KEGG   ORTHOLOGY: K11146
Entry
K11146                      KO                                     
Symbol
DHRS3
Name
short-chain dehydrogenase/reductase 3 [EC:1.1.1.300]
Pathway
map00830  Retinol metabolism
map01100  Metabolic pathways
map01240  Biosynthesis of cofactors
Reaction
R08379  retinol: NADP+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K11146  DHRS3; short-chain dehydrogenase/reductase 3
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.300  NADP-retinol dehydrogenase
     K11146  DHRS3; short-chain dehydrogenase/reductase 3
Other DBs
GO: 0052650
Genes
HSA: 9249(DHRS3)
PTR: 737006(DHRS3)
PPS: 100971367(DHRS3)
GGO: 101136764(DHRS3)
PON: 100446028(DHRS3)
NLE: 100599507(DHRS3)
HMH: 116812943(DHRS3)
MCC: 715548(DHRS3)
MCF: 102142015(DHRS3)
MTHB: 126953389
MNI: 105473180(DHRS3)
CSAB: 103225584(DHRS3)
CATY: 105580842(DHRS3)
PANU: 101025196(DHRS3)
TGE: 112634435(DHRS3)
MLEU: 105551362(DHRS3)
RRO: 104668927(DHRS3)
RBB: 108539385(DHRS3)
TFN: 117093295(DHRS3)
PTEH: 111526312(DHRS3)
CANG: 105526532(DHRS3)
CJC: 100386416(DHRS3)
SBQ: 101039627(DHRS3)
CIMI: 108286613(DHRS3)
CSYR: 103276041(DHRS3)
MMUR: 105882703(DHRS3)
LCAT: 123634453(DHRS3)
PCOQ: 105824966(DHRS3)
OGA: 100963630(DHRS3)
MMU: 20148(Dhrs3)
MCAL: 110292172(Dhrs3)
MPAH: 110323041(Dhrs3)
RNO: 313689(Dhrs3)
MCOC: 116096993(Dhrs3)
ANU: 117709140(Dhrs3)
MUN: 110539426(Dhrs3)
CGE: 100756186(Dhrs3)
MAUA: 101840839(Dhrs3)
PROB: 127213384(Dhrs3)
PLEU: 114685519(Dhrs3)
MFOT: 126508156
AAMP: 119817809(Dhrs3)
NGI: 103747479(Dhrs3)
HGL: 101707915(Dhrs3)
CPOC: 100722728(Dhrs3)
CCAN: 109683963(Dhrs3)
DORD: 105999947(Dhrs3)
DSP: 122121413(Dhrs3)
PLOP: 125354593(Dhrs3)
NCAR: 124958517
MMMA: 107155480(Dhrs3)
OCU: 100348969
OPI: 101527011(DHRS3)
TUP: 102502620(DHRS3)
GVR: 103598934(DHRS3)
CFA: 487436(DHRS3)
CLUD: 112659809(DHRS3)
VVP: 112929696(DHRS3)
VLG: 121496751(DHRS3)
NPO: 129513642(DHRS3)
AML: 100481198(DHRS3)
UMR: 103666638(DHRS3)
UAH: 113270489(DHRS3)
UAR: 123779613(DHRS3)
ELK: 111154760
LLV: 125097812
MPUF: 101687558(DHRS3)
MNP: 132001364(DHRS3)
MLK: 131808935(DHRS3)
NVS: 122899471(DHRS3)
ORO: 101370738(DHRS3)
EJU: 114213406(DHRS3)
ZCA: 113933963(DHRS3)
MLX: 118019991(DHRS3)
NSU: 110574679(DHRS3)
LWW: 102731138(DHRS3)
FCA: 101080307(DHRS3)
PYU: 121021411(DHRS3)
PCOO: 112872083(DHRS3)
PBG: 122479945(DHRS3)
PTG: 102970609(DHRS3)
