KEGG   ORTHOLOGY: K11220
Entry
K11220                      KO                                     
Symbol
STAT1
Name
signal transducer and activator of transcription 1
Pathway
map04062  Chemokine signaling pathway
map04217  Necroptosis
map04380  Osteoclast differentiation
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04625  C-type lectin receptor signaling pathway
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04917  Prolactin signaling pathway
map04919  Thyroid hormone signaling pathway
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map05140  Leishmaniasis
map05145  Toxoplasmosis
map05152  Tuberculosis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05164  Influenza A
map05165  Human papillomavirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05212  Pancreatic cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05321  Inflammatory bowel disease
Disease
H00089  IFN-gamma/IL-12 axis
H01109  Chronic mucocutaneous candidiasis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11220  STAT1; signal transducer and activator of transcription 1
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04621 NOD-like receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04625 C-type lectin receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04658 Th1 and Th2 cell differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
   04659 Th17 cell differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
   04062 Chemokine signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04935 Growth hormone synthesis, secretion and action
    K11220  STAT1; signal transducer and activator of transcription 1
   04919 Thyroid hormone signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11220  STAT1; signal transducer and activator of transcription 1
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K11220  STAT1; signal transducer and activator of transcription 1
  09162 Cancer: specific types
   05212 Pancreatic cancer
    K11220  STAT1; signal transducer and activator of transcription 1
  09172 Infectious disease: viral
   05161 Hepatitis B
    K11220  STAT1; signal transducer and activator of transcription 1
   05160 Hepatitis C
    K11220  STAT1; signal transducer and activator of transcription 1
   05171 Coronavirus disease - COVID-19
    K11220  STAT1; signal transducer and activator of transcription 1
   05164 Influenza A
    K11220  STAT1; signal transducer and activator of transcription 1
   05162 Measles
    K11220  STAT1; signal transducer and activator of transcription 1
   05168 Herpes simplex virus 1 infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05169 Epstein-Barr virus infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05165 Human papillomavirus infection
    K11220  STAT1; signal transducer and activator of transcription 1
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K11220  STAT1; signal transducer and activator of transcription 1
