KEGG ORTHOLOGY: K10168

ORTHOLOGY: K10168

Entry

K10168                      KO

Symbol

TLR5

Name

toll-like receptor 5

Pathway

map04620

Toll-like receptor signaling pathway

map05130

Pathogenic Escherichia coli infection

map05131

Shigellosis

map05132

Salmonella infection

map05134

Legionellosis

map05321

Inflammatory bowel disease

Disease

H00080

Systemic lupus erythematosus

H00311

Legionellosis

H00317

Melioidosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K10168  TLR5; toll-like receptor 5
09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K10168  TLR5; toll-like receptor 5
   05132 Salmonella infection
    K10168  TLR5; toll-like receptor 5
   05131 Shigellosis
    K10168  TLR5; toll-like receptor 5
   05134 Legionellosis
    K10168  TLR5; toll-like receptor 5
  09163 Immune disease
   05321 Inflammatory bowel disease
    K10168  TLR5; toll-like receptor 5
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors
    K10168  TLR5; toll-like receptor 5
Pattern recognition receptors [BR:ko04054]
Membrane-bound pattern recognition receptors
  Toll-like receptors
   K10168  TLR5; toll-like receptor 5

Genes

HSA:	7100(TLR5)

PTR:	457762(TLR5)

PPS:	100987201(TLR5)

GGO:	101142932(TLR5)

PON:	100448609(TLR5)

NLE:	100598559(TLR5)

HMH:	116457771(TLR5)

MCC:	574328(TLR5)

MCF:	102118010(TLR5)

MTHB:

126948340

MNI:	105478117(TLR5)

CSAB:

103230033(TLR5)

CATY:

105576968(TLR5)

PANU:

101025790(TLR5)

TGE:	112633530(TLR5)

MLEU:

105554495(TLR5)

RRO:	104661932(TLR5)

RBB:	108528251(TLR5)

TFN:	117074436(TLR5)

PTEH:

111537097(TLR5)

CANG:

105502820(TLR5)

CJC:	100407519(TLR5)

SBQ:	101037062(TLR5)

CIMI:

108302696(TLR5)

CSYR:

103276839(TLR5)

MMUR:

105863766(TLR5)

LCAT:

123627502(TLR5)

PCOQ:

105810133(TLR5)

OGA:	100944836(TLR5)

MMU:	53791(Tlr5)

MCAL:

110304140(Tlr5)

MPAH:

110322680(Tlr5)

RNO:	289337(Tlr5)

MCOC:

116068152(Tlr5)

ANU:	117712779(Tlr5)

MUN:	110544688(Tlr5)

CGE:	100772103(Tlr5)

MAUA:

101829185(Tlr5)

PROB:

127223724(Tlr5)

PLEU:

114710423(Tlr5)

MORG:

121435754(Tlr5)

MFOT:

126502075

AAMP:

119827571(Tlr5)

NGI:	103726270(Tlr5)

HGL:	101719481(Tlr5)

CCAN:

109692857(Tlr5)

DORD:

105984693(Tlr5)

DSP:	122109447(Tlr5)

PLOP:

125359725(Tlr5)

NCAR:

124961695 124962335

MMMA:

107140519(Tlr5)

OCU:	100350028(TLR5)

OPI:	101533389(TLR5)

TUP:	102478354(TLR5)

GVR:	103597202(TLR5)

CFA:	488605(TLR5)

CLUD:

112642928(TLR5)

VVP:	112912074(TLR5)

VLG:	121471824(TLR5)

NPO:	129515408(TLR5)

AML:	100475654(TLR5)

UMR:	103667333(TLR5)

UAH:	113262895(TLR5)

UAR:	123792070(TLR5)

ELK:

111150868

LLV:

125086131

MPUF:

101693476(TLR5)

MNP:	132025536(TLR5)

MLK:	131814798(TLR5)

NVS:	122918706(TLR5)

ORO:	101363671(TLR5)

EJU:	114215582(TLR5)

ZCA:	113933356(TLR5)

MLX:	118012989(TLR5)

NSU:	110571356(TLR5)

LWW:	102729859(TLR5)

FCA:	101082202(TLR5)

PYU:	121015196(TLR5)

PCOO:

