KEGG   ORTHOLOGY: K10357Help
Entry
K10357                      KO                                     

Name
MYO5
Definition
myosin V
Disease
H00101  Other phagocyte defects
H01174  Congenital diarrhea
H02022  Griscelli syndrome
Brite
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   Factors involved in mRNA localization
    Cargo complex
     K10357  MYO5; myosin V
   mRNA cycle factors
    P-body specific factors
     K10357  MYO5; myosin V
Membrane trafficking [BR:ko04131]
 Others
  Actin-binding proteins
   Myosins
    K10357  MYO5; myosin V
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Mitochondrial dynamics
   Retention of mitochondria
    K10357  MYO5; myosin V
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K10357  MYO5; myosin V
BRITE hierarchy
Genes
HSA: 4644(MYO5A) 4645(MYO5B) 55930(MYO5C)
PTR: 450136(MYO5A) 453441(MYO5C) 455415(MYO5B)
PPS: 100983158(MYO5C) 100983500(MYO5A) 100986174(MYO5B)
GGO: 101125567(MYO5B) 101135093 101145663(MYO5A) 101149001(MYO5C)
PON: 100434994(MYO5B) 100446765(MYO5C) 103892519(MYO5A)
NLE: 100580623(MYO5B) 100594716(MYO5C) 100595056(MYO5A)
MCC: 574273(MYO5A) 695333(MYO5C) 699592(MYO5B)
MCF: 101926463(MYO5A) 102125938(MYO5B) 102127160(MYO5C)
CSAB: 103222428(MYO5B) 103245607(MYO5A) 103245609(MYO5C)
RRO: 104656839(MYO5B) 104660904(MYO5A) 104660906(MYO5C)
RBB: 108538118(MYO5A) 108538177(MYO5C) 108539751(MYO5B)
CJC: 100385252(MYO5C) 100394767(MYO5A) 100406508(MYO5B)
SBQ: 101031138(MYO5C) 101031751(MYO5A) 101036063(MYO5B)
MMU: 17918(Myo5a) 17919(Myo5b) 208943(Myo5c)
RNO: 25017(Myo5a) 25132(Myo5b) 315820(Myo5c)
CGE: 100753160(Myo5c) 100753457(Myo5a) 100765544(Myo5b)
NGI: 103724573(Myo5b) 103731408(Myo5a) 103731422(Myo5c)
HGL: 101697151(Myo5a) 101698272(Myo5c) 101722462(Myo5b)
CCAN: 109695551(Myo5a) 109695552(Myo5c) 109698176(Myo5b)
OCU: 100008736(MYO5B) 100346225(MYO5A) 100346740(MYO5C)
TUP: 102473487(MYO5B) 102486748(MYO5A) 102487144(MYO5C)
CFA: 478312(MYO5A) 480220(MYO5B) 487555(MYO5C)
AML: 100467505(MYO5C) 100467758(MYO5A) 100476593(MYO5B)
UMR: 103665214(MYO5B) 103676840(MYO5C) 103676841(MYO5A)
ORO: 101362599(MYO5C) 101362897(MYO5A) 101380619(MYO5B)
FCA: 101081303(MYO5A) 101081552(MYO5C) 101094380(MYO5B)
PTG: 102955237(MYO5C) 102955519(MYO5A) 102967215(MYO5B)
AJU: 106967265(MYO5C) 106967266(MYO5A) 106974942(MYO5B)
BTA: 514078(MYO5B) 532574(MYO5C) 541234(MYO5A)
BOM: 102270427(MYO5B) 102279375(MYO5C) 102285406(MYO5A) 102285696(Myosin-Vc)
PHD: 102320272(MYO5B) 102320470(MYO5A) 102320836(MYO5C)
CHX: 102168225(MYO5B) 102168636(MYO5C) 102174306(MYO5A)
OAS: 101105758(MYO5A) 101106017(MYO5C) 101112182(MYO5B)
SSC: 100155557(MYO5C) 100521829(MYO5B) 594849(MYO5A)
CFR: 102509893(MYO5A) 102510434(MYO5C) 102510976(MYO5B)
BACU: 103000625(MYO5C) 103001276(MYO5A) 103009216(MYO5B)
LVE: 103089376(MYO5C) 103089568(MYO5B) 103091126(MYO5A)
OOR: 101269592(MYO5A) 101269838(MYO5C) 101280813(MYO5B)
ECB: 100069390(MYO5B) 100069548(MYO5A) 100069562(MYO5C)
EPZ: 103547457(MYO5B) 103548459(MYO5C) 103548467(MYO5A)
EAI: 106834594(MYO5B) 106837145(MYO5C) 106837146(MYO5A)
MYB: 102242127(MYO5A) 102242423(MYO5C) 102254879(MYO5B)
MYD: 102762165(MYO5B) 102764503(MYO5A) 102764790(MYO5C)
HAI: 109376903(MYO5B) 109394211(MYO5C) 109394220(MYO5A)
RSS: 109441287(MYO5B) 109455489(MYO5A) 109455495(MYO5C)
