KEGG ORTHOLOGY: K10707

ORTHOLOGY: K10707

Entry

K10707                      KO

Symbol

VAPB, ALS8

Name

vesicle-associated membrane protein-associated protein B

Pathway

map04979

Cholesterol metabolism

map05014

Amyotrophic lateral sclerosis

map05022

Pathways of neurodegeneration - multiple diseases

Disease

H00058

Amyotrophic lateral sclerosis (ALS)

H00455

Spinal muscular atrophy

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    K10707  VAPB, ALS8; vesicle-associated membrane protein-associated protein B
09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    K10707  VAPB, ALS8; vesicle-associated membrane protein-associated protein B
   05022 Pathways of neurodegeneration - multiple diseases
    K10707  VAPB, ALS8; vesicle-associated membrane protein-associated protein B
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K10707  VAPB, ALS8; vesicle-associated membrane protein-associated protein B
Membrane trafficking [BR:ko04131]
Autophagy
  Other autophagy associated proteins
   ER-mitochondria tethering complex
    K10707  VAPB, ALS8; vesicle-associated membrane protein-associated protein B

Other DBs

TC:	9.B.17.1.1 1.R.1.1.1

Genes

HSA:	9217(VAPB)

PTR:	469984(VAPB)

PPS:	100986802(VAPB)

GGO:	101127517(VAPB)

PON:	100439082(VAPB)

NLE:	100600539(VAPB)

HMH:	116463271 116463356 116811308

MCC:	695049(VAPB)

MTHB:

126929370 126954313

MNI:	105470587(VAPB)

CSAB:

103243598(VAPB)

CATY:

105585325(VAPB)

PANU:

101012391(VAPB)

TGE:	112632538(VAPB)

MLEU:

105548395

RRO:	104663791(VAPB)

RBB:	108515324(VAPB)

TFN:	117068988(VAPB)

PTEH:

111555642(VAPB)

CANG:

105507951(VAPB)

CJC:	100406329(VAPB)

SBQ:	101039391(VAPB)

CIMI:

108309943(VAPB)

CSYR:

103276572(VAPB)

MMUR:

105874525(VAPB)

LCAT:

123622897(VAPB)

PCOQ:

105820089(VAPB)

OGA:	100964669(VAPB)

MMU:	56491(Vapb)

MCAL:

110287007(Vapb)

MPAH:

110317767(Vapb)

RNO:	60431(Vapb)

MCOC:

116091489(Vapb)

ANU:	117694590 117703348(Vapb)

MUN:	110552834(Vapb)

CGE:	100768207(Vapb)

MAUA:

101832801(Vapb)

PROB:

127222881(Vapb)

PLEU:

114709830(Vapb)

MORG:

121440798(Vapb)

MFOT:

126508014

AAMP:

119814346(Vapb)

NGI:	103741569(Vapb)

HGL:	101711978(Vapb)

CPOC:

100736066(Vapb)

CCAN:

109690603(Vapb)

DORD:

105991618(Vapb)

DSP:	122124604(Vapb)

PLOP:

125353918(Vapb)

NCAR:

124976087

MMMA:

107137813(Vapb)

OCU:

100350714

OPI:	101524090(VAPB)

TUP:	102493591(VAPB)

GVR:	103582651 103599776(VAPB)

CFA:	477274(VAPB)

CLUD:

112674179(VAPB)

VVP:	112932164(VAPB)

VLG:	121477915(VAPB)

NPO:	129493552(VAPB)

AML:	100474439(VAPB)

UMR:	103670940(VAPB)

UAH:	113258765(VAPB)

UAR:	123799353(VAPB)

ELK:

111141408

LLV:

125108458

MPUF:

101691521(VAPB)

MNP:	132022058(VAPB)

MLK:	131808613(VAPB)

NVS:	122915938(VAPB)

ORO:	101362585(VAPB)

EJU:	114197924(VAPB)

ZCA:	113937292(VAPB)

MLX:	118024081(VAPB)

NSU:	110569886(VAPB)

LWW:	102745414(VAPB)

FCA:	101092172(VAPB)

PYU:	121019923(VAPB)

PCOO:

112868966(VAPB)

PBG:	122467224(VAPB)

PVIV:

125161840(VAPB)

LRUF:

124503108

PTG:	102965615(VAPB)

PPAD:

109253365(VAPB)

PUC:

125936455

AJU:

106988532

HHV:	120234868(VAPB)

BTA:	326580(VAPB)

BOM:	102275175(VAPB) 102282065

BIU:	109567297(VAPB) 109576737

BBUB:

102397700 102405900(VAPB)

BBIS:

