KEGG   ORTHOLOGY: K08798Help
Entry
K08798                      KO                                     

Name
MARK
Definition
MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K08798  MARK; MAP/microtubule affinity-regulating kinase
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K08798  MARK; MAP/microtubule affinity-regulating kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K08798  MARK; MAP/microtubule affinity-regulating kinase
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   K08798  MARK; MAP/microtubule affinity-regulating kinase
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Others
     K08798  MARK; MAP/microtubule affinity-regulating kinase
BRITE hierarchy
Genes
HSA: 2011(MARK2) 4139(MARK1) 4140(MARK3) 57787(MARK4)
PTR: 453184(MARK3) 456123(MARK4) 469683(MARK1) 741494(MARK2)
PPS: 100977729(MARK3) 100980135(MARK2) 100989285(MARK1) 100992653(MARK4)
GGO: 101127838(MARK3) 101133345(MARK1) 101136507(MARK4) 101142194(MARK2) 109028475
PON: 100431691(MARK3) 100433440(MARK2) 100454879(MARK4) 100456064(MARK1)
NLE: 100579541(MARK3) 100581822(MARK1) 100594774(MARK4) 100595666(MARK2)
MCC: 695234(MARK3) 710695(MARK1) 715346(MARK4) 718065(MARK2)
MCF: 101925189(MARK3) 102134233(MARK1) 102143161(MARK2) 102145145(MARK4)
CSAB: 103229759(MARK3) 103230059(MARK1) 103233568(MARK2) 103235517(MARK4) 103247299
RRO: 104654423(MARK3) 104666094(MARK1) 104672880(MARK2) 104673449(MARK4)
RBB: 108514973(MARK3) 108528271(MARK1) 108531043(MARK4) 108536144(MARK2)
SBQ: 101040271(MARK3) 101041655(MARK1) 101043162(MARK2) 101046069(MARK4) 104651241
MMU: 13728(Mark2) 17169(Mark3) 226778(Mark1) 232944(Mark4)
RNO: 117016(Mark1) 170577(Mark3) 60328(Mark2) 680407(Mark4)
HGL: 101707850(Mark2) 101711152(Mark1) 101713017(Mark3) 101719511 101726420(Mark4)
TUP: 102472413 102479788(MARK3) 102485504 102487677(MARK2) 102493458(MARK4) 102495741(MARK1)
CFA: 478965(MARK1) 483769(MARK2) 484449(MARK4) 611285(MARK3)
AML: 100467224(MARK2) 100474641(MARK1) 100481440(MARK4) 100482675(MARK3)
UMR: 103657182(MARK4) 103658278(MARK1) 103676892(MARK3) 103679415(MARK2)
ORO: 101364565(MARK1) 101376779(MARK3) 101381557(MARK4) 101381999(MARK2)
FCA: 101084500(MARK4) 101085385(MARK3) 101089681 101095375(MARK2) 101099270(MARK1) 105260366
PTG: 102949758(MARK3) 102954510(MARK1) 102960665(MARK2) 102971274(MARK4)
AJU: 106973600(MARK4) 106975979(MARK3) 106979489(MARK1) 106981743(MARK2)
BTA: 525675(MARK4) 534872(MARK3) 535197(MARK2) 539563(MARK1)
BOM: 102271460(MARK3) 102274607(MARK1) 102280394(MARK2) 102287824(MARK4)
BIU: 109554417(MARK2) 109569923(MARK1) 109571758(MARK4) 109575252 109575462(MARK3)
PHD: 102318162(MARK4) 102320726(MARK1) 102324872(MARK2) 102326255(MARK3) 102328303
OAS: 101105030(MARK3) 101105515(MARK1) 101115819(MARK4) 101121302 106991822
SSC: 100624209(MARK4) 100624523(MARK1) 100625932(MARK3) 100737238(MARK2)
CFR: 102503683(MARK1) 102504704(MARK4) 102513459(MARK3) 102520242(MARK2)
CDK: 105095458(MARK4) 105100037(MARK1) 105101529(MARK2) 105103448(MARK3)
BACU: 103000038(MARK4) 103000346 103000817(MARK3) 103011805(MARK2) 103015107 103020185(MARK1)
LVE: 103075860(MARK1) 103076919(MARK4) 103082212(MARK3) 103088748(MARK2)
OOR: 101274025(MARK1) 101288141(MARK4) 101289994(MARK3) 101290100(MARK2)
ECB: 100049882(MARK2) 100054005(MARK1) 100059464(MARK3) 100070770(MARK4)
EPZ: 103550608 103559459(MARK1) 103563413(MARK3) 103565276(MARK2) 103567009(MARK4)
EAI: 106829538(MARK1) 106833646(MARK2) 106839620(MARK3) 106848424(MARK4)
MYD: 102752116(MARK2) 102757894(MARK4) 102765288 102769219(MARK3) 102772379(MARK1)
RSS: 109438189(MARK2) 109452540(MARK1) 109455574(MARK3) 109459618 109459933(MARK4)
PALE: 102882803(MARK2) 102886835(MARK1) 102887051(MARK3) 102887913(MARK4)
LAV: 100654685(MARK3) 100655111(MARK1) 100666114(MARK2) 100672785(MARK4)
MDO: 100014334(MARK2) 100021111(MARK3) 100024528(MARK1) 100031216(MARK4)
SHR: 100914670(MARK2) 100917510(MARK1) 100923427(MARK4) 100925650(MARK3)
OAA: 100076749(MARK3) 100080890(MARK1)
