KEGG   ORTHOLOGY: K09234Help
Entry
K09234                      KO                                     

Name
WT1
Definition
Wilms tumor protein 1
Pathway
ko05202  Transcriptional misregulation in cancer
Disease
H00607  46,XY gonadal dysgenesis
H01657  Nephrotic syndrome
H01985  Desmoplastic small round cell tumor
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09161 Cancers: Overview
   05202 Transcriptional misregulation in cancer
    K09234  WT1; Wilms tumor protein 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09234  WT1; Wilms tumor protein 1
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Zinc finger
   Cys2His2 developmental/cell cycle regulators, GLI-like
    K09234  WT1; Wilms tumor protein 1
BRITE hierarchy
Genes
HSA: 7490(WT1)
PTR: 737987(WT1)
PPS: 100974201(WT1)
GGO: 101151613(WT1)
PON: 100437305(WT1)
NLE: 100603690(WT1)
MCC: 696061(WT1)
MCF: 102131274(WT1)
CSAB: 103238102(WT1)
RRO: 104658375(WT1)
RBB: 108513839(WT1)
CJC: 100399350(WT1)
SBQ: 101027475(WT1)
MMU: 22431(Wt1)
RNO: 24883(Wt1)
CGE: 100767732(Wt1)
NGI: 103748712(Wt1)
HGL: 101714640(Wt1)
CCAN: 109676429(Wt1)
OCU: 100346776(WT1)
TUP: 102488718(WT1)
CFA: 609253(WT1)
AML: 100479572(WT1)
UMR: 103659346(WT1)
ORO: 101380701(WT1)
FCA: 101088518(WT1)
PTG: 102968959(WT1)
AJU: 106970264(WT1)
BTA: 782183(WT1)
BOM: 102275862(WT1)
BIU: 109569932(WT1)
PHD: 102344747(WT1)
CHX: 102180242(WT1)
OAS: 100101227(WT1)
SSC: 397338(WT1)
CFR: 102507153(WT1)
CDK: 105106916(WT1)
BACU: 103011643(WT1)
LVE: 103069849(WT1)
OOR: 101288273(WT1)
ECB: 100072704(WT1)
EPZ: 103554490(WT1)
EAI: 106845261(WT1)
MYB: 102248003(WT1)
MYD: 102765339(WT1)
HAI: 109381159(WT1)
RSS: 109450794(WT1)
PALE: 102878723(WT1)
LAV: 100675763(WT1)
TMU: 101356687
MDO: 100031140(WT1)
SHR: 100917886(WT1)
OAA: 100075190(WT1)
GGA: 101747322(WT1)
MGP: 100545785(WT1)
CJO: 107314356(WT1)
APLA: 101799253(WT1)
ACYG: 106033899(WT1)
TGU: 100222371(WT1)
SCAN: 103822096(WT1)
GFR: 102040840(WT1)
FAB: 101809124(WT1)
PHI: 102101293(WT1)
PMAJ: 107206258(WT1)
CCAE: 111930454(WT1)
CCW: 104693002(WT1)
FPG: 101922515(WT1)
FCH: 102051128(WT1)
CLV: 102086762(WT1)
EGZ: 104133518(WT1)
NNI: 104009509(WT1)
ACUN: 113481234(WT1)
ASN: 102381580(WT1)
AMJ: 102563352(WT1)
PSS: 102461242(WT1)
CMY: 102937751(WT1)
CPIC: 101950000(WT1)
ACS: 100556165(wt1)
PVT: 110080052(WT1)
PBI: 103066534(WT1)
GJA: 107109060(WT1)
XLA: 373588(wt1.S) 378664(wt1.L)
XTR: 100216184(wt1)
NPR: 108796326(WT1)
DRE: 30245(wt1a)
IPU: 108264570 108268387(wt1)
PHYP: 113526949 113546516(wt1)
AMEX: 103045853(wt1)
TRU: 101068345 101074610(wt1)
LCO: 104927739(wt1) 104938374
MZE: 101472020 101482946(wt1)
OLA: 100049268(wt1) 100125521(wt1)
XMA: 102219497(wt1) 102235611
KMR: 108246890 108250745(wt1)
CSEM: 103379141(wt1) 103379534
LCF: 108877831(wt1) 108902295
SDU: 111218254(wt1) 111222481
HCQ: 109520029 109531578(wt1)
BPEC: 110169439 110175506(wt1)
SASA: 100380493(wt1) 106573231(wt1) 106587831
SFM: 108941307(wt1)
LCM: 102355188(WT1)
CMK: 103175043(wt1)
AQU: 100637386
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Weiss TC, Romaniuk PJ
  Title
Contribution of individual amino acids to the RNA binding activity of the Wilms' tumor suppressor protein WT1.
  Journal
Biochemistry 48:148-55 (2009)
DOI:10.1021/bi801586a
  Sequence
[hsa:7490]
Reference
  Authors
Rivera MN, Kim WJ, Wells J, Stone A, Burger A, Coffman EJ, Zhang J, Haber DA
  Title
The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity.
  Journal
Proc Natl Acad Sci U S A 106:8338-43 (2009)
DOI:10.1073/pnas.0811349106
  Sequence
[hsa:7490]

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