KEGG ORTHOLOGY: K10344

ORTHOLOGY: K10344

Entry

K10344                      KO

Symbol

SPSB2, SSB2

Name

SPRY domain-containing SOCS box protein 2

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10344  SPSB2, SSB2; SPRY domain-containing SOCS box protein 2
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul5 complex
    Target recognizing subunit
     K10344  SPSB2, SSB2; SPRY domain-containing SOCS box protein 2

Genes

HSA:	84727(SPSB2)

PTR:	451800(SPSB2)

PPS:	100969185(SPSB2)

GGO:	101135250(SPSB2)

PON:	100454595(SPSB2)

NLE:	100589772(SPSB2)

HMH:	116472609(SPSB2)

MCC:	714158(SPSB2)

MCF:	102127864(SPSB2)

MTHB:

126930454

MNI:	105484210(SPSB2)

CSAB:

103218485(SPSB2)

CATY:

105583040(SPSB2)

PANU:

100999126(SPSB2)

TGE:	112634144(SPSB2)

MLEU:

105541808(SPSB2)

RRO:	104680092(SPSB2)

RBB:	108542038(SPSB2)

TFN:	117090620(SPSB2)

PTEH:

111555919(SPSB2)

CANG:

105521224(SPSB2)

CJC:	100408786(SPSB2)

SBQ:	101031057(SPSB2)

CIMI:

108294999(SPSB2)

MMUR:

105869003(SPSB2)

LCAT:

123640098(SPSB2)

PCOQ:

105805041(SPSB2)

OGA:	100950329(SPSB2)

MMU:	14794(Spsb2)

MCAL:

110295999(Spsb2)

MPAH:

110315979(Spsb2)

RNO:	297592(Spsb2)

MCOC:

116099576(Spsb2)

ANU:	117715412(Spsb2)

MUN:	110548559(Spsb2)

CGE:	100757837(Spsb2)

MAUA:

101843554(Spsb2)

PROB:

127213043(Spsb2)

PLEU:

114708802(Spsb2)

MORG:

121439194(Spsb2)

MFOT:

126514884

AAMP:

119807626(Spsb2)

NGI:	103727498(Spsb2)

HGL:	101721356(Spsb2)

CPOC:

100724255(Spsb2)

CCAN:

109682810(Spsb2)

NCAR:

124983398

OCU:

100348566

OPI:	101516865(SPSB2)

TUP:	102502132(SPSB2)

GVR:	103586403(SPSB2)

CFA:	477710(SPSB2)

CLUD:

112675359(SPSB2)

VVP:	112917334(SPSB2)

VLG:	121479879(SPSB2)

NPO:	129503496(SPSB2)

AML:	100474555(SPSB2)

UMR:	103656183(SPSB2)

UAH:	113257955(SPSB2)

UAR:	123781648(SPSB2)

ELK:

111159755

LLV:

125106054

MPUF:

101680735(SPSB2)

NVS:	122891443(SPSB2)

ORO:	101373209(SPSB2)

EJU:	114222466(SPSB2)

ZCA:	113921352(SPSB2)

MLX:	118025722(SPSB2)

NSU:	110581077(SPSB2)

LWW:	102733886(SPSB2)

FCA:	101086156(SPSB2)

PYU:	121022126(SPSB2)

PCOO:

112867311(SPSB2)

PBG:	122472385(SPSB2)

LRUF:

124501666

PTG:	102952090(SPSB2)

PPAD:

109276103(SPSB2)

PUC:	125917984 125917994

AJU:

106965346

HHV:	120220438(SPSB2)

BTA:	613651(SPSB2)

BOM:	102282784(SPSB2)

BIU:	109558917(SPSB2)

BBUB:

102394822(SPSB2)

BBIS:

104992174(SPSB2)

CHX:	102168705(SPSB2)

OAS:	101102799(SPSB2)

BTAX:

128048327(SPSB2)

ODA:	120858741(SPSB2)

CCAD:

122423974(SPSB2)

MBEZ:

129536800(SPSB2)

SSC:	100152120(SPSB2)

CFR:	102510575(SPSB2)

CBAI:

105071084(SPSB2)

CDK:	105098200(SPSB2)

VPC:	102531957(SPSB2)

BACU:

103007022(SPSB2)

LVE:	103071634(SPSB2)

OOR:	101287416(SPSB2)

DLE:	111176698(SPSB2)

PCAD:

102983995(SPSB2)

PSIU:

116760891(SPSB2)

NASI:

112391843(SPSB2)

ECB:	111773910(SPSB2)

EPZ:	103547021(SPSB2)

EAI:	106847321(SPSB2)

MYB:	102260340(SPSB2)

MYD:	102758065(SPSB2)

MMYO:

118649726(SPSB2)

MNA:	107544006(SPSB2)

PKL:	118730182(SPSB2)

EFUS:

103289031(SPSB2)

HAI:	109373681(SPSB2)

DRO:	112321841(SPSB2)

SHON:

119002210(SPSB2)

AJM:	119060318(SPSB2)

PDIC:

114514067(SPSB2)

PHAS:

123810557(SPSB2)

MMF:	118624144(SPSB2)

RFQ:	117028941(SPSB2)

PALE:

102894495(SPSB2)

PGIG:

120611666(SPSB2)

PVP:	105295947(SPSB2)

RAY:	107519798(SPSB2)

MJV:	108389829(SPSB2)

TOD:	119247769(SPSB2)

SARA:

101548229(SPSB2)

LAV:	100676139(SPSB2)

TMU:

101356503

ETF:	101639111(SPSB2)

DNM:	101443259(SPSB2)

GAS:	123248902(SPSB2)

SHR:	100915695(SPSB2)

AFZ:

127539241

PCW:	110213793(SPSB2)

OAA:	114807812(SPSB2)

EEE:

SASA:

OTW:

SALP:

PSEX:

LCM:	102367072(SPSB2)

HRJ:

CVN:

PMAX:

Reference

PMID:15601820

Authors

Kamura T, Maenaka K, Kotoshiba S, Matsumoto M, Kohda D, Conaway RC, Conaway JW, Nakayama KI.

Title

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.

Journal

Genes Dev 18:3055-65 (2004)
DOI:10.1101/gad.1252404

Sequence

[hsa:84727]

All links

Ontology (2)   
   KEGG BRITE (2)   
Gene (173)   
   KEGG GENES (146)   
   KEGG MGENES (3)   
   RefGene (22)   
   OC (2)   
Literature (1)   
   PubMed (1)   
All databases (176)   

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