KEGG   ORTHOLOGY: K10592Help
Entry
K10592                      KO                                     

Name
HUWE1, MULE, ARF-BP1
Definition
E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
Pathway
ko04120  Ubiquitin mediated proteolysis
Disease
H00658  Syndromic X-linked mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K10592  HUWE1, MULE, ARF-BP1; E3 ubiquitin-protein ligase HUWE1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10592  HUWE1, MULE, ARF-BP1; E3 ubiquitin-protein ligase HUWE1
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     K10592  HUWE1, MULE, ARF-BP1; E3 ubiquitin-protein ligase HUWE1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  HECT type E3
   K10592  HUWE1, MULE, ARF-BP1; E3 ubiquitin-protein ligase HUWE1
BRITE hierarchy
Genes
HSA: 10075(HUWE1)
PTR: 465650(HUWE1)
PPS: 100972394(HUWE1)
GGO: 101135087(HUWE1)
PON: 100460369(HUWE1)
NLE: 100599649(HUWE1)
MCC: 700136(HUWE1)
MCF: 101925279(HUWE1)
CSAB: 103214877 103232019(HUWE1)
RRO: 104663369(HUWE1)
RBB: 108543716(HUWE1)
CJC: 100405596(HUWE1)
SBQ: 101046506(HUWE1)
MMU: 59026(Huwe1)
MUN: 110565890(Huwe1)
CGE: 100757403(Huwe1)
NGI: 103728650 103747333(Huwe1)
HGL: 101713610(Huwe1)
CCAN: 109695795(Huwe1)
OCU: 100342658(HUWE1)
TUP: 102493782(HUWE1)
CFA: 480931(HUWE1)
AML: 100483129(HUWE1)
UMR: 103675233(HUWE1)
ORO: 101369242(HUWE1)
FCA: 101091091(HUWE1)
PTG: 102958396(HUWE1)
AJU: 106985382(HUWE1)
BTA: 511826(HUWE1)
BOM: 102284096(HUWE1)
BIU: 109555074(HUWE1)
PHD: 102334464(HUWE1)
CHX: 102183583(HUWE1)
OAS: 101119368(HUWE1)
SSC: 100517442(HUWE1)
CFR: 102522120(HUWE1)
CDK: 105096697(HUWE1)
BACU: 103012524(HUWE1)
LVE: 103086224(HUWE1)
OOR: 101287454(HUWE1)
DLE: 111170787(HUWE1)
ECB: 100060375(HUWE1)
EPZ: 103544358 103566641(HUWE1)
EAI: 106822137(HUWE1)
MYB: 102240599(HUWE1)
MYD: 102754672(HUWE1)
MNA: 107538834(HUWE1)
HAI: 109396378(HUWE1)
RSS: 109438821(HUWE1)
PALE: 102882507(HUWE1)
LAV: 100676741(HUWE1)
TMU: 101360460
MDO: 100010537(HUWE1)
SHR: 100914679(HUWE1)
PCW: 110203530(HUWE1)
OAA: 100078721(HUWE1)
CJO: 107307736
APLA: 113841436(HUWE1)
LSR: 110480570(HUWE1)
SCAN: 103825067
GFR: 102042271(HUWE1)
PHI: 102110173(HUWE1)
FPG: 101922944(HUWE1)
FCH: 102059939(HUWE1)
CLV: 102086699 102092083(HUWE1)
AAM: 106497484 106497486(HUWE1)
ASN: 102368065(HUWE1)
CMY: 102936009
CPIC: 101930870(HUWE1)
ACS: 100563451(huwe1)
PVT: 110078623(HUWE1)
PBI: 103056552(HUWE1)
PMUR: 107289351(HUWE1)
GJA: 107120117(HUWE1)
XTR: 100126217(huwe1)
NPR: 108790458(HUWE1)
DRE: 559439(huwe1)
IPU: 108275910(huwe1)
PHYP: 113530462(huwe1)
AMEX: 103046443(huwe1)
EEE: 113590295(huwe1)
TRU: 101065803(huwe1)
LCO: 104932723(huwe1)
MZE: 101475677(huwe1)
OLA: 101170019(huwe1)
XMA: 102222690(huwe1)