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K11220  STAT1; signal transducer and activator of transcription 1
   05140 Leishmaniasis
    K11220  STAT1; signal transducer and activator of transcription 1
  09163 Immune disease
   05321 Inflammatory bowel disease
    K11220  STAT1; signal transducer and activator of transcription 1
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K11220  STAT1; signal transducer and activator of transcription 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11220  STAT1; signal transducer and activator of transcription 1
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11220  STAT1; signal transducer and activator of transcription 1
Genes
HSA: 6772(STAT1)
PTR: 459834(STAT1)
PPS: 100971620(STAT1)
GGO: 101131770(STAT1)
PON: 100173683(STAT1)
PPYG: 129031864(STAT1)
NLE: 100596344(STAT1)
HMH: 116810529(STAT1)
SSYN: 129488190(STAT1)
MCC: 693650(STAT1)
MCF: 101925134(STAT1)
MTHB: 126932637
MNI: 105468204(STAT1)
CSAB: 103217529(STAT1)
CATY: 105579958(STAT1)
PANU: 101005886(STAT1)
TGE: 112635950(STAT1)
MLEU: 105535217(STAT1)
RRO: 104675282(STAT1)
RBB: 108527866(STAT1)
TFN: 117094713(STAT1)
PTEH: 111546340(STAT1)
CANG: 105507777(STAT1)
CJC: 100401630(STAT1)
SBQ: 101030811(STAT1)
CIMI: 108284049(STAT1)
ANAN: 105710132(STAT1)
CSYR: 103256404(STAT1)
MMUR: 105877906(STAT1)
LCAT: 123643619(STAT1)
PCOQ: 105813290(STAT1)
OGA: 100956762(STAT1)
MMU: 20846(Stat1)
MCAL: 110304843(Stat1)
MPAH: 110321139(Stat1)
RNO: 25124(Stat1)
MCOC: 116088407(Stat1)
ANU: 117705244(Stat1)
MUN: 110552020(Stat1)
CGE: 100755609(Stat1)
MAUA: 101827798(Stat1)
PROB: 127226208(Stat1)
PLEU: 114705035(Stat1)
MORG: 121442179 121458866
MFOT: 126511873
AAMP: 119803912(Stat1)
NGI: 103736156(Stat1)
HGL: 101718902(Stat1)
CPOC: 100724708(Stat1)
CCAN: 109679865 109682738(Stat1)
DORD: 105995197(Stat1)
DSP: 122115055(Stat1)
PLOP: 125350458(Stat1)
NCAR: 124979200
MMMA: 107138551(Stat1)
OCU: 100343893 127488928
OPI: 101525476(STAT1)
TUP: 102476590(STAT1)
GVR: 103588074(STAT1)
CFA: 488449(STAT1)
CLUD: 112656324(STAT1)
VVP: 112922923(STAT1)
VLG: 121480638(STAT1)
NPO: 129522804(STAT1)
AML: 100474026(STAT1)
UMR: 103659933(STAT1)
UAH: 113250654(STAT1)
UAR: 123798145(STAT1)
ELK: 111144592
LLV: 125095018
MPUF: 101686596(STAT1)
MNP: 132013398(STAT1)
MLK: 131827656(STAT1)
NVS: 122902129(STAT1)
ORO: 101378785(STAT1)
EJU: 114223921(STAT1)
ZCA: 113919574(STAT1)
MLX: 118012204(STAT1)
NSU: 110592138(STAT1)
LWW: 102731818(STAT1)
FCA: 101084561(STAT1)
PYU: 121030838(STAT1)
PCOO: 112869860(STAT1)
PBG: 122481579(STAT1)
PVIV: 125173414(STAT1)
LRUF: 124515343
PTG: 102953174(STAT1)
PPAD: 109274693(STAT1)
PUC: 125911435
AJU: 106979712
HHV: 120233455(STAT1)
BTA: 510814(STAT1)
BOM: 102283508(STAT1)
BIU: 109568771(STAT1)
BBUB: 102415500(STAT1)
BBIS: 105003595(STAT1)
CHX: 102189170(STAT1)
OAS: 100307049(STAT1)
BTAX: 128071221(STAT1)
ODA: 120854684(STAT1)