112863197(TLR5)

PBG:	122475589(TLR5)

PVIV:

125159624(TLR5)

LRUF:

124510326

PTG:	102965281(TLR5)

PPAD:

109258909(TLR5)

PUC:

125925059

AJU:

106989362

HHV:	120234151(TLR5)

BTA:	444870(TLR5)

BOM:	102272402(TLR5)

BIU:	109570676(TLR5)

BBUB:

102390405(TLR5)

BBIS:

104997869(TLR5)

CHX:	100860844(TLR5)

OAS:	554256(TLR5)

BTAX:

128061653(TLR5)

ODA:	120880379(TLR5)

CCAD:

122452331(TLR5)

MBEZ:

129551657(TLR5)

SSC:	100144476(TLR5)

CFR:	102522241(TLR5)

CBAI:

105083953(TLR5)

CDK:	105099860(TLR5)

VPC:	102532318(TLR5)

BACU:

103014154(TLR5)

BMUS:

118886545(TLR5)

LVE:	103072186(TLR5)

OOR:	101271021(TLR5)

DLE:	111177501(TLR5)

PCAD:

102983296(TLR5)

PSIU:

116762648(TLR5)

NASI:

112403131(TLR5)

ECB:	111771347(TLR5)

EPZ:	103559682(TLR5)

EAI:	106829548(TLR5)

MYB:	102258326(TLR5)

MYD:	102775427(TLR5)

MMYO:

118678895(TLR5)

MLF:	102431957(TLR5)

PKL:	118727639(TLR5)

EFUS:

103293531(TLR5)

MNA:	107543589(TLR5)

DRO:	112318779(TLR5)

SHON:

119003188(TLR5)

AJM:	119036537(TLR5)

PDIC:

114512329(TLR5)

PHAS:

123833298(TLR5)

MMF:	118640576(TLR5)

PPAM:

129072880(TLR5)

HAI:	109381203(TLR5)

RFQ:	117018627(TLR5)

PALE:

102897940(TLR5)

PGIG:

120619150(TLR5)

PVP:	105292593(TLR5)

RAY:	107498976(TLR5)

TOD:	119244501(TLR5)

SARA:

101542032(TLR5)

SETR:

126013389(TLR5)

LAV:	100664656(TLR5)

TMU:

101355097

ETF:	101648009(TLR5)

DNM:

101428112

MDO:	100025157(TLR5)

GAS:	123244765(TLR5)

SHR:	100919596(TLR5)

AFZ:

127559519

PCW:	110205540(TLR5)

OAA:	100081435 100081459

GGA:	554217(TLR5)

PCOC:

116230880(TLR5)

MGP:	100546336(TLR5)

CJO:	107311034(TLR5)

TPAI:

128074674(TLR5)

LMUT:

125690015(TLR5)

NMEL:

110397215(TLR5)

APLA:

101797832(TLR5)

ACYG:

106031551(TLR5)

CATA:

118253844(TLR5)

AFUL:

116487020(TLR5)

TGU:	100218143(TLR5)

LSR:	110483103(TLR5)

PMOA:

120500655(TLR5)

OTC:	121336452(TLR5)

PRUF:

121355694(TLR5)

GFR:	102042378(TLR5)

FAB:	101810099(TLR5)

OMA:	130251691(TLR5)

PHI:	102111933(TLR5)

PMAJ:

107201155(TLR5)

CCAE:

111926244(TLR5)

CCW:	104685614(TLR5)

CBRC:

103612653(TLR5)

ETL:	114066646(TLR5)

ZAB:	102071973(TLR5)

SVG:	106853945(TLR5)

MMEA:

130579847(TLR5)

HRT:	120751330(TLR5)

FPG:	101916146(TLR5)

FCH:	102046548(TLR5)

CLV:	102089513(TLR5)

EGZ:	104124726(TLR5)

NNI:	104019645(TLR5)

PCRI:

104032919(TLR5)

PLET:

104627104(TLR5)

EHS:	104509523(TLR5)

PCAO:

104052596(TLR5)

ACUN:

113477685(TLR5)

TALA:

104362353(TLR5)

PADL:

103925024(TLR5)

AFOR:

103896005(TLR5)

ACHC:

