KEGG   ORTHOLOGY: K10849Help
Entry
K10849                      KO                                     

Name
ERCC1
Definition
DNA excision repair protein ERCC-1
Pathway
ko01524  Platinum drug resistance
ko03420  Nucleotide excision repair
ko03460  Fanconi anemia pathway
Disease
H00403  Disorders of nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03420 Nucleotide excision repair
    K10849  ERCC1; DNA excision repair protein ERCC-1
   03460 Fanconi anemia pathway
    K10849  ERCC1; DNA excision repair protein ERCC-1
 09160 Human Diseases
  09168 Drug resistance
   01524 Platinum drug resistance
    K10849  ERCC1; DNA excision repair protein ERCC-1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K10849  ERCC1; DNA excision repair protein ERCC-1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    Other NER factors
     K10849  ERCC1; DNA excision repair protein ERCC-1
BRITE hierarchy
Genes
HSA: 2067(ERCC1)
PTR: 450179(ERCC1)
PPS: 100988695(ERCC1)
GGO: 101126179(ERCC1)
PON: 100458035(ERCC1)
NLE: 100596810(ERCC1)
MCC: 574267(ERCC1)
MCF: 102117117(ERCC1)
CSAB: 103234864(ERCC1)
RRO: 104673444(ERCC1)
RBB: 108531042(ERCC1)
CJC: 100399191(ERCC1)
SBQ: 101047754(ERCC1)
MMU: 13870(Ercc1)
RNO: 292673(Ercc1)
CGE: 100689377(Ercc1)
NGI: 103749192(Ercc1)
HGL: 101699727(Ercc1)
CCAN: 109692373(Ercc1)
OCU: 100348713(ERCC1)
TUP: 102482297(ERCC1)
CFA: 612282(ERCC1)
AML: 100474654(ERCC1)
UMR: 103657053(ERCC1)
ORO: 101379426(ERCC1)
FCA: 101095455(ERCC1)
PTG: 102972717(ERCC1)
AJU: 106973646(ERCC1)
BTA: 615637(ERCC1)
BOM: 102279664(ERCC1)
BIU: 109572638(ERCC1)
PHD: 102335817(ERCC1)
CHX: 102170905(ERCC1)
OAS: 101116856(ERCC1)
SSC: 100286808(ERCC1)
CFR: 102523113(ERCC1)
CDK: 105095452(ERCC1)
BACU: 103010233(ERCC1)
LVE: 103075003(ERCC1)
OOR: 101287052(ERCC1)
ECB: 100065660(ERCC1)
EPZ: 103567007(ERCC1)
EAI: 106843738(ERCC1)
MYB: 102255674(ERCC1)
MYD: 102753294(ERCC1)
HAI: 109374734(ERCC1)
RSS: 109459926(ERCC1)
PALE: 102891932(ERCC1)
LAV: 100673932(ERCC1)
TMU: 101354771
MDO: 100011871(ERCC1)
SHR: 100929831(ERCC1)
OAA: 100087730(ERCC1)
PHI: 102105527(ERCC1)
AAM: 106484842(ERCC1)
ASN: 102378728(ERCC1)
AMJ: 102571565(ERCC1)
PSS: 102456222(ERCC1)
CMY: 102938503
CPIC: 101953433(ERCC1)
ACS: 100565865(ercc1)
PVT: 110075720(ERCC1)
PBI: 103067428(ERCC1)
GJA: 107106823(ERCC1)
XLA: 380190(ercc1.L)
XTR: 100135224(ercc1)
NPR: 108801263(ERCC1)
DRE: 100001425(ercc1)
SRX: 107719824(ercc1) 107731738
SANH: 107659901(ercc1)
SGH: 107570013 107595841(ercc1)
IPU: 108266085(ercc1)
AMEX: 103040846(ercc1)
TRU: 101064749(ercc1)
LCO: 104928744(ercc1) 109140366
NCC: 104963312(ercc1)
MZE: 101468887(ercc1)
OLA: 101168825(ercc1)
XMA: 102221206(ercc1)
PRET: 103461642(ercc1)
NFU: 107390137(ercc1)
CSEM: 103392048(ercc1)
LCF: 108880456(ercc1)
HCQ: 109523416(ercc1)
BPEC: 110161902
SASA: 100286713(ercc1)
ELS: 105029812(ercc1)
SFM: 108937446(ercc1)
LCM: 102352480(ERCC1)
CIN: 101242850
SPU: 586875
APLC: 110986047
SKO: 100367158
DME: Dmel_CG10215(Ercc1)
DSI: Dsimw501_GD11080(Dsim_GD11080)
MDE: 101888986
AAG: 5570104
AME: 551316(Ercc1)
BIM: 100746091
BTER: 100645693
SOC: 105208184
AEC: 105147231
ACEP: 105619747
PBAR: 105422296
HST: 105182820
CFO: 105254088
LHU: 105673378
PGC: 109855141
NVI: 100120321
TCA: 658919
DPA: 109544693
NVL: 108565395
BMOR: 101743797
PMAC: 106720591
PRAP: 110995179
API: 100162911
DNX: 107170018
ZNE: 110837252
FCD: 110863375
TUT: 107364778