CCAD: 122426277(STAT1)
MBEZ: 129537915(STAT1)
SSC: 396655(STAT1)
CFR: 102509999(STAT1)
CBAI: 105063982(STAT1)
CDK: 105088783(STAT1)
VPC: 102544679(STAT1)
BACU: 103013781
BMUS: 118898022(STAT1)
LVE: 103069117
OOR: 101272458(STAT1)
DLE: 111171663(STAT1)
PCAD: 102977655(STAT1)
PSIU: 116757187(STAT1)
NASI: 112392137(STAT1)
ECB: 100069633(STAT1)
EPZ: 103548655(STAT1)
EAI: 106828796(STAT1)
MYB: 102243651(STAT1)
MYD: 102757059(STAT1)
MMYO: 118661220(STAT1)
MLF: 102424662(STAT1)
PKL: 118709492(STAT1)
EFUS: 103290572(STAT1)
MNA: 107540521(STAT1)
DRO: 112307780(STAT1)
SHON: 118985299(STAT1)
AJM: 119062093(STAT1)
PDIC: 114494120(STAT1)
PHAS: 123816523(STAT1)
MMF: 118625659(STAT1)
PPAM: 129065467(STAT1)
HAI: 109393276(STAT1)
RFQ: 117025725(STAT1)
PALE: 102886603(STAT1)
PGIG: 120587473(STAT1)
PVP: 105289309(STAT1)
RAY: 107519182(STAT1)
MJV: 108400080(STAT1)
TOD: 119256041(STAT1)
SARA: 101554357(STAT1)
SETR: 126009005(STAT1)
LAV: 100668424(STAT1)
TMU: 101357916
ETF: 101650838(STAT1)
DNM: 101436399(STAT1)
MDO: 100028917(STAT1)
GAS: 123242151(STAT1)
SHR: 105749862(STAT1)
AFZ: 127554459
PCW: 110213248(STAT1)
TVP: 118836098(STAT1)
OAA: 100087266(STAT1)
GGA: 424044(STAT1)
PCOC: 116235961(STAT1)
MGP: 100544816(STAT1)
CJO: 107316322(STAT1)
TPAI: 128077102(STAT1)
LMUT: 125697226(STAT1)
NMEL: 110399457(STAT1)
APLA: 101795022(STAT1)
ACYG: 106039967(STAT1)
CATA: 118261546(STAT1)
AFUL: 116490500(STAT1)
TGU: 100221342(STAT1)
LSR: 110471109(STAT1)
SCAN: 103814539(STAT1)
PMOA: 120511477(STAT1)
OTC: 121335389(STAT1)
PRUF: 121364380(STAT1)
GFR: 102036007(STAT1)
FAB: 101811260(STAT1)
OMA: 130255273(STAT1)
PHI: 102100816(STAT1)
PMAJ: 107207405(STAT1)
CCAE: 111931930(STAT1)
CCW: 104693738(STAT1)
CBRC: 103612443(STAT1)
ETL: 114057449(STAT1)
ZAB: 102075199(STAT1)
ZLE: 135450153(STAT1)
ACHL: 103800628(STAT1)
SVG: 106855910(STAT1)
MMEA: 130578196(STAT1)
HRT: 120755497(STAT1)
FPG: 101922205(STAT1)
FCH: 102054689(STAT1)
CLV: 102098106(STAT1)
EGZ: 104130544(STAT1)
NNI: 104014274(STAT1)
PCRI: 104024447(STAT1)
PLET: 104619945(STAT1)
EHS: 104508311(STAT1)
PCAO: 104041888(STAT1)
ACUN: 113482458(STAT1)
TALA: 104362790(STAT1)
PADL: 103925472(STAT1)
AFOR: 103897147(STAT1)
ACHC: 115342511(STAT1)
HALD: 104324347(STAT1)
HLE: 104829588(STAT1)
AGEN: 126042725
GCL: 127018115
CCRI: 104167043(STAT1)
CSTI: 104560273(STAT1)
CMAC: 104485862(STAT1)
MUI: 104544870
BREG: 104643105(STAT1)
FGA: 104077124(STAT1)
GSTE: 104259693(STAT1)
LDI: 104351582(STAT1)
OHA: 104328394(STAT1)
NNT: 104413420(STAT1)
SHAB: 115608872(STAT1)
DPUB: 104309847(STAT1)
PGUU: 104457917(STAT1)
ACAR: 104525996(STAT1)
CPEA: 104386613(STAT1)
CVF: 104290959(STAT1)
RTD: 128913182(STAT1)
CUCA: 104058327(STAT1)
TEO: 104381035(STAT1)
BRHI: 104491544(STAT1)
AAM: 106492439(STAT1)
AROW: 112978333(STAT1)
NPD: 112954430(STAT1)
TGT: 104565536(STAT1)
DNE: 112982588(STAT1)
SCAM: 104143404(STAT1)
ASN: 102374439(STAT1)
AMJ: 102571738(STAT1)
CPOO: 109323031(STAT1)
