KEGG ORTHOLOGY: K10596

ORTHOLOGY: K10596

Entry

K10596 KO

Name

UBE4A

Definition

ubiquitin conjugation factor E4 A [EC:2.3.2.27]

Pathway

ko04120

Ubiquitin mediated proteolysis

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K10596  UBE4A; ubiquitin conjugation factor E4 A
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10596  UBE4A; ubiquitin conjugation factor E4 A
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K10596  UBE4A; ubiquitin conjugation factor E4 A
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  U-box type E3
   K10596  UBE4A; ubiquitin conjugation factor E4 A

Genes

HSA:	9354(UBE4A)

PTR:	451586(UBE4A)

PPS:	100976919(UBE4A)

GGO:	101151381(UBE4A)

PON:	100189732(UBE4A)

NLE:	100582860(UBE4A)

MCC:	699836(UBE4A)

MCF:	102135339(UBE4A)

CSAB:

103248589(UBE4A)

CATY:

105582473(UBE4A)

RRO:	104665575(UBE4A)

RBB:	108536380(UBE4A)

TFN:	117081218(UBE4A)

CJC:	100405033(UBE4A)

SBQ:	101030487(UBE4A)

MMUR:

105876050(UBE4A)

MMU:	140630(Ube4a)

MCAL:

110301356(Ube4a)

MPAH:

110327792(Ube4a)

RNO:	315608(Ube4a)

MCOC:

116073933(Ube4a)

MUN:	110549095(Ube4a)

CGE:	100757349(Ube4a)

PLEU:

114691191(Ube4a)

NGI:	103748300(Ube4a)

HGL:	101711837(Ube4a)

CCAN:

109689974(Ube4a)

OCU:	100353223(UBE4A)

TUP:	102497795(UBE4A)

CFA:	479418(UBE4A)

VVP:	112920350(UBE4A)

AML:	100482208(UBE4A)

UMR:	103662334(UBE4A)

UAH:	113259998(UBE4A)

ORO:	101386558(UBE4A)

ELK:

111153725

MPUF:

101676881(UBE4A)

EJU:	114211287(UBE4A)

FCA:	101089796(UBE4A)

PTG:	102967583(UBE4A)

PPAD:

109278558(UBE4A)

AJU:	106966113(UBE4A)

BTA:	517544(UBE4A)

BOM:	102272004(UBE4A)

BIU:	109569531(UBE4A)

BBUB:

102416155(UBE4A)

CHX:	102191718(UBE4A)

OAS:	101123231(UBE4A)

SSC:	100513674(UBE4A)

CFR:	102518317(UBE4A)

CDK:	105090169(UBE4A)

BACU:

103004305(UBE4A)

LVE:	103069089(UBE4A)

OOR:	101279060(UBE4A)

DLE:	111166883(UBE4A)

PCAD:

102980334(UBE4A)

ECB:	100062986(UBE4A)

EPZ:	103546673(UBE4A)

EAI:	106840279(UBE4A)

MYB:	102239630(UBE4A)

MYD:	102754148(UBE4A)

MMYO:

118664235(UBE4A)

MNA:	107530800(UBE4A)

HAI:	109385287(UBE4A)

DRO:	112314185(UBE4A)

SHON:

118994759(UBE4A)

AJM:	119050764(UBE4A)

MMF:	118627532(UBE4A)

PALE:

102893988(UBE4A)

RAY:	107502261(UBE4A)

MJV:	108385111(UBE4A)

LAV:	100655010(UBE4A)

TMU:

101352481

MDO:	100025132(UBE4A)

SHR:	100918276(UBE4A)

PCW:	110207188(UBE4A)

OAA:	100090840(UBE4A)

GGA:	419758(UBE4A)

MGP:	100540968(UBE4A)

CJO:	107324136(UBE4A)

NMEL:

110387547(UBE4A)

APLA:

101801554(UBE4A)

TGU:	100219555(UBE4A)

LSR:	110470424(UBE4A)

SCAN:

103822785(UBE4A)

GFR:	102043864(UBE4A)

FAB:	101811483(UBE4A)

PHI:	102110358(UBE4A)

PMAJ:

107214458(UBE4A)

CCAE:

111939214(UBE4A)

CCW:	104692050(UBE4A)

ETL:	114056308(UBE4A)

FPG:	101912930(UBE4A)

FCH:	102055709(UBE4A)

CLV:	102090825(UBE4A)

EGZ:	104135367(UBE4A)

NNI:	104018512(UBE4A)

ACUN:

113488588(UBE4A)

PADL:

103916552(UBE4A)