CEL: CELE_F10G8.7(ercc-1)
CBR: CBG03787
TSP: Tsp_01641
MYI: 110461691
OBI: 106871903
LAK: 106174949
SHX: MS3_09191
ADF: 107332046
HMG: 101236335
AQU: 109593734
ATH: AT3G05210(ERCC1)
CRB: 17893748
BRP: 103870844
BNA: 106453031
BOE: 106292652
THJ: 104820089
CPAP: 110812430
TCC: 18600419
GRA: 105782865
DZI: 111297121
EGR: 104415536
GMX: 100777022
VRA: 106770909
VAR: 108346112
CCAJ: 109790266
CAM: 101508212
LJA: Lj0g3v0154809.1(Lj0g3v0154809.1)
ADU: 107465429
AIP: 107618066
LANG: 109335970
FVE: 101302568
PPER: 18772181
PMUM: 103344672
PAVI: 110759682
MDM: 103427694
PXB: 103928320
ZJU: 107411977
CSV: 101213096
CMO: 103501314
MCHA: 111026050
CMAX: 111467887
CMOS: 111462101
CPEP: 111780129
RCU: 8285528
JCU: 105647576
HBR: 110658037
POP: 18098811
VVI: 100244316
SLY: 101261110
SPEN: 107012627
SOT: 102603702
CANN: 107862305
NSY: 104242551
NTO: 104099494
INI: 109162796
SIND: 105171920
HAN: 110910977
LSV: 111918914
DCR: 108200801
BVG: 104907763
SOE: 110786211
NNU: 104594017
OSA: 4349131
DOSA: Os10t0518900-01(Os10g0518900)
OBR: 102717007
BDI: 100833808
ATS: 109778025(LOC109778025)
SBI: 8065686
ZMA: 100192592
SITA: 101755670
PDA: 103717364
EGU: 105043469
MUS: 103970985
DCT: 110103353
AOF: 109839562
ATR: 18438880
PPP: 112283880
OLU: OSTLU_119485(ercC)
MIS: MICPUN_107323(ERCC)
SCE: YML095C(RAD10)
ERC: Ecym_8154
KMX: KLMA_20664(RAD10)
NCS: NCAS_0C00180(NCAS0C00180)
NDI: NDAI_0K00190(NDAI0K00190)
TPF: TPHA_0I00120(TPHA0I00120)
TBL: TBLA_0C06310(TBLA0C06310)
TDL: TDEL_0B00430(TDEL0B00430)
KAF: KAFR_0A03000(KAFR0A03000)
PIC: PICST_28360(RAD10)
CAL: CAALFM_C105820CA(RAD10)
CAUR: QG37_03764
SLB: AWJ20_3782(RAD10)
NCR: NCU07066(mus-44)
NTE: NEUTE1DRAFT68281(NEUTE1DRAFT_68281)
MGR: MGG_14640
MAW: MAC_03408
MAJ: MAA_02005
CMT: CCM_00322
MBE: MBM_06048
ANI: AN4331.2
ANG: ANI_1_1544184(An04g00580)
ABE: ARB_02680
TVE: TRV_05441
SPO: SPBC4F6.15c(swi10)
CNE: CNF01110
CNB: CNBF3600
ABP: AGABI1DRAFT71740(AGABI1DRAFT_71740)
ABV: AGABI2DRAFT204704(AGABI2DRAFT_204704)
MGL: MGL_1678
DDI: DDB_G0267682(ercc1)
DFA: DFA_11925(ercc1)
EHI: EHI_126160(117.t00040)
PYO: PY17X_0301700(PY06905)
PCB: PCHAS_030340(PC000859.01.0)
TAN: TA16745
TPV: TP01_0997
BBO: BBOV_III011710(17.m10652)
CPV: cgd6_2610
SMIN: v1.2.018882.t1(symbB.v1.2.018882.t1)
FCY: FRACYDRAFT_181618(ERCC1)
SPAR: SPRG_03981
GTT: GUITHDRAFT_69282(ERCC1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2420469
  Authors
van Duin M, de Wit J, Odijk H, Westerveld A, Yasui A, Koken MH, Hoeijmakers JH, Bootsma D
  Title
Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10.
  Journal
Cell 44:913-23 (1986)
DOI:10.1016/0092-8674(86)90014-0
  Sequence
[hsa:2067]
Reference
PMID:8479526
  Authors
Tomkinson AE, Bardwell AJ, Bardwell L, Tappe NJ, Friedberg EC
  Title
Yeast DNA repair and recombination proteins Rad1 and Rad10 constitute a single-stranded-DNA endonuclease.
  Journal
Nature 362:860-2 (1993)
DOI:10.1038/362860a0
  Sequence
[sce:YML095C]
Reference
  Authors
Friboulet L, Postel-Vinay S, Sourisseau T, Adam J, Stoclin A, Ponsonnailles F, Dorvault N, Commo F, Saulnier P, Salome-Desmoulez S, Pottier G, Andre F, Kroemer G, Soria JC, Olaussen KA
  Title
ERCC1 function in nuclear excision and interstrand crosslink repair pathways is mediated exclusively by the ERCC1-202 isoform.
  Journal
Cell Cycle 12:3298-306 (2013)
DOI:10.4161/cc.26309
  Sequence
[hsa:2067]

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