KEGG   ORTHOLOGY: K09593Help
Entry
K09593                      KO                                     

Name
GAB1
Definition
GRB2-associated-binding protein 1
Pathway
ko01521  EGFR tyrosine kinase inhibitor resistance
ko04012  ErbB signaling pathway
ko04014  Ras signaling pathway
ko04072  Phospholipase D signaling pathway
ko04722  Neurotrophin signaling pathway
ko05100  Bacterial invasion of epithelial cells
ko05205  Proteoglycans in cancer
ko05211  Renal cell carcinoma
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Disease
H00605  Deafness, autosomal recessive
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K09593  GAB1; GRB2-associated-binding protein 1
   04012 ErbB signaling pathway
    K09593  GAB1; GRB2-associated-binding protein 1
   04072 Phospholipase D signaling pathway
    K09593  GAB1; GRB2-associated-binding protein 1
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K09593  GAB1; GRB2-associated-binding protein 1
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K09593  GAB1; GRB2-associated-binding protein 1
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K09593  GAB1; GRB2-associated-binding protein 1
   05226 Gastric cancer
    K09593  GAB1; GRB2-associated-binding protein 1
   05211 Renal cell carcinoma
    K09593  GAB1; GRB2-associated-binding protein 1
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    K09593  GAB1; GRB2-associated-binding protein 1
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K09593  GAB1; GRB2-associated-binding protein 1
BRITE hierarchy
Genes
HSA: 2549(GAB1)
PTR: 461516(GAB1)
PPS: 100990740(GAB1)
GGO: 101147447(GAB1)
PON: 100458884(GAB1)
NLE: 100600534(GAB1)
MCC: 700367(GAB1)
MCF: 101865745(GAB1)
CSAB: 103236312(GAB1)
RRO: 104657016(GAB1)
RBB: 108517109(GAB1)
CJC: 100406544(GAB1)
SBQ: 101040995(GAB1)
MMU: 14388(Gab1)
MCAL: 110300068(Gab1)
MPAH: 110337474(Gab1)
RNO: 361388(Gab1)
MUN: 110555404(Gab1)
CGE: 100753832(Gab1)
NGI: 103742387(Gab1)
HGL: 101721604(Gab1)
CCAN: 109693395(Gab1)
OCU: 100346125(GAB1)
TUP: 102497468(GAB1)
CFA: 483808(GAB1)
VVP: 112911650(GAB1)
AML: 100472197(GAB1)
UMR: 103658080(GAB1)
UAH: 113255714(GAB1)
ORO: 101380995(GAB1)
FCA: 101088326(GAB1)
PTG: 102959239(GAB1)
PPAD: 109249832(GAB1)
AJU: 106983704(GAB1)
BTA: 540085(GAB1)
BOM: 102282859(GAB1)
BIU: 109571216(GAB1)
BBUB: 102390621(GAB1)
CHX: 102179970(GAB1)
OAS: 101112165(GAB1)
SSC: 100511026(GAB1)
CFR: 102512457(GAB1)
CDK: 105092112(GAB1)
BACU: 102999413(GAB1)
LVE: 103085000(GAB1)
OOR: 101286927(GAB1)
DLE: 111187768(GAB1)
PCAD: 102991751(GAB1)
ECB: 100062924(GAB1)
EPZ: 103558534(GAB1)
EAI: 106829157(GAB1)
MYB: 102245609(GAB1)
MYD: 102765653(GAB1)
MNA: 107532524(GAB1)
HAI: 109393101(GAB1)
DRO: 112312362(GAB1)
PALE: 102881252(GAB1)
RAY: 107499274(GAB1)
MJV: 108409341(GAB1)
LAV: 100669213(GAB1)
TMU: 101355014
MDO: 100019200(GAB1)
SHR: 100925463(GAB1)
PCW: 110210776(GAB1)
OAA: 100082582(GAB1)
GGA: 422456(GAB1)
MGP: 100543824(GAB1)
CJO: 107313159(GAB1)
NMEL: 110397604(GAB1)
APLA: 101793334(GAB1)
ACYG: 106046685(GAB1)
TGU: 100222864(GAB1)
LSR: 110468511(GAB1)
SCAN: 103822522(GAB1)
GFR: 102039834(GAB1)
FAB: 101813104(GAB1)
PHI: 102108222(GAB1)
PMAJ: 107203076(GAB1)
CCAE: 111928890(GAB1)
CCW: 104697265(GAB1)
ETL: 114058371(GAB1)
FPG: 101920388(GAB1)
FCH: 102060203(GAB1)
CLV: 102099002(GAB1)
EGZ: 104130578(GAB1)
NNI: 104015956(GAB1)
ACUN: 113490468(GAB1)
PADL: 103920892(GAB1)
AAM: 106492079(GAB1)
ASN: 102379491(GAB1)
AMJ: 102574158(GAB1)
PSS: 102458933(GAB1)
CMY: 102930818(GAB1)
CPIC: 101947163(GAB1)
ACS: 100553916(gab1)
PVT: 110073637(GAB1)
PBI: 103059660(GAB1)
PMUR: 107292173(GAB1)
TSR: 106545100(GAB1)
GJA: 107120271(GAB1)
XLA: 734245(gab1.L) 734248(gab1.S)
XTR: 100485031(gab1)
NPR: 108784230(GAB1)
DRE: 406666(gab1)
SANH: 107655091(gab1) 107684448
SGH: 107550557(gab1) 107598765
IPU: 108263355(gab1)
PHYP: 113539859(gab1)
AMEX: 103043031(gab1)
EEE: 113589975(gab1)
TRU: 101067799(gab1) 101078435
LCO: 104917899(gab1) 104932638
NCC: 104964863(gab1)
MZE: 101471751(gab1) 101473094
ONL: 100707394
OLA: 101157091 101173122(gab1)
XMA: 102218636 102230629(gab1)
XCO: 114144325(gab1) 114157718
PRET: 103471132(gab1) 103480707
CVG: 107089396 107103874(gab1)
NFU: 107376790 107389466(gab1)
KMR: 108230340(gab1) 108250222
CSEM: 103383342(gab1)
POV: 109638323(gab1) 109644474
SDU: 111216616(gab1) 111233334
SLAL: 111653595(gab1) 111658585
HCQ: 109511334(gab1) 109511906
BPEC: 110156233(gab1)
MALB: 109955484(gab1) 109973886
SALP: 112079359
ELS: 105007265 105020948(gab1)
SFM: 108924555(gab1) 108936670
LCM: 102356417(GAB1)
CMK: 103181326(gab1)
RTP: 109924954(gab1)
SPU: 100893661
APLC: 110984076
EPA: 110248936
ADF: 107342180
AMIL: 114965006
PDAM: 113681096
SPIS: 111327891
AQU: 105313571
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8596638
  Authors
Holgado-Madruga M, Emlet DR, Moscatello DK, Godwin AK, Wong AJ
  Title
A Grb2-associated docking protein in EGF- and insulin-receptor signalling.
  Journal
Nature 379:560-4 (1996)
DOI:10.1038/379560a0
  Sequence
[hsa:2549]
Reference
  Authors
Aasrum M, Odegard J, Sandnes D, Christoffersen T
  Title
The involvement of the docking protein Gab1 in mitogenic signalling induced by EGF and HGF in rat hepatocytes.
  Journal
Biochim Biophys Acta 1833:3286-94 (2013)
DOI:10.1016/j.bbamcr.2013.10.004
  Sequence
[rno:361388]

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