KEGG ORTHOLOGY: K10860

ORTHOLOGY: K10860

Entry

K10860                      KO

Symbol

ALKBH3, DEPC1

Name

mRNA N1-methyladenine demethylase [EC:1.14.11.54]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K10860  ALKBH3, DEPC1; mRNA N1-methyladenine demethylase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.54  mRNA N1-methyladenine demethylase
     K10860  ALKBH3, DEPC1; mRNA N1-methyladenine demethylase
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  SSBR (single strand breaks repair)
   Direct repair
    K10860  ALKBH3, DEPC1; mRNA N1-methyladenine demethylase

Other DBs

GO:	0043734 0051747

Genes

HSA:	221120(ALKBH3)

PTR:	741336(ALKBH3)

PPS:	100973808(ALKBH3)

GGO:	101128171(ALKBH3)

PON:	100171823(ALKBH3)

PPYG:

129007839(ALKBH3)

NLE:	100602324(ALKBH3)

HMH:	116476330(ALKBH3)

SSYN:

129484209(ALKBH3)

MCC:	715921(ALKBH3)

MCF:	101925097(ALKBH3)

MTHB:

126935986

MNI:	105471609(ALKBH3)

CSAB:

103237116(ALKBH3)

CATY:

105586836(ALKBH3)

PANU:

101021086(ALKBH3)

TGE:	112607176(ALKBH3)

MLEU:

105554773(ALKBH3)

RRO:	104673889(ALKBH3)

RBB:	108519277(ALKBH3)

TFN:	117079980(ALKBH3)

PTEH:

111544937(ALKBH3)

CANG:

105527083(ALKBH3)

CJC:	100399955(ALKBH3)

SBQ:	101038261(ALKBH3)

CIMI:

108304911(ALKBH3)

ANAN:

105717302(ALKBH3)

CSYR:

103272130(ALKBH3)

MMUR:

105885533(ALKBH3)

LCAT:

123642614(ALKBH3)

PCOQ:

105819147(ALKBH3)

OGA:	100948961(ALKBH3)

MMU:	69113(Alkbh3)

MCAL:

110284895(Alkbh3)

MPAH:

110318986(Alkbh3)

RNO:	362169(Alkbh3)

MCOC:

116090520(Alkbh3)

ANU:	117704196(Alkbh3)

ASYL:

127685652(Alkbh3)

MUN:	110540590(Alkbh3)

CGE:	100774403(Alkbh3)

MAUA:

101841578(Alkbh3)

PROB:

127222210(Alkbh3)

PLEU:

114699732(Alkbh3)

MORG:

121440554(Alkbh3)

MFOT:

126504682

AAMP:

119814197(Alkbh3)

NGI:	103746670(Alkbh3)

HGL:	101716978(Alkbh3)

CPOC:

100721589(Alkbh3)

CCAN:

109697777(Alkbh3)

DORD:

105996071(Alkbh3)

DSP:	122100744(Alkbh3)

PLOP:

125361836(Alkbh3)

NCAR:

124960109

MMMA:

107135772(Alkbh3)

ITI:	101965355(Alkbh3)

OCU:

100342939

OPI:	101520863 101530194(ALKBH3)

TUP:	102495653(ALKBH3)

GVR:	103602945(ALKBH3)

CFA:	475938(ALKBH3)

CLUD:

112663517(ALKBH3)

VVP:	112914443(ALKBH3)

VLG:	121501576(ALKBH3)

NPO:	129494106(ALKBH3)

AML:	100483392(ALKBH3)

UMR:	103672347(ALKBH3)

UAH:	113265015(ALKBH3)

UAR:	123799600(ALKBH3)

ELK:

111150166

LLV:

125079412

MPUF:

101674082(ALKBH3)

MNP:	132008213 132008402

MLK:	131811629(ALKBH3)

NVS:	122912859(ALKBH3)

ORO:	101367649(ALKBH3)

EJU:	114215268(ALKBH3)

ZCA:	113913808(ALKBH3)

