KEGG   ORTHOLOGY: K10772Help
Entry
K10772                      KO                                     

Name
APEX2
Definition
AP endonuclease 2 [EC:4.2.99.18]
Pathway
ko03410  Base excision repair
Module
M00296  BER complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    K10772  APEX2; AP endonuclease 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K10772  APEX2; AP endonuclease 2
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Repair system
    M00296  BER complex
     K10772  APEX2; AP endonuclease 2
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.99  Other carbon-oxygen lyases
    4.2.99.18  DNA-(apurinic or apyrimidinic site) lyase
     K10772  APEX2; AP endonuclease 2
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    AP endonucleases
     K10772  APEX2; AP endonuclease 2
BRITE hierarchy
Other DBs
GO: 0003906
Genes
HSA: 27301(APEX2)
PTR: 473625(APEX2)
PPS: 100975705(APEX2)
GGO: 101142413(APEX2)
PON: 100434759(APEX2)
NLE: 100594886(APEX2)
MCC: 702084(APEX2)
MCF: 102140119(APEX2)
CSAB: 103232031(APEX2)
RRO: 104657179(APEX2)
RBB: 108540601(APEX2)
CJC: 100410557(APEX2)
SBQ: 101033991(APEX2)
MMU: 77622(Apex2)
RNO: 289662(Apex2l1) 317628(Apex2)
CGE: 100753797(Apex2) 100772896
NGI: 103738666(Apex2)
HGL: 101701150(Apex2)
CCAN: 109700224(Apex2)
OCU: 100350593(APEX2)
TUP: 102493772(APEX2)
CFA: 100855516(APEX2)
AML: 100484412(APEX2)
UMR: 103682096(APEX2)
ORO: 101376591(APEX2)
FCA: 101095317(APEX2)
PTG: 102969410(APEX2)
AJU: 106986449(APEX2)
BTA: 511790(APEX2)
BOM: 102265511(APEX2)
BIU: 109555447(APEX2)
PHD: 102318512(APEX2)
CHX: 102174734(APEX2)
OAS: 101116123(APEX2)
SSC: 100519003(APEX2)
CFR: 102504985(APEX2)
CDK: 105103538(APEX2)
BACU: 103013850(APEX2)
LVE: 103072593(APEX2)
OOR: 101283465(APEX2)
ECB: 100062550(APEX2)
EPZ: 103541965(APEX2) 103546111
EAI: 106834246(APEX2)
MYB: 102245079(APEX2)
MYD: 102752277(APEX2) 102766559
HAI: 109396961(APEX2)
RSS: 109438838(APEX2)
PALE: 102898078(APEX2)
LAV: 100654358(APEX2)
TMU: 101341791
MDO: 100012903(APEX2)
SHR: 100927463(APEX2)
OAA: 100079599(APEX2)
ASN: 102368546(APEX2)
AMJ: 102563647(APEX2)
CMY: 102936240(APEX2)
CPIC: 101953753(APEX2)
ACS: 100567501(apex2)
PVT: 110078641(APEX2)
PBI: 103059473(APEX2)
GJA: 107121340(APEX2)
XLA: 446614(apex2.L)
XTR: 448512(apex2)
NPR: 108797520(APEX2)
DRE: 393115(apex2)
SRX: 107731139(apex2) 107745771
CCAR: 109061994 109065663(apex2)
IPU: 108265419(apex2)
AMEX: 103032472(apex2)
TRU: 101076869(apex2)
LCO: 104924685(apex2)
NCC: 104951560(apex2)
MZE: 101465054(apex2)
XMA: 102228428(apex2)
NFU: 107390522(apex2)
CSEM: 103385365(apex2)
LCF: 108882165(apex2)
BPEC: 110164670(apex2)
SASA: 106572385(apex2)
ELS: 105022379(apex2)
SFM: 108918403(apex2)
LCM: 102352181(APEX2)
CMK: 103188060(apex2)
SPU: 579199
APLC: 110974927