AAM:	106485171(UBE4A)

ASN:	102381774(UBE4A)

AMJ:	102568388(UBE4A)

PSS:	102463884(UBE4A)

CMY:	102936220(UBE4A)

CPIC:

101940751(UBE4A)

ACS:	100560942(ube4a)

PVT:	110079187(UBE4A)

PBI:	103064429(UBE4A)

PMUR:

107284804(UBE4A)

TSR:	106540656(UBE4A)

PMUA:

114585240(UBE4A)

GJA:	107112549(UBE4A)

XLA:	108696459(ube4a.L) 414451(ube4a.S)

XTR:	100101757(ube4a)

NPR:	108795004(UBE4A)

DRE:	557121(ube4a)

SRX:	107718272 107743704

SANH:

107683820 107690452

SGH:	107585600 107601729(ube4a)

CCAR:

109103207 109103208

IPU:	108277663(ube4a)

PHYP:

113533006(ube4a)

AMEX:

103036005(ube4a)

EEE:	113579451(ube4a)

TRU:	101074716(ube4a)

TNG:	GSTEN00035708G001

LCO:	104936480(ube4a)

NCC:	104965387(ube4a)

MZE:	101468844(ube4a)

ONL:	100711218(ube4a)

OLA:	101166405(ube4a)

XMA:	102227336(ube4a)

XCO:	114133382(ube4a)

PRET:

103474565(ube4a)

CVG:	107088307(ube4a)

NFU:	107380360(ube4a)

KMR:	108246036(ube4a)

ALIM:

106533990(ube4a)

AOCE:

111579797(ube4a)

CSEM:

103378136(ube4a)

POV:	109630367(ube4a)

LCF:	108886383(ube4a)

SDU:	111228033(ube4a)

SLAL:

111650933(ube4a) 111652205

HCQ:	109529393(ube4a)

BPEC:

110154063(ube4a)

MALB:

109960200(ube4a)

SASA:

106612478(ube4a)

OTW:	112244676 112266727

SALP:

111949702 111960555(ube4a)

ELS:	105011720(ube4a)

SFM:	108936266(ube4a)

PKI:	111846263(ube4a)

LCM:	102349133(UBE4A)

CMK:	103180334(ube4a)

RTP:	109935608(ube4a)

CIN:

SPU:

APLC:

SKO:

DME:	Dmel_CG11070(CG11070)

DER:

6542188

DSE:

6611418

DSI:	Dsimw501_GD23424(Dsim_GD23424)

DYA:	Dyak_GE14044

DAN:

6497278

DSR:

110185593

DPO:	Dpse_GA10741

DPE:

6593550

DMN:

108163586

DWI:

6643680

DGR:	Dgri_GH13342

DMO:	Dmoj_GI17728

DAZ:

DNV:

DHE:

DVI:

MDE:

LCQ:

AGA:	AgaP_AGAP001681

AAG:

5563714

AALB:

109414933

CQU:	CpipJ_CPIJ001165

AME:

BIM:

BTER:

CCAL:

OBB:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

LHU:

PGC:

OBO:

PCF:

NVI:

CSOL:

MDL:

TCA:

DPA:

ATD:

NVL:

BMOR:

BMAN:

DPL:	KGM_206462

PMAC:

PRAP:

HAW:

TNL:

PXY:

API:

DNX:

AGS:

RMD:

BTAB:

CLEC:

PHU:	Phum_PHUM438080

ZNE:

110837225

DPX:	DAPPUDRAFT_56866

PVM:

113812422

ISC:	IscW_ISCW012014

DPTE:

113797286

CSCU:

111634891

PTEP:

107441297

LGI:	LOTGIDRAFT_210561

PCAN:

CRG:

MYI:

OBI:

LAK:

SMM:	Smp_030780

OVI:	T265_03542

EGL:

NVE:

EPA:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

HMG:

TAD:	TRIADDRAFT_60429

AQU:

100641431

PBE:	PBANKA_0704100

BMIC:

BMR1_03g03875

» show all

Reference

PMID:18069675

Authors

Sakiyama T, Fujita H, Tsubouchi H

Title

Autoantibodies against ubiquitination factor E4A (UBE4A) are associated with severity of Crohn's disease.

Journal

Inflamm Bowel Dis 14:310-7 (2008)
DOI:10.1002/ibd.20328

Sequence

[hsa:9354]

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (2306)   
   KEGG GENES (259)   
   KEGG MGENES (334)   
   RefGene (1710)   
   OC (3)   
Literature (1)   
   PubMed (1)   
All databases (2313)   

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