MLX:	118016268(ALKBH3)

NSU:	110575738(ALKBH3)

LWW:	102747133(ALKBH3)

FCA:	101082850(ALKBH3)

PYU:	121043520(ALKBH3)

PCOO:

112865460(ALKBH3)

PBG:	122483722(ALKBH3)

PVIV:

125176645(ALKBH3)

LRUF:

124505824

LGF:	123601615(ALKBH3)

AJU:

106978053

PTG:	102963280(ALKBH3)

PPAD:

109279205(ALKBH3)

PUC:

125912836

PLEZ:

122199656(ALKBH3)

HHV:	120228413(ALKBH3)

BTA:	514579(ALKBH3)

BOM:	102274694(ALKBH3)

BIU:	109569676(ALKBH3)

BBUB:

102390815(ALKBH3)

BBIS:

105000307(ALKBH3)

CHX:	102187149(ALKBH3)

OAS:	101110359(ALKBH3)

BTAX:

128060163(ALKBH3)

CSUM:

138092624(ALKBH3)

ODA:	120876904(ALKBH3)

CCAD:

122450095(ALKBH3)

MREE:

136174294(ALKBH3)

OVR:	110146592(ALKBH3)

MBEZ:

129554769(ALKBH3)

SSC:	100624169(ALKBH3)

CFR:	102515170(ALKBH3)

CBAI:

105076492(ALKBH3)

CDK:	105106833(ALKBH3)

VPC:	102543076(ALKBH3)

BACU:

102998891(ALKBH3)

BMUS:

118900009(ALKBH3)

LVE:	103091564(ALKBH3)

OOR:	101280185(ALKBH3)

LALB:

132525845(ALKBH3)

DLE:	111184013(ALKBH3)

PCAD:

102977330(ALKBH3)

PSIU:

116757913(ALKBH3)

NASI:

112402140(ALKBH3)

ECB:	100055568(ALKBH3)

EPZ:	103556453(ALKBH3)

EAI:	106843966(ALKBH3)

MYB:	102263934(ALKBH3)

MYD:	107184435(ALKBH3)

MMYO:

118665114(ALKBH3)

MLF:	102422610(ALKBH3)

MDT:	132241242(ALKBH3)

MYUM:

139018884(ALKBH3)

PKL:	118713577(ALKBH3)

EFUS:

103290864(ALKBH3)

MNA:	107525489(ALKBH3)

DRO:	112303284(ALKBH3)

SHON:

119002962(ALKBH3)

AJM:	119064442(ALKBH3)

PDIC:

114499939(ALKBH3)

PHAS:

123810082(ALKBH3)

MMF:	118627768(ALKBH3)

PPAM:

129081460(ALKBH3)

HAI:	109391971(ALKBH3)

RFQ:	117031275(ALKBH3)

PALE:

102889640(ALKBH3)

PGIG:

120606250(ALKBH3)

PVP:	105289992(ALKBH3)

RAY:	107511889(ALKBH3)

MJV:	108402894(ALKBH3)

TOD:	119255345(ALKBH3)

SARA:

101545936(ALKBH3)

SFUM:

130039417(ALKBH3)

SETR:

126017935(ALKBH3)

LAV:	100670341(ALKBH3)

TMU:

101348315

ETF:	101653877(ALKBH3)

DNM:	101439626(ALKBH3)

MDO:	100013323(ALKBH3)

GAS:	123251680(ALKBH3)

SHR:	100926516(ALKBH3)

AFZ:

127539676

PCW:	110223980(ALKBH3)

TVP:	118854138(ALKBH3)

PBRV:

138163854(ALKBH3)

OAA:	100079123(ALKBH3)

TACU:

119943362(ALKBH3)

GGA:	423169(ALKBH3)

PCOC:

116228989(ALKBH3)

MGP:	100545576(ALKBH3)

CJO:	107314811(ALKBH3)

TPAI:

128086952(ALKBH3)

LMUT:

125695031(ALKBH3)

NMEL:

