KEGG   ORTHOLOGY: K10900Help
Entry
K10900                      KO                                     

Name
WRN, RECQL2
Definition
werner syndrome ATP-dependent helicase [EC:3.6.4.12]
Disease
H00296  Defects in RecQ helicases
H01733  Werner syndrome
Brite
Enzymes [BR:ko01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.12  DNA helicase
     K10900  WRN, RECQL2; werner syndrome ATP-dependent helicase
DNA replication proteins [BR:ko03032]
 Eukaryotic Type
  DNA Replication Termination Factors
   Other telomere regulation proteins
    Others
     K10900  WRN, RECQL2; werner syndrome ATP-dependent helicase
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    RecQ family DNA helicases
     K10900  WRN, RECQL2; werner syndrome ATP-dependent helicase
BRITE hierarchy
Genes
HSA: 7486(WRN)
PTR: 472732(WRN)
PPS: 100975088(WRN)
GGO: 101126909(WRN)
PON: 100188896(WRN)
NLE: 100586959(WRN)
MCC: 695678(WRN)
MCF: 102140708(WRN)
CSAB: 103215588(WRN)
RRO: 104668217(WRN)
RBB: 108518678(WRN)
CJC: 100396599(WRN)
SBQ: 101048471(WRN)
MMU: 22427(Wrn)
RNO: 290805(Wrn)
CGE: 100753909(Wrn)
NGI: 103743580(Wrn)
HGL: 101701103 101724469(Wrn)
CCAN: 109697231(Wrn)
OCU: 100341925(WRN)
TUP: 102470583(WRN)
CFA: 493997(WRN)
AML: 100474249
UMR: 103659079 103659100(WRN)
ORO: 101366610(WRN)
FCA: 101095574(WRN)
PTG: 102963326(WRN)
AJU: 106966549(WRN)
BTA: 505061(WRN)
BOM: 102282258(WRN)
BIU: 109553502(WRN)
PHD: 102323939(WRN)
CHX: 102182278(WRN)
OAS: 101106742(WRN)
SSC: 100512139(WRN)
CFR: 102510058(WRN)
CDK: 105095802(WRN)
BACU: 103001086(WRN)
LVE: 103086411(WRN)
OOR: 101286297(WRN)
ECB: 100062021(WRN)
EPZ: 103565518(WRN)
EAI: 106824397(WRN)
MYB: 102239371(WRN)
MYD: 102771349(WRN)
HAI: 109382967(WRN)
RSS: 109457540(WRN)
PALE: 102886512(WRN)
LAV: 100669012(WRN)
TMU: 101345229
MDO: 100019443(WRN)
SHR: 100921189(WRN)
OAA: 100077021(WRN)
GGA: 422505(WRN)
MGP: 100550079(WRN)
CJO: 107313186(WRN)
APLA: 101803062(WRN)
ACYG: 106035204(WRN)
TGU: 100224252(WRN)
GFR: 102042375(WRN)
PHI: 102112392(WRN)
PMAJ: 107203395(WRN)
CCW: 104696833(WRN)
FPG: 101921016(WRN)
FCH: 102052817(WRN)
CLV: 102085535 102089359(WRN)
EGZ: 104134361(WRN)
AAM: 106494833(WRN)
ASN: 102387381(WRN)
AMJ: 102565260(WRN)
PSS: 102450023(WRN)
CMY: 102948137(WRN)
CPIC: 101952893(WRN)
ACS: 100561844(wrn)
PVT: 110087360(WRN)
PBI: 103055412 103066362(WRN)
GJA: 107108055(WRN)
XLA: 398079(wrn.L)
XTR: 734043(wrn)
NPR: 108798838(WRN)
DRE: 569495(wrn)
SANH: 107665470(wrn)
SGH: 107573262
CCAR: 109068098
IPU: 108276782(wrn)
AMEX: 103034404(wrn)
SASA: 106571354(wrn)
ELS: 105021732(wrn)
SFM: 108929909(wrn)
LCM: 102350127(WRN)
CMK: 103187853(wrn)
CIN: 100179894
SPU: 754123
APLC: 110982034
SKO: 102806182
AAG: 5577399
TCA: 658153
DPA: 109542507
NVL: 108568076
API: 100163969
DNX: 107162107
CEL: CELE_F18C5.2(wrn-1)
CBR: CBG02689(Cbr-wrn-1)
CRG: 105342911
MYI: 110463710
OBI: 106867795
LAK: 106151755
EPA: 110243247
ADF: 107339846
HMG: 100213322
ATH: AT5G27680(RECQSIM)
CRB: 17884521
CSAT: 104736747
BRP: 103874517
BOE: 106303202
CPAP: 110815478
CIT: 102608985
TCC: 18600464
GRA: 105761041
DZI: 111277315
GMX: 100793222
VRA: 106772714
VAR: 108324296
CCAJ: 109795385
CAM: 101498592
ADU: 107465319
AIP: 107619384
LJA: Lj5g3v1496740.1(Lj5g3v1496740.1) Lj5g3v1496740.2(Lj5g3v1496740.2) Lj5g3v1496740.3(Lj5g3v1496740.3) Lj5g3v1496740.4(Lj5g3v1496740.4)
LANG: 109354310
FVE: 101312067
PPER: 18773233
PMUM: 103344611
PAVI: 110759223
MDM: 103433925
PXB: 103965315
ZJU: 107411933
CSV: 101221470
CMO: 103494714
MCHA: 111018875
CMAX: 111465434
CMOS: 111444411
CPEP: 111798790
RCU: 8280233
JCU: 105647512
HBR: 110659759
POP: 18098680
JRE: 109009752
VVI: 100257897
SLY: 101250452
SPEN: 107008462
SOT: 102598356
CANN: 107839598
NSY: 104227667
NTO: 104119321
INI: 109155385
SIND: 105168912
OEU: 111408073
HAN: 110929406
LSV: 111880001
DCR: 108205392
BVG: 104890300
SOE: 110794680
NNU: 104598997
OSA: 4337828
DOSA: Os05t0150600-01(Os05g0150600)
OBR: 102719384
BDI: 100821709
ATS: 109766929(LOC109766929) 109782353(LOC109782353)
SBI: 8069503
ZMA: 100382628(umc1959)
SITA: 101776716
PDA: 103718623
EGU: 105032154
MUS: 103993665
ATR: 18440225
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kamath-Loeb AS, Lan L, Nakajima S, Yasui A, Loeb LA
  Title
Werner syndrome protein interacts functionally with translesion DNA polymerases.
  Journal
Proc Natl Acad Sci U S A 104:10394-9 (2007)
DOI:10.1073/pnas.0702513104
  Sequence
[hsa:7486]

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