08784  HTRA1, PRSS11; HtrA serine peptidase 1
Chaperones and folding catalysts [BR:ko03110]
 Other chaperones and cochaperones
  DegP / HtrA
   K08784  HTRA1, PRSS11; HtrA serine peptidase 1
BRITE hierarchy
Genes
HSA: 5654(HTRA1)
PTR: 450792(HTRA1)
PPS: 100984844(HTRA1)
GGO: 101127178(HTRA1)
PON: 100437050(HTRA1)
NLE: 100583976(HTRA1)
MCC: 705855(HTRA1)
MCF: 102126844(HTRA1)
CSAB: 103216638(HTRA1)
RRO: 104658066(HTRA1)
RBB: 108529745(HTRA1)
CJC: 100398769(HTRA1)
SBQ: 101030381(HTRA1)
MMU: 56213(Htra1)
RNO: 65164(Htra1)
CGE: 100762962(Htra1)
NGI: 103729266(Htra1)
HGL: 101703079(Htra1)
CCAN: 109691638(Htra1)
OCU: 100008705(HTRA1)
TUP: 102497616(HTRA1)
CFA: 477852(HTRA1)
AML: 100468862(HTRA1)
UMR: 103659391(HTRA1)
ORO: 101377025(HTRA1)
FCA: 101095920(HTRA1)
PTG: 102949412(HTRA1)
AJU: 106969384(HTRA1)
BTA: 282326(HTRA1)
BOM: 102269881(HTRA1)
BIU: 109553084(HTRA1)
PHD: 102336406(HTRA1)
CHX: 102174540(HTRA1)
OAS: 101101854(HTRA1)
SSC: 100515628(HTRA1)
CFR: 102510440(HTRA1)
CDK: 105104228(HTRA1)
BACU: 103007240(HTRA1)
LVE: 103087438(HTRA1)
OOR: 101269446(HTRA1)
ECB: 100064570(HTRA1)
EPZ: 103542384(HTRA1)
EAI: 106824430(HTRA1)
MYB: 102252542(HTRA1)
MYD: 102764423(HTRA1)
HAI: 109382985(HTRA1)
RSS: 109458911(HTRA1)
PALE: 102883658(HTRA1)
LAV: 100675235(HTRA1)
TMU: 101352358
MDO: 100025560(HTRA1)
SHR: 100930647(HTRA1)
OAA: 100093346
GGA: 100857572(HTRA1)
MGP: 100541363(HTRA1)
CJO: 107316299(HTRA1)
APLA: 101793219(HTRA1)
ACYG: 106038992(HTRA1)
TGU: 100219623(HTRA1)
SCAN: 103814108(HTRA1)
GFR: 102043139(HTRA1)
FAB: 101813424(HTRA1)
PHI: 102106039(HTRA1)
PMAJ: 107206893(HTRA1)
CCAE: 111931380(HTRA1)
CCW: 104694592(HTRA1)
FPG: 101920321(HTRA1)
FCH: 102058838(HTRA1)
CLV: 102096252(HTRA1)
EGZ: 104123677(HTRA1)
NNI: 104020575(HTRA1)
ACUN: 113481713(HTRA1)
AAM: 106499018(HTRA1)
ASN: 102385435(HTRA1)
AMJ: 102568843(HTRA1)
PSS: 102448440(HTRA1)
CMY: 102941421(HTRA1)
CPIC: 101942959(HTRA1)
ACS: 100559415(htra4) 100564246(htra1)
PVT: 110072161(HTRA4) 110075336(HTRA1)
PBI: 103055911 103064390(HTRA1)
PMUR: 107288605(HTRA1)
GJA: 107122324(HTRA1)
XLA: 108696094(htra1.L) 108711647(htra4.L) 108712278 496061(htra1.S)
XTR: 100488607(htra4) 780187(htra1)
DRE: 100334257(htra4) 431766(htra1a) 565082(htra1b)
IPU: 108255963(htra4) 108270147 108273788(htra1)
TRU: 101062667(htra1) 101076407
NCC: 104944757 104946544(htra1)
OLA: 101160199(htra1) 105355810
XMA: 102218195 102219577(htra1)
PRET: 103476703 103481869(htra1)
NFU: 107375930 107387249(htra1)
CSEM: 103382293 103387077(htra1)
SFM: 108932767 108939508(htra1) 108940300(htra4)
LCM: 102345424(HTRA1) 102361645(HTRA4)
CIN: 100182899
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Campioni M, Severino A, Manente L, Tuduce IL, Toldo S, Caraglia M, Crispi S, Ehrmann M, He X, Maguire J, De Falco M, De Luca A, Shridhar V, Baldi A
  Title
The serine protease HtrA1 specifically interacts and degrades the tuberous sclerosis complex 2 protein.
  Journal
Mol Cancer Res 8:1248-60 (2010)
DOI:10.1158/1541-7786.MCR-09-0473

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