104990024(VAPB)

CHX:	102176246(VAPB)

OAS:	101103170(VAPB)

BTAX:

128058185(VAPB)

ODA:	120869372(VAPB)

CCAD:

122448114(VAPB)

MBEZ:

129561588(VAPB)

SSC:	100144536(VAPB)

CFR:	102511320(VAPB)

CBAI:

105071963(VAPB)

CDK:	105098863(VAPB)

VPC:	102532884(VAPB)

BACU:

103006410(VAPB)

BMUS:

118881419(VAPB)

LVE:	103084006(VAPB)

OOR:	101285386(VAPB)

DLE:	111186656(VAPB)

PCAD:

102994108(VAPB)

PSIU:

116740247(VAPB)

NASI:

112403034(VAPB)

ECB:	100056253(VAPB)

EPZ:	103547040(VAPB)

EAI:	106824834(VAPB)

MYB:	102255142(VAPB)

MYD:	102757314(VAPB)

MMYO:

118662737(VAPB)

MLF:	102425881(VAPB)

PKL:	118708744(VAPB)

EFUS:

103285778(VAPB)

MNA:	107529419(VAPB)

DRO:	112303841(VAPB)

SHON:

118996535(VAPB)

AJM:

119055341

PDIC:

114506413(VAPB)

PHAS:

123815279(VAPB)

MMF:	118618771(VAPB)

PPAM:

129070599(VAPB)

HAI:	109380087(VAPB)

RFQ:	117015895(VAPB) 117022604

PALE:

102889020(VAPB)

PGIG:

120603876(VAPB)

PVP:	105296089(VAPB)

RAY:	107500046(VAPB)

MJV:	108408160(VAPB)

TOD:	119236877(VAPB)

SARA:

101536865 101543073(VAPB)

SETR:

126013325(VAPB)

LAV:	100668109(VAPB)

TMU:

101349168

ETF:	101656452(VAPB)

DNM:	101436209(VAPB)

MDO:	100021733(VAPB) 100028052

GAS:	123237152(VAPB)

SHR:	100931973(VAPB)

AFZ:

127548960

PCW:	110205148(VAPB)

OAA:	100080121(VAPB)

GGA:	419317(VAPB)

PCOC:

116225333(VAPB)

MGP:	100550972(VAPB)

CJO:	107323060(VAPB)

TPAI:

128081137(VAPB)

LMUT:

125701444(VAPB)

NMEL:

110408066(VAPB)

APLA:

101804793(VAPB)

ACYG:

106042141(VAPB)

CATA:

118248940(VAPB)

AFUL:

116495549(VAPB)

TGU:	100190400(VAPB)

LSR:	110483582(VAPB)

SCAN:

103818744(VAPB)

PMOA:

120507115(VAPB)

OTC:	121342980(VAPB)

PRUF:

121359449(VAPB)

GFR:	102042408(VAPB)

FAB:	101818870(VAPB)

OMA:	130261280(VAPB)

PHI:	102104949(VAPB)

PMAJ:

107213267(VAPB)

CCAE:

111938026(VAPB)

CCW:	104687804(VAPB)

CBRC:

103618029(VAPB)

ETL:	114056218(VAPB)

ZAB:	102061499(VAPB)

ACHL:

103800844(VAPB)

SVG:	106851694(VAPB)

MMEA:

130580554(VAPB)

HRT:	120760169(VAPB)

FPG:	101918588(VAPB)

FCH:	102051276(VAPB)

CLV:	102085309(VAPB)

EGZ:	104132137(VAPB)

NNI:	104013086(VAPB)

PCRI:

104032548(VAPB)

PLET:

104616727(VAPB)

EHS:	104507039(VAPB)

PCAO:

104048435(VAPB)

ACUN:

113487626(VAPB)

TALA:

104358230(VAPB)

PADL:

103919369(VAPB)

AFOR:

103895215(VAPB)

ACHC:

115338776(VAPB)

HALD:

104323612(VAPB)

HLE:	104833064(VAPB)

AGEN:

126045346

GCL:

127023146

CCRI:

104160161(VAPB)

CSTI:

104551533(VAPB)

CMAC:

104487054(VAPB)

MUI:	104538736(VAPB)

BREG:

104637080(VAPB)

FGA:	104079616(VAPB)

GSTE:

104254909(VAPB)

LDI:	104346866(VAPB)

MNB:	103781009(VAPB)

OHA:	104328867(VAPB)

NNT:	104408376(VAPB)

SHAB:

115615307(VAPB)

DPUB:

104302681(VAPB)

PGUU:

104459809(VAPB)

ACAR:

