KEGG   ORTHOLOGY: K11407Help
Entry
K11407                      KO                                     

Name
HDAC6
Definition
histone deacetylase 6 [EC:3.5.1.98]
Pathway
ko05034  Alcoholism
ko05165  Human papillomavirus infection
ko05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09161 Cancers
   05203 Viral carcinogenesis
    K11407  HDAC6; histone deacetylase 6
  09164 Substance dependence
   05034 Alcoholism
    K11407  HDAC6; histone deacetylase 6
  09167 Infectious diseases
   05165 Human papillomavirus infection
    K11407  HDAC6; histone deacetylase 6
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatase and associated proteins
    K11407  HDAC6; histone deacetylase 6
  09182 Protein families: genetic information processing
   03019 Messenger RNA Biogenesis
    K11407  HDAC6; histone deacetylase 6
   04131 Membrane trafficking
    K11407  HDAC6; histone deacetylase 6
   03036 Chromosome and associated proteins
    K11407  HDAC6; histone deacetylase 6
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     K11407  HDAC6; histone deacetylase 6
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K11407  HDAC6; histone deacetylase 6
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     K11407  HDAC6; histone deacetylase 6
Membrane trafficking [BR:ko04131]
 Autophagy
  Aggrephagy
   Other aggrephagy associated proteins
    K11407  HDAC6; histone deacetylase 6
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class II HDACs
     K11407  HDAC6; histone deacetylase 6
BRITE hierarchy
Other DBs
GO: 0004407
Genes
HSA: 10013(HDAC6)
PTR: 100610515(HDAC6)
PPS: 100979180(HDAC6)
GGO: 101148332(HDAC6)
PON: 100459509(HDAC6)
NLE: 100589125(HDAC6)
MCC: 711363(HDAC6)
MCF: 101926822(HDAC6)
CSAB: 103231941(HDAC6)
RRO: 104660656(HDAC6)
RBB: 108517465(HDAC6)
CJC: 100414028(HDAC6)
SBQ: 101053695(HDAC6)
MMU: 15185(Hdac6)
RNO: 108348065 84581(Hdac6)
CGE: 100763688(Hdac6)
NGI: 103741648(Hdac6)
HGL: 101708442(Hdac6)
CCAN: 109692146(Hdac6)
OCU: 100354982(HDAC6)
TUP: 102487728(HDAC6)
CFA: 480907(HDAC6)
AML: 100478725(HDAC6)
UMR: 103668837(HDAC6)
ORO: 101372755(HDAC6)
FCA: 101084086(HDAC6)
PTG: 102950287(HDAC6)
AJU: 106989010(HDAC6)
BTA: 513602(HDAC6)
BOM: 102270629(HDAC6)
BIU: 109555290(HDAC6)
PHD: 102326835(HDAC6)
CHX: 102183307(HDAC6) 108634294
OAS: 101109245(HDAC6)
SSC: 100621798(HDAC6)
CFR: 102507599(HDAC6)
CDK: 105103305(HDAC6)
BACU: 103007075(HDAC6)
LVE: 103074668(HDAC6)
OOR: 101279254(HDAC6)
ECB: 100062208(HDAC6)
EPZ: 103544928(HDAC6) 103545120
EAI: 106826974(HDAC6)
MYB: 102261327(HDAC6)
MYD: 102764898(HDAC6)
HAI: 109374787(HDAC6)
RSS: 109436055(HDAC6) 109440892
PALE: 102887872(HDAC6)
LAV: 100677211(HDAC6)
TMU: 101347918
MDO: 100018936(HDAC6)
OAA: 100090183(HDAC6)
PHI: 102112779(HDAC6)
PMAJ: 107198877(HDAC6)
ASN: 102371839(HDAC6)
AMJ: 102571581(HDAC6)
CMY: 102933682
CPIC: 101932281(HDAC6)
ACS: 100560628(hdac6)
PVT: 110090616(HDAC6)
PBI: 103061412(HDAC6)
XLA: 380178(hdac6.L)
XTR: 100379853(hdac6)
NPR: 108788253(HDAC6)
DRE: 565482(hdac6)