GGA: 107049628(MARK2) 421342(MARK1) 423480(MARK3)
MGP: 100544800(MARK1) 100550645(MARK3)
CJO: 107307831 107311024(MARK1) 107315298(MARK3)
APLA: 101792584 101793421(MARK1) 101793738(MARK3)
ACYG: 106031560(MARK1) 106047003(MARK3)
TGU: 100219055(MARK3) 100224882(MARK1)
GFR: 102037185(MARK1) 102037764(MARK3) 102039455
FAB: 101805653(MARK1) 101805833(MARK2) 101807077(MARK3)
PHI: 102103467(MARK2) 102103520(MARK4) 102108680(MARK3) 102113253(MARK1)
PMAJ: 107202146(MARK1) 107205735(MARK3)
CCAE: 111926228(MARK1) 111929781(MARK3)
CCW: 104685620(MARK1) 104686768(MARK3)
FPG: 101917002(MARK1) 101919390(MARK3) 101920950(MARK4)
FCH: 102047447(MARK1) 102058488(MARK3) 106631056(MARK4)
CLV: 102083918(MARK3) 102085964(MARK1) 102096404
EGZ: 104124724(MARK3) 104124786(MARK1) 104128871
AAM: 106482980(MARK3) 106490422(MARK1) 106492209(MARK4)
ASN: 102371105(MARK3) 102375333(MARK2) 102379467(MARK4) 102380403(MARK1)
AMJ: 102558221(MARK3) 102569198(MARK1) 102572476(MARK4) 102576315(MARK2) 106739493
PSS: 102454865(MARK1) 102456409(MARK3) 102458022 102461077(MARK2)
CMY: 102930948(MARK1) 102936538(MARK2) 102942529(MARK3) 102944699(MARK4)
CPIC: 101942587(MARK1) 101948522(MARK2) 101950782(MARK4) 101953187(MARK3)
ACS: 100553482(mark4) 100556651(mark3) 100559635(mark1) 100566972(mark2) 103282645
PVT: 110075360(MARK1) 110075636(MARK4) 110084978(MARK2) 110087348(MARK3)
PBI: 103055239 103059538(MARK2) 103062879(MARK1) 103067320(MARK4) 103068272(MARK3)
GJA: 107114938(MARK4) 107115989(MARK3) 107118254(MARK2) 107122322(MARK1)
XLA: 108698519(mark4.L) 108700199(mark4.S) 108716465 380117(mark2) 398441(mark2.S) 399395(mark3.L) 432201(mark1.S) 495312
XTR: 100329119(mark3) 100490022(mark1) 100491038(mark4) 594939(mark2)
NPR: 108794317(MARK2) 108798730(MARK3) 108800084(MARK1) 108803552
DRE: 100003170(mark1) 100005996(mark2b) 334300(mark3a) 562231(mark2a) 571279(si:dkey-31m14.7) 767634(mark3b)
IPU: 108258043(MARK3) 108260538 108263198(mark3) 108267665(mark2) 108271264(MARK1) 108277475(mark4) 108278749
TRU: 101061627(mark3) 101067343 101071085(mark2) 101074476(mark1) 101076656(mark4)
PRET: 103457135 103458144(mark3) 103475165(mark4) 103476195 103476859(mark1) 103480763(mark2)
KMR: 108231002(mark3) 108242549 108242880(mark2) 108244449(mark1) 108247889(mark4) 108249838
CSEM: 103377897(mark4) 103382930(mark3) 103384239(mark2) 103387207(mark1) 103394987
BPEC: 110153433(mark3) 110156240(mark2) 110159138(mark1) 110169011 110172687
LCM: 102345624(MARK2) 102353519(MARK4) 102355219(MARK1) 102365343(MARK3)
CIN: 100184744
SPU: 592325(MARK3)
APLC: 110975225
DME: Dmel_CG17216(KP78b) Dmel_CG6715(KP78a)
DPE: 6590845
DSI: Dsimw501_GD20664(Dsim_GD20664) Dsimw501_GD20665(Dsim_GD20665)
AAG: 5579800
AME: 410717
BIM: 100741266
BTER: 100645231
SOC: 105199532
ACEP: 105618776
PBAR: 105430832
HST: 105183960
PCF: 106786758
NVI: 100122482
MDL: 103572676
TCA: 656926(par-1) 661848
NVL: 108557992
API: 100166936
DNX: 107166309
CLEC: 106666962
ZNE: 110833491
FCD: 110859347
TUT: 107369271
CEL: CELE_H39E23.1(par-1)
CBR: CBG04756(Cbr-par-1)
BMY: Bm1_29690
TSP: Tsp_02539
CRG: 105333342
LAK: 106171909
EPA: 110235688
ADF: 107334738
HMG: 100214508(mark3)
SSCK: SPSK_06010
DDI: DDB_G0281895(mrkC) DDB_G0292304(mrkA)
DFA: DFA_05190(mrkB) DFA_07946(mrkC)
SMIN: v1.2.027508.t1(symbB.v1.2.027508.t1)
SPAR: SPRG_10397
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Dequiedt F, Martin M, Von Blume J, Vertommen D, Lecomte E, Mari N, Heinen MF, Bachmann M, Twizere JC, Huang MC, Rider MH, Piwnica-Worms H, Seufferlein T, Kettmann R
  Title
New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases.
  Journal
Mol Cell Biol 26:7086-102 (2006)
DOI:10.1128/MCB.00231-06
  Sequence
[hsa:4140 2011]
Reference
  Authors
Biernat J, Wu YZ, Timm T, Zheng-Fischhofer Q, Mandelkow E, Meijer L, Mandelkow EM
  Title
Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity.
  Journal
Mol Biol Cell 13:4013-28 (2002)
DOI:10.1091/mbc.02-03-0046
  Sequence
[hsa:2011]

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