115350015(TLR5)

HALD:

104324384(TLR5)

HLE:	104838129(TLR5)

AGEN:

126052579

GCL:

127014503

CCRI:

104166990(TLR5)

CSTI:

104559465(TLR5)

CMAC:

104479002(TLR5)

MUI:	104548265(TLR5)

BREG:

104634724(TLR5)

FGA:	104072809(TLR5)

GSTE:

104264431(TLR5)

LDI:	104346252(TLR5)

MNB:	103782440(TLR5)

OHA:	104331971(TLR5)

NNT:	104410671(TLR5)

SHAB:

115614025(TLR5)

DPUB:

104300911(TLR5)

PGUU:

104462625(TLR5)

ACAR:

104522145(TLR5)

AVIT:

104271393(TLR5)

CVF:	104294663(TLR5)

RTD:	128907080(TLR5)

CUCA:

104067028(TLR5)

TEO:	104372400(TLR5)

BRHI:

104497078(TLR5)

AROW:

112961102(TLR5)

NPD:	112954833(TLR5)

TGT:	104570279(TLR5)

DNE:	112980101(TLR5)

SCAM:

104151695(TLR5)

ASN:	102380505(TLR5) 102387718

AMJ:	102565988(TLR5) 102571488

CPOO:

109319758(TLR5)

GGN:	109296884(TLR5)

PSS:	102460005(TLR5) 102463208

CMY:	102935193 102946664(TLR5)

CCAY:

125633667(TLR5) 125639787

DCC:	119853163(TLR5) 119858713

CPIC:

101937248 101941545(TLR5)

TST:	117874487(TLR5) 117881017

CABI:

116829247(TLR5) 116835075

MRV:	120402053(TLR5) 120408927

ACS:	100561217(tlr5) 100562658

ASAO:

132761389(TLR5) 132764541

PVT:	110069864 110075393(TLR5)

SUND:

121915386 121916087(TLR5)

PBI:	103050967 103053936(TLR5)

PMUR:

107295996 107302774(TLR5)

CTIG:

120307207(TLR5) 120314894

TSR:	106538667(TLR5)

PGUT:

117657680 117671746(TLR5)

APRI:

131186688 131189338(TLR5)

PTEX:

113433243(TLR5) 113447432

NSS:	113421742(TLR5) 113423841

VKO:	123024573(TLR5)

PMUA:

114586969 114594635(TLR5)

PRAF:

128404174 128411091(TLR5)

ZVI:	118076577 118083205(TLR5)

HCG:	128337378 128350290(TLR5)

GJA:	107110111 107121624(TLR5)

STOW:

125436322(TLR5) 125437064

EMC:	129325287 129341772(TLR5)

XLA:	495313(tlr5.L) 733314(tlrs5.L)

XTR:	100489423 100496647

NPR:	108785250 108801303(TLR5)

RTEM:

120917332 120937850 120937851(TLR5)

BBUF:

120980705 120999592(TLR5)

BGAR:

122920370 122934690(TLR5)

MUO:	115465485(TLR5) 115481045

GSH:	117357562(TLR5) 117364506

DRE:	403138(tlr5a) 403139(tlr5b)

SRX:	107712571 107712572

SANH:

107669443

SGH:	107559110 107559111

CAUA:

CGIB:

PTET:

LROH:

OMC:	131527554 131527555

MAMB:

125278549 125278550

CIDE:

127501828 127501829

MASI:

127409613 127416299

MANU:

129429835(tlr5b) 129429836(tlr5a)

IPU:	100304981(tlr-5) 108275971 108275978

IFU:	128603241 128603259 128603273

SMEO:

124396893 124396895 124396896

TFD:	113635777 113635787

TVC:	132861000 132861001

AMEX:

103047589

CMAO:

118820884

EEE:	113571833(tlr5)

CHAR:

105899408(tlr5a) 105899424

TRU:	101062562 101066893(tlr5)

TFS:	130515868 130516292 130520791

TNG:	GSTEN00011330G001 GSTEN00035423G001

LCO:

104926138

NCC:	104954604(tlr5) 104962127

TBEN:

117486873 117498574

CGOB:

115028858(tlr5)

PGEO:

