KEGG   ORTHOLOGY: K10790Help
Entry
K10790                      KO                                     

Name
TREX1
Definition
three prime repair exonuclease 1 [EC:3.1.11.2]
Pathway
ko04623  Cytosolic DNA-sensing pathway
Disease
H00290  Aicardi-Goutieres syndrome (AGS)
H00291  Familial chilblain lupus (FCL)
H01000  Retinal vasculopathy with cerebral leukodystrophy (RVCL)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04623 Cytosolic DNA-sensing pathway
    K10790  TREX1; three prime repair exonuclease 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.11  Exodeoxyribonucleases producing 5'-phosphomonoesters
    3.1.11.2  exodeoxyribonuclease III
     K10790  TREX1; three prime repair exonuclease 1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  Other factors with a suspected DNA repair function
   Nucleases
    K10790  TREX1; three prime repair exonuclease 1
BRITE hierarchy
Other DBs
GO: 0008296
Genes
HSA: 11277(TREX1)
PTR: 742742(TREX1)
PPS: 100982424(TREX1)
GGO: 101148143(TREX1)
PON: 100452811(TREX1)
NLE: 100591582(TREX1)
MCC: 100429168(TREX1)
MCF: 102145869(TREX1)
CSAB: 103227588(TREX1)
RRO: 104667839(TREX1)
RBB: 108527023(TREX1)
CJC: 100385398(TREX1)
SBQ: 101042042(TREX1)
MMU: 22040(Trex1)
RNO: 100049583(Trex1)
CGE: 100761854(Trex1)
NGI: 103750224(Trex1)
HGL: 101715376(Trex1)
CCAN: 109695273(Trex1)
OCU: 100355546(TREX1)
TUP: 102468212(TREX1)
CFA: 102155466(TREX1)
AML: 100476000(TREX1)
UMR: 103674850(TREX1)
ORO: 101372274(TREX1)
FCA: 101098935(TREX1)
PTG: 102964735(TREX1)
AJU: 106979179(TREX1)
BTA: 282099(TREX1)
BOM: 102271118(TREX1)
BIU: 109576261(TREX1)
CHX: 102189528(TREX1)
OAS: 101119766(TREX1)
SSC: 100155669(TREX1)
CFR: 102522505(TREX1)
CDK: 105087958(TREX1)
BACU: 103013392(TREX1)
LVE: 103087946(TREX1)
OOR: 101285141(TREX1)
ECB: 100063767(TREX1)
EPZ: 103556025(TREX1)
EAI: 106821772(TREX1)
MYD: 102761907(TREX1)
HAI: 109377922(TREX1)
RSS: 109443496(TREX1)
PALE: 102883126(TREX1)
LAV: 100675657(TREX1)
TMU: 101348902
MDO: 100023478(TREX1)
SHR: 105749561(TREX1)
OAA: 100078153(TREX1)
AAM: 106486659(TREX1)
ACS: 100561159(trex1)
PVT: 110080645
GJA: 107115530(TREX1)
CIN: 104266336
SPU: 755651
DSI: Dsimw501_GD23197(Dsim_GD23197)
MDE: 101891133
PBAR: 105427485
TCA: 657958
BMOR: 101738032
PMAC: 106715110
ZNE: 110828923
CRG: 105343831
OBI: 106879354
SHX: MS3_06950
EPA: 110242758
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Mazur DJ, Perrino FW
  Title
Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases.
  Journal
J Biol Chem 274:19655-60 (1999)
DOI:10.1074/jbc.274.28.19655
  Sequence
[hsa:11277] [mmu:22040]

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