104522806(VAPB)

CPEA:

104389613(VAPB)

AVIT:

104273480(VAPB)

CVF:	104294046(VAPB)

RTD:	128916442(VAPB)

CUCA:

104067634(VAPB)

TEO:	104374955(VAPB)

BRHI:

104497004(VAPB)

AAM:	106492792(VAPB)

AROW:

112961004(VAPB)

NPD:	112949754(VAPB)

TGT:	104575633(VAPB)

DNE:	112978811 112981589 112983262 112991976 112992485 112993235(VAPB) 112994873 112995707

SCAM:

104141781(VAPB)

ASN:	102379274(VAPB)

AMJ:	106737265(VAPB)

CPOO:

109318794(VAPB)

GGN:	109292642(VAPB)

PSS:	102461080(VAPB)

CMY:	102934917(VAPB)

CCAY:

125622097(VAPB)

DCC:	119842021(VAPB)

CPIC:

101945410(VAPB)

TST:	117885637(VAPB)

CABI:

116826093(VAPB)

MRV:	120380937(VAPB)

ACS:	100556455(vapb)

ASAO:

132773098(VAPB)

PVT:	110091127(VAPB)

SUND:

121928361(VAPB)

PBI:

103066785

PMUR:

107302920(VAPB)

CTIG:

120298437(VAPB)

TSR:	106557153(VAPB)

PGUT:

117674876(VAPB)

APRI:

131195645(VAPB)

PTEX:

113434332(VAPB)

NSS:	113410385(VAPB)

VKO:	123036049(VAPB)

PMUA:

114599680(VAPB)

PRAF:

128416504(VAPB)

ZVI:	118088638(VAPB)

HCG:	128322598(VAPB)

GJA:	107120626(VAPB)

STOW:

125432799(VAPB)

EMC:	129330239(VAPB)

XLA:	108702191(vapbl.S) 495400(vapb.S)

XTR:	394500(vapb)

NPR:	108802926(VAPB)

RTEM:

120919442(VAPB)

BBUF:

121004307(VAPB)

BGAR:

122942350(VAPB)

MUO:	115476958(VAPB)

GSH:	117345710(VAPB)

DRE:	323628(vapb)

SRX:	107708147 107729754

SANH:

107666099 107685803

SGH:	107554163 107596792(vapb)

CCAR:

109082397 109091591(vapb)

CAUA:

113050272 113105105

CGIB:

127959622 128015931

PTET:

122327306 122346805(vapb)

LROH:

127166469(vapb)

OMC:	131542607(vapb)

PPRM:

120493696(vapb)

RKG:	130104011(vapb)

MAMB:

125273555(vapb)

CIDE:

127514923

MASI:

127445964 127449202

TROS:

130557110(vapb)

TDW:	130424908(vapb)

MANU:

129450450(vapb)

IPU:

124628749

IFU:	128615516(vapb)

PHYP:

113545976(vapb)

SMEO:

124390421(vapb)

TFD:	113642924(vapb)

TVC:	132844732(vapb)

AMEX:

103028744(vapb)

CMAO:

118808629(vapb)

EEE:	113577858(vapb)

CHAR:

105910081(vapb)

TRU:	101062942 101078863

TFS:	130524852 130530575

TNG:	GSTEN00022572G001 GSTEN00033855G001

LCO:	104928381 104936174

NCC:	104943624 104966803(vapb)

TBEN:

117489570(vapb) 117494440

CGOB:

115008555 115010749

PGEO:

117446562(vapb) 117449269

GACU:

117539571 117541889

EMAC:

134863488 134883117

ELY:	117256996 117258624

EFO:	125889027 125891961

PLEP:

121946600 121956728(vapb)

SLUC:

116040687 116051427(vapb)

ECRA:

117943673(vapb) 117948266

ESP:	116688271 116693016(vapb)

PFLV:

114554635 114558380(vapb)

GAT:	120829644 120835132

PPUG:

119222358 119230105

AFB:	129100342 129105574(vapb)

CLUM:

117730922(vapb) 117733592

PSWI:

130199763 130208620

MSAM:

119886022 119905694

SCHU:

122882722 122884900

CUD:	121507142 121517257

ALAT:

119021500 119022185

MZE:	101477347 101481364

ONL:	100690067(vapb) 100711919

OAU:	116318965 116319424

OLA:	101163410 101174096

OML:	112145135(vapb) 112158806

CSAI:

133448362(vapb) 133457366

XMA:	102220519 102227542

XCO:	114135605 114149263

XHE:	116710546 116725197

PRET:

103464667 103468029

PFOR:

103134561 103156041

PLAI:

