KEGG   ORTHOLOGY: K09438
Entry
K09438                      KO                                     

Name
SPI1
Definition
transcription factor PU.1
Pathway
ko04380  Osteoclast differentiation
ko05166  Human T-cell leukemia virus 1 infection
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05221  Acute myeloid leukemia
Disease
H00003  Acute myeloid leukemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K09438  SPI1; transcription factor PU.1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K09438  SPI1; transcription factor PU.1
   05202 Transcriptional misregulation in cancer
    K09438  SPI1; transcription factor PU.1
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    K09438  SPI1; transcription factor PU.1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K09438  SPI1; transcription factor PU.1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09438  SPI1; transcription factor PU.1
Transcription factors [BR:ko03000]
 Eukaryotic type
  Helix-turn-helix
   Tryptophan clusters Ets-type
    K09438  SPI1; transcription factor PU.1
Genes
HSA: 6688(SPI1)
PTR: 451169(SPI1)
PPS: 100969631(SPI1)
GGO: 101131042(SPI1)
PON: 100449540(SPI1)
NLE: 100580017(SPI1)
MCC: 712010(SPI1)
MCF: 102140931(SPI1)
CSAB: 103236117(SPI1)
RRO: 104668411(SPI1)
RBB: 108516316(SPI1)
CJC: 100391618(SPI1)
SBQ: 101028746(SPI1)
MMU: 20375(Spi1)
MCAL: 110289690(Spi1)
MPAH: 110318694(Spi1)
RNO: 366126(Spi1)
MUN: 110550731(Spi1)
CGE: 100763362(Spi1)
NGI: 103742512(Spi1)
HGL: 101707724(Spi1)
CCAN: 109696198(Spi1)
OCU: 103351779(SPI1)
TUP: 102475013(SPI1)
CFA: 611255(SPI1)
VVP: 112924068(SPI1)
AML: 100476314(SPI1)
UMR: 103672387(SPI1)
UAH: 113264961(SPI1)
ORO: 101375564(SPI1)
ELK: 111149957
FCA: 101094951(SPI1)
PTG: 102951664(SPI1)
PPAD: 109245121(SPI1)
AJU: 106978062(SPI1)
BTA: 507100(SPI1)
BOM: 102276379(SPI1)
BIU: 109569922(SPI1)
BBUB: 102398044(SPI1)
CHX: 102186416(SPI1)
OAS: 101119756(SPI1)
SSC: 414912(SPI1)
CFR: 102512798(SPI1)
CDK: 105106877(SPI1)
BACU: 102998620(SPI1)
LVE: 103075166(SPI1)
OOR: 101273237(SPI1)
PCAD: 102994533(SPI1)
ECB: 100051397(SPI1)
EPZ: 103561118(SPI1)
EAI: 106844013(SPI1)
MYB: 102246027(SPI1)
MYD: 102756793(SPI1)
MNA: 107530287(SPI1)
HAI: 109390241(SPI1)
DRO: 112303386(SPI1)
PALE: 102880490(SPI1)
RAY: 107511843(SPI1)
MJV: 108383733(SPI1)
LAV: 100673678(SPI1)
TMU: 101352574
MDO: 100016353(SPI1)
SHR: 100932651(SPI1)
PCW: 110223926(SPI1)
OAA: 100076432(SPI1)
GGA: 395879(SPI1)
CJO: 107314837(SPI1)
NMEL: 110401564(SPI1)
APLA: 101804780(SPI1)
ACYG: 106043819(SPI1)
TGU: 100230501(SPI1)
LSR: 110472056(SPI1)
SCAN: 103826697(SPI1)
GFR: 102036864(SPI1)
FAB: 101816372(SPI1)
PHI: 102111706(SPI1)
PMAJ: 107206455(SPI1)
CCAE: 111930166(SPI1)
CCW: 104697845(SPI1)
ETL: 114058647(SPI1)
FPG: 101910291(SPI1)
FCH: 102048829(SPI1)
CLV: 102086101(SPI1)
EGZ: 104134068(SPI1)
NNI: 104020387(SPI1)
ACUN: 113480607(SPI1)
PADL: 103921701(SPI1)
AAM: 106498161(SPI1)
ASN: 102371508(SPI1)
AMJ: 106736783(SPI1)
PSS: 102454428(SPI1)
CMY: 102938883(SPI1)
CPIC: 101947317(SPI1)
ACS: 100551710(spi1)
PVT: 110082157(SPI1)
PBI: 103067729(SPI1)
PMUR: 107289839(SPI1)
TSR: 106545038(SPI1)
PMUA: 114583928(SPI1)
GJA: 107123207(SPI1)
XTR: 100125218(spi1)
NPR: 108791608(SPI1)
DRE: 30117(spi1b) 751704(spi1a)
IPU: 100528991(spi1) 108275191
PHYP: 113529826 113540977(spi1)
AMEX: 103033056(spi1) 103040324
EEE: 113573140 113582094(spi1)
TRU: 101067174(spi1) 101075459
LCO: 104919252(spi1) 104932830
MZE: 101469934 101483532(spi1)
ONL: 100690463(spi1) 100692791
XMA: 102237201(spi1) 111608472
CVG: 107090602(spi1) 107096874
ALIM: 106521153 106530489(spi1)
POV: 109624156 109624882(spi1)
SLAL: 111667040 111668291(spi1)
BPEC: 110169631 110172873(spi1)
SASA: 106561799 106563523(SPI1) 106584705(SPI1) 106587480(SPI1) 106592577(SPI1)
ELS: 105018184 105022246(spi1)
LCM: 102348097(SPI1)
CMK: 103173055(SpiD) 103173579
RTP: 109935573
 » show all
Reference
  Authors
Burda P, Laslo P, Stopka T
  Title
The role of PU.1 and GATA-1 transcription factors during normal and leukemogenic hematopoiesis.
  Journal
Leukemia 24:1249-57 (2010)
DOI:10.1038/leu.2010.104
Reference
PMID:1693183
  Authors
Ray D, Culine S, Tavitain A, Moreau-Gachelin F
  Title
The human homologue of the putative proto-oncogene Spi-1: characterization and expression in tumors.
  Journal
Oncogene 5:663-8 (1990)
  Sequence
[hsa:6688]

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