GGN: 109301851(STAT1)
PSS: 102462741(STAT1)
CMY: 102934663(STAT1)
CCAY: 125644935(STAT1)
DCC: 119863823(STAT1)
CPIC: 101931440(STAT1)
TST: 117884619(STAT1)
CABI: 116815204(STAT1)
MRV: 120374631(STAT1)
ACS: 100558595(stat1)
ASAO: 132778013(STAT1)
PVT: 110083952(STAT1)
SUND: 121935257(STAT1)
PBI: 103060112(STAT1)
PMUR: 107289220(STAT1)
CTIG: 120298332(STAT1)
TSR: 106537889(STAT1)
PGUT: 117672712(STAT1)
APRI: 131201014(STAT1)
PTEX: 113433994(STAT1)
NSS: 113412400(STAT1)
VKO: 123021819(STAT1)
PMUA: 114607449(STAT1)
PRAF: 128399344(STAT1)
ZVI: 118095191(STAT1)
HCG: 128335373(STAT1)
EMC: 129323801(STAT1)
XLA: 108703082(stat1.S) 398324(stat1.L)
XTR: 780397(stat1)
NPR: 108798858(STAT1)
RTEM: 120943691(STAT1)
BBUF: 121008988(STAT1)
BGAR: 122945284(STAT1)
MUO: 115473779(STAT1)
GSH: 117360731(STAT1)
DRE: 30768(stat1a) 368481(stat1b)
SRX: 107714382 107728932 107739326 107754245
SANH: 107653597 107657528(stat1) 107660594 107687870
SGH: 107565020 107586991 107600977 107602152
CCAR: 109046557 109081472 109095780
CAUA: 113039565 113040769 113053015 113064788 113108355 113108356
CGIB: 127942720 127965590 127965593 127987405 128020154
PTET: 122327842(stat1a) 122351700(stat1b)
LROH: 127153806(stat1a) 127170576(stat1b) 127170859
OMC: 131531449(stat1a)
PPRM: 120477609 120477802(stat1b) 120486276(stat1a)
RKG: 130072558(stat1b) 130072594 130100395(stat1a)
MAMB: 125254061(stat1a) 125270612(stat1b)
CIDE: 127519048 127519050 127519975
MASI: 127438039 127438769 127447213 127448086
TROS: 130549106(stat1a) 130555682(stat1b)
TDW: 130427429(stat1b) 130430030(stat1a)
MANU: 129452652 129454249(stat1a)
IPU: 108259490(stat1a) 108266311(stat1b)
IFU: 128602760(stat1a) 128608451(stat1b)
PHYP: 113524282 113526011
SMEO: 124379860(stat1a) 124383399 124383401
TFD: 113651885(stat1a) 113657095(stat1b) 113661254 113661265
TVC: 132838889(stat1a) 132850464 132850466(stat1b)
TRN: 134304237(stat1a) 134324528
AMEX: 103028874(stat1a) 103031000(stat1b)
CMAO: 118801704(stat1a) 118809414 118821121(stat1b)
EEE: 113581352(stat1) 113586831
CHAR: 105905676(stat1a) 105913246 105913247 105913248
TRU: 101068828(stat1) 101079646
TFS: 130522341(stat1a) 130523302
TNG: GSTEN00027249G001 GSTEN00031849G001 GSTEN00033158G001
LCO: 104920795 104926239
NCC: 104949635
TBEN: 117469171 117485957(stat1b) 117499191(stat1a)
CGOB: 115017314 115026732
PGEO: 117441669(stat1a) 117466574
GACU: 117549497 117549793(stat1a)
EMAC: 134861047(stat1a) 134867158
ELY: 117249488 117250238(stat1a)
EFO: 125884694(stat1a) 125899274
PLEP: 121948957 121962658
SLUC: 116043142(stat1b) 116053691(stat1a)
ECRA: 117939468(stat1a) 117953178
ESP: 116674022(stat1) 116698329
PFLV: 114550696 114564150
GAT: 120826627(stat1a) 120834093
PPUG: 119220035(stat1a)
AFB: 129104815 129111532(stat1a)
CLUM: 117741800(stat1a)
PSWI: 130204372 130204505
MSAM: 119884527 119900506(stat1a) 119903420
SCHU: 122871839(stat1a) 122885811
CUD: 121506226(stat1a) 121522933
