KEGG   ORTHOLOGY: K09591Help
Entry
K09591                      KO                                     

Name
DET2
Definition
steroid 5-alpha-reductase [EC:1.3.1.22]
Pathway
ko00905  Brassinosteroid biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00371  Castasterone biosynthesis, campesterol => castasterone
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Metabolism of terpenoids and polyketides
   00905 Brassinosteroid biosynthesis
    K09591  DET2; steroid 5-alpha-reductase
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Other terpenoid biosynthesis
    M00371  Castasterone biosynthesis, campesterol => castasterone
     K09591  DET2; steroid 5-alpha-reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
     K09591  DET2; steroid 5-alpha-reductase
BRITE hierarchy
Other DBs
RN: R07429 R07447
GO: 0047751
Genes
ATH: AT2G38050(DET2)
ALY: ARALYDRAFT_669646
CRB: 17888327
CSAT: 104782237 104785672 104788924 104792598
EUS: EUTSA_v10017092mg
BRP: 103865646
BNA: 106402780 106406145 106406202 106447426 111205507
BOE: 106342103
THJ: 104806524
CPAP: 110814268
CIT: 102609492
TCC: 18597607
GRA: 105779649
DZI: 111294348
EGR: 104441915
VRA: 106764341
VAR: 108328400
CCAJ: 109815063
CAM: 101490577
ADU: 107484826
AIP: 107639500
LJA: Lj0g3v0256849.1(Lj0g3v0256849.1)
LANG: 109360730
FVE: 101295242
PPER: 18775232
PMUM: 103338269
PAVI: 110757320
PXB: 103959591
CSV: 101217020
CMO: 103486328
MCHA: 111015065
CMAX: 111481932
CMOS: 111441400
CPEP: 111790693
RCU: 8273440
JCU: 105646642
JRE: 109004208
VVI: 100261294
SLY: 101256999 543801(det2)
INI: 109160095(PnDET2)
SIND: 105174532
OEU: 111386846
HAN: 110895411
LSV: 111890641
DCR: 108217691
NNU: 104601194
DOSA: Os01t0851600-01(Os01g0851600) Os11t0184100-01(Os11g0184100)
OBR: 102714596
BDI: 100827766
ATS: 109743537(LOC109743537)
SBI: 8058917
ZMA: 100283443
SITA: 101786218
PDA: 103704073
EGU: 105046291
MUS: 103981210
DCT: 110103276
ATR: 18437821
PPP: 112283119
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8602526
  Authors
Li J, Nagpal P, Vitart V, McMorris TC, Chory J
  Title
A role for brassinosteroids in light-dependent development of Arabidopsis.
  Journal
Science 272:398-401 (1996)
DOI:10.1126/science.272.5260.398
Reference
PMID:9108014
  Authors
Li J, Biswas MG, Chao A, Russell DW, Chory J
  Title
Conservation of function between mammalian and plant steroid 5alpha-reductases.
  Journal
Proc Natl Acad Sci U S A 94:3554-9 (1997)
DOI:10.1073/pnas.94.8.3554
  Sequence
[ath:AT2G38050]
Reference
  Authors
Rosati F, Bardazzi I, De Blasi P, Simi L, Scarpi D, Guarna A, Serio M, Racchi ML, Danza G
  Title
5alpha-Reductase activity in Lycopersicon esculentum: cloning and functional characterization of LeDET2 and evidence of the presence of two isoenzymes.
  Journal
J Steroid Biochem Mol Biol 96:287-99 (2005)
DOI:10.1016/j.jsbmb.2005.04.035
  Sequence
[sly:543801]

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