106952904(vapb) 106960241

PMEI:

106920206 106929015

GAF:	122833952 122840022(vapb)

PPRL:

129372433 129372854

CVG:	107086688(vapb) 107101132

CTUL:

119788646 119789235

GMU:	124857380 124874415

NFU:	107385402 107390602(vapb)

KMR:	108231687 108236820

ALIM:

106511142 106511321

NWH:	119411879 119417684

AOCE:

111577710 111579187

MCEP:

125006567(vapB) 125014446

CSEM:

103384510(vapb) 103386742

POV:	109630872 109635584

SSEN:

122768246 122777666

HHIP:

117761334 117764557

HSP:	118104489 118110838

SMAU:

118309497(vapb) 118316833

LCF:	108873560(vapb) 108891677

SDU:	111219133 111233565

SLAL:

111660678 111670679

XGL:	120783371 120804119

HCQ:	109507376 109517766

SSCV:

125977387 125988003

SBIA:

133507804(vapb)

PEE:	133399621 133409098

PTAO:

133474630 133484224

BPEC:

110155828 110174719

MALB:

109970526 109970707(vapb)

BSPL:

114855878(vapb) 114858939

SJO:	128355699 128357128

SASA:

106565072(VAPB) 106566691 106571963(VAPB) 106583688

STRU:

115150077 115166206 115168327(vapb) 115208386

OTW:	112215818 112222133 112255050 112267023

OMY:	110492343 110493884 110528568 110532056

OGO:	124003462 124026016 124031748 124045729

ONE:	115102161 115131940 115142857 115144256

OKI:	109869804(vapb) 109891238 109891657 109907815

OKE:	118359689 118361341 118388923 118400619

SALP:

111961637 111966256 111976688

SNH:	120026625 120059470 120061289 120065470

CCLU:

121538122 121545468 121575594 121577959

ELS:	105016682 105026336(vapb)

SFM:	108928435(vapb) 108930464

PKI:	111835314(vapb) 111844708

AANG:

118208476 118211464(vapb)

LOC:	102694380(vapb)

PSPA:

121298504 121319446(vapb)

ARUT:

117424702 117433147

PSEX:

120514229(vapb)

LCM:	102358753(VAPB)

CMK:	103173009(vapb)

CPLA:

122559936(vapb)

HOC:	132822684(vapb)

LERI:

129707204(vapb)

CIN:

100181593

SCLV:

120332383 120332415

AJC:

117115002

DSI:	Dsimw501_GD16666(Dsim_GD16666) Dsimw501_GD22847(Dsim_GD22847)

DYA:	Dyak_GE15138 Dyak_GE16322

DMN:	108161476 108165430

DWI:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

CQU:	CpipJ_CPIJ019990

MGEN:

CGIG:

AGIF:

CINS:

VCAN:

TCA:

DPA:

AGRG:

ATD:

CSET:

AGB:

PPYR:

OTU:

MSEX:

DPL:	KGM_206149

MCIX:

CCRN:

CLEC:

NLU:

HVI:

MQU:

CSEC:

SGRE:

HAME:

PTRU:

LSM:

TCF:

PPOI:

119098656 119099053 119099368 119106256

DSV:

RSAN:

RMP:

VDE:

VJA:

CSCU:

111624979 111625035 111630095 111630097 111630109

PTEP:

107442199

UDV:	129225605 129229204

SDM:	118179797 118185213 118192845

CEL:	CELE_F33D11.11(vpr-1)

CBR:	CBG_04017(Cbr-vpr-1)

CRQ:	GCK72_001033 GCK72_011611 GCK72_011612

TSP:

Tsp_07972

HRO:	HELRODRAFT_188273

PDAM:

SPIS:

HSY:

CPV:

CHO:	Chro.60303

TGO:	TGME49_318160

PTM:	GSPATT00035261001 GSPATT00036789001

EHX:	EMIHUDRAFT_204351

GTT:	GUITHDRAFT_155842

» show all

Reference

PMID:22131369

Authors

De Vos KJ, Morotz GM, Stoica R, Tudor EL, Lau KF, Ackerley S, Warley A, Shaw CE, Miller CC

Title

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis.

Journal

Hum Mol Genet 21:1299-311 (2012)
DOI:10.1093/hmg/ddr559

Sequence

[hsa:9217]

Reference

PMID:9920726

Authors

Nishimura Y, Hayashi M, Inada H, Tanaka T

Title

Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins.

Journal

Biochem Biophys Res Commun 254:21-6 (1999)
DOI:10.1006/bbrc.1998.9876

Sequence

[hsa:9217]

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Gene (1032)   
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