KEGG   ORTHOLOGY: K10131Help
Entry
K10131                      KO                                     

Name
PMAIP1, NOXA
Definition
phorbol-12-myristate-13-acetate-induced protein 1
Pathway
ko01524  Platinum drug resistance
ko04115  p53 signaling pathway
ko04210  Apoptosis
ko04215  Apoptosis - multiple species
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
ko05210  Colorectal cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
   04215 Apoptosis - multiple species
    K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
   04115 p53 signaling pathway
    K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
   05203 Viral carcinogenesis
    K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
   05210 Colorectal cancer
    K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
  Drug resistance
   01524 Platinum drug resistance
    K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
BRITE hierarchy
Genes
HSA: 5366(PMAIP1)
PTR: 737247(PMAIP1)
PPS: 100979315(PMAIP1)
GGO: 101152154(PMAIP1)
PON: 100457415(PMAIP1)
NLE: 100593765(PMAIP1)
MCC: 702789(PMAIP1)
MCF: 102120192(PMAIP1)
RRO: 104673006(PMAIP1)
RBB: 108526400(PMAIP1)
CJC: 100404690(PMAIP1)
SBQ: 101044364(PMAIP1)
MMU: 58801(Pmaip1)
RNO: 492821(Pmaip1)
CGE: 100755393(Pmaip1)
NGI: 103739615(Pmaip1)
HGL: 106010564(Pmaip1)
CCAN: 109701119(Pmaip1)
OCU: 103349392(PMAIP1)
TUP: 102497162(PMAIP1)
CFA: 100502558(PMAIP1)
AML: 100474991(PMAIP1)
ORO: 101362130(PMAIP1)
FCA: 102900397(PMAIP1)
PTG: 102958923(PMAIP1)
AJU: 106978896(PMAIP1)
BTA: 100296226(PMAIP1)
BOM: 102285398(PMAIP1)
BIU: 109577992(PMAIP1)
PHD: 102331343(PMAIP1)
CHX: 102175063(PMAIP1) 108633288
OAS: 101102359(PMAIP1)
SSC: 397278(PMAIP1)
CFR: 106729352(PMAIP1)
BACU: 103009672(PMAIP1)
OOR: 101269536(PMAIP1)
ECB: 100629496(PMAIP1)
EPZ: 103563750(PMAIP1)
EAI: 106842499(PMAIP1)
MYB: 102246714(PMAIP1)
MYD: 102767454(PMAIP1)
HAI: 109381726(PMAIP1)
RSS: 109446206(PMAIP1)
PALE: 102894490(PMAIP1)
LAV: 100677531(PMAIP1)
TMU: 101345213
GGA: 770077(PMAIP1)
MGP: 104914820(PMAIP1)
CJO: 107305837(PMAIP1)
APLA: 106014526(PMAIP1)
ACYG: 106036301(PMAIP1)
TGU: 105760854(PMAIP1)
GFR: 102043659(PMAIP1)
FAB: 107604289(PMAIP1)
PHI: 102110157(PMAIP1)
PMAJ: 107216430(PMAIP1)
CCW: 104686752(PMAIP1)
FPG: 106112088(PMAIP1)
FCH: 106631015(PMAIP1)
CLV: 102097231(PMAIP1)
EGZ: 104133908(PMAIP1)
AAM: 106499501(PMAIP1)
PSS: 102454201(PMAIP1)
CMY: 102936530(PMAIP1)
CPIC: 101953262(PMAIP1)
PBI: 103049002(PMAIP1)
GJA: 107105807(PMAIP1)
NPR: 108798740(PMAIP1)
DRE: 751765(pmaip1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2398525
  Authors
Hijikata M, Kato N, Sato T, Kagami Y, Shimotohno K
  Title
Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13-acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line.
  Journal
J Virol 64:4632-9 (1990)
  Sequence
[hsa:5366]
Reference
  Authors
Ploner C, Kofler R, Villunger A
  Title
Noxa: at the tip of the balance between life and death.
  Journal
Oncogene 27 Suppl 1:S84-92 (2008)
DOI:10.1038/onc.2009.46
Reference
  Authors
Sun Y, Leaman DW
  Title
Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection.
  Journal
J Biol Chem 280:15561-8 (2005)
DOI:10.1074/jbc.M412630200
  Sequence
[hsa:5366]

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