PPAD: 109274137(DHRS3)
PUC: 125913099
AJU: 106988168
HHV: 120224913(DHRS3)
BTA: 281482(DHRS3)
BOM: 102265772(DHRS3)
BIU: 109570447(DHRS3)
BBUB: 102404826(DHRS3)
BBIS: 104995824(DHRS3)
CHX: 102179583(DHRS3)
OAS: 101109288(DHRS3)
BTAX: 128061372(DHRS3)
ODA: 120880238(DHRS3)
CCAD: 122451887(DHRS3)
MBEZ: 129551554(DHRS3)
SSC: 100514967(DHRS3)
CFR: 102524578(DHRS3)
CBAI: 105070956(DHRS3)
CDK: 105107044(DHRS3)
VPC: 102535527(DHRS3)
BACU: 103018059(DHRS3)
LVE: 103082238(DHRS3)
OOR: 101290385(DHRS3)
DLE: 111187101(DHRS3)
PCAD: 102982136(DHRS3)
PSIU: 116738948(DHRS3)
NASI: 112402728(DHRS3)
ECB: 100055537(DHRS3)
EPZ: 103552172(DHRS3)
EAI: 106836659(DHRS3)
MYB: 102248154(DHRS3)
MYD: 102762827(DHRS3)
MMYO: 118676160(DHRS3)
MLF: 102417911(DHRS3)
MNA: 107531562(DHRS3)
PKL: 118731971(DHRS3)
EFUS: 103295338(DHRS3)
HAI: 109381266(DHRS3)
DRO: 112299121(DHRS3)
SHON: 118986332(DHRS3)
AJM: 119064076(DHRS3)
PDIC: 114496658(DHRS3)
PHAS: 123831663(DHRS3)
MMF: 118627175(DHRS3)
RFQ: 117026905(DHRS3)
PPAM: 129075644(DHRS3)
PALE: 102880345(DHRS3)
PGIG: 120585801(DHRS3)
PVP: 105294422(DHRS3)
RAY: 107513138(DHRS3)
MJV: 108402930(DHRS3)
TOD: 119236996(DHRS3)
SARA: 101558421(DHRS3)
LAV: 100656973(DHRS3)
TMU: 101360145
ETF: 101661630(DHRS3)
DNM: 101417782(DHRS3)
MDO: 100010099(DHRS3)
GAS: 123240318(DHRS3)
SHR: 100913855(DHRS3)
AFZ: 127555853
PCW: 110198918(DHRS3)
OAA: 100090663(DHRS3)
GGA: 419480(DHRS3)
PCOC: 116242686(DHRS3)
MGP: 100541886(DHRS3)
CJO: 107323359(DHRS3)
TPAI: 128084920(DHRS3)
LMUT: 125703520(DHRS3)
NMEL: 110408680(DHRS3)
APLA: 101792259(DHRS3)
ACYG: 106040190(DHRS3)
CATA: 118253419(DHRS3)
AFUL: 116497552(DHRS3)
TGU: 100221618(DHRS3)
LSR: 110476789(DHRS3)
SCAN: 103820840(DHRS3)
PMOA: 120496756(DHRS3)
OTC: 121343945(DHRS3)
PRUF: 121358418(DHRS3)
GFR: 102032402(DHRS3)
FAB: 101814379(DHRS3)
OMA: 130261553(DHRS3)
PHI: 102110985(DHRS3)
PMAJ: 107213682(DHRS3)
CCAE: 111938724(DHRS3)
CCW: 104693251(DHRS3)
CBRC: 103616129(DHRS3)
ETL: 114065123(DHRS3)
ZAB: 102072789(DHRS3)
ACHL: 103808420(DHRS3)
SVG: 106856391(DHRS3)
MMEA: 130583467(DHRS3)
HRT: 120762269(DHRS3)
FPG: 101921484(DHRS3)
FCH: 102058887(DHRS3)
CLV: 102087489(DHRS3)
EGZ: 104133092(DHRS3)
NNI: 104009010(DHRS3)
PCRI: 104030284(DHRS3)
PLET: 104622674(DHRS3)
EHS: 104506231(DHRS3)
PCAO: 104051518(DHRS3)
ACUN: 113487888(DHRS3)
TALA: 104357145(DHRS3)
PADL: 103917993(DHRS3)