PALE: 102895610(MYO5B) 102898214(MYO5A) 102898466(MYO5C)
LAV: 100669551(MYO5B) 100674954(MYO5C) 100675241(MYO5A)
MDO: 100020194(MYO5B) 100031389(MYO5C) 100031404(MYO5A)
SHR: 100913898(MYO5C) 100914159(MYO5A) 100920694(MYO5B)
OAA: 100092139(MYO5C) 100092156(MYO5A)
GGA: 396237(MYO5A) 430027(MYO5C) 430317(MYO5B)
CJO: 107318692(MYO5A) 107318694(MYO5C) 107325605
APLA: 101791989(MYO5B) 101798412(MYO5A) 101798589(MYO5C) 101803079(Myosin-Vb)
ACYG: 106033664(MYO5C) 106033668(MYO5A) 106037342(MYO5B) 106045646
TGU: 100221573(MYO5C) 100222193(MYO5B) 100225447(MYO5A)
GFR: 102034681(MYO5B) 102040656(MYO5C) 102041729(MYO5A)
FAB: 101807328(MYO5A) 101810622(MYO5C) 101821093(MYO5B)
PHI: 102099388(MYO5A) 102099569(MYO5C) 102104960(MYO5B)
PMAJ: 107198250(MYO5B) 107209410(MYO5C) 107209433(MYO5A)
CCW: 104684109(MYO5C) 104684111(MYO5A) 104686725(MYO5B)
FPG: 101912519 101913110(MYO5A) 101913279(MYO5C) 101921015(MYO5B)
FCH: 102048654(MYO5B) 102054664 102056876(MYO5A) 102057049(MYO5C)
CLV: 102090187(MYO5C) 102090369(MYO5A) 102091390(MYO5B) 102094589
EGZ: 104126333 104130782(MYO5A) 104130783(MYO5C) 104134190(MYO5B)
AAM: 106484091 106487891(MYO5B) 106496392(MYO5A) 106496394(MYO5C)
ASN: 102368182(MYO5C) 102375640(MYO5B) 102376880 102378719 102382119(MYO5A)
AMJ: 102563609(MYO5C) 102563838(MYO5B) 102564065(MYO5A) 102577330
PSS: 102444310 102446200(MYO5A) 102447990(MYO5C) 102455112(MYO5B)
CMY: 102938231(MYO5B) 102940065(MYO5C) 102940287(MYO5A)
CPIC: 101934774 101948493(MYO5B) 101949090(MYO5C) 101949354(MYO5A) 101952276
ACS: 100553759 100565457(myo5c) 100565658(myo5a) 103280680(myo5b)
PVT: 110077240(MYO5A) 110077263(MYO5C) 110090043(MYO5B)
PBI: 103049653(MYO5B) 103053038(MYO5A) 103053748(MYO5C)
XLA: 108705475 108711384(myo5c.L) 108712922 108718627 380409(myo5a.L)
XTR: 100379760(myo5b) 100495210(myo5c) 100495365(myo5a)
NPR: 108790686(MYO5B) 108804209(MYO5C) 108804358(MYO5A)
DRE: 562188(myo5aa) 562676(myo5c) 565267(myo5ab) 567402(myo5b)
IPU: 108264474(myo5a) 108270951 108275348(myo5c) 108275443 108279397(myo5b)
LCO: 104921041 104926382(myo5a) 104932823(myo5c) 104936392(myo5b) 109141087
MZE: 101466400(myo5c) 101466683 101472368(myo5b) 101480822(myo5a) 101482435
OLA: 101162444(myo5c) 101165221 101168277(myo5a) 101171723(myo5b) 101173462
XMA: 102217816(myo5b) 102219593 102219846(myo5c) 102225555(myo5a) 102234667
BPEC: 110161435(myo5b) 110169598 110169599(myo5c) 110174026 110175253(myo5a)
SFM: 108919800 108926693(myo5c) 108926730(myo5a) 108929055 108935333(myo5b)
LCM: 102358513(MYO5B) 102359539(MYO5A) 102359809(MYO5C) 102360809
CMK: 103186880(myo5c) 103186886(myo5a) 103187356(myo5b) 103189695
CIN: 100186725
SPU: 373234
APLC: 110974492
DME: Dmel_CG2146(didum)
DSI: Dsimw501_GD10485(Dsim_GD10485)
MDE: 101894659
AAG: 5571874
AME: 726456(Myo5)
BIM: 100743525
BTER: 100644655
SOC: 105207391
AEC: 105153022
ACEP: 105622890
PBAR: 105434225
HST: 105191851(Myosin-Va)
LHU: 105679451
PGC: 109856506
NVI: 100120420(Myo5)
TCA: 663516(Myo5)
DPA: 109536306
BMOR: 101736113
PMAC: 106709467
PRAP: 110992647
DNX: 107169347
ZNE: 110831596
FCD: 110849439
TUT: 107361227
CEL: CELE_F36D4.3(hum-2)
CBR: CBG19269(Cbr-hum-2)
BMY: Bm1_18445
TSP: Tsp_10363
MYI: 110445410
OBI: 106873192
EPA: 110237605
ADF: 107347060
HMG: 100205824(myo5c) 101235322