110402081(ALKBH3)

APLA:

101803990(ALKBH3)

ACYG:

106044148(ALKBH3)

CATA:

118250817(ALKBH3)

AFUL:

116489599(ALKBH3)

TGU:	100220917(ALKBH3)

LSR:	110472035(ALKBH3)

SCAN:

103827001(ALKBH3)

PMOA:

120512571(ALKBH3)

OTC:	121334524(ALKBH3)

PRUF:

121349558(ALKBH3)

ATRC:

139590227(ALKBH3)

GFR:	102039523(ALKBH3)

FAB:	101807443(ALKBH3)

OMA:	130253384(ALKBH3)

PHI:	102106986(ALKBH3)

PMAJ:

107206104(ALKBH3)

CCAE:

111930139(ALKBH3)

CCW:	104688097(ALKBH3)

CBRC:

103620913(ALKBH3)

ACOE:

138111420(ALKBH3)

ETL:	114064859(ALKBH3)

ZAB:	102064160(ALKBH3)

ZLE:	135448403(ALKBH3)

ACHL:

103804349(ALKBH3)

SVG:	106851558(ALKBH3)

MMEA:

130572487(ALKBH3)

HRT:	120754644(ALKBH3)

SATI:

136362488(ALKBH3)

CCIC:

134045330(ALKBH3)

FPG:	101917358(ALKBH3)

FCH:	102056465(ALKBH3)

CCRI:

104155532(ALKBH3)

NNT:	104410311(ALKBH3)

SHAB:

115607336(ALKBH3)

ACUN:

113480635(ALKBH3)

TALA:

104367470(ALKBH3)

ACHC:

115334572(ALKBH3)

HALD:

104324275(ALKBH3)

HLE:	104839722(ALKBH3)

AGEN:

126049421

HHAR:

128139479(ALKBH3)

GCL:

127016888

CSTI:

104560638(ALKBH3)

LDI:	104349545(ALKBH3)

DPUB:

104303048(ALKBH3)

PPUS:

135180165(ALKBH3)

AVIT:

104274782(ALKBH3)

BRHI:

104488160(ALKBH3)

EGZ:	104134097(ALKBH3)

NNI:	104019570(ALKBH3)

PCRI:

104031898(ALKBH3)

PCAO:

104046663(ALKBH3)

PADL:

103921725(ALKBH3)

AFOR:

103897533(ALKBH3)

FGA:	104070497(ALKBH3)

GSTE:

104257560(ALKBH3)

CLV:	102087563(ALKBH3)

MUI:	104545681(ALKBH3)

PGUU:

104463662(ALKBH3)

CMAC:

104483325(ALKBH3)

CUCA:

104067330(ALKBH3)

TEO:	104377610(ALKBH3)

BREG:

104640696(ALKBH3)

OHA:	104330178(ALKBH3)

ACAR:

104527082(ALKBH3)

CPEA:

104390445(ALKBH3)

CVF:	104295885(ALKBH3)

RTD:	128908798(ALKBH3)

CRID:

134514392(ALKBH3)

AAM:	106498339(ALKBH3)

AROW:

112978305(ALKBH3)

NPD:	112943532(ALKBH3)

TGT:	104565057(ALKBH3)

DNE:	112979237(ALKBH3)

SCAM:

104149261(ALKBH3)

ASN:	102379536(ALKBH3)

AMJ:	102559132(ALKBH3)

CPOO:

109321369(ALKBH3)

GGN:	109298938(ALKBH3)

PSS:	102446051(ALKBH3)

CMY:	102946097(ALKBH3)

CCAY:

125638498(ALKBH3)

DCC:	119857851(ALKBH3)

CPIC:

101950462(ALKBH3)

TST:	117876979(ALKBH3)

CABI:

116830762(ALKBH3)

MRV:	120404300(ALKBH3)

ACS:	100557858(alkbh3)

ASAO:

132768512(ALKBH3)

PVT:	110081512(ALKBH3)

SUND:

