KEGG   ORTHOLOGY: K11224Help
Entry
K11224                      KO                                     

Name
STAT5B
Definition
signal transducer and activator of transcription 5B
Pathway
ko04012  ErbB signaling pathway
ko04062  Chemokine signaling pathway
ko04217  Necroptosis
ko04630  Jak-STAT signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04917  Prolactin signaling pathway
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05161  Hepatitis B
ko05162  Measles
ko05166  HTLV-I infection
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
ko05220  Chronic myeloid leukemia
ko05221  Acute myeloid leukemia
ko05223  Non-small cell lung cancer
Module
M00684  JAK-STAT signaling
Disease
H00931  Growth hormone insensitivity with immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04630 Jak-STAT signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
 Cellular Processes
  Cell growth and death
   04217 Necroptosis
    K11224  STAT5B; signal transducer and activator of transcription 5B
 Organismal Systems
  Immune system
   04658 Th1 and Th2 cell differentiation
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04659 Th17 cell differentiation
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04062 Chemokine signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
  Endocrine system
   04917 Prolactin signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05203 Viral carcinogenesis
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05221 Acute myeloid leukemia
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05220 Chronic myeloid leukemia
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05223 Non-small cell lung cancer
    K11224  STAT5B; signal transducer and activator of transcription 5B
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    K11224  STAT5B; signal transducer and activator of transcription 5B
  Infectious diseases
   05166 HTLV-I infection
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05162 Measles
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05161 Hepatitis B
    K11224  STAT5B; signal transducer and activator of transcription 5B
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00684  JAK-STAT signaling
     K11224  STAT5B; signal transducer and activator of transcription 5B
Transcription factors [BR:ko03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11224  STAT5B; signal transducer and activator of transcription 5B
BRITE hierarchy
Genes
HSA: 6777(STAT5B)
PTR: 454679(STAT5B)
PPS: 100989105(STAT5B)
GGO: 101128930(STAT5B)
PON: 100462537(STAT5B)
NLE: 100602489(STAT5B)
MCC: 106994047(STAT5B) 709760(STAT5B)
MCF: 102127060(STAT5B)
CSAB: 103243413(STAT5B)
RRO: 104680321(STAT5B)
RBB: 108518352
CJC: 100388552(STAT5B)
SBQ: 101043203(STAT5B)
MMU: 20851(Stat5b)
RNO: 25126(Stat5b)
CGE: 100750571(Stat5b)
NGI: 103735893(Stat5b)
HGL: 101722721(Stat5b)
CCAN: 109692057
OCU: 100348267(STAT5B)
TUP: 102492323(STAT5B)
CFA: 490969
AML: 100479246(STAT5B)
UMR: 103672570(STAT5B)
ORO: 101372217(STAT5B)
FCA: 101090663(STAT5B)
PTG: 102972489(STAT5B)
AJU: 106972565(STAT5B)
BTA: 282376(STAT5B)
BOM: 102283211(STAT5B)
BIU: 109573773(STAT5B)
PHD: 102339004(STAT5B)
CHX: 102176415(STAT5B)
OAS: 101122961(STAT5B)
SSC: 397340(STAT5B)
CFR: 102511001(STAT5B)
CDK: 105090456(STAT5B)
LVE: 103082258(STAT5B)
OOR: 101280265(STAT5B)
ECB: 100052954
EPZ: 103550391
EAI: 106826362(STAT5B)
MYB: 102241062(STAT5B)
RSS: 109455746
PALE: 102884882(STAT5B)
LAV: 100669299(STAT5B)
TMU: 101354148
MDO: 100011470(STAT5B)
SHR: 100920307
OAA: 100092915
GGA: 395556(STAT5B)
MGP: 100546986
CJO: 107325190
APLA: 101790203(STAT5B)
ACYG: 106047991
TGU: 100222731(STAT5B)
GFR: 102036670(STAT5B)
FAB: 101808879(STAT5B)
PHI: 102101483(STAT5B)
PMAJ: 107215121
CCW: 104697815
FPG: 101918263(STAT5B)
FCH: 102053699(STAT5B)
CLV: 102098622
EGZ: 104135093
ASN: 102380420(STAT5B)
AMJ: 102575674(STAT5B) 109280378
ACS: 100566752(stat5b)
PVT: 110074911
PBI: 103049078(STAT5B)
GJA: 107111494
XLA: 399176(stat5b.L) 414637(stat5b.S)
XTR: 100495240(stat5b)
NPR: 108788932
DRE: 369197(stat5a) 445474(stat5b)
IPU: 108273804(Stat5b) 108279147(STAT5B)
TRU: 101071345
LCM: 102348150(STAT5B)
CMK: 103189177
CIN: 778770(stat-b)
SPU: 576433
SKO: 100313741
DME: Dmel_CG4257(Stat92E)
DSI: Dsimw501_GD20060(Dsim_GD20060)
MDE: 101895093
AGA: AgaP_AGAP000099(STAT2) AgaP_AGAP010423(STAT_ANOGA)
AAG: 5572256
AME: 413742(STAT92E-like)
BIM: 100743540
BTER: 100647789
SOC: 105193817
AEC: 105148183
ACEP: 105624336
PBAR: 105433521
HST: 105184844
CFO: 105254529
LHU: 105672556
PGC: 109854643
NVI: 100121885
TCA: 657965(Stat)
DPA: 109540291
NVL: 108559383
BMOR: 100302627(Stat)
PRAP: 110992522
API: 100161101
CEL: CELE_Y51H4A.17(sta-1)
CBR: CBG13675(Cbr-sta-1)
BMY: Bm1_36470
TSP: Tsp_04456
CRG: 105332473
OBI: 106873988
ADF: 107338381
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8732682
  Authors
Silva CM, Lu H, Day RN
  Title
Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone.
  Journal
Mol Endocrinol 10:508-18 (1996)
DOI:10.1210/mend.10.5.8732682
  Sequence
[hsa:6777]

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