SKO: 100369245
PXY: 105397721
ZNE: 110834938
FCD: 110862814
TUT: 107364220
TSP: Tsp_03481
CRG: 105342546
MYI: 110460977
OBI: 106875990
SHX: MS3_04148
EPA: 110250015
ADF: 107345852
HMG: 100210591
AQU: 100633380
ATH: AT4G36050
CRB: 17879523
BRP: 103870940
BOE: 106292286
THJ: 104807495
CPAP: 110822146
CIT: 102619750
TCC: 18610767
GRA: 105803710
DZI: 111293483
EGR: 104419655
GMX: 100781120
VRA: 106769070
VAR: 108323322
CCAJ: 109792342
CAM: 101493577
LJA: Lj4g3v1037650.1(Lj4g3v1037650.1) Lj4g3v1037650.2(Lj4g3v1037650.2)
ADU: 107476704
AIP: 107624490
LANG: 109350171
FVE: 101299414
PPER: 18771901
PMUM: 103340209
PAVI: 110758015
MDM: 103456392
PXB: 103967814
ZJU: 107424365
CSV: 101222374
CMO: 103485130
MCHA: 111005866
CMAX: 111497328
CMOS: 111433494
CPEP: 111780976
RCU: 8281334
JCU: 105629025
HBR: 110641155
POP: 18101085
JRE: 108997720
VVI: 100264349
SLY: 101246406
SPEN: 107012604
SOT: 102587879
CANN: 107868185
NSY: 104216114
NTO: 104087768
INI: 109167702
SIND: 105178166
OEU: 111365382
HAN: 110878477
LSV: 111881139
DCR: 108196643
BVG: 104895192
SOE: 110803627
NNU: 104605552
OSA: 4347697
DOSA: Os09t0536000-01(Os09g0536000)
OBR: 102700368
BDI: 100830878
SBI: 8070906
ZMA: 103633096
SITA: 101776015
PDA: 103706340
EGU: 105055065
MUS: 103970608
DCT: 110097589
AOF: 109851358
ATR: 18441633
PPP: 112294403
APRO: F751_5145
SCE: YBL019W(APN2)
ERC: Ecym_6193
KMX: KLMA_20038(APN2)
NCS: NCAS_0B05590(NCAS0B05590)
NDI: NDAI_0B02930(NDAI0B02930)
TPF: TPHA_0H00210(TPHA0H00210)
TBL: TBLA_0A08780(TBLA0A08780)
TDL: TDEL_0B04460(TDEL0B04460)
KAF: KAFR_0C02810(KAFR0C02810)
PIC: PICST_28317(APN2)
CAL: CAALFM_C110650WA(APN2)
CAUR: QG37_06281
SLB: AWJ20_441(APN2)
NCR: NCU01961
NTE: NEUTE1DRAFT149501(NEUTE1DRAFT_149501)
MGR: MGG_02980
MAW: MAC_05349
MAJ: MAA_03720
CMT: CCM_06524
BFU: BCIN_01g02130(Bcapn2)
MBE: MBM_00652
ANI: AN4736.2
ANG: ANI_1_1326094(An11g10190)
ABE: ARB_07318
TVE: TRV_02049
PTE: PTT_09967
ZTR: MYCGRDRAFT_88442(APN2)
SPO: SPBC3D6.10(apn2)
CNE: CNI04070
CNB: CNBH3880
ABP: AGABI1DRAFT70906(AGABI1DRAFT_70906)
ABV: AGABI2DRAFT179106(AGABI2DRAFT_179106)
MGL: MGL_3205
NGD: NGA_2014810(APEX2) NGA_2014820(APEX2)
SPAR: SPRG_02459
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Burkovics P, Hajdu I, Szukacsov V, Unk I, Haracska L
  Title
Role of PCNA-dependent stimulation of 3'-phosphodiesterase and 3'-5' exonuclease activities of human Ape2 in repair of oxidative DNA damage.
  Journal
Nucleic Acids Res 37:4247-55 (2009)
DOI:10.1093/nar/gkp357
  Sequence
[hsa:27301]
Reference
  Authors
Fraser JL, Neill E, Davey S
  Title
Fission yeast Uve1 and Apn2 function in distinct oxidative damage repair pathways in vivo.
  Journal
DNA Repair (Amst) 2:1253-67 (2003)
DOI:10.1016/j.dnarep.2003.08.005
  Sequence

DBGET integrated database retrieval system