IPU: 108265870(hdac6)
AMEX: 103045033(hdac6)
TRU: 101079879(hdac6)
LCO: 104939299(hdac6)
NCC: 104951588(hdac6)
MZE: 101478640(hdac6)
OLA: 101163380(hdac6)
XMA: 102236214(hdac6)
PRET: 103460243(hdac6)
NFU: 107391463(hdac6)
CSEM: 103384397(hdac6)
LCF: 108890566(hdac6)
HCQ: 109510379(hdac6)
BPEC: 110154455(hdac6)
SASA: 106572925(hdac6) 106572926
ELS: 105028329(hdac6)
SFM: 108934846(hdac6)
LCM: 102361123(HDAC6)
SPU: 100893415
APLC: 110985632
SKO: 102803980
DME: Dmel_CG6170(HDAC6)
DSI: Dsimw501_GD17207(Dsim_HDAC6)
MDE: 101900790
AAG: 5568333
AME: 725938(HDAC6) 727620
BIM: 100744197
BTER: 100646470
SOC: 105202226
AEC: 105149380
ACEP: 105621845
PBAR: 105425482
HST: 105192036
CFO: 105249732
LHU: 105670581
PGC: 109858202
NVI: 100119821
TCA: 103313051
DPA: 109537190
NVL: 108569080
BMOR: 101741658
PMAC: 106715989
PRAP: 111001863
PXY: 105390228
DNX: 107164622
ZNE: 110841406
CEL: CELE_F41H10.6(hda-6)
BMY: Bm1_29305
MYI: 110453222
LAK: 106172630
SHX: MS3_06742
EPA: 110245707
ADF: 107329036
AQU: 100632187
ATH: AT3G18520(HDA15) AT5G61060(HDA05) AT5G61070(HDA18)
LJA: Lj0g3v0089689.1(Lj0g3v0089689.1) Lj4g3v1719690.1(Lj4g3v1719690.1) Lj4g3v1787130.1(Lj4g3v1787130.1) Lj4g3v1787130.2(Lj4g3v1787130.2) Lj4g3v1787130.3(Lj4g3v1787130.3)
DOSA: Os07t0164100-01(Os07g0164100) Os07t0602200-01(Os07g0602200)
ATS: 109747977(LOC109747977) 109767653(LOC109767653) 109779458(LOC109779458)
ZMA: 541883(rpd3) 541972(hda110)
OLU: OSTLU_87707(HDA3505)
APRO: F751_4212
SCE: YNL021W(HDA1)
ERC: Ecym_3324
KMX: KLMA_80132(HDA1)
NCS: NCAS_0G03800(NCAS0G03800)
NDI: NDAI_0G00650(NDAI0G00650)
TPF: TPHA_0C03390(TPHA0C03390)
TBL: TBLA_0B06950(TBLA0B06950)
TDL: TDEL_0G02160(TDEL0G02160)
KAF: KAFR_0H03320(KAFR0H03320)
CAL: CAALFM_CR02050CA(HDA1)
CDU: CD36_26960(HDA1)
CAUR: QG37_01615
SLB: AWJ20_1220(HDA1)
NCR: NCU01525(hda-1)
NTE: NEUTE1DRAFT147039(NEUTE1DRAFT_147039)
MGR: MGG_01076
NHE: NECHADRAFT_106321(HDA2102)
MAW: MAC_08042
MAJ: MAA_05326
CMT: CCM_06710
BFU: BCIN_15g02130(Bchda1)
MBE: MBM_05498
ANI: AN8042.2
ANG: ANI_1_258144(An16g01840)
ABE: ARB_00830
PTE: PTT_13889
ZTR: MYCGRDRAFT_37223(HDA2404)
NPA: UCRNP2_81
SPO: SPBC800.03(clr3)
CNE: CNC00780
CNB: CNBC6490
LBC: LACBIDRAFT_316459(HDA16207)
ABP: AGABI1DRAFT127061(AGABI1DRAFT_127061)
ABV: AGABI2DRAFT118070(AGABI2DRAFT_118070)
MGL: MGL_0270
SMIN: v1.2.021912.t1(symbB.v1.2.021912.t1) v1.2.027638.t1(symbB.v1.2.027638.t1) v1.2.028973.t1(symbB.v1.2.028973.t1)
SPAR: SPRG_09376
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Olzmann JA, Li L, Chudaev MV, Chen J, Perez FA, Palmiter RD, Chin LS
  Title
Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6.
  Journal
J Cell Biol 178:1025-38 (2007)
DOI:10.1083/jcb.200611128
  Sequence
[hsa:10013]
Reference
  Authors
Grozinger CM, Hassig CA, Schreiber SL
  Title
Three proteins define a class of human histone deacetylases related to yeast Hda1p.
  Journal
Proc Natl Acad Sci U S A 96:4868-73 (1999)
DOI:10.1073/pnas.96.9.4868
  Sequence
[hsa:10013]

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