117439517 117440165

GACU:

117532795 117554374

EMAC:

134876651(tlr5a) 134876748

ELY:	117270374 117270621

EFO:	125896929 125897360

PLEP:

121955398 121955440

SLUC:

116047007(tlr5a) 116066344

ECRA:

117941168 117961256(tlr5b)

ESP:	116706584(tlr5)

PFLV:

114572861 114573305(tlr5)

GAT:	120807964 120808512

PPUG:

119194857 119195259

AFB:	129106948 129106989

CLUM:

117727165 117727225

PSWI:

130202930

MSAM:

119908929(tlr5a)

SCHU:

122863272 122863659

CUD:	121521341 121521699(tlr5a)

ALAT:

119012661 119012751(tlr5a)

MZE:	101475838 101486268

ONL:	100702807 100711546(tlr5)

OAU:	116311486 116328233

OLA:	101157992 101166842

OML:	112158097 112158546

CSAI:

133464451 133464576

XMA:	102232760(tlr5) 102234695

XCO:	114158224 114158561(tlr5)

XHE:	116733827(tlr5) 116734202

PRET:

103457760(tlr5)

PFOR:

103148807(tlr5)

PLAI:

106944991(tlr5) 106945225

PMEI:

106907834(tlr5)

GAF:	122825121 122825391(tlr5a)

PPRL:

129369026 129375280

CVG:	107082844 107105199(tlr5)

CTUL:

119772558(tlr5a) 119778367

GMU:	124881608 124882491

NFU:	107377778 107378245(tlr5)

KMR:	108233378 108245476(tlr5a)

ALIM:

106526882(tlr5) 106532847

NWH:	119418350 119418747(tlr5a)

AOCE:

111571287

MCEP:

124999336(tlr5a)

CSEM:

103381117 103398497

POV:	109632509(tlr5) 109643067

SSEN:

122783742 122783817

HHIP:

117758514(tlr5a) 117758541

HSP:	118099099 118099923(tlr5a)

SMAU:

118290534 118290653

LCF:	108888912 108895804 108895805

SDU:	111236470 111238028(tlr5)

SLAL:

111661380(tlr5)

HCQ:	109528314 109531751(tlr5)

SSCV:

125990087 125990132

SBIA:

133496165 133496356

PEE:	133417226 133417338(tlr5a)

PTAO:

133468576(tlr5a) 133468727

BPEC:

110158930(tlr5) 110175322

MALB:

109962273 109969830(tlr5)

BSPL:

114849590 114850172

SJO:	128376748 128376950 128377160

SASA:

100136921(tl/lrr) 106571469(tlr5) 106572741

STRU:

115165433 115174711(tlr5)

OTW:	112216386 112250380

OMY:	100135812(tlr5) 100137014(tlr5m)

OGO:	123990811 124023213

ONE:	115104691 115107828(tlr5)

OKI:	109900807(tlr5) 109908346

OKE:	118373031 118398593

SALP:

111966846 112068708(tlr5)

SNH:	120024076 120024619 120024620 120059110

CCLU:

121537831 121552497

ELS:	105023796 105023856

SFM:	108929385(tlr5)

PKI:	111837524(tlr5)

AANG:

118232444

LOC:	102693268(tlr5)

PSPA:

121317074

ARUT:

117410752 117969683 117969687

PSEX:

120522541 120539344

LCM:

102366872

CPLA:

122546976 122547751

HOC:	132835073(tlr5b)

PMRN:

LRJ:

PVUL:

GAE:

HRF:	124112884 124149785

HRJ:	124289107 124292462

CVN:

111103359

CANU:

128183459

OED:	125652264 125652267 125652270

» show all

Reference

PMID:16410796

Authors

Kawai T, Akira S

Title

TLR signaling.

Journal

Cell Death Differ 13:816-25 (2006)
DOI:10.1038/sj.cdd.4401850

Reference

PMID:11323673

Authors

Hayashi F, Smith KD, Ozinsky A, Hawn TR, Yi EC, Goodlett DR, Eng JK, Akira S, Underhill DM, Aderem A

Title

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5.

Journal

Nature 410:1099-103 (2001)
DOI:10.1038/35074106

Sequence

[hsa:7100]

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