121936322(ALKBH3)

PBI:	103049891(ALKBH3)

PMUR:

107289669(ALKBH3)

CTIG:

120307966(ALKBH3)

TSR:	106545010(ALKBH3)

PGUT:

117665487(ALKBH3)

APRI:

131187431(ALKBH3)

PTEX:

113440762(ALKBH3)

NSS:	113410224(ALKBH3)

VKO:	123026755(ALKBH3)

PMUA:

114596277(ALKBH3)

PRAF:

128413537(ALKBH3)

ZVI:	118085411(ALKBH3)

HCG:	128339352(ALKBH3)

GJA:	107119117(ALKBH3)

STOW:

125425939(ALKBH3)

EMC:	129325315(ALKBH3)

XLA:	496071(alkbh3.L)

XTR:	100495476(alkbh3)

NPR:	108785848(ALKBH3)

RTEM:

120917034(ALKBH3)

BBUF:

120981146(ALKBH3)

BGAR:

122920137(ALKBH3)

PWL:	138283749(ALKBH3)

MUO:	115468805(ALKBH3)

GSH:	117352284(ALKBH3)

DRE:	792266(alkbh3)

SRX:

107716661

SANH:

107661502 107696266

SGH:	107573924(alkbh3) 107598856

CAUA:

113043364 113066937(alkbh3)

CGIB:

127946686 128013916

PTET:

122330312(alkbh3)

LROH:

127156747(alkbh3)

OMC:	131534815(alkbh3)

PPRM:

120469201(alkbh3)

RKG:	130104469(alkbh3)

MAMB:

125247648(alkbh3)

CIDE:

127507617

CERY:

137014731(alkbh3)

MASI:

127437772

TROS:

130552230(alkbh3)

TDW:	130414571(alkbh3)

MANU:

129433406(alkbh3)

PDAB:

135781469(alkbh3)

IPU:	100528586(alkbh3)

IFU:	128617854(alkbh3)

PHYP:

113529737(alkbh3)

SMEO:

124392890(alkbh3)

TFD:	113654064(alkbh3)

TVC:	132856867(alkbh3)

CGAR:

128544173(alkbh3)

NGRA:

132873416(alkbh3)

TRN:	134321083(alkbh3)

AMEX:

103026192(alkbh3)

CMAO:

118811762(alkbh3)

EEE:	113571858(alkbh3)

CHAR:

105913394(alkbh3)

SPIL:

134094667(alkbh3)

TRU:	101068007(alkbh3)

TFS:	130535909(alkbh3)

TNG:	GSTEN00019672G001

LCO:	104922397(alkbh3)

NCC:

104950558

TBEN:

117497258(alkbh3)

CGOB:

115010259(alkbh3)

PGEO:

117448142(alkbh3)

GACU:

117557472(alkbh3)

EMAC:

134883907(alkbh3)

ELY:	117262634(alkbh3)

EFO:	125887888(alkbh3)

PLEP:

121938181 121950266(alkbh3)

SLUC:

116046802(alkbh3)

ECRA:

117948979(alkbh3)

ESP:	116693583(alkbh3)

PFLV:

114560330(alkbh3)

GAT:	120809369(alkbh3)

PPUG:

119196541(alkbh3)

AFB:	129108403(alkbh3)

CLUM:

117731839(alkbh3)

PSWI:

130194941 130195756

CANA:

137799734(alkbh3)

CVE:	137881673(alkbh3)

MSAM:

119893647(alkbh3)

SCHU:

122874606(alkbh3)

CUD:	121514579(alkbh3)

SPUL:

138613114(alkbh3)

LMIX:

132972932(alkbh3)

ALAT:

119024425(alkbh3)

ASTR:

137593930(alkbh3)

MZE:	101486257(alkbh3)

ONL:	100698973(alkbh3)

OAU:	116313952(alkbh3)

OLA:	101164226(alkbh3)

OML:	112151953(alkbh3)

CSAI:

133443633(alkbh3)

XMA:	102224505(alkbh3)