AFOR: 103907433(DHRS3)
ACHC: 115342535(DHRS3)
HALD: 104316790(DHRS3)
HLE: 104837875(DHRS3)
AGEN: 126043195
GCL: 127024694
CCRI: 104162952(DHRS3)
CSTI: 104563532(DHRS3)
CMAC: 104483002(DHRS3)
MUI: 104544714(DHRS3)
BREG: 104643166(DHRS3)
FGA: 104071389(DHRS3)
GSTE: 104252143(DHRS3)
LDI: 104341467(DHRS3)
MNB: 103774108(DHRS3)
OHA: 104332601(DHRS3)
NNT: 104403886(DHRS3)
SHAB: 115617558(DHRS3)
DPUB: 104305829(DHRS3)
PGUU: 104462147(DHRS3)
ACAR: 104529502(DHRS3)
CPEA: 104395427(DHRS3)
AVIT: 104269010(DHRS3)
CVF: 104282942(DHRS3)
RTD: 128918294(DHRS3)
CUCA: 104060564(DHRS3)
TEO: 104381116(DHRS3)
BRHI: 104496439(DHRS3)
AAM: 106482457(DHRS3)
AROW: 112970126(DHRS3)
NPD: 112959634(DHRS3)
TGT: 104570931(DHRS3)
DNE: 112980559(DHRS3)
SCAM: 104141848(DHRS3)
ASN: 102370531(DHRS3)
AMJ: 102574201(DHRS3)
CPOO: 109314392(DHRS3)
GGN: 109293769(DHRS3)
PSS: 102445977(DHRS3)
CMY: 102944040(DHRS3)
CCAY: 125624544(DHRS3)
DCC: 119845196(DHRS3)
CPIC: 101941293(DHRS3)
TST: 117867783(DHRS3)
CABI: 116821896(DHRS3)
MRV: 120387748(DHRS3)
ACS: 100557137(dhrs3)
ASAO: 132764755(DHRS3)
PVT: 110082458(DHRS3)
SUND: 121936546(DHRS3)
PBI: 103054360(DHRS3)
PMUR: 107284674(DHRS3)
CTIG: 120319156(DHRS3)
TSR: 106555968
PGUT: 117656603(DHRS3)
APRI: 131187147(DHRS3)
PTEX: 113450786(DHRS3)
NSS: 113430539(DHRS3)
VKO: 123034700(DHRS3)
PMUA: 114602606(DHRS3)
PRAF: 128419634(DHRS3)
ZVI: 118086593(DHRS3)
HCG: 128338540(DHRS3)
GJA: 107124081(DHRS3)
STOW: 125445782(DHRS3)
EMC: 129344734(DHRS3)
XLA: 108697667(dhrs3.S) 444269(dhrs3.L)
XTR: 493258(dhrs3)
NPR: 108783931(DHRS3)
RTEM: 120915789(DHRS3)
BBUF: 120998361(DHRS3)
BGAR: 122928885(DHRS3)
MUO: 115456552(DHRS3)
GSH: 117349434(DHRS3)
DRE: 445083(dhrs3a) 450050(dhrs3b)
PTET: 122328450(dhrs3a) 122354472(dhrs3b)
LROH: 127155242(dhrs3a) 127172836(dhrs3b)
OMC: 131531510(dhrs3a) 131548900(dhrs3b)
PPRM: 120462751(dhrs3a) 120480236(dhrs3b)
RKG: 130085568(dhrs3b) 130102186(dhrs3a)
MAMB: 125256890(dhrs3b) 125260260(dhrs3a)
TROS: 130545182(dhrs3a) 130571716(dhrs3b)
TDW: 130409438(dhrs3a) 130410748(dhrs3b)
MANU: 129427553(dhrs3b) 129431000(dhrs3a)
IPU: 108255144(dhrs3b) 108275517(dhrs3a)
IFU: 128619005(dhrs3a) 128625045(dhrs3b)
PHYP: 113530392 113537937(dhrs3)
TFD: 113656474(dhrs3b) 113658105(dhrs3a)
TVC: 132837761(dhrs3b) 132862725(dhrs3a)
AMEX: 103042050(dhrs3) 103044922
CMAO: 118799509(dhrs3b) 118822999(dhrs3a)