PRET: 103467330(huwe1)
NFU: 107390860(huwe1)
KMR: 108244591(huwe1)
CSEM: 103384579(huwe1)
LCF: 108876401(huwe1)
SDU: 111219149(huwe1)
HCQ: 109520189(huwe1)
BPEC: 110164579(huwe1)
MALB: 109971616(huwe1)
SASA: 100380641(huwe1) 106567026
ELS: 105013560(huwe1)
PKI: 111855297(huwe1)
LCM: 102357002(HUWE1)
CIN: 100179586
SPU: 575742(huwe1)
APLC: 110973984
SKO: 100371483
DME: Dmel_CG8184(CG8184)
DER: 6550754
DPE: 6604638
DSI: Dsimw501_GD17230(Dsim_GD17230)
DWI: 6641095
DAZ: 108618013
DHE: 111596724
AME: 411961
BIM: 100742055
BTER: 100651406
SOC: 105204321
MPHA: 105828730
AEC: 105147676
ACEP: 105618859
PBAR: 105428011
HST: 105182813
DQU: 106747641
CFO: 105253642
LHU: 105676126
PGC: 109852223
OBO: 105276800
PCF: 106792106
NVI: 100123214(Huwe1)
MDL: 103569128
TCA: 657452(HUWE1)
DPA: 109533796
NVL: 108567076
FCD: 110858039
TUT: 107365454
CEL: CELE_Y67D8C.5(eel-1)
CBR: CBG03363(Cbr-eel-1)
BMY: Bm1_31595
TSP: Tsp_06790
MYI: 110442109
OBI: 106871200
LAK: 106174264
SHX: MS3_02566
EPA: 110241722
ADF: 107346651
PDAM: 113685976
SPIS: 111342278
ATH: AT1G55860(UPL1) AT1G70320(UPL2)
BOE: 106316847
LJA: Lj1g3v0180970.1(Lj1g3v0180970.1) Lj1g3v1526280.1(Lj1g3v1526280.1) Lj4g3v0217750.1(Lj4g3v0217750.1) Lj4g3v0217750.2(Lj4g3v0217750.2)
DOSA: Os09t0252700-01(Os09g0252700) Os09t0252800-01(Os09g0252800) Os12t0428600-01(Os12g0428600)
BDI: 100821130
ATS: 109768956(LOC109768956)
APRO: F751_0799
SCE: YDR457W(TOM1)
ERC: Ecym_4111
KMX: KLMA_40567(TOM1)
NCS: NCAS_0F01360(NCAS0F01360)
NDI: NDAI_0H01870(NDAI0H01870)
TPF: TPHA_0K00280(TPHA0K00280)
TBL: TBLA_0E02870(TBLA0E02870)
TDL: TDEL_0A04410(TDEL0A04410)
KAF: KAFR_0I01130(KAFR0I01130)
PIC: PICST_81688(TOM12)
CAL: CAALFM_C203180CA(TOM1)
SLB: AWJ20_3611(TOM1) AWJ20_3612(TOM1)
NCR: NCU08501
NTE: NEUTE1DRAFT146987(NEUTE1DRAFT_146987)
MGR: MGG_03252
SSCK: SPSK_08256
MAW: MAC_05649
MAJ: MAA_01855
CMT: CCM_05181
MBE: MBM_02648
ANI: AN1966.2
ANG: ANI_1_964184(An04g05870)
ABE: ARB_02273
TVE: TRV_04980
PTE: PTT_06702
SPO: SPAC19D5.04(ptr1)
CNE: CNI01260
CNB: CNBH1200
ABP: AGABI1DRAFT56206(AGABI1DRAFT_56206)
ABV: AGABI2DRAFT204611(AGABI2DRAFT_204611)
DFA: DFA_01821
EHI: EHI_104570(415.t00009)
PYO: PY17X_0704800(PY00959)
PCB: PCHAS_093350(PC301489.00.0)
SMIN: v1.2.002050.t1(symbB.v1.2.002050.t1) v1.2.002337.t1(symbB.v1.2.002337.t1)
SPAR: SPRG_03609
TCR: 508971.50
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Parsons JL, Tait PS, Finch D, Dianova II, Edelmann MJ, Khoronenkova SV, Kessler BM, Sharma RA, McKenna WG, Dianov GL
  Title
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.
  Journal
EMBO J 28:3207-15 (2009)
DOI:10.1038/emboj.2009.243
  Sequence
[hsa:10075]

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