XCO:	114134553(alkbh3)

XHE:	116710020(alkbh3)

PRET:

103465694(alkbh3)

PFOR:

103152824(alkbh3)

PLAI:

106964818(alkbh3)

PMEI:

106904444(alkbh3)

GAF:	122835862(alkbh3)

PPRL:

129358942(alkbh3)

CVG:	107092180(alkbh3)

CTUL:

119798181(alkbh3)

GMU:	124861177(alkbh3)

NFU:	107374482(alkbh3)

KMR:	108245714(alkbh3)

ALIM:

106529602(alkbh3)

NWH:	119415412(alkbh3)

AOCE:

111567883(alkbh3)

EJA:	138206431(alkbh3)

BFRE:

138619146(alkbh3)

MCEP:

125014327(alkbh3)

CSEM:

103379804(alkbh3)

POV:	109623981(alkbh3)

SSEN:

122775381(alkbh3)

SSOE:

131469490(alkbh3)

HHIP:

117763684(alkbh3)

HSP:	118110022(alkbh3)

PPLT:

128444203(alkbh3)

SMAU:

118315693(alkbh3)

LCF:

108889309

SDU:	111229672(alkbh3)

SLAL:

111650456(alkbh3)

XGL:	120793747(alkbh3)

HCQ:	109513176(alkbh3)

SSCV:

125970945(alkbh3)

SBIA:

133502085(alkbh3)

PEE:	133403357(alkbh3)

PTAO:

133478263(alkbh3)

BPEC:

110160323(alkbh3)

MALB:

109973531(alkbh3)

BSPL:

114857821(alkbh3)

SJO:	128358313(alkbh3)

SSCO:

133981728(alkbh3)

GMH:	115551058(alkbh3)

SASA:

106561092(alkbh3)

STRU:

115197101(alkbh3)

OTW:

112218280

OMY:	110492083(alkbh3)

OGO:	124039647(alkbh3)

ONE:	115121940 115134525(alkbh3)

OKI:	109867581(alkbh3)

OKE:	118396401(alkbh3)

OMM:

135509625

OCLA:

139381356 139407488

SALP:

111962104(alkbh3)

SNH:	120066092(alkbh3)

CCLU:

121532127 121540108

ELS:	105006119(alkbh3)

SFM:	108942111(alkbh3)

PKI:	111859477(alkbh3)

AANG:

118215767(alkbh3)

AROT:

135242692(alkbh3)

CCOG:

133111881(alkbh3)

LOC:	102684577(alkbh3)

PSPA:

121330137(alkbh3)

ARUT:

117432411 117434590

PSEX:

120523169(alkbh3)

LCM:	102354734(ALKBH3)

CMK:	103174969(alkbh3)

CPLA:

122557662(alkbh3)

HOC:	132824262(alkbh3)

LERI:

129705678(alkbh3)

PMRN:

116949621(ALKBH3)

LRJ:	133346906(ALKBH3)

BFO:

BBEL:

CIN:

SPU:

LPIC:

APLC:

AFIL:

AJC:

SKO:

PFLL:

CSCU:

CVS:	136981266 136984640

PTEP:

107437569

LPOL:

106465920

HRO:	HELRODRAFT_185055

LGI:	LOTGIDRAFT_133518

PVUL:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:	111101457 111101679 111101938

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:	106150965 106173692

LLON:

NVE:

EPA:

ATEN:

XEN:

HSY:

RES:

Reference

PMID:16174769

Authors

Lee DH, Jin SG, Cai S, Chen Y, Pfeifer GP, O'Connor TR

Title

Repair of methylation damage in DNA and RNA by mammalian AlkB homologues.

Journal

J Biol Chem 280:39448-59 (2005)
DOI:10.1074/jbc.M509881200

Sequence

[hsa:221120] [mmu:69113]

All links

Ontology (2)   
   GO (2)   
Gene (2161)   
   MGENES (185)   
   RefGene (1975)   
   OC (1)   
All databases (2163)   

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