KEGG   ORTHOLOGY: K10648
Entry
K10648                      KO                                     
Symbol
TRIM5
Name
tripartite motif-containing protein 5 [EC:2.3.2.27]
Pathway
map03250  Viral life cycle - HIV-1
map05170  Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    K10648  TRIM5; tripartite motif-containing protein 5
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K10648  TRIM5; tripartite motif-containing protein 5
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10648  TRIM5; tripartite motif-containing protein 5
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K10648  TRIM5; tripartite motif-containing protein 5
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRIM/RBCC proteins
    K10648  TRIM5; tripartite motif-containing protein 5
Genes
HSA: 85363(TRIM5)
PTR: 503563(TRIM5)
PPS: 100984455(TRIM5)
GGO: 101133340(TRIM5)
PON: 100137088(TRIM5)
PPYG: 129008847(TRIM5)
NLE: 100589999(TRIM5)
HMH: 116476602(TRIM5)
SSYN: 129484507(TRIM5)
MCC: 574288(TRIM5)
MCF: 102135840(TRIM5)
MTHB: 126935065
MNI: 105468602(TRIM5)
CSAB: 103247881(TRIM5)
CATY: 105578889(TRIM5)
PANU: 100126714(TRIM5)
TGE: 112605771(TRIM5)
MLEU: 105533500(TRIM5)
RRO: 104663393(TRIM5)
RBB: 108538965(TRIM5)
TFN: 117081694(TRIM5)
PTEH: 111540945(TRIM5)
CANG: 105527301(TRIM5)
CJC: 100385852
SBQ: 101032043(TRIM5)
CIMI: 108288364(TRIM5)
ANAN: 105720336
CSYR: 103268948(TRIM5)
MMUR: 105883476
LCAT: 123642337(TRIM5)
PCOQ: 105818435(TRIM5)
MMU: 209387(Trim30d) 319236(Trim12c) 667823(Trim5)
RNO: 308906(Trim5) 499223(Trim30d)
HGL: 101716219(Trim5) 101721041
NCAR: 124958138
OCU: 100126072(TRIM5)
OPI: 101532545
UMR: 103680048
UAH: 113248236
UAR: 123782667
LLV: 125078130
MPUF: 101675922
MNP: 132023585
ORO: 105757834
MLX: 118004097
NSU: 110576227
FCA: 100302544(TRIM5)
PCOO: 112864903
PBG: 122483478
PVIV: 125176111
LRUF: 124504966
PTG: 102971923(TRIM34)
HHV: 120225598
BTA: 505265(TRIM5) 516599 616948 786870
BBUB: 102393893
SSC: 733579
CFR: 102506555
CBAI: 105076717
CDK: 116155384
VPC: 102533904
PKL: 118713480
PDIC: 114500409
PALE: 102888261
PGIG: 120590256
MJV: 108385131
TMU: 101353454
ETF: 101662635
 » show all
Reference
  Authors
Uchil PD, Quinlan BD, Chan WT, Luna JM, Mothes W
  Title
TRIM E3 ligases interfere with early and late stages of the retroviral life cycle.
  Journal
PLoS Pathog 4:e16 (2008)
DOI:10.1371/journal.ppat.0040016
  Sequence
[hsa:85363]
Reference
  Authors
Sawyer SL, Wu LI, Akey JM, Emerman M, Malik HS
  Title
High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans.
  Journal
Curr Biol 16:95-100 (2006)
DOI:10.1016/j.cub.2005.11.045
  Sequence
[hsa:85363]

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