ATH: AT1G17580(MYA1) AT2G31900(XIF) AT4G33200(XI-I) AT5G54280(ATM2)
LJA: Lj0g3v0047839.3(Lj0g3v0047839.3) Lj0g3v0296779.1(Lj0g3v0296779.1) Lj4g3v2178110.2(Lj4g3v2178110.2)
DOSA: Os01t0713900-01(Os01g0713900) Os02t0777700-00(Os02g0777700) Os02t0816900-01(Os02g0816900) Os03t0747900-00(Os03g0747900) Os03t0860700-00(Os03g0860700) Os05t0537200-01(Os05g0537200) Os06t0488200-01(Os06g0488200) Os07t0562800-01(Os07g0562800) Os10t0339400-01(Os10g0339400) Os10t0395100-01(Os10g0395100) Os10t0395150-00(Os10g0395150)
ATS: 109731850(LOC109731850) 109732739(LOC109732739) 109740013(LOC109740013) 109746682(LOC109746682) 109751364(LOC109751364) 109755475(LOC109755475) 109757483(LOC109757483) 109763857(LOC109763857) 109766321(LOC109766321) 109781132(LOC109781132)
SCE: YAL029C(MYO4) YOR326W(MYO2)
ERC: Ecym_5067
KMX: KLMA_50113(MYO2)
NCS: NCAS_0F01740(NCAS0F01740) NCAS_0I00130(NCAS0I00130)
NDI: NDAI_0A08650(NDAI0A08650) NDAI_0H02590(NDAI0H02590)
TPF: TPHA_0I00510(TPHA0I00510) TPHA_0N00540(TPHA0N00540)
TBL: TBLA_0E02420(TBLA0E02420)
TDL: TDEL_0H03830(TDEL0H03830)
KAF: KAFR_0D01140(KAFR0D01140) KAFR_0K00600(KAFR0K00600)
PIC: PICST_75361(MYO2)
CAL: CAALFM_C113780WA(MYO2)
CAUR: QG37_03375
SLB: AWJ20_1099(MYO2)
NCR: NCU01440
NTE: NEUTE1DRAFT143891(NEUTE1DRAFT_143891)
MGR: MGG_16213
MAW: MAC_02395
MAJ: MAA_06844
CMT: CCM_03939
BFU: BCIN_03g06080(Bcmyo2)
MBE: MBM_08256
ANI: AN8862.2
ANG: ANI_1_338154(An17g02290)
PBL: PAAG_12619(PAAG_08697)
ABE: ARB_00886
TVE: TRV_07927
PTE: PTT_19470
SPO: SPBC2D10.14c(myo51) SPCC1919.10c(myo52)
CNE: CND05780
ABP: AGABI1DRAFT118343(AGABI1DRAFT_118343)
ABV: AGABI2DRAFT183448(AGABI2DRAFT_183448)
MGL: MGL_0033
DDI: DDB_G0289447(myoH)
DFA: DFA_06385(myoJ) DFA_09266(myoH)
PYO: PY17X_1348900(PY01039)
SMIN: v1.2.013164.t1(symbB.v1.2.013164.t1) v1.2.013164.t2(symbB.v1.2.013164.t2) v1.2.018616.t1(symbB.v1.2.018616.t1) v1.2.024273.t1(symbB.v1.2.024273.t1) v1.2.028341.t1(symbB.v1.2.028341.t1) v1.2.028343.t1(symbB.v1.2.028343.t1) v1.2.032819.t1(symbB.v1.2.032819.t1) v1.2.037350.t1(symbB.v1.2.037350.t1) v1.2.038214.t1(symbB.v1.2.038214.t1)
PTI: PHATRDRAFT_432(myoA4) PHATRDRAFT_54688(myoA3)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Mehta AD, Rock RS, Rief M, Spudich JA, Mooseker MS, Cheney RE
  Title
Myosin-V is a processive actin-based motor.
  Journal
Nature 400:590-3 (1999)
DOI:10.1038/23072
  Sequence
[hsa:4644]
Reference
  Authors
Swiatecka-Urban A, Talebian L, Kanno E, Moreau-Marquis S, Coutermarsh B, Hansen K, Karlson KH, Barnaby R, Cheney RE, Langford GM, Fukuda M, Stanton BA
  Title
Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells.
  Journal
J Biol Chem 282:23725-36 (2007)
DOI:10.1074/jbc.M608531200
  Sequence
[hsa:4645]
Reference
  Authors
Munchow S, Sauter C, Jansen RP
  Title
Association of the class V myosin Myo4p with a localised messenger RNA in budding yeast depends on She proteins.
  Journal
J Cell Sci 112 ( Pt 10):1511-8 (1999)
  Sequence
[sce:YAL029C]
Reference
  Authors
Rossi G, Brennwald P
  Title
Yeast homologues of lethal giant larvae and type V myosin cooperate in the regulation of Rab-dependent vesicle clustering and polarized exocytosis.
  Journal
Mol Biol Cell 22:842-57 (2011)
DOI:10.1091/mbc.E10-07-0570
  Sequence
[sce:YOR326W]

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