CHAR: 105894275(dhrs3a) 105912206(dhrs3b)
TRU: 101064046(dhrs3)
TFS: 130524543(dhrs3b)
LCO: 104917935(dhrs3)
NCC: 104955652(dhrs3)
TBEN: 117489360(dhrs3b)
CGOB: 115007670(dhrs3)
PGEO: 117447325(dhrs3b)
GACU: 117539471(dhrs3b)
ELY: 117256430(dhrs3b)
EFO: 125897523(dhrs3b)
PLEP: 121950706(dhrs3b)
SLUC: 116051562(dhrs3b)
ECRA: 117943810(dhrs3b)
ESP: 116687925(dhrs3)
PFLV: 114554569(dhrs3)
GAT: 120835162(dhrs3b)
PPUG: 119194272(dhrs3b)
AFB: 129106035(dhrs3b)
CLUM: 117731149(dhrs3b)
MSAM: 119886682(dhrs3b)
SCHU: 122862746(dhrs3b)
CUD: 121507446(dhrs3b)
ALAT: 119021690(dhrs3b)
MZE: 101486960(dhrs3)
ONL: 100711752(dhrs3)
OAU: 116315043(dhrs3b)
OLA: 101159580(dhrs3)
OML: 112144521(dhrs3b)
XMA: 102237356(dhrs3)
XCO: 114135360(dhrs3)
XHE: 116710060(dhrs3)
PRET: 103464767(dhrs3)
PFOR: 103134657(dhrs3)
PLAI: 106951996(dhrs3)
PMEI: 106929712(dhrs3)
GAF: 122833705(dhrs3b)
PPRL: 129372883(dhrs3b)
CVG: 107085136(dhrs3)
CTUL: 119780742(dhrs3b)
GMU: 124856614(dhrs3b)
NFU: 107384894(dhrs3)
KMR: 108231475(dhrs3b)
ALIM: 106518344(dhrs3)
NWH: 119412626(dhrs3b)
AOCE: 111581142(dhrs3)
MCEP: 125007388(dhrs3b)
CSEM: 103386641(dhrs3)
POV: 109635620(dhrs3)
SSEN: 122767833(dhrs3b)
HHIP: 117761746(dhrs3b)
HSP: 118105483(dhrs3b)
LCF: 108885195(dhrs3b)
SDU: 111233594(dhrs3)
SLAL: 111660657(dhrs3)
XGL: 120807538(dhrs3b)
HCQ: 109521619(dhrs3)
SSCV: 125977522
SBIA: 133508024(dhrs3b)
PEE: 133409052(dhrs3b)
PTAO: 133483908(dhrs3b)
BPEC: 110174741(dhrs3)
MALB: 109972345(dhrs3)
BSPL: 114855329(dhrs3b)
SJO: 128355698(dhrs3b)
ELS: 105013897(dhrs3)
AANG: 118208501 118211933(dhrs3b)
LOC: 102697001(dhrs3)
PSEX: 120530803(dhrs3b)
LCM: 102361459(DHRS3)
CMK: 103172070
RTP: 109924401(dhrs3)
CPLA: 122540237
HOC: 132833720
LERI: 129711452
PMRN: 116950500(DHRS3)
LRJ: 133352398(DHRS3)
BBEL: 109473967
SKO: 100375139
BGT: 106057475
CRG: 105320167
CVN: 111132140
CANU: 128188292
OED: 125662998
MYI: 110462738
PMAX: 117314839
MMER: 123527156
RPHI: 132726560
OBI: 106870606
 » show all
Reference
PMID:9705317
  Authors
Haeseleer F, Huang J, Lebioda L, Saari JC, Palczewski K
  Title
Molecular characterization of a novel short-chain dehydrogenase/reductase that reduces all-trans-retinal.
  Journal
J Biol Chem 273:21790-9 (1998)
DOI:10.1074/jbc.273.34.21790
  Sequence
[hsa:9249] [mmu:20148] [bta:281482]

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