ALAT: 119015223(stat1a) 119025600
MZE: 101476764(stat1) 101486905
ONL: 100696359(stat1) 100709564
OAU: 116309467 116317095(stat1a)
OLA: 101154761 101158490
OML: 112154777 112156680(stat1a)
CSAI: 133425311(stat1a)
XMA: 102225755 102237914
XCO: 114140546 114148403
XHE: 116715660 116723258
PRET: 103457785(stat1) 103460709
PFOR: 103130104(stat1) 103130271
PLAI: 106942383(stat1) 106951655
PMEI: 106907676 106909973(stat1)
GAF: 122827058(stat1a) 122840006
PPRL: 129356612(stat1a)
CVG: 107080778 107092284(stat1)
CTUL: 119792770
GMU: 124861925(stat1a) 124870924
NFU: 107384662(stat1) 107397172
KMR: 108229342(stat1a) 108250770
ALIM: 106531438(stat1)
NWH: 119419796 119428888(stat1a)
AOCE: 111563285 111572427
MCEP: 125000988(stat1a) 125017356
CSEM: 103389515(stat1) 103392403
POV: 109637376 109640914
SSEN: 122758564 122763091(stat1a)
HHIP: 117754943 117774286(stat1a)
HSP: 118103226 118119965
PPLT: 128430991 128455436
SMAU: 118282950 118318615
LCF: 108873137 108879807 108879808 108897177
SDU: 111218101 111222701(stat1)
SLAL: 111667430 111672441
XGL: 120798154(stat1a) 120801616
HCQ: 109517578 109520194(stat1)
SSCV: 125988268
SBIA: 133505793(stat1a)
PEE: 133402577(stat1a)
PTAO: 133478909(stat1a)
BPEC: 110156119 110156121 110175594(stat1)
MALB: 109955685(stat1)
BSPL: 114845713(stat1a) 114846801
SJO: 128354436(stat1a) 128367733
SASA: 100136558(STAT1) 106586142
STRU: 115156118 115160666 115195984
OTW: 112235369 112244575(stat1b) 112253779 112253897 112253955
OMY: 100136755(stat1-1) 100137016(stat1-2) 110501544(stat1b) 110520020 110527523
OGO: 124007667 124007940 124011634 124043794
ONE: 115108041 115129673 115133971 115133986 115138513
OKI: 109865728 109871062 109890649 109906681
OKE: 118363713 118367154 118370180 118383626 118385792
SALP: 111970963 111973973 111974236 112067758
SNH: 120033389 120051252 120058211 120064425(stat1b)
CCLU: 121536664 121551541(stat1b) 121562465 121562466 121562503 121568070 123481194 123485102
ELS: 105022417 105022492 105022527
SFM: 108924273 108929360
PKI: 111842948 111845415(stat1)
AANG: 118214287 118223245
LOC: 102685821(stat1)
PSPA: 121322145 121322927
ARUT: 117409265 117426624
PSEX: 120522445
LCM: 102353760(STAT1)
CMK: 103176541
RTP: 109920367
CPLA: 122543210 122551254
HOC: 132805837 132817161
LERI: 129698644 129714674
PMRN: 116938726(STAT1)
LRJ: 133345932(STAT1)
 » show all
Reference
PMID:1502203
  Authors
Schindler C, Fu XY, Improta T, Aebersold R, Darnell JE Jr
  Title
Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha.
  Journal
Proc Natl Acad Sci U S A 89:7836-9 (1992)
DOI:10.1073/pnas.89.16.7836
  Sequence
[hsa:6772]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (58)   
   KEGG PATHWAY (58)   
Disease (2)   
   KEGG DISEASE (2)   
Gene (1081)   
   KEGG GENES (564)   
   KEGG MGENES (344)   
   RefGene (169)   
   OC (4)   
Literature (1)   
   PubMed (1)   
All databases (1144)   

Download RDF
DBGET integrated database retrieval system