KEGG   ORTHOLOGY: K11220Help
Entry
K11220                      KO                                     

Name
STAT1
Definition
signal transducer and activator of transcription 1
Pathway
ko04062  Chemokine signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04625  C-type lectin receptor signaling pathway
ko04630  Jak-STAT signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04917  Prolactin signaling pathway
ko04919  Thyroid hormone signaling pathway
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05140  Leishmaniasis
ko05145  Toxoplasmosis
ko05152  Tuberculosis
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi's sarcoma-associated herpesvirus infection
ko05168  Herpes simplex infection
ko05200  Pathways in cancer
ko05212  Pancreatic cancer
ko05321  Inflammatory bowel disease (IBD)
Module
M00684  JAK-STAT signaling
Disease
H00089  IFN-gamma/IL-12 axis
H00363  Candidiasis
H01109  Chronic mucocutaneous candidiasis (CMC)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
 Cellular Processes
  Cell growth and death
   04217 Necroptosis
    K11220  STAT1; signal transducer and activator of transcription 1
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04621 NOD-like receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04625 C-type lectin receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04658 Th1 and Th2 cell differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
   04659 Th17 cell differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
   04062 Chemokine signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
  Endocrine system
   04917 Prolactin signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04919 Thyroid hormone signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
  Development
   04380 Osteoclast differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K11220  STAT1; signal transducer and activator of transcription 1
   05212 Pancreatic cancer
    K11220  STAT1; signal transducer and activator of transcription 1
  Immune diseases
   05321 Inflammatiory bowel disease (IBD)
    K11220  STAT1; signal transducer and activator of transcription 1
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    K11220  STAT1; signal transducer and activator of transcription 1
  Infectious diseases
   05152 Tuberculosis
    K11220  STAT1; signal transducer and activator of transcription 1
   05162 Measles
    K11220  STAT1; signal transducer and activator of transcription 1
   05164 Influenza A
    K11220  STAT1; signal transducer and activator of transcription 1
   05161 Hepatitis B
    K11220  STAT1; signal transducer and activator of transcription 1
   05160 Hepatitis C
    K11220  STAT1; signal transducer and activator of transcription 1
   05168 Herpes simplex infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05165 Human papillomavirus infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05145 Toxoplasmosis
    K11220  STAT1; signal transducer and activator of transcription 1
   05140 Leishmaniasis
    K11220  STAT1; signal transducer and activator of transcription 1
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00684  JAK-STAT signaling
     K11220  STAT1; signal transducer and activator of transcription 1
Transcription factors [BR:ko03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11220  STAT1; signal transducer and activator of transcription 1
BRITE hierarchy
Genes
HSA: 6772(STAT1)
PTR: 459834(STAT1)
PPS: 100971620(STAT1)
GGO: 101131770(STAT1)
PON: 100173683(STAT1)
NLE: 100596344(STAT1)
MCC: 693650(STAT1)
MCF: 101925134(STAT1)
CSAB: 103217529(STAT1)
RRO: 104675282(STAT1)
RBB: 108527866(STAT1)
CJC: 100401630(STAT1)
SBQ: 101030811(STAT1)
MMU: 20846(Stat1)
RNO: 25124(Stat1)
CGE: 100755609(Stat1)
NGI: 103736156(Stat1)
HGL: 101718902(Stat1)
CCAN: 109679865 109682738(Stat1)
OCU: 100343893(STAT1)
TUP: 102476590(STAT1)
CFA: 488449(STAT1)
AML: 100474026(STAT1)
UMR: 103659933(STAT1)
ORO: 101378785(STAT1)
FCA: 101084561(STAT1)
PTG: 102953174(STAT1)
AJU: 106979712(STAT1)
BTA: 510814(STAT1)
BOM: 102283508(STAT1)
BIU: 109568771(STAT1)
PHD: 102331890
CHX: 102189170(STAT1)
OAS: 100307049(STAT1)
SSC: 396655(STAT1)
CFR: 102509999(STAT1)
CDK: 105088783(STAT1)
BACU: 103013781
LVE: 103069117
OOR: 101272458(STAT1)
ECB: 100069633(STAT1)
EPZ: 103548655(STAT1)
EAI: 106828796(STAT1)
MYB: 102243651(STAT1)
MYD: 102757059(STAT1)
HAI: 109393276(STAT1)
RSS: 109452057(STAT1)
PALE: 102886603(STAT1)
LAV: 100668424(STAT1)
TMU: 101357916
MDO: 100028917(STAT1)
SHR: 105749862(STAT1)
OAA: 100087266
GGA: 424044(STAT1)
MGP: 100544816(STAT1)
CJO: 107316322(STAT1)
APLA: 101795022 101802227(STAT1)
ACYG: 106039967(STAT1)
TGU: 100221342(STAT1)
GFR: 102036007(STAT1)
FAB: 101811260(STAT1)
PHI: 102100816(STAT1)
PMAJ: 107207405(STAT1)
CCW: 104693738(STAT1)
FPG: 101922205(STAT1)
FCH: 102054689(STAT1)
CLV: 102098106(STAT1)
EGZ: 104130544(STAT1)
AAM: 106492439(STAT1)
ASN: 102374439(STAT1)
AMJ: 102571738(STAT1)
PSS: 102462741(STAT1)
CMY: 102934663
CPIC: 101931440(STAT1)
ACS: 100558595(stat1)
PVT: 110083952(STAT1)
PBI: 103060112(STAT1)
XLA: 108703082 398324(stat1.L)
XTR: 780397(stat1)
NPR: 108798858(STAT1)
DRE: 30768(stat1a) 368481(stat1b)
IPU: 108259490 108266311(STAT1)
LCO: 104920795(stat1) 104926239 104931961(stat2)
MZE: 101476764(stat1) 101486905
CSEM: 103389515(stat1) 103392403
SASA: 100136558(STAT1) 100270812(stat2) 106586142
LCM: 102353760(STAT1) 102355078(STAT2)
CMK: 103176541(stat1) 103191066
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1502203
  Authors
Schindler C, Fu XY, Improta T, Aebersold R, Darnell JE Jr
  Title
Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha.
  Journal
Proc Natl Acad Sci U S A 89:7836-9 (1992)
DOI:10.1073/pnas.89.16.7836
  Sequence
[hsa:6772]

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