KEGG   ORTHOLOGY: K10568Help
Entry
K10568                      KO                                     

Name
NEIL2
Definition
endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]
Pathway
ko03410  Base excision repair
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    K10568  NEIL2; endonuclease VIII-like 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K10568  NEIL2; endonuclease VIII-like 2
Enzymes [BR:ko01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.2  Hydrolysing N-glycosyl compounds
    3.2.2.-  
     K10568  NEIL2; endonuclease VIII-like 2
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.99  Other carbon-oxygen lyases
    4.2.99.18  DNA-(apurinic or apyrimidinic site) lyase
     K10568  NEIL2; endonuclease VIII-like 2
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA glycosylases
     K10568  NEIL2; endonuclease VIII-like 2
BRITE hierarchy
Genes
HSA: 252969(NEIL2)
PTR: 463992(NEIL2)
PPS: 100988715(NEIL2)
GGO: 101150242(NEIL2)
PON: 100172638(NEIL2)
NLE: 100602769(NEIL2)
MCC: 696647(NEIL2)
MCF: 102132832(NEIL2)
CSAB: 103215321(NEIL2)
RRO: 104679112(NEIL2)
RBB: 108536703(NEIL2)
CJC: 100411828(NEIL2)
SBQ: 101047566(NEIL2)
MMU: 382913(Neil2)
RNO: 305957(Neil2)
CGE: 100756411(Neil2)
NGI: 103729975(Neil2)
HGL: 101708646(Neil2)
CCAN: 109693541(Neil2)
OCU: 100358670(NEIL2)
TUP: 102483174(NEIL2)
CFA: 486078(NEIL2)
AML: 100478088(NEIL2)
UMR: 103675933(NEIL2)
ORO: 101376483(NEIL2)
FCA: 101084357(NEIL2)
PTG: 102968160(NEIL2)
AJU: 106975820(NEIL2)
BTA: 444987(NEIL2)
BOM: 102284355(NEIL2)
BIU: 109562777(NEIL2)
PHD: 102344650(NEIL2)
OAS: 101118667(NEIL2)
SSC: 100624483(NEIL2)
CFR: 102523191(NEIL2)
CDK: 105101910(NEIL2)
BACU: 102999970(NEIL2)
LVE: 103069912(NEIL2)
OOR: 101287746(NEIL2)
ECB: 100065246(NEIL2)
EPZ: 103558183(NEIL2)
EAI: 106822583(NEIL2)
MYB: 102240063(NEIL2)
MYD: 102770628(NEIL2)
HAI: 109379512(NEIL2)
RSS: 109448133(NEIL2)
PALE: 102882777(NEIL2)
TMU: 101346506
MDO: 100032683(NEIL2)
SHR: 100922780(NEIL2)
OAA: 100092479(NEIL2)
GGA: 422037(NEIL2)
MGP: 100545517(NEIL2)
CJO: 107312395(NEIL2)
APLA: 101796576(NEIL2)
ACYG: 106038132(NEIL2)
TGU: 100226151(NEIL2)
GFR: 102034796(NEIL2)
FAB: 101816176(NEIL2)
PHI: 102107621(NEIL2)
PMAJ: 107201197(NEIL2)
CCW: 104696891(NEIL2)
FPG: 101916591(NEIL2)
FCH: 102049780(NEIL2)
CLV: 102085121(NEIL2) 102093681
EGZ: 104127274(NEIL2)
AAM: 106483923(NEIL2)
ASN: 102373650(NEIL2)
AMJ: 102568962(NEIL2)
PSS: 102452291(NEIL2)
CMY: 102931564(NEIL2)
CPIC: 101945638(NEIL2)
ACS: 100553937(neil2)
PBI: 103052360(NEIL2)
GJA: 107105419(NEIL2)
XLA: 108717236
XTR: 100135209(neil2) 100491264
NPR: 108797916(NEIL2)
SPU: 105445024
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Dou H, Mitra S, Hazra TK
  Title
Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2.
  Journal
J Biol Chem 278:49679-84 (2003)
DOI:10.1074/jbc.M308658200
  Sequence
[hsa:252969]
Reference
  Authors
Bhakat KK, Hazra TK, Mitra S
  Title
Acetylation of the human DNA glycosylase NEIL2 and inhibition of its activity.
  Journal
Nucleic Acids Res 32:3033-9 (2004)
DOI:10.1093/nar/gkh632
  Sequence
[hsa:252969]

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