KEGG   ORTHOLOGY: K09222Help
Entry
K09222                      KO                                     

Name
REST
Definition
RE1-silencing transcription factor
Pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K09222  REST; RE1-silencing transcription factor
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    K09222  REST; RE1-silencing transcription factor
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09222  REST; RE1-silencing transcription factor
Transcription factors [BR:ko03000]
 Eukaryotic type
  Zinc finger
   Cys2His2 developmental/cell cycle regulators, Krueppel-like
    K09222  REST; RE1-silencing transcription factor
BRITE hierarchy
Genes
HSA: 5978(REST)
PTR: 471235(REST)
PPS: 100968041(REST)
GGO: 101143077(REST)
PON: 100449247(REST)
NLE: 100583285(REST)
MCC: 100425257(REST)
MCF: 102116020(REST)
CSAB: 103235636(REST)
RRO: 104682704(REST)
RBB: 108513477(REST)
CJC: 100399762(REST)
SBQ: 101031593(REST)
MMU: 19712(Rest)
MCAL: 110294391(Rest)
MPAH: 110330594(Rest)
RNO: 83618(Rest)
MUN: 110560331(Rest)
CGE: 100756480(Rest)
NGI: 103734374(Rest)
HGL: 101718905(Rest)
CCAN: 109691663(Rest)
OCU: 100341801(REST)
TUP: 102488680(REST)
CFA: 482163(REST)
VVP: 112923703(REST)
AML: 100483588(REST)
UMR: 103672754(REST)
UAH: 113262528(REST)
ORO: 101384761(REST)
FCA: 101086719(REST)
PTG: 102949845(REST)
PPAD: 109278581(REST)
AJU: 106971663(REST)
BTA: 507148(REST) 615792
BBUB: 102396779(REST) 102398050
CHX: 102180114 102181107(REST)
SSC: 100520754(REST) 100621006
CDK: 105091557(REST) 105102812
LVE: 103078260(REST) 103090669
ECB: 100058152(REST)
EPZ: 103556481(REST)
EAI: 106841687(REST)
MYB: 102261820(REST)
MYD: 102755535(REST)
MNA: 107533240(REST)
HAI: 109394382(REST)
DRO: 112322213(REST)
PALE: 102879115(REST)
RAY: 107517714(REST)
MJV: 108387770(REST)
LAV: 100659269(REST)
TMU: 101345477
MDO: 100016000(REST)
SHR: 100921808(REST)
PCW: 110200152(REST)
OAA: 100078457(REST)
GGA: 422623(REST)
MGP: 100549206(REST)
CJO: 107313403(REST)
NMEL: 110399054(REST)
APLA: 101791754(REST)
ACYG: 106046092(REST)
TGU: 100228357(REST)
LSR: 110471704(REST)
SCAN: 103825985(REST)
GFR: 102031873(REST)
FAB: 101814797(REST)
PHI: 102099605(REST)
PMAJ: 107203260(REST)
CCAE: 111927808(REST)
CCW: 104697147(REST)
ETL: 114065781(REST)
FPG: 101911619(REST)
FCH: 102054905(REST)
CLV: 102087713(REST)
EGZ: 104122668(REST)
NNI: 104021209(REST)
ACUN: 113479642(REST)
PADL: 103921756(REST)
AAM: 106495841(REST)
ASN: 102378229(REST)
AMJ: 102565143(REST)
PSS: 102445246(REST)
CMY: 102941140
CPIC: 101947249(REST)
ACS: 100564403(rest)
PVT: 110091002(REST)
PBI: 103055825(REST)
TSR: 106550815(REST)
PMUA: 114587605(REST)
GJA: 107106832(REST)
XLA: 373614(rest.S) 734238(rest.L)
XTR: 734016(rest)
DRE: 564772(rest)
SRX: 107750328 107751319(rest)
SGH: 107562372(rest) 107587061
IPU: 108275113(rest)
PHYP: 113539864(rest)
AMEX: 103034010(rest)
EEE: 113587934(rest)
TRU: 100216471(rest) 115246415
LCO: 104936076(rest)
NCC: 104968113(rest)
MZE: 101472807(rest)
ONL: 100693239(rest)
OLA: 101171397(rest)
XMA: 102216701(rest)
XCO: 114139602(rest)
PRET: 103471787(rest)
CVG: 107082720(rest)
NFU: 107381113(rest)
KMR: 108228877(rest)
ALIM: 106534158(rest)
AOCE: 111570938(rest)
CSEM: 103390793(rest)
POV: 109645180
LCF: 108885295(rest)
SDU: 111233497(rest)
SLAL: 111665592
HCQ: 109508297(rest)
BPEC: 110168020(rest)
MALB: 109951107(rest)
ELS: 105007536(rest)
SFM: 108938792(rest)
PKI: 111848741(rest)
LCM: 102347070 102365460(REST)
CMK: 103182119(rest)
RTP: 109913183
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7697725
  Authors
Chong JA, Tapia-Ramirez J, Kim S, Toledo-Aral JJ, Zheng Y, Boutros MC, Altshuller YM, Frohman MA, Kraner SD, Mandel G
  Title
REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons.
  Journal
Cell 80:949-57 (1995)
DOI:10.1016/0092-8674(95)90298-8
  Sequence
[hsa:5978]
Reference
PMID:8568247
  Authors
Scholl T, Stevens MB, Mahanta S, Strominger JL
  Title
A zinc finger protein that represses transcription of the human MHC class II gene, DPA.
  Journal
J Immunol 156:1448-57 (1996)
  Sequence
[hsa:5978]

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