KEGG   ORTHOLOGY: K11222Help
Entry
K11222                      KO                                     

Name
STAT4
Definition
signal transducer and activator of transcription 4
Pathway
ko04217  Necroptosis
ko04630  JAK-STAT signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko05161  Hepatitis B
ko05200  Pathways in cancer
ko05321  Inflammatory bowel disease (IBD)
Module
M00684  JAK-STAT signaling
Disease
H01492  Systemic sclerosis
H01502  Sjogren syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    K11222  STAT4; signal transducer and activator of transcription 4
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11222  STAT4; signal transducer and activator of transcription 4
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K11222  STAT4; signal transducer and activator of transcription 4
 09160 Human Diseases
  09161 Cancers: Overview
   05200 Pathways in cancer
    K11222  STAT4; signal transducer and activator of transcription 4
  09163 Immune diseases
   05321 Inflammatory bowel disease (IBD)
    K11222  STAT4; signal transducer and activator of transcription 4
  09172 Infectious diseases: Viral
   05161 Hepatitis B
    K11222  STAT4; signal transducer and activator of transcription 4
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11222  STAT4; signal transducer and activator of transcription 4
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00684  JAK-STAT signaling
     K11222  STAT4; signal transducer and activator of transcription 4
Transcription factors [BR:ko03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11222  STAT4; signal transducer and activator of transcription 4
BRITE hierarchy
Genes
HSA: 6775(STAT4)
PTR: 100610925(STAT4)
PPS: 100972895(STAT4)
GGO: 101137064(STAT4)
PON: 100436344(STAT4)
NLE: 100596678(STAT4)
MCC: 693854(STAT4)
MCF: 101925110(STAT4)
CSAB: 103217530(STAT4)
RRO: 104675283(STAT4)
RBB: 108527864(STAT4)
CJC: 100402355(STAT4)
SBQ: 101030273(STAT4)
MMU: 20849(Stat4)
RNO: 367264(Stat4)
CGE: 100769249(Stat4)
NGI: 103736155(Stat4)
HGL: 101718558(Stat4)
CCAN: 109682739(Stat4)
OCU: 100344146(STAT4)
TUP: 102475477(STAT4)
CFA: 478845(STAT4)
AML: 100471596(STAT4)
UMR: 103659686(STAT4)
ORO: 101379077(STAT4)
FCA: 101080650(STAT4)
PTG: 102953648(STAT4)
AJU: 106979739(STAT4)
BTA: 515988(STAT4)
BOM: 102283979(STAT4)
BIU: 109575487(STAT4)
PHD: 102332485(STAT4)
CHX: 102189443(STAT4)
OAS: 101117562(STAT4)
SSC: 397261(STAT4)
CFR: 102509760(STAT4)
CDK: 105088786(STAT4)
BACU: 103013312(STAT4)
LVE: 103068832(STAT4)
OOR: 101272876(STAT4)
ECB: 100054693(STAT4)
EPZ: 103548657(STAT4)
EAI: 106828795(STAT4)
MYB: 102244347(STAT4)
MYD: 102757535(STAT4)
RSS: 109452079(STAT4)
PALE: 102886854(STAT4)
LAV: 100668145(STAT4)
TMU: 101351364
MDO: 100617910(STAT4)
OAA: 100087021
GGA: 768406(STAT4)
MGP: 100544968(STAT4)
CJO: 107316323(STAT4)
APLA: 101794819(STAT4)
ACYG: 106039968(STAT4)
TGU: 100224258(STAT4)
SCAN: 103814538(STAT4)
GFR: 102035832(STAT4)
FAB: 101811067(STAT4)
PHI: 102100630(STAT4)
PMAJ: 107207703(STAT4)
CCAE: 111931931(STAT4)
CCW: 104693739(STAT4)
FPG: 101922376(STAT4)
FCH: 102054863(STAT4)
CLV: 102097927(STAT4)
EGZ: 104130543(STAT4)
NNI: 104014266(STAT4)
ACUN: 113482457(STAT4)
AAM: 106492457(STAT4)
ASN: 102377767(STAT4) 102380863
AMJ: 102571515(STAT4)
PSS: 102463308(STAT4)
CMY: 102934439(STAT4)
CPIC: 101932470(STAT4)
ACS: 100556501(stat4)
PVT: 110083962(STAT4)
PBI: 103060923(STAT4)
PMUR: 107289221(STAT4)
GJA: 107116065
XLA: 108701493(stat4.L)
XTR: 100496013(stat4)
DRE: 368519(stat4)
SGH: 107565030(stat4) 107602137
IPU: 108266777(stat4)
PHYP: 113525972(stat4)
AMEX: 103031322(stat4)
TRU: 101068057(stat4)
LCO: 104920796(stat4)
MZE: 101482935(stat4)
OLA: 101161521
XMA: 102223424(stat4)
PRET: 103460697
NFU: 107397170(stat4)
KMR: 108250769(stat4)
CSEM: 103392405(stat4)
LCF: 108897211
SDU: 111218102(stat4)
HCQ: 109517577(stat4)
BPEC: 110156165(stat4)
MALB: 109971734
SASA: 100380385(stat4) 106586145
SALP: 111973981 111974244(stat4)
ELS: 105022416(stat4)
LCM: 102353506(STAT4)
CMK: 103176542(stat4)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7545930
  Authors
Zhong Z, Wen Z, Darnell JE Jr
  Title
Stat3 and Stat4: members of the family of signal transducers and activators of transcription.
  Journal
Proc Natl Acad Sci U S A 91:4806-10 (1994)
DOI:10.1073/pnas.91.11.4806
  Sequence
[mmu:20849]
Reference
  Authors
Lim CP, Cao X
  Title
Structure, function, and regulation of STAT proteins.
  Journal
Mol Biosyst 2:536-50 (2006)
DOI:10.1039/b606246f

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